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世界核心医学期刊文摘（心脏病学分册） 2006年第11期2卷 37-38页

作者： Powell B.D. Redfield M.M. Bybee K.A. C.S. Rihal 黄浙勇 Division of cardiovascular Diseases Mayo Clinic Rochester MN United States Dr.

Obese patients frequently complain of dyspnea. Deconditioning and altered left ventricular(LV) systolic or diastolic function with elevated filling pressures may contribute to dyspnea. This study analyzed 4,281 patients who underwent diagnostic coronary angiography from January 1, 1995, to December 31, 2000. No patients had coronary artery stenoses >50%of the luminal diameter, and all underwent echocardiography within the same 6-year period. The association between body mass index(BMI) and LV structure and systolic and diastolic function was examined. All analyses controlled for age and gender, with the effect size for BMI expressed using a standardized coefficient(sc). A higher BMI was associated with greater LV mass(sc 0.18, pckness(sc 0.17, pstolic diameter(sc 0.07, pstroke volume increased with a higher BMI(sc 0.12, p=0.001), but there was no association between BMI and the ejection fraction(sc 0.003, p=0.81). Hemodynamic data from invasive studies showed an association between a higher BMI and increased LV end-diastolic pressure(mean 17 mm Hg for BMIs 24 mm Hg for BMI ≥40 kg/m2; sc 0.18, pch persisted after controlling for end-diastolic volume(sc 0.22, psity was associated with ventricular remodeling, which may normalize wall stress while increasing stroke volume to match metabolic demand. Obesity was not associated with decreased systolic function. However, obesity was associated with increased LV end-diastolic pressure, which suggests an association between obesity and diastolic dysfunction. In conclusion, ventricular remodeling, LV diastolic dysfunction, and elevated filling pressures may contribute to the prevalence of heart failure in obese patients.

关键词：舒张功能异常左室重构心室重构舒张期末容积冠状动脉造影室壁厚度左室结构室壁应力呼吸困难

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世界核心医学期刊文摘(心脏病学分册) 2007年第9期 44-45页

作者： Lavi s. Mcconnell J.P. rihal c.s. A. Lerman 孙凯 Division of cardiovascular Diseases Mayo clinic Mary Brigh 4-523 First st sW Rochester MN 55905 United states

背景:脂蛋白相关性磷脂酶A2(Lp-PLA2)是一种新型标记物,参与了血管炎症。炎症亦与冠状动脉粥样硬化相关。检验如下假设:冠状动脉局部的Lp-PLA2产量在早期冠状动脉粥样硬化患者中增强,且与局部内皮功能相关。方法和结果:纳入15例轻度冠... 详细信息

背景:脂蛋白相关性磷脂酶A2(Lp-PLA2)是一种新型标记物,参与了血管炎症。炎症亦与冠状动脉粥样硬化相关。检验如下假设:冠状动脉局部的Lp-PLA2产量在早期冠状动脉粥样硬化患者中增强,且与局部内皮功能相关。方法和结果:纳入15例轻度冠状动脉粥样

关键词：冠状动脉粥样硬化冠状动脉循环血液循环 A2 内皮功能溶血磷脂脂蛋白磷脂酶脂肪酶人类胆碱三甲基烷基铵相关性障碍产量

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Open charm mesons and charmonia in magnetized strange hadronic matter

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chinese Physics c 2022年第8期46卷 91-113页

作者： Amal Jahan c.s. Amruta Mishra Department of Physics Indian Institute of TechnologyNew Delhi-110016India

We investigate the in-medium masses of open charm mesons(D(D^(0),D^(+)),■(■^(0),D^(-)),D_(s)(D_(s)^(+),D_(s)^(-)))and charmonium states(J/ψ,ψ(3686),ψ(3770),χ_(c0),χ_(c2)) in strongly magnetized isospin asymmetric.s.range hadronic matter using a chiral effective model.In the presence of a magnetic field,the number and scalar densities of charged baryons have contributions from Landau energy levels.The mass modifications of open charm mesons result from their interactions with nucleons,hyperons,and the scalar fields(the non-strange field σ,strange field c and isovector field δ) in the presence of a magnetic field.The mass modifications of the charmonium states result from the modification of gluon condensates in a medium simulated by the variation in the dilaton field(χ) in the chiral effective model.The effec.s.of finite quark masses are also incorporated in the trace of the energy-momentum tensor in quantum chromodynamics to investigate the mass shifts of charmonium states.The in-medium masses of open charm mesons and charmonia are observed to decrease with an increase in baryon density.The charged D^(+),D^(-),Z_(s)^(+),and D_(s)^(-)mesons have additional positive mass shifts due to Landau quantization in the presence of a magnetic field.The effec.s.of the strangeness fraction are observed to be more dominant for ■ mesons compared with D mesons.The mass shifts of charmonia are observed to be larger in hyperonic media compared with nuclear media when the effect of the finite quark mass term is neglected.These medium mass modifications can have observable consequenc.s.on the production of the open charm mesons and charmonia in high-energy asymmetric heavy-ion collision experiments.