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Bone cement adhesion on ceramic surfaces—Surface activation of retention surfaces of knee endoprostheses by atmospheric pressure plasma *** surface treatment

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Journal of Advanced ceramics 2016年第2期5卷 137-144页

作者： B.marx c.marx R.marx U.REISGEN D.c.WIRTZ ISF Welding and Joining Institute RWTH Aachen University Pontstrasse 49 52062 Aachen GermanyCC&A Medical Components Ltd. Center for Biomedical Engineering Pauwelsstrasse 17 52074 Aachen Germany cc&A Medical components Ltd. Center for Biomedical Engineering Pauwelsstrasse 17 52074 Aachen Germany ISF Welding and Joining Institute RWTH Aachen University Pontstrasse 49 52062 Aachen Germany Orthopaedics and Traumatology clinic University Hospital Bonn Sigmund-Freud-Strasse 25 53127 Bonn Germany

cocrMo alloys are contraindicated for allergy sufferers. For these patients, uncemented and cemented prostheses made of titanium alloy are indicated. Knee prostheses machined from that alloy, however, may have poor tribological behavior. Therefore, for allergy sufferers, knee replacements in form of cemented high-strength oxide ceramic prostheses which reveal excellent tribological behavior are suitable. In addition, the rate of particle induced aseptic loosening may be reduced. For adhesion of bone cement, the smooth ceramic surface, however, exposes inefficient mechanical retention spots as compared with a textured metal surface. Undercuts generated by corundum blasting, which in the short and intermediate term are highly efficient on a cocrMo surface, are not appropriate on a ceramic surface due to the brittleness of ceramics. The corresponding textures may initiate cracks which will weaken the strength of a ceramic prosthesis. Due to the lack of textures, mechanical retention is poor or even not existent. Micromotions are facilitated and early aseptic loosening is predictable. Instead silicoating of the ceramic surface will allow specific adhesion and result in better hydrolytic stability of bonding, thereby preventing early aseptic loosening. Silicoating, however, presupposes a clean and chemically active surface which may be achieved by atmospheric plasma or thermal surface treatment. In order to evaluate the effectiveness of silicoating, the bond strengths of atmospheric plasma versus thermal surface treated and silicoated ZPTA (zirconia platelets toughened alumina) surfaces were compared with “as-fired” surfaces by utilizing TiAlV probes (diameter: 6 mm) for traction-adhesive strength test. After preparing samples for traction-adhesive strength test (sequence: ceramic substrate, silicate layer and penetrated silane, protective lacquer (PolyMA), bone cement, TiAlV probe), they were aged up to 150 days at 37°c in Ringer’s solution. The bond strengths observed

关键词： total knee replacement out of oxide ceramics aseptic loosening allergenic potential atmospheric plasma treatment silicoating hydrolytic stability

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1979—1983年间钻井技术发展情况的分析

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国外地质勘探技术 1985年第4期 24-27页

作者： c.marx H.KRZL 杨志豪

自1978年发表了有关钻井技术发展概况的论文以来,在近四、五年间的专业杂志上共发表了400多篇有关钻井技术发展情况的文章,这些文章有助于了解当前钻井技术发展的水平。1978年所预测的发展趋势有一部

关键词：钻井技术辅助设备加重钻杆涡轮钻造斜器水平钻进定向钻进钻井机械防喷器控制设备

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水基钻井泥浆耐温性能的试验研究

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探矿工程 1989年第2期 64-64页

作者： M.A.Faraz c.marx 张伟

这项研究涉及超深井泥浆,在西德克劳斯塔尔工业大学深钻和采油技术研究所中进行。其目的是要探讨采用不同的泥浆材料(即粘土和聚合物添加剂)时,水基钻井泥浆的耐温性能(温度稳定性)。最高试验温度达250℃。

关键词：钻井泥浆耐温性能聚合物添加剂超深井采油技术泥浆性能塑性粘度试验研究斯塔尔加重材料

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优化3.0 T前列腺T2WI螺旋桨技术对病灶检测和PI-RADS分类的影响

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国际医学放射学杂志 2018年第2期 235-235页

作者： M.Meier-Schroers c.marx F.c.Schmeel K.Wolter J.Gieseke W.Block A.M.Sprinkart 孙成凤 Department of Radiology University Hospital Bonn

摘要目的评估优化后前列腺T2WI螺旋桨技术（Rev PROP）替代快速自旋回波（TSE）的可行性。材料与方法利用3.0 T MRI对50例病人共55个可疑癌性病变进行前瞻

关键词：螺旋桨技术癌性病变前列腺

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Status and prospects for symmetric organic redox flow batteries

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Journal of Energy chemistry 2025年第1期100卷 125-143页

作者： Md Al Raihan c.Adam Dyker Department of chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. This review explores the growing field of symmetric organic redox flow batteries(ORFBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORFBs involve a single bipolar species for both electrodes. This review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. This should guide new research directions and advance the development of practical symmetric ORFBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

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Acquired sensorineural hearing loss,oxidative stress,and microRNAs

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Neural Regeneration Research 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez Ru c.Guo Division of Otolaryngology–Head&Neck Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Neck Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada Faculty of Medicine–The University of British columbia VancouverBCCanada

Hearing loss is the third leading cause of human ***-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health ***-induced,ototoxic,and idiopathic sudden sensorineural are other less common types of acquired hearing *** etiology of these conditions is complex and multi-fa ctorial involving an interplay of genetic and environmental *** stress has recently been proposed as a likely linking cause in most types of acquired sensorineural hearing *** non-coding RNA sequences known as microRNAs(miRNAs)have increasingly been shown to play a role in cellular hypoxia and oxidative stress responses including promoting an apoptotic *** hair cell death is a central histopathological finding in sensorineural hearing *** these cells do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDLINE,Web of Science core collection,and *** databases over the period August 1,2018 to July 31,2023 were searched with"hearing loss,""hypoxamiRs,""hypoxia,""microRNAs,""ischemia,"and"oxidative stress"text words for English language primary study publications or registered clinical *** red clinical trials known to the senior author we re also assessed.A total of 222studies were thus *** excluding duplicates,editorials,retra ctions,secondary research studies,and non-English language articles,39 primary studies and clinical trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subject journal articles and 8 registered clinical trial database entries which form the basis of this narrative *** miR-34a and miR-29b levels increase with age in *** miRNAs were demonstrated in human neuroblastoma and murine cochlear cell lines to target Sirtuin 1/peroxisome proliferato r-activated receptor gamma coactivator-1-alpha(SIRT1/P Gc-1α),SIRT

关键词： hearing loss hypoxia microRNAs oxidative stress sensorineural

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Multiple sclerosis is at a checkpoint: advancing the program

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Neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon c.Smith Jessica L.Williams Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biological Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(cNS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage

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Genotype frequency of gelatinase B c-1562 T polymorphism in coronary heart disease and myocardial infarction

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Journal of Geriatric cardiology 2004年第2期1卷 114-118页

作者： Dieter Niederacher Roger marx Thomas Scheffold Rolf Michael Klein Molecular Genetics Laboratory of the Gynecology Division Henrich-Heine University DuesseldorfGermany Heart center Wuppertal University of Witten-HerdeckeWuppertalGermany

Background One of the characteristics of atherosclerosis is a change in the content of extracellular matrix in the arterial wall. Gelatinase B, a member of the family of matrix metalloproteinase, can regulate extracellular matrix metabolismand play a role in the pathogenesis of atherosclerosis, coronary heart disease (cHD) and myocardial infarction (MI). Gelatinase B is polymorphic due to a c to T change at the position -1562 bp in the promoter *** relationship with gene product concentration in serum and its role in mediating the risk of cHD and MI in Germans is still unknown. Methods We enrolled 102 controls and 322 patients with angiographically documented cHD,including a sub-group of 173 patients with acute or chronic MI and 80 patients with acute coronary syndrome (AcS).All patients and controls were Germans and genotyped by polymerase chain reaction and digestion with SphI. Results We found that several classical risk factors for cHD and MI, including hypercholesterolemia and cigarette smoking,were significantly increased in cHD and MI patients compared with controls. Serum levels of gelatinase B and tissue inhibitor of metalloproteinase-1 were increased in the peripheral blood of patients with acute coronary syndrome. No significant differences in genotype or allelic frequencies between cHD, MI and control subjects of either men or women were found. Our search for a possible association of the polymorphisms with cHD and MI by logistic regression analysis was also negative. The serum concentrations of gelatinase B showed no differences between genotypes. conclusions Our data showed that gelatinase B might provide an index of plaque activity in AcS, but gelatinase B protein was not affected by genotypes. Also, the T variant of gelatinase B was not associated with cHD or MI in Germans. (J Geriatr cardiol 2004;1(2):114-118.)

关键词： gelatinase B gene polymorphism coronary heart disease myocardial infarction gelatinase B protein

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Effect of age and different doses of dietary vitamin E on breast meat qualitative characteristics of finishing broilers

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Animal Nutrition 2021年第1期7卷 163-167页

作者： Vivian Vieira Francielle O.marx Lucas S.Bassi Marley c.Santos Alexandre Oba Simone Gisele de Oliveira Alex Maiorka Federal University of Paraná Curitiba80035-050Brazil State University of Londrina Londrina86055-900Brazil

The supplementation of vitamin E on broiler chicken diets is essential to the prevention of lipid oxidation reactions in the meat and improvement of meat *** objective of this study was to assess the effect of different doses of dietary vitamin E on breast meat quality of broiler chickens in the finishing *** doses of vitamin E were used(30,90,150,210,and 270 mg/kg feed)in broilers'diets from 42 to 54 d of age.A completely randomized design was conducted,followed by a split-plot,where the vitamin E dose was considered as the whole plot,and broilers'age at slaughter was the *** meat quality was assessed at 4 different ages(45,48,51,and 54 d old),using 50 birds per age,totaling 200 *** quality characteristics evaluated were:pH at 24 h post mortem,color(brightness,redness,and yellowness),water holding capacity,cooking loss,shear force,and lipid *** was no interaction between age and dose of vitamin E for meat quality characteristics(P>0.05).The age at slaughter had a quadratic effect(Pce value was higher in breast meat of birds slaughtered at later ages(Pct was *** increased linearly(Pcooking loss,and lipid *** this study,increasing vitamin E doses in the finishing period increased the brightness of broiler breast meat,whereas slaughtering at later ages resulted in greater meat pH and shear force value.

关键词： Alpha-tocopherol Broiler chicken Meat quality Oxidation Vitamin

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Ultra‑Transparent and Multifunctional IZVO Mesh Electrodes for Next‑Generation Flexible Optoelectronics

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Nano-Micro Letters 2025年第1期17卷 293-309页

作者： Kiran A.Nirmal Tukaram D.Dongale Atul c.Khot chenjie Yao Nahyun Kim Tae Geun Kim School of Electrical Engineering Korea UniversityAnam‑ro 145Seongbuk‑guSeoulRepublic of Korea computational Electronics and Nanoscience Research Laboratory School of Nanoscience and BiotechnologyShivaji UniversityKolhapur 416004India

Mechanically durable transparent electrodes are essential for achieving long-term stability in flexible optoelectronic ***,they are crucial for applications in the fields of energy,display,healthcare,and soft *** meshes represent a promising alternative to traditional,brittle,metal oxide conductors due to their high electrical conductivity,optical transparency,and enhanced mechanical *** this paper,we present a simple method for fabricating an ultra-transparent conducting metal oxide mesh electrode using selfcracking-assisted *** this method,we produced an electrode with ultra-transparency(97.39%),high conductance(Rs=21.24Ωsq^(−1)),elevated work function(5.16 eV),and good mechanical *** also evaluated the effectiveness of the fabricated electrodes by integrating them into organic photovoltaics,organic light-emitting diodes,and flexible transparent memristor devices for neuromorphic computing,resulting in exceptional device *** addition,the unique porous structure of the vanadium-doped indium zinc oxide mesh electrodes provided excellent flexibility,rendering them a promising option for application in flexible optoelectronics.

关键词： Self-cracking template Vanadium-doped indium zinc oxide mesh Organic solar cells Organic light-emitting diodes Flexible transparent memory

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