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结直肠肝转移延迟期钆MRI强化程度与非手术病人的总体生存率相关

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国际医学放射学杂志 2019年第5期 625-625页

作者： H.M.c.cheung J.K.Kim J.Hudson N.coburn P.J.Karanicolas c.law 朱项阳 Department of Medical Imaging Sunnybrook Health Sciences Centre University of Toronto

摘要目的确定结直肠肝转移(cRcLM)延迟期钆MRI强化程度是否与非手术病人的整体生存有关。材料与方法本回顾性研究得到了伦理委员会的批准。在2006年3月1

关键词：强化程度非手术 MRI 手术病人延迟期肝转移结直肠总体生存率

Status and prospects for symmetric organic redox flow batteries

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Journal of Energy chemistry 2025年第1期100卷 125-143页

作者： Md Al Raihan c.Adam Dyker Department of chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. This review explores the growing field of symmetric organic redox flow batteries(ORFBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORFBs involve a single bipolar species for both electrodes. This review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. This should guide new research directions and advance the development of practical symmetric ORFBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

Interference Suppression and Jitter Elimination Ability-Based Adaption Tracking Guidance for Robotic Fishes

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IEEE/cAA Journal of Automatica Sinica 2025年第1期 126-137页

作者： Dongfang Li Jie Huang Rob law Xin Xu Limin Zhu Edmond Q.Wu IEEE the School of Electrical Engineering and Automation Fuzhou University the Key Laboratory of System control and Information Processing Ministry of Education the School of Electrical Engineering and Automation Fuzhou University 5G+Industrial Internet Institute Fuzhou University the University of Macau the college of Mechatronics and Automation National University of Defense Technology the School of Mechanical Engineering Shanghai Jiao Tong University the Department of computer Science and Engineering Shanghai Jiao Tong University

This work presents an adaptive tracking guidance method for robotic fishes. The scheme enables robots to suppress external interference and eliminate motion jitter. An adaptive integral surge line-of-sight guidance rule is designed to eliminate dynamics interference and sideslip issues. Limited-time yaw and surge speed observers are reported to fit disturbance variables in the model. The approximation values can compensate for the system's control input and improve the robots' tracking ***, this work develops a terminal sliding mode controller and third-order differential processor to determine the rotational torque and reduce the robots' run jitter. Then, Lyapunov's theory proves the uniform ultimate boundedness of the proposed method. Simulation and physical experiments confirm that the technology improves the tracking error convergence speed and stability of robotic fishes.

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Acquired sensorineural hearing loss,oxidative stress,and microRNAs

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Neural Regeneration Research 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez Ru c.Guo Division of Otolaryngology–Head&Neck Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Neck Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada Faculty of Medicine–The University of British columbia VancouverBCCanada

Hearing loss is the third leading cause of human ***-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health ***-induced,ototoxic,and idiopathic sudden sensorineural are other less common types of acquired hearing *** etiology of these conditions is complex and multi-fa ctorial involving an interplay of genetic and environmental *** stress has recently been proposed as a likely linking cause in most types of acquired sensorineural hearing *** non-coding RNA sequences known as microRNAs(miRNAs)have increasingly been shown to play a role in cellular hypoxia and oxidative stress responses including promoting an apoptotic *** hair cell death is a central histopathological finding in sensorineural hearing *** these cells do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDLINE,Web of Science core collection,and *** databases over the period August 1,2018 to July 31,2023 were searched with"hearing loss,""hypoxamiRs,""hypoxia,""microRNAs,""ischemia,"and"oxidative stress"text words for English language primary study publications or registered clinical *** red clinical trials known to the senior author we re also assessed.A total of 222studies were thus *** excluding duplicates,editorials,retra ctions,secondary research studies,and non-English language articles,39 primary studies and clinical trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subject journal articles and 8 registered clinical trial database entries which form the basis of this narrative *** miR-34a and miR-29b levels increase with age in *** miRNAs were demonstrated in human neuroblastoma and murine cochlear cell lines to target Sirtuin 1/peroxisome proliferato r-activated receptor gamma coactivator-1-alpha(SIRT1/P Gc-1α),SIRT

关键词： hearing loss hypoxia microRNAs oxidative stress sensorineural

Osmotic concentration of succinic acid by forward osmosis:Influence of feed solution pH and evaluation of seawater as draw solution

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chinese Journal of chemical Engineering 2018年第5期26卷 976-983页

作者： Jeng Yih law Abdul Wahab Mohammad Department of chemical and Process Engineering Faculty of Engineering and Built Environment Universiti Kebangsaan Malaysia Section of chemical Engineering Technology Universiti Kuala Lumpur Malaysian Institute of Chemical & Bioengineering Technology

In this study, we investigated the essential role of feed solution pH so as to gain insights into the transport mechanisms of succinic acid concentration by osmotically-driven forward osmosis （FO） process. FO performances including water flux and bidirectional transport of succinate and chloride anions were systematically examined using cellulose triacetate-based FO membrane. Additionally, real seawater was explored as draw solution. Experimental results revealed that the pH-dependent speciation of succinic acid can affect the FO performances. Ionization of succinic acid at higher solution pH enhanced the osmotic pressure of feed solution, thus leading to lower water flux performance. A strong effect was pointed out on the succinate rejection for which nearly 100% rejections were achieved at pH above its pKa2 value. The rejection of succinate increased in the following order of chemical form： c2H4c2O4H2 〈 c2H4c2OH- 〈 c2H4c2O24-. With real seawater as the draw solution, low to moderate water fluxes （〈4 L. m- 2. h- 1 ） were observed. The divalent succinate anion was highly retained in the feed side despite differences in the succinic acid feed concentration at pH of approximately 6.90.

关键词： Forward osmosis Succinic acid pH Transport mechanism Seawater

Multiple sclerosis is at a checkpoint: advancing the program

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Neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon c.Smith Jessica L.Williams Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biological Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(cNS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage

Historical imaginaries, historic urban branding, and the local state in china: rejuvenation discourse, manufactured heritage and simulacrascapes

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Built Heritage 2023年第1期7卷 76-87页

作者： Andrew Malcolm law School of Architecture Planning and LandscapeNewcastle UniversityNewcastleUK

This intervention examines the extant literature on historical imaginaries and historic urban branding in *** suggests that while research in this field has increasingly moved away from an economic(or an implicit neo-Marxist)model,there is still a lack of research on the role of broader cultural and state led discourses of nationalism in the construction of historic urban imaginaries and historic urban branding within chinese *** unpacking one nationalistic discourse a-narrative of rejuvenation-this article argues that more needs to be done to examine the role of these themes in the construction of historical imaginaries at the level of the local state(including related state networks of developers,retailers,tourist officials,town planners,architects,and designers).It is suggested that an analysis of these discourses and imaginaries is important if we are:1)to appreciate the role of these themes in the construction and/or the reconfiguration of existing or emerging historic brands within chinese cities;2)to comprehend the construction of'authorised heritage discourses,(AHDs)practices and materialities at the level of the local state;3)to understand the politics of the past(including the uses of history,memory,nostalgia,and heritage)at the level of the local state;4)to be aware of the way in which these themes inform the preservation,conservation,and/or the demolition of heritage space at the level of the local state;5)to recognise the manufacture of'heritage'or simulacrascapes within chinese cities.

关键词： rejuvenation historical urban imaginaries historical urban branding built heritage simulacrascapes

The dispersion of surface contaminants by Stokes drift in random waves

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Acta Oceanologica Sinica 2018年第7期37卷 55-61页

作者： HUANG Guoxing law Wing-Keung Adrian State Key Laboratory of coastal and Offshore Engineering Dalian University of Technology Dalian 116024 China State Key Laboratory of Hydrology Water Resources and Hydraulics Engineering Nanjing 210029 China School of civil and Environmental Engineering Nanyang Technological University Singapore 639798 Singapore

contaminants that are floating on the surface of the ocean are subjected to the action of random *** the literature,it has been asserted by researchers that the random wave action will lead to a dispersion mechanism through the induced Stokes drift,and that this dispersion mechanism may have the same order of significance comparable with the others means due to tidal currents and *** is investigated whether or not surface floating substances will disperse in the random wave environment due to the induced Stokes *** analytical derivation is first performed to obtain the drift velocity under the random *** the analysis,it is shown that the drift velocity is a time-independent value that does not possess any fluctuation given a specific wave energy ***,the random wave drift by itself should not have a dispersive effect on the surface floating *** were then conducted with small floating objects subjected to P-M spectral waves in a laboratory wave flume,and the experimental results reinforced the conclusion drawn.

关键词： dispersion surface contaminants random wave Stokes drift

Dispersion in oscillatory electro-osmotic flow through a parallel-plate channel with kinetic sorptive exchange at walls

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Journal of Hydrodynamics 2014年第3期26卷 363-373页

作者： SONG Jie 吴朝安 law Wing-Keung Adrian School of civil and Environmental Engineering Nanyang Technological University Department of Mechanical Engineering The University of Hong Kong

Dispersion in time-oscillatory electro-osmotic flows in a slit micro-channel under the effect of kinetic sorptive exchange at walls is theoretically investigated using the homogenization method. The two walls of the channel are considered to be made up of different materials, and therefore have different zeta potentials and sorption coefficients. A general expression for the Taylor dispersion coefficient under different zeta potentials as well as various sorption conditions at the walls is derived analytically. The dispersion coefficient is found to be dependent on the oscillation frequency, the Debye parameter, the species partition coefficient, the reaction kinetics and the ratio of the wall potentials. The results demonstrate that the presence of wall sorption tends to enhance the dispersion when the oscillation frequency is low, but the effect is negligible in high-frequency oscillatory flows. Moreover, it is found that the dispersion coefficient could be significantly changed by adjusting the relative wall potentials for low-frequency flows.

关键词： oscillatory electro-osmotic flows dispersion sorptive walls homogenization method