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Journal of Rare Earths 2024年第4期42卷 775-782页

作者： Glaydson S.dos Reis Diana Pinto Sabrina F.lütke Eder c.lima luis F.O.Silva Irineu A.S.De Brum Guilherme l.Dotto Department of Forest Biomaterials and Technology Biomass Technology centre Swedish University of Agricultural SciencesUmeaE13Swedn Universidad De la costa Calle 58#55-66080002BarranquillaAtlanticoColombia Research Group on Adsorptive and catalytic Process Engineering(ENGEPAc) Federal University of Santa MariaAv.Roraima100079705900Santa MariaRSBrazil Institute of chemistry Federal University of Rio Grande do Sul90040060Porto AlegreBrazil

chitin powder and chitin-aerogel were prepared from shrimp wastes and used to uptake Y^(3+)from aqueous solutions and concentrate this rare earth element from phosphogypsum(PG).chitin aerogel displays a specific surface area of 945 m^(2)/g,while chitin powder is 3.6 m^(2)/g,which largely influences its adsorption *** the adsorption in synthetic solutions,the effect of pH on Y^(3+)removal is strong for chitin powder *** contrast,no big pH influence was detected for chitin *** interactions and chelation can highlight the proposed mechanism of Y^(3+)on chitin adsorbents for the powder and ***,in addition to these interactions,pore filling/pore diffusion is the main mechanism of Y^(3+)removal in the chitin *** aerogel is efficient in concentrating 8 times the Y^(3+)from PG,a very complex *** complex chitin aerogel-Y^(3+)can be a secondary source of rare earth elements for other applications.

关键词： Rare earths Sustainable material chitin powder chitin porous aerogel Yttrium adsorption and recovery

cD4^(+)T cells produce IFN-I to license cDc1s for induction of cytotoxic T-cell activity in human tumors

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cellular & Molecular Immunology 2024年第4期21卷 374-392页

作者： Xin lei Daniël c.de Groot Marij J.P.Welters Tom de Wit Ellen Schrama Hans van Eenennaam Saskia J.Santegoets Timo Oosenbrug Annemarthe van der Veen Joris l.Vos charlotte l.Zuur Noel F.c.c.de Miranda Heinz Jacobs Sjoerd H.van der Burg Jannie Borst Yanling Xiao Department of Immunology Leiden University Medical CenterLeidenThe Netherlands Oncode Institute Leiden University Medical CenterLeidenThe Netherlands Department of Tumor Biology and Immunology The Netherlands Cancer InstituteAmsterdamThe Netherlands Department of Medical Oncology Oncode InstituteLeiden University Medical CenterLeidenThe Netherlands IMMIOS B.V. OssThe Netherlands Division of Medical Oncology The Netherlands Cancer InstituteAmsterdamThe Netherlands Department of Otorhinolaryngology leiden University Medical center LeidenThe Netherlands Department of Pathology Leiden University Medical CenterLeidenThe Netherlands

cD4^(+)T cells can"help"or"license" conventional type 1 dendritic cells(cDc1s)to induce cD8^(+)cytotoxic T lymphocyte(cTl)anticancer responses,as proven in mouse *** recently identified cDc1s with a transcriptomic imprint of cD4^(+)T-cell help,specifically in T-cell-infiltrated human cancers,and these cells were associated with a good prognosis and response to PD-1-targeting ***,we delineate the mechanism of cDc1 licensing by cD4^(+)T cells in *** cD4^(+)T cells produce IFNβvia the STING pathway,which promotes MHc-I antigen(cross-)presentation by cDc1s and thereby improves their ability to induce cTl anticancer *** cooperation with cD40 ligand(l),IFNβalso optimizes the costimulatory and other functions of cDc1s required for cTl response ***-I-producing cD4^(+)T cells are present in diverse T-cell-infiltrated cancers and likely deliver“help”signals to cTls locally,according to their transcriptomic profile and colocalization with“helped/licensed”cDcs and tumor-reactive cD8^(+)T *** agreement with this scenario,the presence of IFN-I-producing cD4^(+)T cells in the TME is associated with overall survival and the response to PD-1 checkpoint blockade in cancer patients.

关键词： cD4^(+)T-cell help cDc1 licensing IFN-I signaling cD40 costimulation (cross-)presentation cTl priming Tumor control

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巴西油气勘探开发历程:从陆上到超深水

石油勘探与开发 2024年第4期51卷 796-806页

作者： ANJOS Sylvia M c SOMBRA cristiano l SPADINI Adali R 巴西国家石油公司里约热内卢20231-030巴西

21世纪以来,随着桑托斯盆地深水盐下获得一系列重大油气发现,巴西东部海域成为全球深水油气勘探与生产的热点区域。通过全面回顾巴西油气勘探开发历程,系统阐述了从陆上到海域、从浅水到深水—超深水直至盐下勘探的探索实践、战略转变... 详细信息

21世纪以来,随着桑托斯盆地深水盐下获得一系列重大油气发现,巴西东部海域成为全球深水油气勘探与生产的热点区域。通过全面回顾巴西油气勘探开发历程,系统阐述了从陆上到海域、从浅水到深水—超深水直至盐下勘探的探索实践、战略转变、重大突破和关键理论技术。巴西国家石油公司(简称巴西国油)自1953年成立以后的15年间,在陆上古生界克拉通盆地和断陷盆地进行了勘探,并于断块和三角洲砂体圈闭获得了一些中小型油气发现。20世纪70年代,应用重力流沉积模式和高质量三维地震等勘探新技术,在坎波斯盆地浅水中发现Namorado和Enchova等油田,随后深水盐上勘探获得突破,成功发现Marlim、Roncador等大型油田。21世纪初,通过盐下含油气系统、碳酸盐岩成储成藏模式和核磁共振测井等理论技术攻关,推动桑托斯盆地下白垩统湖相碳酸盐岩陆续获得Tupi(lula)、Buzios、Mero等世界级超深水盐下大油田的系列重大发现。在复杂的深水作业环境下,油气开发工程面临巨大挑战,巴西国油通过启动深水研发计划(PROcAP),开发并实施窄压力窗口控压钻井、加压钻井液帽钻井、多段智能完井、水下采油及浮式生产平台开发和流动保障等关键技术,显著提升了钻完井、油气田开发和输运的效率及安全性。此外,在浮式采储卸油系统建产规模受限的情况下,推进全球最大规模的cO_(2)捕集、驱油利用与埋存工程(ccUS-EOR),有效减少温室气体排放并提高了原油采收率。上述理论技术的发展和应用,也为全球深水油气勘探开发提供了宝贵经验。未来巴西油气勘探将继续聚焦深水盐下碳酸盐岩和盐上浊积岩,并在古生界天然气等勘探领域持续寻求新的发现,同时通过技术创新和战略合作,促进巴西石油天然气行业的可持续发展。

关键词：巴西深水盐下勘探坎波斯盆地桑托斯盆地浊积岩湖相碳酸盐岩深水开发流动保障

Spatial analysis of Dengue through the reproduction numbers relating to socioeconomic features:case studies on two Brazilian urban centers

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Infectious Disease Modelling 2024年第1期9卷 142-157页

作者： Ana T.c.Silva Rejane c.Dorn lívia R.Tomás leonardo B.l.Santos lacita M.Skalinski Suani T.R.Pinho Departamento de Física Universidade Estadual de Feira de SantanaAv.Transnordestinas/n.Novo HorizonteFeira de Santana44036-900BABrazil Instituto de Física Universidade Federal da BahiaRua Barão de Jeremoabo s/nCampus Universitário de OndinaSalvador40170-115BABrazil centro Nacional de Monitoramento e Alertas de Desastres Naturais(cEMADEN) Estrada Dr.Altino Bondensan500São Josédos Campos12247-016SPBrazil Universidade Estadual de Santa cruz Campus Soane Nazaréde AndradeRodovia Jorge AmadoKm 16SalobrinhoIlhéus45662-900BABrazil Instituto de Saúde coletiva Universidade Federal da BahiaR.Basílio da Gamas/n-CanelaSalvador40110-140BABrazil Instituto Nacional de ciência e Tecnologia-Sistemas complexos Virtual InstitutionBrazil

The study of the propagation of infectious diseases in urban centers finds a close connection with their population's social characteristics and *** work performs a spatial analysis of dengue cases in urban centers based on the basic reproduction numbers,R0,and incidence by planning areas(PAs),as well as their correlations with the Human Development Index(HDI)and the number of *** analyzed dengue epidemics in 2002 at two Brazilian urban centers,Belo Horizonte(BH)and Rio de Janeiro(RJ),using PAs as spatial *** results reveal heterogeneous spatial scenarios for both cities,with very weak correlations between R0 and both the number of trips and the HDI;in BH,the values of R0 show a less spatial heterogeneous pattern than in *** BH,there are moderate correlations between incidence and both the number of trips and the HDI;meanwhile,they weakly correlate for ***,the absence of strong correlations between the considered measures indicates that the transmission process should be treated considering the city as a whole.

关键词： Dengue Mathematical mode lBasic reproduction number Urban mobility Urban indices

Why Sustainable Porous carbon Should be Further Explored as Radar-Absorbing Material? A comparative Study with Different Nanostructured carbons

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Journal of Renewable Materials 2024年第10期12卷 1639-1659页

作者： Alan F.N.Boss Manuella G.c.Munhoz Gisele Amaral-labat Rodrigo G.A.lima leonardo I.Medeiros Nila c.F.l.Medeiros Beatriz c.S.Fonseca Flavia l.Braghiroli Guilherme F.B.lenz e Silva Department of Metallurgical and Materials Engineering University of de São PauloAvenida Mello MoraesCidade UniversitáriaSão PauloSP 05508-030Brazil coordination of Applied Research and Technological Development National Institute for Space ResearchAvenida dos AstronautasJardim da GranjaSão Josédos CamposSP 12227-010Brazil Department of Exact and Technological Sciences Santa Cruz State UniversityRodovia Jorge Amadokm16IlhéusBA 45662900Brazil Institut de recherche sur les forêts Universitédu Québec en Abitibi-TémiscamingueRouyn-Noranda445 Bd de l’UniversitéRouyn-NorandaQC J9X 5E4Canada

Radar Absorbing Materials(RAM)are a class of composites that can attenuate incident electromagnetic waves to avoid radar *** carbon allotropes that have the potential to be used as RAM are either carbon nano-tubes(cNTs),graphene,carbon black(cB)and ultimately,sustainable porous carbon(SPc).Here,black wattle bark waste(following tannin extraction)was used as a sustainable source to produce SPc made from biomass *** was characterized and used as aﬁller for a silicone rubber matrix to produce aﬂexible *** elec-tromagnetic performance of this composite was compared with composites made with commercial cB and cNT through reﬂection loss(Rl),where-10 dB is equivalent to 90%of *** composites were evaluated in single-layer,double-layer,and as radar absorbing structures(RAS)with the aim of improving their effective absorption bandwidth(EAB)performances and a reduction in *** cNT composite presented a Rl of-26.85 dB at 10.89 GHz and an EAB of 2.6 GHz with a 1.9 mm thickness,while the double-layer structures using cNT and SPc provided a Rl of-19.74 dB at 10.75 GHz and an EAB of 2.51 ***,the double-layer structures are~42%cheaper than the composite using only cNT since less material is ***,the largest EAB was achieved with a RAS using SPc,reaching~2.8 GHz and a Rl of-49.09 dB at 10.4 ***,SPc made of black wattle bark waste can be a competitive,alternative material for use as RAM and RAS since it is cheaper,sustainable,and suitable for daily life uses such as absorbers for anechoic chambers,sensors,and elec-tromagnetic interference shields for electronics,wallets,vehicles,and others.

关键词： Microwave absorption material tannin waste dielectric constant carbon composite reﬂectivity

Multiple sclerosis is at a checkpoint: advancing the program

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Neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon c.Smith Jessica l.Williams Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biological Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(cNS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage

In vivo measurement of NADH fluorescence lifetime in skeletal muscle via -ber-coupled time-correlated single photon counting

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Journal of Innovative Optical Health Sciences 2024年第1期17卷 121-134页

作者： Kathryn M.Priest Jacob V.Schluns Nathania Nischal colton l.Gattis Jeffrey c.Wolchok Timothy J.Muldoon Department of Biomedical Engineering University of Arkansas FayettevilleARUSA

Nicotinamide adenine dinucleotide(NADH)is a cofactor that serves to shuttle electrons during metabolic processes such as glycolysis,the tricarboxylic acid cycle,and oxidative phosphorylation(OXPHOS).NADH is autofluorescent,and itsfluorescence lifetime can be used to infer metabolic dynamics in living ***-coupled time-correlated single photon counting(TcSPc)equipped with an implantable needle probe can be used to measure NADH lifetime in vivo,enabling investigation of changing metabolic demand during muscle contraction or tissue *** study illustrates a proof of concept for point-based,minimally-invasive NADHfluorescence lifetime measurement in *** muscle loss(VMl)injuries were created in the left tibialis anterior(TA)muscle of male Sprague Dawley *** lifetime measurements were collected before,during,and after a 30 s tetanic contraction in the injured and uninjured TA muscles,which was subsequently-t to a biexponential decay model to yield a metric of NADH utilization(cytoplasmic vs protein-bound NADH,the A11/A22 ratio).On average,this ratio was higher during and after contraction in uninjured muscle compared to muscle at rest,suggesting higher levels of free NADH in contracting and recovering muscle,indicating increased rates of *** injured muscle,this ratio was higher than uninjured muscle overall but decreased over time,which is consistent with current knowledge of inflammatory response to injury,suggesting tissue regeneration has *** data suggest that-ber-coupled TcSPc has the potential to measure changes in NADH binding in vivo in a minimally invasive manner that requires further investigation.

关键词： Glycolysis oxidative phosphorylation energy metabolism volumetric muscle loss

Uncovering the hierarchical clusters in the heat-affected zone of an electron beam weldedα/βtitanium alloy joint

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Journal of Materials Science & Technology 2024年第7期174卷 120-132页

作者： c.Xu X.H.Shao H.J.Yang M.lv H.Q.liu X.l.Ma Shenyang National laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China Suzhou laboratory Suzhou 215028China Department of Mechanical Engineering Kyushu UniversityFukuoka 819-0395Japan Bay Area center for Electron Microscopy Songshan Lake Materials LaboratoryDongguan 523808China

Using high-resolution transmission Kikuchi diffraction(TKD)and transmission electron microscopy(TEM),we examined the hierarchical clusters that form in situ in the heat-affected zone(HAZ),which are com-monly referred to as“ghost”structures,of bimodal titanium alloy Ti-5Al-2Sn-2Zr-4Mo-4cr(wt%,Tc17).The ghost structures are enriched with Al elements but poor in Mo and cr compared to the surroundingβ*** results show that the ghost structure in middle-HAZ mainly consists ofα_(l)laths with a high-angle grain boundary,which exhibits the classic Burgers orientation relationship(BOR)with the host matrix,while it encircles theα_(P)grains in *** the ghost structure is evidenced to form via in-complete martensitic *** results further confirm that the ghost structure is composed ofαl and tinyβ_(l)laths with BOR,with the former being enriched with Al and poor with cr and Mo,while the latter is the ***,twoα_(l)variant clusters with a check-mark morphology are fre-quently observed viewed along[0001]_(αl)//[110]_(βl)directions,which are dominated by the crystallographic and geometrical relationships betweenαandβ*** on the microstructural characterization,it is hypothesized that the ghost structure is transformed from the initialα_(P)phase,due to the coupling ef-fect of high thermal stress(which induces the formation of a large number of dislocations)and element diffusion caused by sudden temperature increase and plunge cooling in the HAZ during the welding pro-cess.

关键词： Tc17 titanium alloy Electron beam welding(EBW) The ghost structure Transmission Kikuchi diffraction(TKD) Transmission electron microscopy(TEM)

输尿管结石:低剂量cT扫描方案应用于STONE评分为中-高度怀疑结石的急诊科病人

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国际医学放射学杂志 2016年第6期 677-677页

作者： c.l.moore B.Daniels D.Singh S.luty G.Gunabushanam M.Ghita 赵璐 Department of Emergency Medicine Yale University School of Medicine

摘要目的确定低剂量cT扫描方案是否能够有效地帮助鉴别出急诊科中-高度怀疑结石并需要90 d内泌尿外科进行干预的病人。方法本研究经机构伦理委员会批准,签署

关键词：输尿管结石泌尿外科 STONE 低剂量急诊科扫描方案病人 cT

Empirical model for fusion cross sections of ca-induced reactions

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chinese Physics c 2024年第3期48卷 126-132页

作者： Reddi Rani.l N.Sowmya K.N Sridhar H c.Manjunatha M.M.Armstrong Arasu Department of Physics St.Joseph's College(Autonomous)Affiliated to Bharathidasan UniversityTiruchirappalli620002TNIndia Department of Physics Govt.First.Grade CollegeChikkaballapur-562101KarnatakaIndia Department of Physics Govt.First.Grade CollegeMalur-563160KarnatakaIndia Department of Physics Govt.First.Grade CollegeDevanahalli-562110KarnatakaIndia

A new empirical formula for the astrophysical S-factor has been suggested as a function of the coulomb interaction parameter,center of mass energy,and barrier *** 22 fusion reactions with ^(40,48)ca as projectiles were considered for different targets,leading to compound nuclei with atomic and mass numbers varying between 40≤Z≤≤Z≤112 and 88≤A≤27888≤A≤278,*** fusion cross-sections have been estimated using the geometric factor,the Gamow-Sommerfield factor,and the empirical formula for the *** study's findings showed better agreement with those of available experiments when compared to Wong's *** present work leads to a smaller standard deviation value than Wong's formula when used to correlate the experimental data of calcium-induced fusion ***'s formula provides a good approximation of fusion cross-sections when the center of mass energy is below the fusion barrier when compared to above the fusion barrier.

关键词： fusion cross-sections Wong formula Gamow-Sommerfield-factor Geometric-factor S-factor