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Information Processing in Agriculture 2022年第4期9卷 533-546页

作者： Subha M.Roy c.M.Pareek Rajendra Machavaram c.k.mukherjee Agricultural and Food Engineering Department Indian Institute of Technology KharagpurKharagpur 721302West BengalIndia

Artificial aeration system for aquaculture ponds becomes essential to meet the oxygen requirement posed by the aquatic *** performance of an aerator is generally mea-sured in terms of standard aeration efficiency(SAE),which is significantly affected by the different geometric and dynamic parameters of the ***,to enhance the aer-ation performance of an aerator,these parameters need to be *** the present study,a perforated pooled circular stepped cascade(PPcSc)aerator was developed,and the geometric and dynamic parameters of the developed aerator were optimized using the hybrid ANN-PSO technique for maximizing its aeration *** geometric parameters include consecutive step width ratio(W_(i-1)/W_(i))and the perforation diameter to the bottom-most radius ratio(d/R_(b)),whereas the dynamic parameter includes the water flow rate(Q).A 3–6-1 ANN model coupled with particle swarm optimization(PSO)approach was used to obtain the optimum values of geometric and dynamic parameters correspond-ing to the maximum *** optimal values of the consecutive step width ratio(W_(i-1)/W_(i)),the perforation diameter to the bottom-most radius ratio(d/R_(b)),and the water flow rate(Q)for maximizing the SAE were found to be 1.15,0.0027 and 0.0167 m^(3)/s,*** cross-validation results showed a deviation of 3.07%between the predicted and experimen-tal SAE values,thus confirming the adequacy of the proposed hybrid ANN-PSO technique.

关键词： Aquaculture Artificial neural network(ANN) Particle swarm optimization(PSO) Perforated pooled circular stepped cascade(PPcSc)aerator Standard aeration efficiency(SAE)

Status and prospects for symmetric organic redox flow batteries

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Journal of Energy chemistry 2025年第1期100卷 125-143页

作者： Md Al Raihan c.Adam Dyker Department of chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. This review explores the growing field of symmetric organic redox flow batteries(ORFBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORFBs involve a single bipolar species for both electrodes. This review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. This should guide new research directions and advance the development of practical symmetric ORFBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

Acquired sensorineural hearing loss,oxidative stress,and microRNAs

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Neural Regeneration Research 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez Ru c.Guo Division of Otolaryngology–Head&Neck Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Neck Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada Faculty of Medicine–The University of British columbia VancouverBCCanada

Hearing loss is the third leading cause of human ***-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health ***-induced,ototoxic,and idiopathic sudden sensorineural are other less common types of acquired hearing *** etiology of these conditions is complex and multi-fa ctorial involving an interplay of genetic and environmental *** stress has recently been proposed as a likely linking cause in most types of acquired sensorineural hearing *** non-coding RNA sequences known as microRNAs(miRNAs)have increasingly been shown to play a role in cellular hypoxia and oxidative stress responses including promoting an apoptotic *** hair cell death is a central histopathological finding in sensorineural hearing *** these cells do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDLINE,Web of Science core collection,and *** databases over the period August 1,2018 to July 31,2023 were searched with"hearing loss,""hypoxamiRs,""hypoxia,""microRNAs,""ischemia,"and"oxidative stress"text words for English language primary study publications or registered clinical *** red clinical trials known to the senior author we re also assessed.A total of 222studies were thus *** excluding duplicates,editorials,retra ctions,secondary research studies,and non-English language articles,39 primary studies and clinical trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subject journal articles and 8 registered clinical trial database entries which form the basis of this narrative *** miR-34a and miR-29b levels increase with age in *** miRNAs were demonstrated in human neuroblastoma and murine cochlear cell lines to target Sirtuin 1/peroxisome proliferato r-activated receptor gamma coactivator-1-alpha(SIRT1/P Gc-1α),SIRT

关键词： hearing loss hypoxia microRNAs oxidative stress sensorineural

Inflammasome links traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease

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Neural Regeneration Research 2025年第6期20卷 1644-1664页

作者： Gabriela Seplovich Yazan Bouchi Juan Pablo de Rivero Vaccari Jennifer c.Munoz Pareja Andrew Reisner Laura Blackwell Yehia Mechref kevin k.Wang J.Adrian Tyndall Binu Tharakan Firas kobeissy Department of Surgery Morehouse School of MedicineAtlantaGAUSA Department of Neurobiology Center for NeurotraumaMultiomics&Biomarkers(CNMB)Neuroscience InstituteMorehouse School of MedicineAtlantaGAUSA Department of Neurological Surgery and the Miami Project to cure Paralysis University of Miami Miller School of MedicineMiamiFLUSA Division of Pediatric critical care Department of PediatricsUniversity of Miami Miller School of MedicineMiamiFLUSA Department of Pediatrics Emory UniversityAtlantaGAUSA Department of Neurosurgery Children’s Healthcare of AtlantaAtlantaGAUSA Department of chemistry and Biochemistry Texas Tech UniversityLubbockTXUSA Morehouse School of Medicine AtlantaGAUSA

Traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease are three distinct neurological disorders that share common pathophysiological mechanisms involving neuroinflammation. One sequela of neuroinflammation includes the pathologic hyperphosphorylation of tau protein, an endogenous microtubule-associated protein that protects the integrity of neuronal cytoskeletons. Tau hyperphosphorylation results in protein misfolding and subsequent accumulation of tau tangles forming neurotoxic aggregates. These misfolded proteins are characteristic of traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease and can lead to downstream neuroinflammatory processes, including assembly and activation of the inflammasome complex. Inflammasomes refer to a family of multimeric protein units that, upon activation, release a cascade of signaling molecules resulting in caspase-induced cell death and inflammation mediated by the release of interleukin-1β cytokine. One specific inflammasome, the NOD-like receptor protein 3, has been proposed to be a key regulator of tau phosphorylation where it has been shown that prolonged NOD-like receptor protein 3 activation acts as a causal factor in pathological tau accumulation and spreading. This review begins by describing the epidemiology and pathophysiology of traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease. Next, we highlight neuroinflammation as an overriding theme and discuss the role of the NOD-like receptor protein 3 inflammasome in the formation of tau deposits and how such tauopathic entities spread throughout the brain. We then propose a novel framework linking traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease as inflammasomedependent pathologies that exist along a temporal continuum. Finally, we discuss potential therapeutic targets that may intercept this pathway and ultimately minimize long-term neurological decline.

关键词： Alzheimer's disease caspase-1 chronic traumatic encephalopathy inflammasomes neurodegeneration neuroinflammation NLRP1 NLRP3 pyroptosis tauopathy traumatic brain injury

MHD graphene-polydimethylsiloxane Maxwell nanofluid flow in a squeezing channel with thermal radiation effects

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Applied Mathematics and Mechanics(English Edition) 2019年第9期40卷 1269-1284页

作者： G.c.SHIT S.mukherjee Department of Mathematics Jadavpur University

The magnetohydrodynamic (MHD) graphene-polydimethylsiloxane (PDMS) nanofluid flow between two squeezing parallel plates in the presence of thermal radiation effects is investigated. The energy efficiency of the system via the Bejan number is studied extensively. The governing partial differential equations are converted by using the similarity transformations into a set of coupled ordinary differential equations. The set of these converted equations is solved by using the differential transform method (DTM). The entropy generation in terms of the Bejan number, the coefficient of skin-friction, and the heat transfer rate is furthermore investigated under the effects of various physical parameters of interest. The present study shows that the Bejan number, the velocity and thermal profiles, and the rate of heat transfer decrease with a rise in the Deborah number De while the skin-friction coefficient increases. It is also observed that the entropy generation due to frictional forces is higher than that due to thermal effects. Thus, the study bears the potential application in powder technology as well as in biomedical engineering.

关键词： graphene-polydimethylsiloxane (PDMS) Maxwell fluid differential transform method (DTM) thermal radiation Bejan number

Biological Significance of [^(14)c]Phenol Accumulation in Different Organs of a Murrel, channa punctatus, and the common carp, cyprinus carpio

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Biomedical and Environmental Sciences 1990年第3期3卷 337-342页

作者： DILIP mukherjee DILIP mukherjee SHELLEY BHATTAcHARYA VINOD kUMAR JAIDEEP MOITRA Environmental Toxicology Laboratory Department of Zoology Visva-Bharati University Santiniketan 761235 India and Department of Zoology University of kalyani kalyani. 741235 India

Phenol, a ubiquitous component of industrial effluents, is a common pollutant of water resources and a serious threat to *** present work demonstrates that a significant amount of phenol is retained by various tissues of the common *** *** the snake-headed *** *** rate of [^(14)c] phenol accumulation was higher in the carp than in the *** is suggested that retention of phenol in the brain and ovary may seriously afiect the reproductive potential of the fish. 1990 Academic ***.

关键词： cyprinus carpio Biological Significance of c]Phenol Accumulation in Different Organs of a Murrel channa punctatus

Multiple sclerosis is at a checkpoint: advancing the program

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Neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon c.Smith Jessica L.Williams Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biological Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(cNS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage

Temperatures and Winds over Tropical Middle Atmosphere during Two contrasting Summer Monsoons, 1975 and 1979

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Advances in Atmospheric Sciences 1989年第3期6卷 325-334页

作者： B.k.mukherjee c.P.kulkarni k.Indira k.k.Dani Indian Institute of Tropical Meteorology Pune-411005IndiaIndian Institute of Tropical MeteorologyPune-411005IndiaIndian Institute of Tropical MeteorologyPune-411005IndiaIndian Institute of Tropical MeteorologyPune-411005India

Using the monthly geopotential heights and winds for 700 and 200 hPa for India during July and August, and the weekly M-100 Soviet rocketsonde temperature and wind data for Thumba (8.5 ° N, 76.9 ° E) during the last week of June and the first week of September for the two contrasting summer monsoon years 1975 (a very strong monsoon year) and 1979 (a very weak monsoon year), a study has been made to examine the mean circulation features of the troposphere over India, and the structures of the temperatures and the winds of the middle atmosphere over Thumba. The study suggested that the axis of the monsoon trough (AMT) at 700 hPa shifted southward in 1975 and northward towards the foothills of the Himalayas in 1979, from its normal position. Superimposed on the low-pressure area (AMT) at 700 hPa, a well-defined divergence was noticed at 200 hPa over the northern India in *** mean temperatures at 25,50 and 60 km (middle atmosphere) over Thumba were cooler in 1975 than in 1979. While a cooling trend in 1975 and warming trend in 1979 were observed at 25 and 50 km, a reversed picture was noticed at 60 km. There was a weak easterly / westerly (weak westerly phase) zonal wind in 1975 and a strong easterly zonal wind in 1979. A phase reversal of the zonal wind was observed at 50 km. A tentative physical mechanism was offered, in terms of upward propagation of the two equatorially trapped planetary waves i.e. the kelvin and the mixed Rossby-gravity waves, to explain the occurrence of the two spells of strong warmings in the mesosphere in 1975.

关键词： over In and 1979 Temperatures and Winds over Tropical Middle Atmosphere during Two contrasting Summer Monsoons

Si/Si c-based DD hetero-structure IMPATTs as MM-wave power-source:a generalized large-signal analysis

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Journal of Semiconductors 2015年第6期36卷 58-63页

作者： Moumita mukherjee P.R.Tripathy S.P.Pati centre for MM-wave Semiconductor Devices and Systems (cMSDS) DRDO Hi-Tech college of Engineering Former Professor of Sambalpur University

A full-scale, self-consistent, non-linear, large-signal model of double-drift hetero-structure IMPATT diode with general doping profile is derived. This newly developed model, for the first time, has been used to analyze the large-signal characteristics of hexagonal Sic-based double-drift IMPATT diode. considering the fabrication feasibility, the authors have studied the large-signal characteristics of Si/Sic-based hetero-structure devices. Under small-voltage modulation （~ 2%, i.e. small-signal conditions） results are in good agreement with calculations done using a linearised small-signal model. The large-signal values of the diode＇s negative conductance （5 × 106 S/m2）, susceptance （10.4 × 107 S/m2）, average breakdown voltage （207.6 V）, and power generating efficiency （15%, RF power： 25.0 W at 94 GHz） are obtained as a function of oscillation amplitude （50% of Dc breakdown voltage） for a fixed average current density. The large-signal calculations exhibit power and efficiency saturation for large-signal （〉 50%） voltage modulation and thereafter decrease gradually with further increasing voltage-modulation. This generalized large-signal formulation is applicable for all types of IMPATT structures with distributed and narrow avalanche zones. The simulator is made more realistic by incorporating the space-charge effects, realistic field and temperature dependent material parameters in Si and Sic. The electric field snap-shots and the large-signal impedance and admittance of the diode with current excitation are expressed in closed loop form. This study will act as a guide for researchers to fabricate a high-power Si/Sic-based IMPATT for possible application in high-power MM-wave communication systems.

关键词： Si/Sic hetero-structure double drift diode full-scale large-signal modelling high-power parasiticeffects noise-analysis

Statistical Modeling Studies of Iron Recovery from Red Mud Using Thermal Plasma

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Plasma Science and Technology 2013年第5期15卷 459-464页

作者： Swagat S. RATH Archana PANY k. JAYASANkAR Ajit k. MITRA c. SATISH kUMAR Partha S. mukherjee Barada k. MISHRA Institute of Minerals and Materials Technology (cSIR) Vedanta Alumina Limited Lanjigarh

Optimization studies of plasma smelting of red mud were carried out. Reduction of the dried red mud fines was done in an extended arc plasma reactor to recover the pig iron. Lime grit and low ash metallurgical （LAM） coke were used as the flux and reductant, respectively. 2level factorial design was used to study the influence of all parameters on the responses. Response surface modeling was done with the data obtained from statistically designed experiments. Metal recovery at optimum parameters was found to be 79.52%.

关键词： plasma response surface modeling red mud design of experiments optimiza-tion