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Status and prospects for symmetric organic redox flow batteries

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journal of Energy chemistry 2025年第1期100卷 125-143页

作者： Md Al Raihan c.Adam Dyker Department of chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. This review explores the growing field of symmetric organic redox flow batteries(ORFBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORFBs involve a single bipolar species for both electrodes. This review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. This should guide new research directions and advance the development of practical symmetric ORFBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

Radio spectral index from NVSS and TGSS

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Research in Astronomy and Astrophysics 2019年第7期19卷 59-66页

作者： prabhakar Tiwari National Astronomical Observatories Chinese Academy of Sciences

I extract the radio spectral index,α,from 541 195 common sources observed in the 150 MHz TIFR GMRT Sky Survey(TGSS) and the 1.4 GHz NRAO VLA Sky Survey(NVSS).This large common source catalog covers about 80% of the *** flux density limits in these surveys are such that the observed galaxies are presumably hosts of active galactic nuclei(AGNs).I confirm the steepening of αwith increasing flux density for this large sample and provide a parametric fit between α and flux ***,I divide the data into low flux(LF) and high flux(HF) density samples with roughly equal numbers of *** LF sample contains all galaxies below 100 m jy TGSS and 20 m jy NVSS flux density and the HF sample is all galaxies above 100 m jy TGSS and 20 m jy NVSS.I observe an increase in α with source size(TGSS measured),saturating for large sizes to 0.89 ± 0.22 and 0.76 ± 0.21 for the LF and HF sources,respectively.I discuss the observed results and possible physical mechanisms to explain observedα dependence with source size for LF and HF samples.

关键词： galaxies:high-redshift galaxies:active galactic nuclei

A review:Advances in microbial remediation of trichloroethylene (TcE)

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journal of Environmental Sciences 2010年第1期22卷 116-126页

作者： prabhakar Pant Sudhakar Pant Applied Research center Florida International University Department of Biology St. Xavier's College

Research works in the recent past have revealed three major biodegradation processes leading to the degradation of trichloroethylene. Reductive dechlorination is an anaerobic process in which chlorinated ethenes are used as electron acceptors. On the other hand, cometabolism requires oxygen for enzymatic degradation of chlorinated ethenes, which however yields no benefit for the bacteria involved. The third process is direct oxidation under aerobic conditions whereby chlorinated ethenes are directly used as electron donors by microorganisms. This review presented the current research trend in understanding biodegradation mechanisms with regard to their field applications. All the techniques used are evaluated, with the focus being on various factors that influence the process and the outcome.

关键词： biodegradation trichloroethylene reductive dechlorination cometabolism direct oxidation

A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair

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Neural Regeneration Research 2025年第1期20卷 291-304页

作者： Simeon c.Daeschler Katelyn j.W.So Konstantin Feinberg Marina Manoraj jenny cheung jennifer Zhang Kaveh Mirmoeini jPaul Santerre Tessa Gordon Gregory HBorschel SickKids Research Institute Neuroscience and Mental Health ProgramTorontoONCanada Institute of Biomaterials and Biomedical Engineering University of TorontoTorontoONCanada Indiana University School of Medicine IndianapolisINUSA Division of Plastic and Reconstructive Surgery the Hospital for Sick ChildrenTorontoONCanada Translational Biology and Engineering Program Ted Rogers Centre for Heart ResearchInstitute of Biomedical EngineeringFaculty of DentistryUniversity of TorontoTorontoONCanada

Axonal regeneration following surgical nerve repair is slow and often incomplete,resulting in poor functional recovery which sometimes contributes to lifelong ***,there are no FDA-approved therapies available to promote nerve *** accelerates axonal regeneration,but systemic side effects presently outweigh its potential benefits for peripheral nerve *** authors describe herein a biodegradable polyurethane-based drug delivery system for the sustained local release of tacrolimus at the nerve repair site,with suitable properties for scalable production and clinical application,aiming to promote nerve regeneration and functional recovery with minimal systemic drug *** is encapsulated into co-axially electrospun polycarbonate-urethane nanofibers to generate an implantable nerve wrap that releases therapeutic doses of bioactive tacrolimus over 31 *** and drug loading are adjustable for applications in small and large caliber nerves,and the wrap degrades within 120 days into biocompatible *** released from the nerve wrap promotes axon elongation in vitro and accelerates nerve regeneration and functional recovery in preclinical nerve repair models while off-target systemic drug exposure is reduced by 80%compared with systemic *** its surgical suitability and preclinical efficacy and safety,this system may provide a readily translatable approach to support axonal regeneration and recovery in patients undergoing nerve surgery.

关键词： biodegradable local drug delivery nerve injury nerve regeneration nerve wrap tacrolimus

URjA:A sustainable energy distribution and trade model for smart grids

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Blockchain(Research and Applications) 2022年第4期3卷 21-32页

作者： Anjana prabhakar Tricha Anjali International Institute of Information Technology Bangalore560100India Actyv Bangalore560034India

Energy has always been one of the fundamental elements in the growth of human *** is crucial that we improve our energy management due to the ever-growing imbalance in *** new wave in the energy sector is characterized by the three D's of decarbonization,decentralization,and *** a sustainable life,it is necessary that energy is tapped from alternative sources that are renewable to leave a minimal carbon *** integrate different sources with the main power grid,we require two-way communication among *** makes it indispensable that consumers are empowered to protect their privacy and make them the sole owners of their data.A good access control scheme would ensure security of data,and an efficient trading platform would ensure judicious use of the ***,we propose a framework URjA with an access control scheme and an energy trading platform based on blockchain for a smart *** locally available renewable sources of energy are connected to the grid such that demand-supply is managed effectively without loss of efficiency and privacy.A customized consensus scheme based on trust ensures a quick operation in real-time.

关键词： Access control Blockchain Smart grid Smart contracts Sustainability Energy trade

Acquired sensorineural hearing loss,oxidative stress,and microRNAs

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Neural Regeneration Research 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez Ru c.Guo Division of Otolaryngology–Head&Neck Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Neck Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada Faculty of Medicine–The University of British columbia VancouverBCCanada

Hearing loss is the third leading cause of human ***-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health ***-induced,ototoxic,and idiopathic sudden sensorineural are other less common types of acquired hearing *** etiology of these conditions is complex and multi-fa ctorial involving an interplay of genetic and environmental *** stress has recently been proposed as a likely linking cause in most types of acquired sensorineural hearing *** non-coding RNA sequences known as microRNAs(miRNAs)have increasingly been shown to play a role in cellular hypoxia and oxidative stress responses including promoting an apoptotic *** hair cell death is a central histopathological finding in sensorineural hearing *** these cells do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDLINE,Web of Science core collection,and *** databases over the period August 1,2018 to july 31,2023 were searched with"hearing loss,""hypoxamiRs,""hypoxia,""microRNAs,""ischemia,"and"oxidative stress"text words for English language primary study publications or registered clinical *** red clinical trials known to the senior author we re also assessed.A total of 222studies were thus *** excluding duplicates,editorials,retra ctions,secondary research studies,and non-English language articles,39 primary studies and clinical trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subject journal articles and 8 registered clinical trial database entries which form the basis of this narrative *** miR-34a and miR-29b levels increase with age in *** miRNAs were demonstrated in human neuroblastoma and murine cochlear cell lines to target Sirtuin 1/peroxisome proliferato r-activated receptor gamma coactivator-1-alpha(SIRT1/P Gc-1α),SIRT

关键词： hearing loss hypoxia microRNAs oxidative stress sensorineural

Mechanism of Action of Natural Products Used in the Treatment of Diabetes Mellitus

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chinese journal of Integrative Medicine 2011年第8期17卷 563-574页

作者： Pranav Kumar prabhakar Mukesh Doble Department of Biotechnology Indian Institute of Technology Madras

Diabetes mellitus（DM） is a metabolic disorder caused by insufficient or inefficient insulin secretary response and it is characterized by increased blood glucose levels（hyperglycemia）.DM is a heterogonous group of *** is the main energy source for the body,and in the case of DM,management of glucose becomes *** are three key defects in the onset of hyperglycemia in DM,namely increased hepatic glucose production,diminished insulin secretion, and impaired insulin *** drugs treat diabetes by improving insulin sensitivity,increasing insulin production and/or decreasing the amount of glucose in *** article provides a comprehensive review of the mode of action of most popular hypoglycemic herbs,such as ginseng,bitter melon,fenugreek,banaba, Gymnema sylvestre and coptis *** herbs act by increasing insulin secretion,enhancing glucose uptake by adipose and skeletal muscle tissues,inhibiting intestinal glucose absorption and inhibiting hepatic glucose *** evidence from animals and humans consistently supports the therapeutic effect of these phytomedicines,multicenter large-scale clinical trials have not been conducted to evaluate the safety and efficacy of these herbal medicines and their interaction with conventional drugs when administered simultaneously.

关键词： hyperglycemia medicinal plants ginseng bitter melon fenugreek banaba

Apples to oranges:environmentally derived,dynamic regulation of serotonin neuron subpopulations in adulthood?

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Neural Regeneration Research 2025年第9期20卷 2596-2597页

作者： christopher j.O’connell Matthew j.Robson Department of Genetics College of MedicineHarvard UniversityBostonMAUSA james L.Winkle college of Pharmacy Division of Pharmaceutical SciencesUniversity of CincinnatiCincinnatiOHUSA Neuroscience Graduate Program College of MedicineUniversity of CincinnatiCincinnatiOHUSA

Traumatic brain injury(TBI)is a public health problem with an undue economic burden that impacts nearly every age,ethnic,and gender group across the globe(capizzi et al.,2020).TBIs are often sustained during a dynamic range of exposures to energetic environmental forces and as such outcomes are typically heterogeneous regarding severity and pathology(capizzi et al.,2020).

关键词： sustained orange dynamic

Multiple sclerosis is at a checkpoint: advancing the program

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Neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon c.Smith jessica L.Williams Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biological Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(cNS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage