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国外水产 1985年第1期 41-44页

作者： c.j.grant 崔建章

金斯顿港集结着一种刺网渔业.它的捕捞对象是加勒比海常见的小型沿岸上层鱼类,其中三种属于鲱科,一种是鲹科鱼类.这些鱼类的地理分布和最大体长分别为:

关键词：刺网渔获率网目尺寸体长青鳞鱼鱼类水生动物刺网选择性

Diabetic peripheral neuropathy and neuromodulation techniques:a systematic review of progress and prospects

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Neural Regeneration Research 2025年第8期20卷 2218-2230页

作者： Rahul Mittal Keelin McKenna grant Keith Evan McKenna joana R.N.Lemos jeenu Mittal Khemraj Hirani Diabetes Research Institute University of Miami Miller School of MedicineMiamiFLUSA Department of Otolaryngology University of Miami Miller School of MedicineMiamiFLUSA Herbert Wertheim college of Medicine Florida International UniversityMiamiFLUSA School of Medicine and Public Health University of WisconsinMadisonWIUSA

Neuromodulation for diabetic peripheral neuropathy represents a significant area of interest in the management of chronic pain associated with this *** peripheral neuropathy,a common complication of diabetes,is characterized by nerve damage due to high blood sugar levels that lead to symptoms,such as pain,tingling,and numbness,primarily in the hands and *** aim of this systematic review was to evaluate the efficacy of neuromodulatory techniques as potential therapeutic interventions for patients with diabetic peripheral neuropathy,while also examining recent developments in this *** investigation encompassed an array of neuromodulation methods,including frequency rhythmic electrical modulated systems,dorsal root ganglion stimulation,and spinal cord *** systematic review suggests that neuromodulatory techniques may be useful in the treatment of diabetic peripheral *** the advantages of these treatments will enable physicians and other healthcare providers to offer additional options for patients with symptoms refractory to standard pharmacologic *** these efforts,we may improve quality of life and increase functional capacity in patients suffering from complications related to diabetic neuropathy.

关键词： diabetes mellitus diabetic peripheral neuropathy neuromodulation neurostimulation therapy non-pharmacological treatment pain management

competition for food in 2 populations of a wild-caught fish

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current Zoology 2018年第5期64卷 615-622页

作者： Pierre j.c. cHUARD grant E. BROWN james W.A. grant Research School of Biology The Australian National University Canberra ACT 0200 Australia Departmentof Biology Concordia University 7141 Sherbrooke Street West Montreal Quebec Canada H4B 1R6

Aggressive behavior when competing for resources is expected to increase as the ratio of competitors-to-resource ratio （cRR） units increases. Females are expected to be more aggressive than males when competing for food when body size is more strongly related to reproductive suc- cess in females than in males, whereas aggression is predicted to decrease under high ambient predation risk by natural selection. Under the risk allocation model, however, individuals under high ambient predation risk are expected to be more aggressive, and forage more in the absence of imminent risk than their low risk counterparts. An interaction between adult sex ratio （i.e., adult males/females）, ambient predation risk （high vs. low）, and sex on intrasexual competition for mates in Trinidadian guppies Poecilia reticulata has been shown. The interaction suggested an increase in aggression rates as cRR increased, except for males from the high predation population. To compare the patterns of competition for food versus mates, we replicated this study by using food patches. We allowed 4 male or 4 female guppies from high and low predation populations to com- pete for 5, 3, or 1 food patches. The foraging rate was higher in a high rather than low ambient pre- dation risk population. Surprisingly, cRR, sex, and population of origin had no effect on aggression rates. Despite other environmental differences between the 2 populations, the effect of ambient predation risk may be a likely explanation for differences in foraging rates. These results highlight the importance for individuals to secure food despite the cost of competition and predation.

关键词： aggression competitor-to-resource ratio foraging Poecifia reticulata population differences predation risk sex

Status and prospects for symmetric organic redox flow batteries

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journal of Energy chemistry 2025年第1期100卷 125-143页

作者： Md Al Raihan c.Adam Dyker Department of chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. This review explores the growing field of symmetric organic redox flow batteries(ORFBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORFBs involve a single bipolar species for both electrodes. This review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. This should guide new research directions and advance the development of practical symmetric ORFBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair

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Neural Regeneration Research 2025年第1期20卷 291-304页

作者： Simeon c.Daeschler Katelyn j.W.So Konstantin Feinberg Marina Manoraj jenny cheung jennifer Zhang Kaveh Mirmoeini jPaul Santerre Tessa Gordon Gregory HBorschel SickKids Research Institute Neuroscience and Mental Health ProgramTorontoONCanada Institute of Biomaterials and Biomedical Engineering University of TorontoTorontoONCanada Indiana University School of Medicine IndianapolisINUSA Division of Plastic and Reconstructive Surgery the Hospital for Sick ChildrenTorontoONCanada Translational Biology and Engineering Program Ted Rogers Centre for Heart ResearchInstitute of Biomedical EngineeringFaculty of DentistryUniversity of TorontoTorontoONCanada

Axonal regeneration following surgical nerve repair is slow and often incomplete,resulting in poor functional recovery which sometimes contributes to lifelong ***,there are no FDA-approved therapies available to promote nerve *** accelerates axonal regeneration,but systemic side effects presently outweigh its potential benefits for peripheral nerve *** authors describe herein a biodegradable polyurethane-based drug delivery system for the sustained local release of tacrolimus at the nerve repair site,with suitable properties for scalable production and clinical application,aiming to promote nerve regeneration and functional recovery with minimal systemic drug *** is encapsulated into co-axially electrospun polycarbonate-urethane nanofibers to generate an implantable nerve wrap that releases therapeutic doses of bioactive tacrolimus over 31 *** and drug loading are adjustable for applications in small and large caliber nerves,and the wrap degrades within 120 days into biocompatible *** released from the nerve wrap promotes axon elongation in vitro and accelerates nerve regeneration and functional recovery in preclinical nerve repair models while off-target systemic drug exposure is reduced by 80%compared with systemic *** its surgical suitability and preclinical efficacy and safety,this system may provide a readily translatable approach to support axonal regeneration and recovery in patients undergoing nerve surgery.

关键词： biodegradable local drug delivery nerve injury nerve regeneration nerve wrap tacrolimus

Local predation risk shapes spatial and foraging neophobia patterns in Trinidadian guppies

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current Zoology 2016年第5期62卷 457-462页

作者： chris K. ELVIDGE Pierre j.c. cHUARD grant E. BROWN Department of Biology Concordia University 7141 Sherbrooke St. West Montreal QC H4B 1R6 Canada

The ＂dangerous niche＂ hypothesis posits that neophobia functions to reduce the cost of habitat use among animals exposed to unknown risks. For example, more dangerous foraging or higher competi- tion may lead to increased spatial neophobia. Likewise, elevated ambient predation threats have been shown to induce phenotypically plastic neophobic predator avoidance. In both cases, neophobia is argued to reduce the cost of living associated with ecological uncertainty. Here, we test the hypothesis that ambient predation shapes both neophobic predator avoidance and spatial and foraging neophobia in Trinidadian guppies. Guppies were exposed to a novel foraging arena paired with a known cue （conspecific alarm cue）, a novel cue （lemon odor）, or a stream water control in three streams differing in ambient predation risk. We demonstrate that guppies from a high-predation-risk stream exhibited risk-averse foraging patterns regardless of the chemical stimulus presented （high spatial neophobia） and that those from a low-predation-risk stream were only risk-averse when the foraging arenas were paired with conspecific alarm cue （lower spatial neophobia）. Those tested in the intermediate- predation-risk stream were consistently intermediate to the high-risk vs. low-risk populations. Our study suggests that ambient predation risk shapes both neophobic predator avoidance and space-use pat- terns and that neophobia may function as a ＂generalized＂ response to ecological uncertainty.

关键词： phenotypic plasticity predator recognition foraging predator recognition predator-prey interactions Trinidadian guppies.

Acquired sensorineural hearing loss,oxidative stress,and microRNAs

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Neural Regeneration Research 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez Ru c.Guo Division of Otolaryngology–Head&Neck Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Neck Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada Faculty of Medicine–The University of British columbia VancouverBCCanada

Hearing loss is the third leading cause of human ***-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health ***-induced,ototoxic,and idiopathic sudden sensorineural are other less common types of acquired hearing *** etiology of these conditions is complex and multi-fa ctorial involving an interplay of genetic and environmental *** stress has recently been proposed as a likely linking cause in most types of acquired sensorineural hearing *** non-coding RNA sequences known as microRNAs(miRNAs)have increasingly been shown to play a role in cellular hypoxia and oxidative stress responses including promoting an apoptotic *** hair cell death is a central histopathological finding in sensorineural hearing *** these cells do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDLINE,Web of Science core collection,and *** databases over the period August 1,2018 to july 31,2023 were searched with"hearing loss,""hypoxamiRs,""hypoxia,""microRNAs,""ischemia,"and"oxidative stress"text words for English language primary study publications or registered clinical *** red clinical trials known to the senior author we re also assessed.A total of 222studies were thus *** excluding duplicates,editorials,retra ctions,secondary research studies,and non-English language articles,39 primary studies and clinical trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subject journal articles and 8 registered clinical trial database entries which form the basis of this narrative *** miR-34a and miR-29b levels increase with age in *** miRNAs were demonstrated in human neuroblastoma and murine cochlear cell lines to target Sirtuin 1/peroxisome proliferato r-activated receptor gamma coactivator-1-alpha(SIRT1/P Gc-1α),SIRT

关键词： hearing loss hypoxia microRNAs oxidative stress sensorineural

Olfaction and reaction: The role of olfactory and hypothalamic investment in the antipredator responses to chemical alarm cues by northern redbelly dace

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current Zoology 2023年第6期69卷 738-746页

作者： Brendan j.joyce grant E.Brown Department of Biology Concordia UniversityMontrealQuebecCanada

Neuroplasticity enables teleosts to promote or downregulate the growth of their brains *** compensate for the effects of predation pressure,teleosts may alter their brain morphology and behavioral responses to mitigate its impact on individual ***-predation environ-ments often promote specific patterns of brain growth and produce bolder and more proactive *** to the expense of maintaining neural tissue,relative size indicates the regions most relied *** northern redbelly dace chrosomus eos,as little as 2 weeks of elevated predation pressure,resulted in increased investment in their olfactory bulbs and optic tecta,while the imposition of captivity produced smaller,less symmetric *** together,these results suggest that an individual could potentially become better able to detect a threat,and simultaneously less inclined to react to it,making the impact of either change in isolation is difficult to ***,we compared interindividual variation in gross brain morphology,risk-taking tactics in a novel arena(shy-bold personality),and responding to olfactory cues(proactive/reac-tive stress-coping style).We hypothesized that olfactory investment would positively correlate with response intensity to predator cue concen-tration and respond across a wider range of cue concentrations,while hypothalamus size would correlate with shyness and *** to heightened risk produced more bold/proactive individuals,with larger olfactory bulbs and smaller ***,the direction of the correlation between hypothalamus size and behavior varied by treatment,and olfactory investment only corresponded with response intensity amongst proactive *** findings illustrate the potential pitfalls of relating gross brain morphology to complex behavior and suggest that stress-coping style is a relevant consideration in future studies.

关键词： boldness brainmorphology neuroplasticity predation proactivity stress-coping style

A Strong Stability Preserving Analysis for Explicit Multistage Two-Derivative Time-Stepping Schemes Based on Taylor Series conditions

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communications on Applied Mathematics and computation 2019年第1期1卷 21-59页

作者： Zachary grant Sigal Gottlieb David c.Seal Department of computational and Applied Mathematics Oak Ridge National LaboratoryOak RidgeUSA Department of Mathematics University of Massachusetts DartmouthDartmouthUSA Department of Mathematics U.S.Naval AcademyAnnapolisUSA

High-order strong stability preserving(SSP)time discretizations are often needed to ensure the nonlinear(and sometimes non-inner-product)strong stability properties of spatial discretizations specially designed for the solution of hyperbolic ***-derivative time-stepping methods have recently been increasingly used for evolving hyperbolic PDEs,and the strong stability properties of these methods are of *** our prior work we explored time discretizations that preserve the strong stability properties of spatial discretizations coupled with forward Euler and a second-derivative ***,many spatial discretizations do not satisfy strong stability properties when coupled with this second-derivative formulation,but rather with a more natural Taylor series *** this work we demonstrate sufficient conditions for an explicit two-derivative multistage method to preserve the strong stability properties of spatial discretizations in a forward Euler and Taylor series *** call these strong stability preserving Taylor series(SSP-TS)*** also prove that the maximal order of SSP-TS methods is p=6,and define an optimization procedure that allows us to find such SSP *** types of these methods are presented and their efficiency ***,these methods are tested on several PDEs to demonstrate the benefit of SSP-TS methods,the need for the SSP property,and the sharpness of the SSP time-step in many cases.

关键词： Strong stability preserving Taylor series.Hyperbolic conservation laws Two derivative Runge Kutta

Apples to oranges:environmentally derived,dynamic regulation of serotonin neuron subpopulations in adulthood?

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Neural Regeneration Research 2025年第9期20卷 2596-2597页

作者： christopher j.O’connell Matthew j.Robson Department of Genetics College of MedicineHarvard UniversityBostonMAUSA james L.Winkle college of Pharmacy Division of Pharmaceutical SciencesUniversity of CincinnatiCincinnatiOHUSA Neuroscience Graduate Program College of MedicineUniversity of CincinnatiCincinnatiOHUSA

Traumatic brain injury(TBI)is a public health problem with an undue economic burden that impacts nearly every age,ethnic,and gender group across the globe(capizzi et al.,2020).TBIs are often sustained during a dynamic range of exposures to energetic environmental forces and as such outcomes are typically heterogeneous regarding severity and pathology(capizzi et al.,2020).

关键词： sustained orange dynamic