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减少肝脏横波弹性成像中的测量次数:临床实践中影响肝纤维化评估中测量次数和可靠性的因素

中国化学会第十九届全国化学热力学和热分析学术会议

作者： Y.Zhou c.fang T.Yamaguchi K.Yoshida Y.fang F.Zhu H.Liu Key Laboratory of comprehensive and Highly Efficient Utilization of Salt Lake Resources Qinghai Institute of Salt LakesChinese Academy of Sciences Key Laboratory of Salt Lake Resources chemistry of Qinghai Province Department of chemistry Faculty of ScienceFukuoka University

Numerous investigations have led to the consensus that aqueous borate solutions are more complicated than other aqueous inorganic salt *** instance,the polyborate distribution equilibria and their relevant interactions in aqueous borate solution are determined by temperature,pH,boron concentration,counter ions,***,as typical incongruent dissolved compounds,aqueous borate solutions(such as magnesium borate and lithium borate) show some extremely abnormal supersaturated features,which adds to the difficulties for the solid-liquid phase equilibrium prediction and borate mass ***,what’s the chemical substantial for the widely observed and controversial "Salification by diluting" and "Salification by heating" rules? Which is a long pending problem in salt lake *** the present presentation,works we have done in this filed by Raman spectra and calculations(thermodynamic,DFT,cPMD) are retrieved *** attempts from structural aspect with X-ray diffractions and empirical potential structure refinement(EPSR) are ***,some applications based on those results are introduced *** hydration induces ployborate depolymerization or polymerization,which is one of the determining factors for polybrate distribution and seriously affects the solid-liquid phase *** borate brine can crystallize by mixing with some fresh water or diluted brine,which has become one of the key methods for borate mass production from bittern in the salt *** borate anions hydration,ion association is also critical for understanding the supersaturation phenomena of aqueous borate *** such as Li and Mg with tight hydrated sphere,they are difficult in forming direct contact ion pairs(the crystal nucleus for crystallisation).Break the stability of the hydration sphere of those cations by heating or pressurising is a good solution for speeding supersaturated aqueous borate solution crystallisation.

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国际医学放射学杂志 2018年第4期 480-481页

作者： c.fang O.S.Jaffer G.T.Yusuf E.Konstantatou D.J.Quinlan K.Agarwal 何博 Department of Radiology King’s College Hospital

目的确定利用点横波弹性成像(p SWE)无创评估肝纤维化所需的最小测量次数,并验证使用可靠性指标如四分位间距(IQR)与中位数比值是否会影响诊断效能。材料与方法纳入232名受试者,并经pSWE获得10个肝横波速度(SWV)测量值。计算前2～9个测... 详细信息

目的确定利用点横波弹性成像(p SWE)无创评估肝纤维化所需的最小测量次数,并验证使用可靠性指标如四分位间距(IQR)与中位数比值是否会影响诊断效能。材料与方法纳入232名受试者,并经pSWE获得10个肝横波速度(SWV)测量值。计算前2～9个测量的中位数与整体10个测量值之间的组内相关系数(Icc);确定Icc>0.95且与整体10个测量的最小测量次数。利用受试者操作特征曲线下面积,比较最小测量数量和10次测量在鉴别肝显著性纤维化(Ishak分期3)和严重肝纤维化/肝硬化(Ishak分期5)中的诊断效能。比较指标间可靠性能(分别为IQR-中位数比值≤30%,IQR-中位数比值>30%)。结果相比10次测量值,至少需要测量6次SWV,使得肝显著纤维化的曲线下面积(受试者操作特征曲线下面积,0.828∶0.839;P=0.487)和严重纤维化/肝硬化(0.953∶0.969;P=0.145)的差异无统计学意义。以6次测量值的中位数进行评价仅会导致少数与组织学结果不相符[9/232(3.9%)]。当采用10次测量值进行pSWE评价时,与较低可靠性的测量结果 [显著性纤维化(26/82,31.7%)和严重纤维化/肝硬化(8/82,9.8%)]相比,较高可靠性的测量结果不一致百分比[显著纤维化(22/150,14.7%)和严重纤维化/肝硬化(3/150,2.0%)]较低。肝显著纤维化是低可靠性测量中的独立预测因子(风险比2.22;P=0.020)。结论利用pSWE评估肝脏纤维化可以采用较少的SWV测量次数(中位数6∶10),且与较低可靠性测量值相比,测量次数对诊断准确度影响较小。

关键词：弹性成像测量值中位数肝纤维化测量次数

Identification of ScAR markers for screening alfalfa salt tolerance cultivars

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Identification of SCAR markers for screening alfalfa salt to...

On Hamiltonian Property of cayley Digraphs

第七届草食动物营养国际学术研讨会

作者： W.B.Ren~1 c.fang~1 H.Q.Guo~2 J.G.Han~(*1) ~1 Institute of Grassland Science china Agricultural University Beijing 10094 P.R.china 2 Inner Mongolia Agricultural University Huhhot 010018 china

＜正＞In order to screen salt-tolerant cultivars of crops,adequate and efficient selection methods have to be *** study reported the development of ScAR markers linked to quantitative traits loci controlling salt tolerance in *** ScAR primers were created by sequencing a single 1.4-kb RAPD fragment,which was regularly identified in salt tolerant alfalfa （Medicago sativa L.） *** then its relationship with QTL loci controlling salt tolerance was verified by F2 populations constructed by crossing salt tolerant plants with salt sensitive plants. Finally a total of 17 elite cultivars,which represents a variety of salt tolerance in three stages （germinating stage,seedling stage and mature plant stage） were *** showed that ScAR,as a dominant marker,was regularly amplified from salt-tolerant individuals with the recombination value of 3.0%.More than 40% of individuals from salt tolerant cultivars showed the presence of salt-specific ScAR marker,while less than 20% plants from salt sensitive plants showed the ScAR *** our knowledge,this is the first report in alfalfa with a ScAR marker associated with salt tolerance and would be useful to screen large numbers of breeding materials and varieties for their ability related to salt tolerance.

关键词： Medicago sativa salt tolerance ScAR marker

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Acta Mathematicae Applicatae Sinica 2024年第2期40卷 547-556页

作者： fang DUAN Qiong-xiang HUANG School of Mathematics Science Xinjiang Normal UniversityUrumqi 830017China college of Mathematics and Systems Science Xinjiang UniversityUrumqi 830017China

Let G be a finite group generated by S and c(G,S) the cayley digraphs of G with connection set *** this paper,we give some sufficient conditions for the existence of hamiltonian circuit in c(G,S),where G=Zm×H is a semiproduct of Zmby a subgroup H of *** particular,if m is a prime,then the cayley digraph of G has a hamiltonian circuit unless G=Zm×*** addition,we introduce a new digraph operation,called φ-semiproduct of Γ1by Γ2and denoted by Γ1×Γ_φΓ2,in terms of mapping φ:V(Γ2)→{1,-1}.Furthermore we prove that c(Zm,{a})×_φ c(H,S) is also a cayley digraph if φ is a homomorphism from H to{1,-1} ≤ Zm~*,which produces some classes of cayley digraphs that have hamiltonian circuits.

关键词： cayley digraphs hamiltonian circuit external semidirect product

卒中和短暂性脑缺血发作患者的卒中预防指南美国心脏协会/美国卒中协会为医疗卫生专业人员制定的指南

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国际脑血管病杂志 2014年第11期22卷 805-841页

作者： Walter N.Kernan Bruce Ovbiagele Henry R.Black Dawn M.Bravata Marc I.chimowitz Michael D.Ezekowitz Margaret c.fang Marc Fisher Karen L.Furie 洪道俊黄招君李小兵周美鸿吴成斯王博卢艺吴裕臣代表美国心脏协会卒中委员会、心血管和卒中护理委员会、临床心脏病学委员会以及周围血管病委员会南昌大学第一附属医院神经内科 330006

本更新版指南旨在为缺血性卒中或短暂性脑缺血发作存活者的卒中预防提供全面和及时的循证推荐.本指南适用于所有为上述患者提供二级预防的临床医生.这些循证推荐包括危险因素的控制、血管闭塞的干预、心源性栓塞的抗栓治疗以及非心源性... 详细信息

本更新版指南旨在为缺血性卒中或短暂性脑缺血发作存活者的卒中预防提供全面和及时的循证推荐.本指南适用于所有为上述患者提供二级预防的临床医生.这些循证推荐包括危险因素的控制、血管闭塞的干预、心源性栓塞的抗栓治疗以及非心源性栓塞性卒中的抗血小板治疗.还对各种特殊情况下复发性卒中的预防提供了推荐意见,包括主动脉弓粥样硬化、动脉夹层分离、卵圆孔未闭、高同型半胱氨酸血症、高凝状态、抗心磷脂抗体综合征、镰状细胞病、脑静脉窦血栓形成以及妊娠.此外,还有专门的章节对颅内出血后抗栓和抗凝治疗的应用以及指南的实施进行了讨论.

关键词：美国心脏协会声明心房颤动颈动脉狭窄高血压缺血短暂性脑缺血发作预防卒中

Fe-N-c core-shell catalysts with single low-spin Fe(Ⅱ)-N_(4)species for oxygen reduction reaction and high-performance proton exchange membrane fuel cells

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Journal of Energy chemistry 2024年第6期93卷 538-546,I0013页

作者： Yan Wan Linhui Yu Bingxin Yang caihong Li chen fang Wei Guo fang-Xing Xiao Yangming Lin Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials Xiamen Institute of Rare Earth MaterialsHaixi InstituteChinese Academy of SciencesXiamen 361021FujianChina cAS Key Laboratory of Urban Pollutant conversion Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021FujianChina Fujian Institute of Research on the Structure of Matter Chinese Academy of SciencesFuzhou 350002FujianChina college of Materials Science and Engineering Fuzhou UniversityNew CampusMinhou 350108FujianChina college of chemistry and Materials Science Fujian Normal UniversityFuzhou 350117FujianChina

Fe-N-doped carbon materials(Fe-N-c)are promising candidates for oxygen reduction reaction(ORR)relative to Pt-based catalysts in proton exchange membrane fuel cells(PEMFcs).However,the intrinsic contributions of Fe-N_(4)moiety with different chemical/spin states(e.g.D1,D2,D3)to ORR are unclear since various states coexist *** the present work,Fe-N-c core-shell nanocatalyst with single lowspin Fe(Ⅱ)-N_(4)species(D1)is synthesized and identified with ex-situ ultralow temperature Mossbauer spectroscopy(T=1.6 K)that could essentially differentiate various Fe-N_(4)states and invisible Fe-O *** quantifying with cO-pulse chemisorption,site density and turnover frequency of Fe-N-c catalysts reach 2.4×10^(-9)site g^(-1)and 23 e site~(-1)s^(-1)during the ORR,***-wave potential(0.915V_(RHE))of the Fe-N-c catalyst is more positive(approximately 54 mV)than that of Pt/***,we observe that the performance of PEMFcs on Fe-N-c almost achieves the 2025 target of the US Department of Energy by demonstrating a current density of 1.037 A cm^(-2)combined with the peak power density of 0,685 W cm^(-2),suggesting the critical role of Fe(Ⅱ)-N_(4)site(D1).After 500 h of running,PEMFcs still deliver a power density of 1.26 W cm^(-2)at 1.0 bar H_(2)-O_(2),An unexpected rate-determining step is figured out by isotopic labelling experiment and theoretical *** work not only offers valuable insights regarding the intrinsic contribution of Fe-N_(4)with a single spin state to alkaline/acidic ORR,but also provides great opportunities for developing high-performance stable PEMFcs.

关键词： Fuel cells Oxygen reduction reaction Non-platinum group metals(PGMs) Isotopic labelling Active site TOF

Performance of iron-air battery with iron nanoparticle-encapsulated c-N composite electrode

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Frontiers in Energy 2024年第1期18卷 42-53页

作者： can fang Xiangmei TANG Jiaoyan WANG Qingfeng YI School of chemistry and chemical Engineering Hunan University of Science and TechnologyXiangtan 411201China Hunan Provincial Key Laboratory of Advanced Materials for New Energy Storage and conversion Xiangtan 411201China

Highly efficient and stable iron electrodes are of great significant to the development of iron-air battery(IAB).In this paper,iron nanoparticle-encapsulated c–N composite(NanoFe@cN)was synthesized by pyrolysis using polyaniline as the c–N *** performance of the NanoFe@cN in different electrolytes(alkaline,neutral,and quasi-neutral)was investigated via cyclic voltammetry(cV).The IAB was assembled with NanoFe@cN as the anode and IrO_(2)+Pt/c as the *** effects of different discharging/charging current densities and electrolytes on the battery performance were also *** K_(2)SO_(4)electrolyte can effectively suppress the passivation of iron electrode,and the battery showed a good cycling stability during 180 charging/discharging *** to the pure nano-iron(NanoFe)battery,the NanoFe@cN battery has a more stable cycling stability either in KOH or NH_(4)cl+Kcl electrolyte.

关键词： energy storage and conversion metallic composites nanocomposites iron-air battery iron anode

Your personal choices in transportation and food are important for lowering carbon emissions

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Frontiers of Environmental Science & Engineering 2024年第6期18卷 27-32页

作者： Bruce Logan fang Zhang Wulin Yang Le Shi Institute of Energy and the Environment The Pennsylvania State UniversityUniversity ParkPA 16802USA School of Environment Tsinghua UniversityBeijing 100084China college of Environmental Sciences and Engineering Peking UniversityBeijing 100871China college of Environmental and Resource Sciences Zhejiang UniversityHangzhou 310058China

There is a global need to reduce greenhouse gas emissions to limit the extent of climate change.A better understanding of how our own activities and lifestyle influence our energy use and carbon emissions can help us enable changes in activities that can lead to reductions in carbon *** we discuss an approach based on examining carbon emissions from the perspective of the unit c,where 1 c is the cO_(2)from food a person would on average eat every *** approach shows that total cO_(2)emissions in china,normalized by the population,is 22.5 c while carbon emissions for a person in the US is 43.9 c.A better appreciation of our own energy use can be obtained by calculating carbon emissions from our own activities in units of c,for example for driving a car gasoline or electric vehicle a certain number of kilometers,using electricity for our homes,and eating different *** this information,we can see how our carbon emissions compare to national averages in different countries and make decisions that could lower our personal cO_(2)emissions.

关键词： carbon dioxide climate change Daily energy Greenhouse gas

Uniqueness on Difference Operators of Meromorphic Functions of Infinite Order

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Acta Mathematica Sinica,English Series 2024年第2期40卷 511-527页

作者： Hui LI Ming Liang fang Xiao YAO School of Science China University of Mining and TechnologyBeijing 100083P.R.China Institute of Mathematics Academy of Mathematics and System SciencesChinese Academy of SciencesBeijing 100190P.R.China School of Sciences Hangzhou Dianzi UniversityHangzhou 310012P.R.China School of Mathematical sciences and LPMc Nankai UniversityTianjin 300071P.R.China

We investigate the uniqueness problems of meromorphic functions and their difference operators by using a new *** is proved that if a non-constant meromorphic function f shares a non-zero constant and ∞ counting multiplicities with its difference operators Δcf(z) and Δ_(c)^(2)f(z), thenΔcf(z)≡Δ_(c)^(2)f(z).In particular,we give a difference analogue of a result of *** method has two distinct features:(ⅰ) It converts the relations between functions into the corresponding *** makes it possible to deal with the uniqueness problem by linear algebra and combinatorics.(ⅱ) It circumvents the obstacle of the difference logarithmic derivative lemma for meromorphic functions of infinite order,since this method does not depend on the growth of the ***,the idea in this paper can also be applied to the case for several variables.

关键词： Uniqueness meromorphic functions difference operators infinite order