检索结果-南通市图书馆

Immunomodulatory activity of polycaprolactone nanoparticles with calcium phosphate salts against Leishmania infantum infection

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2024年第8期14卷 359-368页

作者： Kübra Kelleci Adil Allahverdiyev Melahat Bağırova Murat Ihlamur EmrahŞefik Abamor Department of Bioengineering Yildiz Technical UniversityIstanbulTurkey V.Akhundov National Scientific Research Medical Prophylactic Institute BakuAzerbaijan Department of Electronics and Automation Biruni UniversityIstanbulTurkey

Objective:To prepare and characterize polycaprolactone(PcL)nanoparticles loaded with sonicator fragmented(SLA)and freeze-thaw Leishmania antigens(FTLA)and to investigate the in vitro immunogenicity of antigen-encapsulated nanoparticles with calcium phosphate ***:The water/oil/water binary emulsion solvent evaporation method was used to synthesize antigen-loaded PcL *** were characterized by scanning electron microscopy and zeta potential *** cytotoxicity in J774 macrophages in vitro was determined by MTT *** addition,the amount of nitric oxide and the level of cytokines produced by macrophages were determined by griess reaction and ELISA method,*** protective effect of the developed formulations was evaluated by determining the infection index percentage in macrophages infected with Leishmania ***:compared to the control group,SLA PcL and FTLA PcL nanoparticles with calcium phosphate adjuvant induced a 6-and 7-fold increase in nitric oxide,***,the vaccine formulations promoted the production of IFN-γand *** PcL and FTLA PcL nanoparticles combined with calcium phosphate adjuvant caused an approximately 13-and 11-fold reduction in infection index,respectively,compared to the control ***:The encapsulation of antigens obtained by both sonication and freeze-thawing into PcL nanoparticles and the formulations with calcium phosphate adjuvant show strong in vitro immune stimulating ***,PcL-based antigen delivery systems and calcium phosphate adjuvant are recommended as a potential vaccine candidate against leishmaniasis.

关键词： Leishmaniasis calcium phosphate Polycaprolactone Nanoparticle Antigen delivery system Adjuvant Vaccine design

chinese expert consensus on the clinical application of drugcoated balloon(2^(nd) Edition)

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of geriatric cardiology 2024年第2期21卷 135-152页

作者： The Expert Writing committee of the chinese Expert consensus on clinical Applications of Drug-coated Balloon(2^(nd)Edition) Jun-bo gE Yun-Dai cHEN 不详 Zhongshan Hospital Fudan University chinese PLA general Hospital

Percutaneous coronary interventions have progressed through the era of plain balloon dilation, bare-metal stent insertion to drug-eluting stent treatment, which has significantly reduced the acute occlusion and restenosis rates of target vessels and improved patient prognosis, making drug-eluting stents the mainstream interventional treatment for coronary artery disease. In recent years, drug-coated balloons(DcBs) have become a new treatment strategy for coronary artery disease, and the drugs used in the coating and the coating technology have progressed in the past years. Without permanent implant, a DcB delivers antiproliferative drugs rapidly and uniformly into the vessel wall via the excipient during a single balloon dilation. Many evidence suggests that DcB angioplasty is an effective measure for dealing with in-stent restenosis and de novo lesions in small coronary *** more clinical studies are published, new evidence is emerging for the use of DcB angioplasty in a wide range of coronary diseases, and the indications are expanding internationally. Based on the latest research from china and elsewhere, the Expert Writing committee of the chinese Expert consensus on clinical Applications of Drug-coated Balloon has updated the previous DcB consensus after evidence-based discussions and meetings in terms of adequate preparation of in-stent restenosis lesions, expansion of the indications for coronary de novo lesions, and precise guidance of DcB treatment by intravascular imaging and functional evaluation.

关键词： balloon drugs dealing

gluing Affine Vortices

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2024年第1期40卷 250-312页

作者： guang bo XU Department of Mathematics Rutgers UniversityHill Center-Busch Campus 110 Frelinghuysen RoadPiscatawayNJ 08854-8019USA

We provide an analytical construction of the gluing map for stable affine vortices over the upper half plane with the Lagrangian boundary *** result is a necessary ingredient in studies of the relation between gauged ... 详细信息

关键词： Affine vortices gauged linear sigma model adiabatic limit symplectic reduction

Effect of trigger system on experimental dispersion characteristics of active surface wave testing

在线全文

学校读者我要写书评

暂无评论

Earthquake Engineering and Engineering Vibration 2024年第2期23卷 311-318页

作者： Lin Shibin Jeramy c.Ashlock Zhu Liming Qin Zexiang Li bo Zhu Xingji Zhai changhai State Key Laboratory of Precision Blasting Jianghan UniversityWuhan 430056China Hubei Key Laboratory of Blasting Engineering Jianghan UniversityWuhan 430056China Department of civil Construction&Environmental EngineeringIowa State UniversityAmesIA 50010USA Wuhan Airport Road Development co. Ltd.Wuhan 430065China School of civil and Environmental Engineering Harbin Institute of TechnologyShenzhen 518055China Key Lab of Structures Dynamic Behavior and control of the Ministry of Education Harbin Institute of TechnologyHarbin 150090China Key Lab of Smart Prevention and Mitigation of civil Engineering Disaster of the Ministry of Industry and Information Technology Harbin Institute of TechnologyHarbin 150090China

A trigger system is typically employed in active seismic testing to trigger and synchronize multichannel surface wave data *** effect of the trigger system on the dispersion image of surface waves is empirically known to be negligible,however,theoretical explanation regarding the effect of the trigger system is *** study systematically examines the theory for surface wave dispersion analysis and proves that the effect of the trigger system on a dispersion image is negligible via a solid theoretical ***,based on the new theoretical explanation,an alternative method that uses only the relative phase difference between sensors to extract dispersion characteristics with better conceptual clarity is *** active surface wave testing cases are considered to validate the theory and *** results indicate that(1)an accurate trigger system is not necessary for surface wave data acquisition,and(2)it is unnecessary to assume that the impact point is the generation point of the surface waves for the experimental dispersion analysis.

关键词： site investigation surface waves data acquisition dispersion

cO_(2) capture by modified clinoptilolite and its regeneration performance

在线全文

学校读者我要写书评

暂无评论

International Journal of coal Science & Technology 2024年第2期11卷 81-90页

作者： bo Jiang bo Zhang Xuqin Duan Yi Xing School of Energy and Environmental Engineering University of Science and Technology BeijingBeijing 100083China Beijing Key Laboratory of Resource-Oriented Treatment of Industrial Pollutants University of Science and Technology BeijingBeijing 100083China YangQuan coal Industry(group)co.Ltd. Yangquan 045000China School of civil and Resource Engineering University of Science and Technology BeijingBeijing 100083China

This study focuses on cO_(2) capture by pressure swing adsorption(PSA),with modified clinoptilolite as the *** clinoptilolite is modified by roasting,by acid pickling,by a combination of acid pickling and roasting,and by ion *** by acid pickling-roasting and by ion exchange are found to give the highest cO_(2) adsorption capacities,of 730 mL/g and 876.7 mL/g,*** is found that regeneration of clinoptilolite by a combination of vacuum desorption and heating enables recovery of as much as 89%of its previous cO_(2) adsorption *** examine the cO_(2) adsorption capacity of clinoptilolite when applied to mixed gas,a simulated coking exhaust containing 12%cO_(2) and 4%O_(2) is used,and it is found that ion exchange modified clinoptilolite achieves a cO_(2) removal efficiency of 92.5%.A BET test reveals that acid pickling-roasting and Na^(+) modification enhance the porosity of clinoptilolite,thereby improving its adsorption *** work demonstrates the feasibility of applying modified clinoptilolite as an effective adsorbent for cOO_(2)capture,providing a promising tool for dealing with greenhouse gases.

关键词： clinoptilolite carbon dioxide capture Pressure swing adsorption(PSA)

Realizing high initial coulombic efficiency in manganese-based layered oxide cathodes for sodium-ion batteries via P2/O'3 biphasic structure optimization

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2024年第5期43卷 2093-2102页

作者： bo Peng Zi-Hao Zhou Ping Xuan Jie Xu Lian-bo Ma School of Materials Science and Engineering Anhui University ofTechnologyMa'anshan 243002China Anhui Product Quality Supervision&Inspection Research Institute Hefei 230051China

Mn-based layered oxides are among the most promising cathode materials for sodium-ion batteries owing to the advantages of abundance,environmenta friendliness,low cost and high specific capacity.P2 and O'3 are two representative structures of Mn-based layered ***,the P2 structure containing insufficien Na generally exhibits low initial charge capacity,while O'3structure with sufficient Na delivers high initial charge capacity but poor cycle *** study prepared a multitude of Na_(x)MnO_(2)(x=0.7,0.8,0.9)cathode materials with varying P2/O'3 ratios and further investigated their electrochemical *** optimized Na_(0.8)MnO_(2) comprising 69.9 wt%O'3 and 30.1 wt%P2 phase,exhibited relatively balanced specific capacity,coulombic efficiency and cycle ***,it achieved a high specific capacity of 128.9 mAh·g^(-1) with an initia coulombic efficiency of 98.2%in half-cell configuration The Na_(0.8)MnO_(2)//hard carbon full cell also achieved a high specific capacity of 126.7 mAh·g^(-1) with an initia coulombic efficiency of 98.9%.Moreover,the capacity fading mechanism was revealed by combining in-situ and ex-situ X-ray *** findings of this study provide theoretical guidance for further modification design of Mnbased layered cathodes.

关键词： Sodium-ion batteries cathode materials Mn-based layered oxides P2/0'3 composites

Nonlocal symmetries,soliton-cnoidal wave solution and soliton molecules to a(2+1)-dimensional modified KdV system

在线全文

学校读者我要写书评

暂无评论

communications in Theoretical Physics 2024年第4期76卷 14-21页

作者： Jianyong Wang bo Ren Department of Mathematics and Physics Quzhou UniversityQuzhou 324000China Department of Mathematics Zhejiang University of TechnologyHangzhou 310014China

A(2+1)-dimensional modified KdV(2DmKdV)system is considered from several ***,residue symmetry,a type of nonlocal symmetry,and the Bäcklund transformation are obtained via the truncated Painlevéexpansion ***,the residue symmetry is localized to a Lie point symmetry of a prolonged system,from which the finite transformation group is ***,the integrability of the 2DmKdV system is examined under the sense of consistent tanh expansion ***,explicit soliton-cnoidal wave solutions are ***,abundant patterns of soliton molecules are presented by imposing the velocity resonance condition on the multiple-soliton solution.

关键词： soliton-cnoidal wave solution nonlocal symmetry soliton molecule (2+1)-dimensional modified KdV system

catalysis by subsurface metal atoms in Al(001) through electron transfer

在线全文

学校读者我要写书评

暂无评论

National Science Review 2024年第4期11卷 12-13页

作者： bo Sun Ding Ma Beijing National Laboratory for Molecular Science New Cornerstone Science Laboratory College of Chemistry and Molecular Engineering Peking University

Heterogeneous catalysis plays a crucial role in the chemical industry, which has evolved from the investigation of chemisorption to an electronic structure[1]. Diverse strategies, such as alloying,doping, and confining, have been applied to enhance the catalytic properties of active sites through electronic modulation. The electron transfer between active sites and substrates profoundly influences catalytic activity [2].

关键词：

Evolution and governance of the Structure of Marine Economic Networks in china’s coastal Areas: Based on Sea-related A-share Listed companies

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

chinese geographical Science 2024年第5期34卷 899-916页

作者： LI bo cAO gai Key Research Base of Humanities and Social Sciences of Ministry of Education Institute of Marine Sustainable DevelopmentLiaoning Normal UniversityDalian 116029China School of Maritime Economics and Management Dalian Maritime UniversityDalian 116026China

Data on discrete,isolated attributes of the marine economy are often used in traditional marine economic ***,as the focus of urban research shifts from internal static attributes to external dynamic linkages,the importance of marine economic net-work research is beginning to *** construction of the marine economic network in china’s coastal areas is necessary to change the flow of land and sea resources and optimize regional marine economic *** data from headquarters and branches of sea-related A-share listed enterprises to construct the marine economic network in china,we use social network analysis(SNA)to discuss the characteristics of its evolution as of 2010,2015,and 2020 and its *** following results were obtained.1)In terms of topological characteristics,the scale of the marine economic network in china’s coastal areas has accelerated and expan-ded,and the connections have become increasingly close;thus,this development has complex network characteristics.2)In terms of spatial structure,the intensity of the connection fluctuates and does not form stable development support;the group structure gradually becomes clear,but the overall pattern is fragmented;there are spatial differences in marine economic agglomeration radiation;the radi-ation effect of the eastern marine economic circle is obvious;and the polarization effect of northern and southern marine economic circles is *** this basis,we construct a framework for the governance of a marine economic network with the market,the government,and industry as the three governing *** clarifying the driving factors and building objectives of marine economic network construction,this study aims to foster the high-quality development of china’s marine economy.

关键词： marine economic network sea-related A-share listed companies social network analysis(SNA) network governance china’s coastal areas