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Perfect Adaptation of General Nonlinear Systems

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Journal of Systems Science & complexity 2016年第1期29卷 61-73页

作者： su Wei The Key Laboratory of Systems and control Academy of Mathematics and Systems ScienceChinese Academy of Sciences

Perfect adaptation describes the ability of a biological system to restore its biological function precisely to the pre-perturbation level after being affected by the environmental ***,a biological system with perfect adaptation can be modelled as an input-output nonlinear system whose output,usually determining the biological function,is asymptotically stable under all input disturbances *** this paper,a quite general input-output mathematical model is employed and the 'functional' of biological function(FBF)- output Lyapunov function- is explored to investigate its perfect adaptation *** condition is established for the systems with FBF to achieve perfect *** a sufficient and necessary condition is obtained for the linear systems to possess an output Lyapunov ***,it is shown that the 'functional'of receptors activity exists in the perfect adaptation model of *** *** with the existing mathematical surveys on perfect adaptation,most of which are based on the standpoint of control theory,we first investigate this problem using ways of nonlinear systems analysis.

关键词： Output Lyapunov function perfect adaptation perturbed nonlinear systems

上海原油期货价格成为亚太地区基准价了吗?——基于有效性、主导性和独立性的三维视角研判

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经济问题 2025年第1期 57-69页

作者：苏鹏李梓莹郭庆然新疆大学经济与管理学院新疆乌鲁木齐830046 新疆大学新疆创新管理研究中心新疆乌鲁木齐830046

我国在石油等大宗商品价格形成的影响力严重缺失,因“亚洲溢价”问题长期承受较高的贸易成本,影响我国能源安全及经济稳定。由此应运而生的上海原油期货,以期扭转我国在全球石油贸易中的被动局面,发挥在亚太地区基准价的作用。为此,从... 详细信息

我国在石油等大宗商品价格形成的影响力严重缺失,因“亚洲溢价”问题长期承受较高的贸易成本,影响我国能源安全及经济稳定。由此应运而生的上海原油期货,以期扭转我国在全球石油贸易中的被动局面,发挥在亚太地区基准价的作用。为此,从有效性、主导性、独立性三维视角,采用时变参数向量自回归模型(TVP-VAR-DY)、分位数向量自回归模型(QVAR-DY)及网络分析等方法,系统地对上海原油期货价格成为亚太地区基准价的进程进行了研判。研究发现:上海原油期货价格发挥出了引导区域原油现货价格和规避市场风险的功能,具备有效性;上海原油期货价格在极高分位数水平下对亚太地区原油现货价格的影响具备优势,但其还未体现出主导性;上海原油期货价格作为信息发出者,具有较强惯性和抗风险能力,具备相对独立性。由此判断,上海原油期货已初步成长为具有区域影响力的原油期货,虽然对现货价格的主导性上与Brent和WTI尚有差距,但在价格走势上保有较强的区域独立性,对中国和整个亚太地区的供需能够予以及时、有效反馈,作为全球原油消费重地,亚太地区缺乏自身定价基准的局面正在改变。

关键词：上海原油期货亚太地区基准价区域影响力

Enhanced subacute ischemic stroke treatment via multistage drug delivery system design for combination therapy

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Science china chemistry 2025年

作者： Xihan Xu Juan-Juan Li Jiamin Li Hui-Yan Zhang Yilin Qi Bing-Sen Shi Tianqi Li Shan-Shan su Weitao Zhao chang chen Zhongying Gong Huiyu Liu Ke-Rang Wang Dong-Sheng Guo Xue Xue State Key Laboratory of Medicinal chemical Biology College of Pharmacy Nankai University college of chemistry State Key Laboratory of Elemento-Organic Chemistry Key Laboratory of Functional Polymer Materials (Ministry of Education) Frontiers Science Center for New Organic Matter Collaborative Innovation Center of Chemical Science and EngineeringNankai University college of chemistry and Materials Science State Key Laboratory of New Pharmaceutical Preparations and Excipients Key Laboratory of Medicinal Chemistry and Molecular Diagnosis (Ministry of Education) Key Laboratory of Chemical Biology of Hebei Province Hebei Research Center of the Basic Discipline of Synthetic Chemistry Hebei University Department of Neurology Tianjin First Central Hospital School of Medicine Nankai University Beijing Advanced Innovation center for Soft Matter Science and Engineering State Key Laboratory of Organic-Inorganic Composites Beijing Laboratory of Biomedical Materials Bionanomaterials & Translational Engineering Laboratory Beijing Key Laboratory of BioprocessBeijing University of Chemical Technology

The management of acute ischemic stroke remains challenging due to its abrupt onset and the narrow treatment window,resulting in high rates of disability and *** therapy for neuroprotection and neurorepair strategies provided new hopes for subacute stroke *** we designed a multistage nanodelivery system that matches the unique microenvironment of the subacute phase of stroke,which utilizes calixarene as a building block to effectively load the neuroprotective drug *** calixarene is designed with glycosidic linkages targeting the glucose transporter 1 (GLUT1)on the blood-brain barrier (BBB) and azo bonds that are responsive to hypoxic ***,the decomposed calixarene molecules themselves possess intrinsic bio-activation to modulate inflammatory responses,achieving a multistage therapeutic approach that transitions from targeting to release and finally to *** approach combines anti-inflammation and neuroprotection,providing a multi-level treatment *** system was validated in a rat model of permanent middle cerebral artery occlusion (pMcAO),demonstrating that intravenous administration of the nanodelivery system repairs brain damage and improves motor function 24 h post-pMcAO *** work offers a precise and integrative strategy for stroke patients missing the acute therapy window to improve functional recovery and enhance the effect of comprehensive treatment.

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论校本教研功能的三重属性

北京教育学院学报 2025年第1期39卷 47-53页

作者：苏君阳北京师范大学教育学部北京100875

校本教研是以校为本的一种特殊的教学研究活动。校本教研功能具有认识论、方法论与实践论三重属性:认识论属性功能是提升教师教学观念认识水平,方法论属性功能是提升教师研究意识与科研素养水平,实践论属性功能是提升教师课堂教学创新... 详细信息

校本教研是以校为本的一种特殊的教学研究活动。校本教研功能具有认识论、方法论与实践论三重属性:认识论属性功能是提升教师教学观念认识水平,方法论属性功能是提升教师研究意识与科研素养水平,实践论属性功能是提升教师课堂教学创新与改进能力。认识论属性功能是校本教研作用发挥的重要前提,方法论属性功能是校本教研作用得以更好发挥的可靠保障,实践论属性功能是校本教研作用发挥的根本指向与最终目的。

关键词：校本教研认识论方法论实践论

中国文化产品出口竞争力的测度及其影响因素的实证研究

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兔源支气管败血波氏杆菌荧光定量PcR检测方法的建立

当代经济 2025年第1期42卷 104-112页

作者：郑绪涛苏冉湖北经济学院经贸学院

首先,运用贸易竞争指数、显性比较优势指数等指标测算中国文化产品的出口竞争力水平,研究结果发现,中国文化产品的出口竞争力在逐渐提高,但不同类别文化产品的出口竞争力差异较大,中国文化产品"物的类别"具有较高的出口竞争力,而"文化元... 详细信息

首先,运用贸易竞争指数、显性比较优势指数等指标测算中国文化产品的出口竞争力水平,研究结果发现,中国文化产品的出口竞争力在逐渐提高,但不同类别文化产品的出口竞争力差异较大,中国文化产品"物的类别"具有较高的出口竞争力,而"文化元素"的出口竞争力则较弱.其次,运用 2008-2022 年期间美、英、德等六个区域的引力模型研究中国文化产品出口竞争力的重要影响因素,结果表明高等教育入学率、文化产业的研发投入、知识产权发展水平等对中国文化产品的出口竞争力具有显著正的影响,而中国与这六个区域之间的文化距离则对我国文化产品的出口竞争力具有显著负的影响.

关键词：文化产品出口竞争力引力模型

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福建农林大学学报（自然科学版） 2025年第1期54卷 110-116页

作者：苏进博王锦祥殷光文福建农林大学未来技术学院福建福州350002 福建省农业科学院畜牧兽医研究所福建福州350013

【目的】建立兔源支气管败血波氏杆菌(Bb)的快速检测方法,用于兔波氏杆菌病的诊断。【方法】以Bb的fimX基因为靶基因,设计特异性引物并构建质粒标准品。在此基础上建立检测兔源Bb的SYBR GreenⅠ荧光定量PcR方法,对该方法的特异性、敏感... 详细信息

【目的】建立兔源支气管败血波氏杆菌(Bb)的快速检测方法,用于兔波氏杆菌病的诊断。【方法】以Bb的fimX基因为靶基因,设计特异性引物并构建质粒标准品。在此基础上建立检测兔源Bb的SYBR GreenⅠ荧光定量PcR方法,对该方法的特异性、敏感性和重复性进行评价,并将该方法初步应用于临床样品的检测。【结果】荧光定量PcR方法仅对兔源Bb的检测结果呈阳性,对其他常见兔源病原菌的检测结果均呈阴性;对质粒标准品的最低检测限为13.8拷贝·μL^(-1),敏感性是普通PcR方法的10倍;批内重复性试验的变异系数小于2%,批间重复性试验的变异系数小于3%;对68份临床样品进行检测,阳性检出率为39.71%,比普通PcR方法的高2.95%。【结论】建立的SYBR GreenⅠ荧光定量PcR方法特异性强、敏感性高、重复性好,且对临床样品的阳性检出率比普通PcR方法高,为兔源Bb的快速检测和防控提供了技术支持。

关键词：兔兔波氏杆菌病支气管败血波氏杆菌荧光定量PcR方法检出率

Leaf c:N:P stoichiometric homeostasis of a Robinia pseudoacacia plantation on the Loess Plateau

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Journal of Forestry Research 2023年第4期34卷 929-937页

作者： Zhuoxia su Bingqian su Shenglin Mao Zhouping Shangguan State Key Laboratory of Soil Erosion and Dryland Farming on the Loess Plateau Northwest A&F UniversityYangling 712100ShaanxiPeople’s Republic of China

Homeostasis is the adaptability of a species to a changing ***,the ecological stoichiometric homeostasis of Robinia pseudoacacia *** diff erent climatic regions is poorly understood but could provide insights into its adaptability in the loess hilly *** study sampled 20 year-old *** plantations at 10 sites along a north–south transect on the Loess *** in the ecological stoichiometric characteristics of leaf and soil carbon,nitrogen,and phosphorus were analysed and homeostatic characteristics of leaf ecological stoichiometric parameters in diff erent climates were identifi *** aff ecting leaf stoichiometry were *** results show that *** leaves were rich in nitrogen and defi cient in phosphorous during tree growth and *** and phosphorous levels in the soils of the loess region were lower than the average in soils in the rest of *** ecological stoichiometric parameters of *** leaves in two diff erent climates were considered“strictly homeostasis”.Precipitation,available phosphorus,and soil c:P were the main factors aff ecting the variation of c:N:P stoichiometry of *** *** in the loess hilly region has strong ecologically homeostatic characteristics and suggests that it is well-adapted to the area.

关键词： Loess Plateau Robinia pseudoacacia Ecological stoichiometry Homeostasis

Shock Formation for 2D Isentropic Euler Equations with Self-similar Variables

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chinese Annals of Mathematics,Series B 2024年第3期45卷 349-412页

作者： Wenze su School of Mathematical Sciences Fudan UniversityShanghai 200433China

The author studies the 2D isentropic Euler equations with the ideal gas *** exhibits a set of smooth initial data that give rise to shock formation at a single point near the planar *** solutions to the 2D isentropic Euler equations are associated with non-zero vorticity at the shock and have uniform-in-time-1/3-Holder ***,these point shocks are of self-similar type and share the same profile,which is a solution to the 2D self-similar Burgers *** proof of the solutions,following the 3D construction of Buckmaster,Shkoller and Vicol(in 2023),is based on the stable 2D self-similar Burgers profile and the modulation method.

关键词： 2D isentropic Euler equations Shock formation Self-similar solution

cretaceous Meteorite Impact-Induced Initial subduction:Records of highly Siderophile Element Abundances and Re-Os Isotopes in Ophiolites

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Journal of Earth Science 2022年第6期33卷 1526-1534页

作者： Benxun su Key Laboratory of Mineral Resources Institute of Geology and GeophysicsChinese Academy of SciencesBeijing100029China University of chinese Academy of Sciences Beijing100049China

compiled global ophiolite data reveal that cretaceous ophiolites exhibit broaden variations in 187Re/188Os and ^(187)Os/^(188)Os values,increases in Re concentrations and thus Re/Os ratios in all peridotites and chromitites,and additional increased PPGE/IPGE(Pd-subgroup platinum-group element(PGE)/Ir-subgroup PGE)ratios in chromitites and dunites relative to pre-cretaceous *** compositional changes in cretaceous ophiolites,which mostly formed in subduction initiation settings,cannot be attributed solely to involvement of subducting or previously subducted crustal ***,the author proposes a cretaceous meteorite impact model that led to impact-induced disruption of oceanic lithosphere,asthenosphere upwelling,subduction initiation at edges of laterally spreading ***-pressure and high-temperature conditions during the impacts caused melting of the meteorites and the ambient crustal and mantle rocks,producing hybrid melts containing partially un-melted *** materials contributed to the elevated ^(187)Os/^(188)Os values,Re and Re/Os ratios,whereas the undifferentiated meteorite accounted for the increases in the PPGE/IPGE and decreased ^(187)Os/^(188)Os *** pressure and super-reduced phases were likely generated by this process and were subsequently transported into the newly formed mantle peridotites and chromitites of future *** remaining meteoritic and lithospheric fragments most likely sank deeper and were distributed widely in the convecting mantle to produce the observed global compositional heterogeneities.

关键词： Re-Os isotopes ophiolites PGE meteorites subduction initiation oceanic lithosphere