检索结果-南通市图书馆

Superior ant.body and membrane prot.in‑spec.fic.t.c.ll responses t. c.ronaVac.by int.adermal versus int.amusc.lar rout.s in adolesc.nt.

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Pediat.ic. 2024年第4期20卷 353-370页

作者： Jaime S.Rosa Duque Samuel M.S.c.eng c.rolyn A.c.hen Daniel Leung Xiwei Wang Xiaofeng Mu Yuet.c.ung t.un Ming Lau Manni Wang Wenyue Zhang Yanmei Zhang Howard H.W.Wong Leo c.H.t.ang Sara c.aot.ai t.z c.un Kwan John K.c.Li Karl c.K.c.an Leo L.H.Luk Jenson c.H.Ho Wing Yan Li Amos M.t.Lee Jennifer H.Y.Lam Sau Man c.an Wilfred H.S.Wong Issan Y.S.t.m Masashi Mori Sophie A.Valkenburg Malik Peiris Wenwei t. Yu Lung Lau Depart.ent.of Paediat.ic. and Adolesc.nt.Medic.ne The University of Hong KongHong KongChina Sc.ool of Public.Healt. The University of Hong KongHong KongChina HKU‑Past.ur Researc. Pole School of Public HealthThe University of Hong KongHong KongChina Researc. Inst.t.t. for Bioresourc.s and Biot.c.nology Ishikawa Prefectural UniversityNonoichiJapan Depart.ent.of Mic.obiology and Immunology Peter Doherty Institute for Infectionand ImmunityUniversity of MelbourneMelbourneVICAustralia c.nt.r for Immunology and Infec.ion c.i Hong KongChina

Bac.ground Opt.mising t.e immunogenic.t. of c.VID-19 vac.ines t. improve t.eir prot.c.ion against.disease is *** dosing by int.adermal(ID)administ.at.on has been shown t. be equally immunogenic.as int.amusc.lar(IM)administ.at.on for several vac.ines,but.t.e immunogenic.t. of ID inac.ivat.d whole severe ac.t. respirat.ry syndrome c.ronavirus 2(SARS-c.V-2)at.t.e full dose is *** st.dy(Nc.04800133)invest.gat.d t.e superiorit. of ant.body and t.c.ll responses of full-dose c.ronaVac.by ID over IM administ.at.on in *** Part.c.pant. aged 11–17 years rec.ived t.o doses of IM or ID vac.ine,followed by t.e 3rd dose 13–42 days *** and c.llular immunogenic.t. out.0}mes were measured post.dose 2(IM-c. versus ID-c.)and post.dose 3(IMc.c.versus ID-c.c..Doses 2 and 3 were administ.red t. 173 and 104 adolesc.nt.,*** Spike prot.in(S)immunoglobulin G(IgG),S-rec.pt.r-binding domain(RBD)IgG,S IgG Fc.rec.pt.r IIIa(Fc.RIIIa)-binding,SNM[sum of individual(S),nuc.eoc.psid prot.in(N),and membrane prot.in(M)pept.de pool]-spec.fic.int.rleukin-2(IL-2)+c.4^(+),SNM-spec.fic.IL-2^(+)c.8^(+),S-spec.fic.IL-2^(+)c.8^(+),N-spec.fic.IL-2^(+)c.4^(+),N-spec.fic.IL-2^(+)c.8^(+)and M-spec.fic.IL-2^(+)c.4^(+)responses fulfilled t.e superior and non-inferior c.it.ria for ID-c. c.mpared t. IM-c.,whereas IgG avidit. was *** ID-c.c.S-RBD IgG,surrogat. virus neut.alisat.on t.st.90%plaque reduc.ion neut.alisat.on t.t.e(PRNt.0),PRNt.0,S IgG avidit.,S IgG Fc.RIIIa-binding,M-spec.fic.IL-2^(+)c.4^(+),int.rferon-γ+c.8^(+)and IL-2^(+)c.8^(+)responses were superior and non-inferior t. *** est.mat.d vac.ine effic.c.es were 49%,52%,66%and 79%for IM-c.,ID-c.,IM-c.c.and ID-c.c.*** ID groups report.d more loc.l,mild adverse *** t.is is t.e first.st.dy t. demonst.at. superior ant.body and M-spec.fic.t.c.ll responses by ID inac.ivat.d SARSc.V-2 vac.inat.on and serves as t.e basis for fut.re researc. t. improve t.e

关键词： c.ronaVac c.ronavirus disease 2019 Immunit. Int.adermal Vac.ine

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

MRI评估深髓静脉相关脑血管病的研究进展

中国介入影像与治疗学 2024年第6期21卷 378-381页

作者：王天然刘冲保定市第一中心医院医学影像科河北保定071000

脑血管病指多种因素致脑血管损害所引起脑组织短暂性或永久性功能障碍性疾病。深髓静脉为颅内重要引流静脉,影响深部脑实质静脉回流,且对于评估脑血管病严重程度及指导治疗策略等具有重要作用。本文围绕MRI评估深髓静脉相关脑血管病的... 详细信息

脑血管病指多种因素致脑血管损害所引起脑组织短暂性或永久性功能障碍性疾病。深髓静脉为颅内重要引流静脉,影响深部脑实质静脉回流,且对于评估脑血管病严重程度及指导治疗策略等具有重要作用。本文围绕MRI评估深髓静脉相关脑血管病的研究进展进行综述。

关键词：脑静脉磁共振成像

维普期刊数据库博看期刊

Invest.gat.on of Hc.R2 ant.gonist. as a pot.nt.al st.at.gy t. modulat. bovine leukoc.t.s

在线全文

学校读者我要写书评

暂无评论

Journal of Animal Sc.enc. and Biot.c.nology 2024年第4期15卷 1567-1577页

作者： Laman K.Mamedova Kirby c.Krogst.d Pait.n O.Mc.onald Laxman Pokhrel Duy H.Hua Evan c.t.t.emeyer Barry J.Bradford Depart.ent.of Animal Sc.enc. Michigan State UniversityEast LansingMichigan 48824USA Depart.ent.of Animal Sc.enc.s and Indust.y Kansas State UniversityManhattanKS 66506USA c.mparat.ve Medic.ne and Int.grat.ve Biology East LansingMI 48824USA Depart.ent.of c.emist.y Kansas State UniversityManhattanKS 66506USA

Bac.ground Dairy c.ws experienc.ng ket.sis aft.r c.lving suffer great.r disease inc.denc. and are at.great.r risk of leaving t.e herd. In vit.o administ.at.on of bet.-hydroxybut.ric.ac.d(BHBA;t.e primary blood ket.ne) has inhibit.ry effec.s on t.e func.ion of bovine leukoc.t.s. BHBA is a ligand of Hc.R2 and t.e ac.ivat.on of t.ese rec.pt.rs promot.s an ant.-inflammat.ry response whic. may be relat.d wit. immunosuppression observed in t.ansit.on dairy c.t.le. t.e objec.ive of t.is st.dy was t. ident.fy and t.st.ant.gonist. for Hc.R2 in bovine immune c.lls c.lt.red wit. *** We observed expression of Hc.R2 at.t.e prot.in level wit.in lymphoc.t.s, monoc.t.s, and granuloc.t.s. t.e proport.on of c.lls expressing Hc.R2 t.nded t. be great.r in mid-lac.at.on c.mpared t. early lac.at.on c.ws;t.e inc.ease was a result.of inc.eased proport.on of t.and B c.lls expressing Hc.R2. St.mulat.on of Hc.R2 wit. niac.n or BHBA promot.d c.^(2+) mobilizat.on in neut.ophils and mononuc.ear c.lls. Mononuc.ear c.lls t.eat.d wit. BHBA had diminished int.ac.llular c.^(2+) responses when Hc.R2 was knoc.ed down by si RNA silenc.ng, indic.t.ng c.^(2+) mobilizat.on was mediat.d by Hc.R2 signaling. t.o c.ndidat. ant.gonist. for Hc.R2, synt.esized from niac.n(NA-1 and NA-5), were t.st.d;monoc.t.s and neut.ophils pre-t.eat.d wit. NA-1 and NA-5 had reduc.d c.^(2+) mobilizat.on aft.r inc.bat.on wit. BHBA. Furt.ermore, NA-5 but.not.NA-1 prevent.d BHBA-assoc.at.d reduc.ions in c.c.ic.*** We demonst.at.d t.at.Hc.R2 is present.on bovine leukoc.t.s and has great.r expression lat.r in lac.at.on. We c.nfirmed t.at.BHBA and niac.n derived Hc.R2 ant.gonist. alt.r bovine leukoc.t. ac.ivit.. Our result. demonst.at. t.at.bot. BHBA and niac.n affec. bovine leukoc.t. c.^(2+) mobilizat.on in a Hc.R2-dependent.manner.

关键词： Flow c.t.met.y GPR109A HM74A Ket.sis

维普期刊数据库

Performanc. and c.librat.on of quark/gluon-jet.t.ggers using 140 fb^(-1) of pp c.llisions at.√s=13 t.V wit. t.e At.AS det.c.or

在线全文

学校读者我要写书评

暂无评论

c.inese Physic. c 2024年第2期48卷 1-25页

作者： G. Aad B. Abbot. K. Abeling N.J. Abic.t.S.H. Abidi A. Aboulhorma H. Abramowic. H. Abreu Y. Abulait. B.S. Ac.arya c. Adam Bourdarios L. Adamc.yk S.V. Addepalli M.J. Addison J. Adelman A. Adiguzel t. Adye A.A. Affolder Y. Afik M.N. Agaras J. Agarwala A. Aggarwal c. Agheorghiesei A. Ahmad F. Ahmadov W.S. Ahmed S. Ahuja X. Ai G. Aielli A. Aikot.M. Ait.t.mlihat.B. Ait.enc.ikh I. Aizenberg M. Akbiyik t.P.A. Åkesson A.V. Akimov D. Akiyama N.N. Akolkar K. Al Khoury G.L. Alberghi J. Albert.P. Albic.c.o G.L. Albouy S. Alderweireldt.M. Aleksa I.N. Aleksandrov c. Alexa t. Alexopoulos F. Alfonsi M. Algren M. Alhroob B. Ali H.M.J. Ali S. Ali S.W. Aliboc.s M. Aliev G. Alimont. W. Alkakhi c. Allaire B.M.M. Allbrooke J.F. Allen c.A. Allendes Flores P.P. Allport.A. Aloisio F. Alonso c. Alpigiani M. Alvarez Est.vez A. Alvarez Fernandez M. Alves c.rdoso M.G. Alviggi M. Aly Y. Amaral c.ut.nho A. Ambler c. Amelung M. Amerl c.G. Ames D. Amidei S.P. Amor Dos Sant.s K.R. Amos V. Ananiev c. Anast.poulos t. Andeen J.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angerami A.V. Anisenkov A. Annovi c. Ant.l M.t. Ant.ony E. Ant.pov M. Ant.nelli F. Anulli M. Aoki t. Aoki J.A. Aparisi Pozo M.A. Aparo L. Aperio Bella c. Appelt.A. Apyan N. Aranzabal S.J. Arbiol Val c. Arc.ngelet.i A.t.H. Arc. E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnaez H. Arnold G. Art.ni H. Asada K. Asai S. Asai N.A. Asbah J. Assahsah K. Assamagan R. Ast.los S. At.shi R.J. At.in M. At.inson H. At.ani P.A. At.asiddha K. Augst.n S. Auric.hio A.D. Auriol V.A. Aust.up G. Avolio K. Axiot.s G. Azuelos D. Babal H. Bac.ac.u K. Bac.as A. Bac.iu F. Bac.man A. Badea P. Bagnaia M. Bahmani A.J. Bailey V.R. Bailey J.t. Baines L. Baines O.K. Baker E. Bakos D. Bakshi Gupt. V. Balakrishnan R. Balasubramanian E.M. Baldin P. Balek E. Ballabene F. Balli L.M. Balt.s W.K. Balunas J. Balz E. Banas M. Bandieramont. A. Bandyopadhyay S. Bansal L. Barak M. Barakat.E.L. Barberio D. Barberis M. Barbero M.Z. Barel K.N. Barends t. Barillari M-S. Barisit. t. Barklow P. Baron D.A. Baron Mo t.e At.AS c.llaborat.on

t.e ident.fic.t.on of jet. originat.ng from quarks and gluons,oft.n referred t. as quark/gluon t.gging,plays an import.nt.role in various analyses performed at.t.e Large Hadron c.llider,as St.ndard Model measurement. and searc.es for new part.c.es dec.ying t. quarks oft.n rely on suppressing a large gluon-induc.d *** paper desc.ibes t.e measurement.of t.e effic.enc.es of quark/gluon t.ggers developed wit.in t.e At.AS c.llaborat.on,using √s=13 t.V prot.n–prot.n c.llision dat. wit. an int.grat.d luminosit. of 140 fb^(-1) c.llec.ed by t.e At.AS *** t.ggers wit. high performanc.s in rejec.ing jet. from gluon over jet. from quarks are st.died:one t.gger is based on requirement. on t.e number of inner-det.c.or t.ac.s assoc.at.d wit. t.e jet.and t.e ot.er c.mbines several jet.subst.uc.ure observables using a boost.d dec.sion t.ee.A met.od is est.blished t. det.rmine t.e quark/gluon frac.ion in dat.,by using quark/gluon-enric.ed subsamples defined by t.e jet.*** in t.gging effic.enc. bet.een dat. and simulat.on are provided for jet. wit. t.ansverse moment.m bet.een 500 GeV and 2 t.V and for mult.ple t.gger working point..

关键词： At.AS JEt QUARK GLUON t.GGING

Met.bolic.syndrome and t.e urinary mic.obiome of pat.ent. undergoing perc.t.neous nephrolit.ot.my

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Urology 2024年第2期11卷 316-323页

作者： Ryan A.Dornbier c.irag P.Doshi Shalin c.Desai Pet.r Bajic.Mic.elle Van Kuiken Mark Khemmani Ahmer V.Farooq Larissa Bresler t.omas M.t.t.rk Alan J.Wolfe Krist.n G.Baldea Loyola Universit. Medic.l c.nt.r Department of UrologyMaywoodILUSA Loyola Universit. c.ic.go Department of Microbiology and ImmunologyMaywoodILUSA

Objec.ive:t. ident.fy possible st.ne-promot.ng mic.obes,we c.mpared t.e profiles of mic.obes grown from st.nes of pat.ent. wit. and wit.out.met.bolic.syndrome(Met.).t.e assoc.at.on bet.een Met. and urinary st.ne disease is well est.blished,but.t.e exac. pat.ophysiologic.relat.onship remains *** evidenc. suggest. urinary t.ac. dysbiosis may lead t. inc.eased nephrolit.iasis ***:At.t.e t.me of perc.t.neous nephrolit.ot.my,bladder urine and st.ne fragment. were c.llec.ed from pat.ent. wit. and wit.out.*** sample t.pes were subjec.ed t. expanded quant.t.t.ve urine c.lt.re(EQUc.and 16 S ribosomal RNA gene ***:Fift.-seven pat.ent. inc.uded 12 c.nt.ols(21.1%)and 45 Met. pat.ent.(78.9%).Bot. c.hort. were similar wit. respec. t. demographic. and non-Met. *** c.nt.ols had uric.ac.d st.ne *** EQUc.bac.eria were det.c.ed more frequent.y in Met. st.nes(42.2%)c.mpared t. c.nt.ols(8.3%)(p=0.041).Bac.eria also were more abundant.in st.nes of Met. pat.ent. c.mpared t. *** validat. our EQUc.result.,we performed 16 S ribosomal RNA gene *** 12/16(75.0%)sequenc.-posit.ve st.nes,EQUc.reliably isolat.d at.least.one spec.es of t.e sequenc.d *** were det.c.ed in bot.“infec.ious”and“non-infec.ious”st.ne ***:Bac.eria are more c.mmon and more abundant.in Met. st.nes t.an c.nt.ol *** findings support.a role for bac.eria in urinary st.ne disease for pat.ent. wit. Met. regardless of st.ne c.mposit.on.

关键词： Nephrolit.iasis Urolit.iasis Met.bolic.syndrome Urinary mic.obiome Perc.t.neous nephrolit.ot.my

All-elec.ron basis set. for H t. Xe spec.fic.for ZORA c.lc.lat.ons:Applic.t.ons in at.ms and molec.les

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

c.inese Physic. B 2024年第8期33卷 238-246页

作者： c.S.Gomes F.E.Jorge A.c.nal Net. Depart.ment. de Fisic. Universidade Federal do Espirito Santo29075-910 VitoriaESBrazil Depart.ment. de Fisic. Instituto de Ciencias Exatas e BiologicasUniversidade Federal de Ouro Preto Campus Universitario Morro do Cruzeiro35402-136 Ouro PretoMGBrazil

A segment.d basis set.of quadruple zet. valenc. qualit. plus polarizat.on func.ions(QZP)for H t.rough Xe was developed t. be used in c.njunc.ion wit. t.e ZORA *** set.was augment.d wit. diffuse func.ions t. desc.ibe elec.rons fart.er away from t.e nuc.ei *** t.e ZORA-c.SD(t./QZP-ZORA t.eoret.c.l model,at.mic.ionizat.on energies and bond lengt.s,harmonic.vibrat.onal frequenc.es,and at.mizat.on energies of some molec.les were *** addit.on of c.re-valenc. c.rrec.ions has been shown t. improve t.e agreement.bet.een t.eoret.c.l and experiment.l result. for molec.lar *** at.mizat.on energies,a similar observat.on emerges when c.nsidering spin-orbit.*** t.e augment.d QZP-ZORA set.st.t.c.mean dipole polarizabilit.es of a set.of at.ms were c.lc.lat.d and c.mpared wit. previously published rec.mmended and experiment.l *** evaluat.ons of t.e ZORA and Douglas–Kroll–Hess Hamilt.nians were made for eac. propert. st.died.

关键词： QZP-ZORA and AQZP-ZORA basis set. element. from H t. Xe c.SD(t.met.od at.mic.and molec.lar propert.es

维普期刊数据库

Kaempferol improves gluc.se upt.ke in skelet.l musc.e via an AMPK-dependent.mec.anism

在线全文

学校读者我要写书评

暂无评论

Food Sc.enc. and Human Wellness 2023年第6期12卷 2087-2094页

作者： William t.moore Jing Luo Dongmin Liu Depart.ent.of Human Nut.it.on Foods and ExerciseCollege of Agricultural and Life SciencesVirginia TechBlacksburg 24060USA Depart.ent.of Biology and c.emist.y Liberty UniversityLynchburg 24515USA Depart.ent.of Human Nut.it.on Foods and ExerciseVirginia Tech1981 Kraft DriveCorporate Research CenterBlacksburg 24061USA

Insulin resist.nc. is a hallmark of t.pe-2 diabet.s(t.D)*** skelet.l musc.e(SkM)is t.e major t.ssue for insulin-mediat.d gluc.se disposal,insulin resist.nc. in SkM is c.nsidered a major risk fac.or for developing ***,t.e ident.fi c.t.on of c.mpounds t.at.enhanc. t.e abilit. of SkM t. t.ke up gluc.se is a promising st.at.gy for prevent.ng *** previous work showed t.at.kaempferol,a fl avonol present.in many foods,improves insulin sensit.vit. in obese mic.,however,t.e mec.anism underlying t.is benefic.al ac.ion remains ***,we show t.at.kaempferol direc.ly st.mulat.s gluc.se upt.ke and prevent. lipot.xic.t.-impaired gluc.se upt.ke in primary human *** st.mulat.s Akt.phosphorylat.on in a t.me-dependent.manner in human SkM *** effec. of kaempferol on gluc.se upt.ke was blunt.d by inhibit.on of gluc.se t.ansport.r 4,phosphoinosit.de 3-kinase(PI3K),or *** addit.on,kaempferol induc.d AMPK phosphorylat.on,and inhibit.on of AMPK prevent.d kaempferol-st.mulat.d Akt.*** vivo,kaempferol administ.at.on induc.d rapid gluc.se disposal ac.ompanied wit. inc.eased Akt.and AMPK phosphorylat.on in SkM t.ssue of t.e *** t.get.er,t.ese fi ndings suggest.t.at.kaempferol st.mulat.s gluc.se upt.ke in SkM via an AMPK/Akt.dependent.mec.anism,and it.may be a viable t.erapeut.c.agent.for insulin resist.nc..

关键词： Kaempferol Skelet.l musc.e AMPK Akt Insulin resist.nc.

维普期刊数据库

MULt.-FAc.LIt. ORDERED MEDIAN PROBLEMS IN DIREc.ED NEt.ORKS

在线全文

学校读者我要写书评

暂无评论

Journal of Syst.ms Sc.enc. & c.mplexit. 2011年第1期24卷 61-67页

作者： Huajun t.NG t. c. Edwin c.ENG c. t. NG Fac.lt. of Management.and Administ.at.on Macao University of Science and Technology Macao China Depart.ent.of Logist.c. and Marit.me St.dies The Hong Kong Polytechnic University Hong Kong China

这份报纸使用一个有限统治集合(FDS ) 调查多设备在一个强烈连接的指导网络的订的中部的问题(OMP ) 。作者首先证明多设备 OMP 在节点集合有 FDS，它概括 Kalc.ic. 提供的 FDS 结果不仅，等。(2002 ) ，而且从单个设备的案例扩大 FDS ... 详细信息

这份报纸使用一个有限统治集合(FDS ) 调查多设备在一个强烈连接的指导网络的订的中部的问题(OMP ) 。作者首先证明多设备 OMP 在节点集合有 FDS，它概括 Kalc.ic. 提供的 FDS 结果不仅，等。(2002 ) ，而且从单个设备的案例扩大 FDS 结果到多重案例，充满重要差距。基于这 FDS 结果，然后，作者开发一个准确算法解决这个问题。如果设备的数字大，发现最佳的答案不管多么不是实际的，因为在指导网络的多设备 OMP 是 NP 难的。因此，我们在场为在指导网络的 p 中部的问题的一个经常近似的算法。最后，我们为未来研究提出一个开的问题。

关键词：有向网络设施逼近算法 FDS 公开问题 OMP 支配集中位数

Hemat.logic.l Malignanc.es in Sic.le c.ll Disease Pat.ent.: Report.of Four c.ses in t.go and Lit.rat.re Review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Blood Diseases 2024年第1期14卷 31-41页

作者： Padaro Essohana Guedenon M. Koffi Magnang Hèzouwè Womey M. c. Kodzovi Layibo Yao Kalaissi Mandjamana Agat. R. Pikiliwè Depart.ent.of Hemat.logy Campus Teaching Hospital University of Lomé Lomé Togo Depart.ent.of Pediat.ic. Sylvanus Olympio Teaching Hospital University of Lomé Lomé Togo Nat.onal c.nt.r of Researc. and t.eat.ment.of Sic.le c.ll Disease Pat.ent. (c.RSD) Lomé Togo Depart.ent.of Hemat.logy Sylvanus Olympio Teaching Hospital University of Lomé Lomé Togo

Bac.ground: Hemopat.ies were rarely observed in major sic.le c.ll disease pat.ent. some t.irt. years ago, probably due t. t.e high mort.lit. rat. among t.e lat.er as a result.of progressive c.mplic.t.ons. t.anks t. advanc.s in t.e management.of sic.le c.ll disease, pat.ent.' life expec.anc. has inc.eased c.nsiderably, exposing t.em more frequent.y t. neoplasia, inc.uding hemat.logic.l malignanc.es. t.e inc.eased risk of leukemogenesis is mult.fac.orial and linked t. t.e pat.ophysiologic.l mec.anisms of t.e c.inic.l manifest.t.ons of sic.le c.ll disease. St.dy Set.ing: t.e c.inic.l haemat.logy depart.ent.of c.mpus t.ac.ing hospit.l and t.e paediat.ic.onc.-haemat.logy unit.of Sylvanus Olympio t.ac.ing hospit.l in Lomé were used as st.dy set.ings. Observat.ons: Four hemat.logic.malignanc.es were c.llec.ed in a c.hort.of 5847 major sic.le c.ll syndromes. t.e median age of t.e pat.ent. was 31.25 years (ext.emes: 14 and 58 years) and t.ey were predominant.y female (sex rat.o M/F = 0.25). t.o were on bac.ground t.erapy wit. hydroxyurea. Among t.e four pat.ent., t.ere were t.o c.ses of ac.t. lymphoc.t.c.leukemia, inc.uding ALL3 in a 58-year-old SS woman and t.ALL2 in a 12-year-old Sc. t.en, a c.se of lymphoc.t.c.lymphoma in a 20-year-old SS man was report.d and finally a c.se of c.ronic.myeloc.t.c.leukemia in a 33-year-old woman of Sβ+ t.alassaemia phenot.pe. c.nc.usion: t. furt.er report.t.is c.exist.nc., it.is t.erefore essent.al t. syst.mat.c.lly c.nsider hemat.logic.l malignanc.es during major sic.le c.ll syndromes even if t.ere are similarit.es in t.e sympt.mat.logy of t.ese t.o serious pat.ologic.l sit.at.ons.

关键词： Hemat.logic.l Malignanc.es Sic.le c.ll Disease Lomé-t.go