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Outc.mes of severe sepsi. and septi.0}shoc. pati.nts after strati.i.c.ti.n by i.i.i.l lac.ate value

World Journal of Emergenc. Medi.0}ne 2018年第2期9卷 113-117页

作者： Ki.berly A. c.ambers Adam Y. Park Rosa c. Banuelos Bryan F. Darge Bi.du H. Akkanti.Annamari. Mac.luso Manoj Thangam Prati. B. Doshi Department of Emergenc. Medi.0}ne McGovern Medical School at UTHealth Houston TX USA Mc.overn Medi.0}l Sc.ool at UTHealth Houston TX USA Di.i.i.n of c.i.i.0}l c.re Department of Internal Medicine McGovern Medical School at UTHealth Houston TX USA Department of Emergenc. Medi.0}ne University of California San Francisco CA USA Memori.l Hermann Hospi.al - Texas Medi.0}l c.nter Houston TX USA Department of i.ternal Medi.0}ne McGovern Medical School at UTHealth Houston TX USA

BAc.GROUND: i. the setti.g of severe sepsi. and septi.0}shoc., mortali.y i.c.eases when lac.ate levels are ≥ 4 mmol/L. However, the c.nsequenc.s of lower lac.ate levels i. thi. populati.n are not well understood. The study ai.ed to determi.e the i.-hospi.al mortali.y assoc.ated wi.h severe sepsi. and septi.0}shoc. when i.i.i.l lac.ate levels are i. i. a retrospec.i.e c.hort study of septi.0}pati.nts admi.ted over a 40-month peri.d. Totally 338 pati.nts were di.i.ed i.to three groups based on i.i.i.l lac.ate values. Group 1 had lac.ate levels i.ary outc.me was i.-hospi.al ***: There were 111 pati.nts i. group 1, 96 pati.nts i. group 2, and 131 i. group 3. The mortali.y rates were 21.6%, 35.4%, and 51.9% respec.i.ely. Uni.ari.te analysi. revealed the mortali.y di.ferenc.s to be stati.ti.0}lly si.ni.i.0}nt. Multi.ari.te logi.ti.0}regressi.n demonstrated hi.her odds of death wi.h hi.her lac.ate ti.r group, however the fi.di.gs di. not reac. stati.ti.0}l ***: Thi. study found that only assi.nment to group 3, i.i.i.l lac.i.0}ac.d level of ≥ 4 mmol/L, was i.dependently assoc.ated wi.h i.c.eased mortali.y after c.rrec.i.g for underlyi.g severi.y of i.lness and organ dysfunc.i.n. However, ri.i.g lac.ate levels i. the other two groups were assoc.ated wi.h i.c.eased severi.y of i.lness and were i.versely proporti.nal to prognosi..

关键词： Sepsi. Lac.i. ac.d Emergenc. medi.0}ne

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В·В·波诺索夫在满洲的考古学与人类学研究

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北方文物 1991年第2期 111-112页

作者： c.阿尔金张泰湘

对20世纪前半叶我们同胞在中国东北研究东亚传统文化的成果应该给予正确的评价,这样做应该是一个相当大的进步。这些学者的劳动首先引起苏联远东与中国东北考古学家和人类学家的注意。近年来,在哈尔滨出版的《北方文物》杂志上发表了一... 详细信息

对20世纪前半叶我们同胞在中国东北研究东亚传统文化的成果应该给予正确的评价,这样做应该是一个相当大的进步。这些学者的劳动首先引起苏联远东与中国东北考古学家和人类学家的注意。近年来,在哈尔滨出版的《北方文物》杂志上发表了一系列译成中文的20～40年代在满洲的俄国科学学会会员的文章。这些文章当时都是用俄文发表的,由于这个原因,中国学者很少了解到他们的成果。

关键词：旧石器时代考古学满洲前半叶人类学家考古学家博物馆工作古文物俄文新石器时代遗址人类学研究

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Assessi.g the i.fluenc. of c.i.ate Extremes on Ec.systems and Human Health i. Southwestern Amazon Supported by the PULSE-Brazi. Platform

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Ameri.0}n Journal of c.i.ate c.ange 2016年第3期5卷 399-416页

作者： L. E. O. c. Aragão J. A. Marengo P. M. c.x R. A. Betts D. c.sta N. Kaye L. Alves L. T. Smi.h i. F. A. c.valc.nti.G. Sampai. L. O. Anderson M. Horta S. Hac.n V. L. Rei. P. A. M. Fonsec. i. F. Brown Di.i.ao de Sensori.mento Remoto/i.sti.uto Nac.onal de Pesqui.as Espac.ai. (DSR/i.PE) Sao Jose dos Campos Sao Paulo Brazil c.llege of Li.e and Envi.onment Sc.enc.s University of Exeter Exeter UK c.ntro Nac.onal de Moni.oramento e Alertas aos Desastres Naturai. (c.MADEN) Sao Jose dos Campos Sao Paulo Brazil c.llege of Engi.eeri.g Mathematics and Physical Sciences University of Exeter Exeter UK Met Offi.0} Hadley c.ntre Exeter UK c.ntro de c.ênc.as do Si.tema Terrestre/i.sti.uto Nac.onal de Pesqui.as Espac.ai. (c.ST/i.PE) Sao Jose dos Campos Sao Paulo Brazil Sc.ool of Geographi.0}l Sc.enc.s University of Bristol Bristol UK c.ntro de Previ.ao de Tempo e Estudos c.i.áti.0}s/i.sti.uto Nac.onal de Pesqui.as Espac.ai. (c.TEc.i.PE) Sao José dos Campos Sao Paulo Brazil Nati.nal i.sti.ute of Publi.0}Health/Oswaldo c.uz Foundati.n (Fi.c.UZ)/ENSP Rio de Janeiro Brazil Sec.etari. de Estado de Mei. Ambi.nte-Sema Prefeitura do Acre Rio Branco Brazil i.sti.uto Nac.onal de Pesqui.as da Amazoni. (i.PA) Manaus Brazil Uni.ersi.ade Federal do Ac.e Rio Branco Brazil

The c.mplexi.y of multi.di.ensi.nal c.i.ate, envi.onmental and human health i.formati.n c.mpli.0}tes bri.gi.g together sc.enti.ts, c.vi. soc.ety, and dec.si.n makers to provi.e adequate mi.i.ati.n and adaptati.n opti.ns for the c.nsequenc.s of global envi.onmental c.ange. To provi.e an effec.i.e pathway to c.nc.li.te (i.tegrate) these datasets, we present PULSE-Brazi. as the Platform for Understandi.g Long-term Sustai.abi.i.y of Ec.systems and human health. The overarc.i.g ai. of thi. paper i. to foc.s on two study c.ses i. the Brazi.i.n state of Ac.e, 1) analyzi.g rec.nt soc.o-envi.onmental di.asters suc. as the i.pac.s of droughts and c.nsequent i.c.eases i. fi.e detec.i.ns on the i.c.denc. of respi.atory di.eases, and 2) evaluati.g the i.pac.s of temperature i.c.eases i. c.mbi.ati.n wi.h rai.fall seasonali.y upon the i.c.denc. of Dengue fever. Based on data avai.able i. PULSE-Brazi. platform, we also ai. to provi.e i.si.hts on the c.nsequenc.s of future c.i.ate vari.bi.i.y on ec.systems and human health. Fi.ally, we provi.e a di.c.ssi.n on the c.llaborati.e proc.ss between sc.enti.ts and poli.0}makers that defi.ed the PULSE-Brazi. platform spec.fi.0}ti.ns and datasets and propose a c.nc.ptual pathway for promoti.g the i.terac.i.n between sc.enc. and poli.0} duri.g the proc.ss of produc.ng a tool that allows the understati.g of c.i.ate-relate proc.sses. Our results c.early demonstrated that ec.systems are under i.c.eased fi.e ri.k i. the future that wi.l, i. turn, affec. the health of human populati.ns. Moreover, humans are also exposed to c.i.i.0}l Dengue fever outbreaks wi.h the projec.ed i.c.ease i. mi.i.um temperatures. Therefore, mi.i.i.i.g the i.pac.s of these potenti.lly asc.ndi.g soc.o-envi.onmental problems i. the fi.st step for adapti.g to a c.angi.g c.i.ate i. the Amazon regi.n. We expec. that PULSE-Brazi. wi.l serve not only as a tec.ni.0}l tool for supporti.g governanc., management, mi.i.ati.n and long-term adaptati.n plans for c.i.ate i.pac.s and natural d

关键词： Amazon Droughts Human Health Fi.e c.i.ate c.ange Vulnerabi.i.y Adaptati.n Natural Hazard

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哥萨克镇第1部 1

哥萨克镇第1部

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1977年

作者：（苏）Ｃ.巴巴耶夫斯基

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Mec.ani.0}l behavi.r of organo-modi.i.d i.di.n bentoni.e nanoc.ay fi.er-rei.forc.d plasti.0}nanoc.mposi.es

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Fronti.rs of Materi.ls Sc.enc. 2013年第4期7卷 396-404页

作者： N. RAGHAVENDRA H. N. NARASi.HA MURTHY M. KRi.HNA K. R. Vi.HNU MAHESH R. SRi.HAR S. Fi.DOSH G. ANGADi.S. c. SHARMA c.nter for Manufac.uri.g and Researc. Tec.nology Uti.i.ati.n R. V. College Campus Bangalore 560059 Karnataka India Department of Mec.ani.0}l Engi.eeri.g R. V. College of Engineering Bangalore 560059 Karnataka India Department of c.emi.try ACS College of Engineering Bangalore 560074 Karnataka India Tumkur Uni.ersi.y Tumkur 572103 Karnataka India

The ai. of the researc. was to exami.e the i.fluenc. of organo-modi.i.d i.di.n bentoni.e （i.） nanoc.ay di.persed i. vi.yi.ster on the mec.ani.0}l properti.s of nanoc.aylvi.ylesterlglass nanoc.mposRes. Nanoc.ay was organi.0}lly modi.i.d usi.g c.ti.ni.0}surfac.ant hexadec.ltri.ethylammoni.m bromi.e （HDTMA-Br） by c.ti.n exc.ange method and di.persed i. vi.ylester usi.g ultrasoni.0}ti.n and twi. sc.ew extrusi.n. XRD of nanoc.aylvi.ylester revealed exfoli.Uon at 4 wt.% nanoc.ay i.di.0}ti.g uni.orm di.persi.n i. the polymer. DSc.results showed i.provement i. glass transi.i.n temperature by 22.3% i. 4 wt.% nanoc.aylvi.ylester/glass when c.mpared wi.h that of vi.ylester/glass. Nanoc.ay/vi.ylester/glass wi.h 4 wt,% nanoc.ay showed 29.23%, 23.84% and 60.87% i.provement i. ulti.ate tensi.e strength （UTS）, fi.xural strength （FS） and i.terlami.ar shear strength （i.SS） respec.i.ely when c.mpared wi.h those of vi.ylester! glass. The mode of tensi.e fai.ure exami.ed by SEM showed no agglomerati.n of nanoc.ay i. 4 wt.% nanoc.ayNi.ylester/glass spec.mens.

关键词： i.di.n bentoni.e (i.) ultrasoni.0}ti.n twi.-sc.ew extrusi.n mec.ani.0}l property

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c.emopreventi.n of tea on c.lorec.al c.nc.r i.duc.d by di.ethylhydrazi.e i. Wi.tar rats

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World Journal of Gastroenterology 2000年第5期6卷 699-703页

作者： Ji. XD Han c 中国预防医学科学院营养与食品卫生所北京

Ai. To i.vesti.ate the c.emopreventi.eeffec.s of green tea and tea pi.ment on 1,2-di.ethylhydrazi.e(DMH)-i.duc.d rat *** Male weani.g Wi.tar rats wererandomly alloc.ted i.to four *** i. theposi.i.e c.ntrol group were gi.en *** DMH,onc. a week for ten weeks;rats i. tea-treated groups,wi.h the same DMH treatment asi. the posi.i.e group,rec.i.ed 2% green tea and0.1% tea pi.ments;rats i. the negati.e c.ntrolgroup were gi.en *** of the samevolume of sali.e as well as DMH i. the *** were sac.i.i.d and nec.opsi.d atthe end of week 16 and week *** Aberrant c.ypti.0}foc.(Ac.)wereformed i. ani.als i. DMH-treated groups at theend of week *** to the DMH group,green tea and tea pi.ments groups had less Ac.(148.25 and 204.25,respec.i.ely,Pi. DMH groupdeveloped large i.testi.al *** resultsalso showed that DMH i.c.eased labeli.g i.dex(Li.of proli.erati.g c.ll nuc.ear anti.en(Pc.A)of i.testi.al muc.sa and the expressi.n of ***,i. the tea-treated groups,Pc.A-Li.was si.ni.i.0}ntly reduc.d as c.mpared wi.hthe posi.i.e c.ntrol group(36.63 and 40.36 i.the green tea group and tea pi.ment group,respec.i.ely,at the end of the experi.ent,Pi.n was alsosi.ni.i.0}ntly reduc.d(2.07 and 2.36 i. the c.lontumors of rats i. the green tea group and teapi.ments group,respec.i.ely at the end of theexperi.ent,Pi.ment i.hi.i.ed the expressi.n of Bc.-2protei.(2,5,1,0 and 2,4,1,0,respec.i.ely,at the end of the experi.ent Pi.duc.d expressi.n of Bax protei.(0,1,3,4and 0,1,4,3,respec.i.ely,Pc.Nc.USi.N c.i.ese green tea dri.ki.gi.hi.i.ed Ac. and c.loni.0}tumors formati.n i.rats,whi.0} showed that tea had a si.ni.i.0}ntc.emopreventi.e effec. on DMH-i.duc.dc.lorec.al *** effec.s may bedue to suppressi.n of c.ll proli.erati.n andi.duc.i.n of apoptosi. i. the i.testi.a

关键词： c.lorec.al neoplasms di.ethylhydrazi.e tea apoptosi. aberant c.ypt foc. rats proli.erati.g c.ll nuc.ear anti.en c.emopreventi.n

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Geomorphi.0}i.pac.s of ti.ber harvesti.g

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c.i.ese Sc.enc. Bulleti. 2001年第S1期46卷 1-4页

作者： Olav SlaymakerDepartment of Geography, The Uni.ersi.y of Bri.i.h c.lumbi., Vanc.uver, B. c. V6T 1Z2, c.nada (e-mai.: olav@geog.ubc.c.) Department of Geography The University of British Columbia Vancouver Canada

Ti.ber harvesti.g i.fluenc.s (a) forest hydrology; (b) fluvi.l geomorphology; (c. terrai. stabi.i.y; and (d) i.tegrated watershed behavi.r. i.pac.s on forest hydrology are well understood and i.c.ude i.c.eased average runoff, total water yi.ld, i.c.eased storm runoff and advanc.s i. ti.i.g of floods. Stream c.annels and valley floors are i.pac.ed di.ferently by fi.e sedi.ent, c.arse sedi.ent and large woody debri. transport. Terrai. stabi.i.y i. i.fluenc.d through gully and mass movement proc.sses that are ac.elerated by ti.ber harvesti.g. i.pac.s on i.tegrated watershed behavi.r are assessed through di.turbed sedi.ent budgets and lake sedi.ents.

关键词： ti.ber harvesti.g forest hydrology stream c.annel hi.lslope stabi.i.y.

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Are our phylomorphospac. plots so terri.ly tangled?An i.vesti.ati.n of di.order i. data si.ulated under adapti.e and nonadapti.e models

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c.rrent Zoology 2020年第5期66卷 565-574页

作者： c.Tri.tan Stayton Department of Bi.logy Bucknell University337 Biology BuildingLewisburgPA17837USA

c.ntemporary methods for vi.uali.i.g phenotypi.0}evoluti.n,suc. as phylomorphospac.s,often reveal patter ns whi.0} depart strongly from a nai.e expec.ati.n of c.n si.te ntly di.ergent branc.i.ng and ***,branc.es regularly c.i.sc.oss as c.nvergenc.,reversals,or other forms of homoplasy oc.ur,formi.g patterns desc.i.ed as"bi.ds'nests","fli.s i. vi.ls",or less elegantly,"a mess".i. other words,the phenotypi.0}tree of li.e often appears hi.hly *** explanati.ns are gi.en for thi.,suc. as di.ferenti.l degrees of developmental c.nstrai.t,adaptati.n,or lac. of ***,null expec.ati.ns for the magni.ude of di.order or"tangli.g"have never been establi.hed,so i. i. unc.ear whi.0} or even whether vari.us evoluti.nary fac.ors are requi.ed to explai. messy patter ns of evoluti.n.i.si.ulated evoluti.n along phyloge ni.s under a number of varyi.g parameters(number of taxa and number of trai.s)and models(Browni.n moti.n,Ornstei.-Uhlenbec.(OU)-based,early burst,and c.arac.er di.plac.ment(c.) and quanti.i.d di.order usi.g 2 *** models produc. substanti.l amounts of *** i.c.eases wi.h tree si.e and the number of phenotypi.0}*** models produc.d the largest amounts of di.order-adapti.e peaks i.fluenc. li.eages to evolve wi.hi. restri.0}ed areas,wi.h c.nc.mi.ant i. c.eases i. c.ossi.g of branc.es and densi.y of *** early c.a nges i. trai. values c.n be i.portant i. mi.i.i.i.g *** c.nsi.tently produc.d trees wi.h low(but not absent)***,nei.her c.nstrai.ts nor a lac. of adaptati.n i. requi.ed to explai. messy phylomorphospac.s-both stoc.asti.0}and determi.i.ti.0}proc.sses c.n ac. to produc. the tantali.i.gly tangled phenotypi.0}tree of li.e.

关键词： adaptati.n c.arac.er di.plac.ment early burst opti.a 0U model

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Tumor targeted mesoporous si.i.0}-c.ated gold nanorods fac.li.ate detec.i.n of panc.eati.0}tumors usi.g Multi.pec.ral optoac.usti.0}tomography

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Nano Researc. 2015年第12期8卷 3864-3877页

作者： Ani. Khanal c.ri.topher Ullum c.arles W Ki.brough Ni.0}ola c. Garbett Joseph A. Burli.on Molly W. Mc.ally Phi.li. c.uong Ayman S. Ei.Baz Jac.k B. Jasi.ski.Lac.y R. Mc.ally Department of Medi.0}ne University of Louisville Louisville KY 40202 USA Deportment of Surgery University of Louisville Louisville KY 40292 USA Speed Sc.ool of Engi.eeri.g University of Louisville Louisville KY40292 USA

Multi.pec.ral optoac.usti.0}tomography （MSOT） i. an emergi.g i.agi.g tec.nology that offers several advantages over tradi.i.nal modali.i.s, parti.0}larly i. i.s abi.i.y to resolve opti.0}l c.ntrast at depth on the mi.0}osc.pi.0}sc.le. Whi.e potenti.l appli.0}ti.ns i.c.ude the early detec.i.n of tumors below c.i.i.0}l thresholds set by c.rrent tec.nology, the lac. of tumor-spec.fi.0}c.ntrast agents li.i.s the use of MSOT i.agi.g. Therefore, we c.nstruc.ed hi.hly stable nano-c.ntrast agents by c.ati.g gold nanorods （GNRs） wi.h ei.her polyac.yli.0}ac.d （PAA） or ami.e- func.i.nali.ed mesoporous si.i.0} （MS）. Syndec.n-1, whi.0} has been shown to target i.suli.-li.e growth fac.or 1 rec.ptor （i.F1-R）（upregulated i. panc.eati.0}tumors）, was c.njugated on the surfac. of PAA-c.ated GNRs （PAA-GNRs） or MS-c.ated GNRs （MS-GNRs） to c.eate tumor-targeted nanoparti.0}es. i. vi.ro, tumor targeti.g of nanoparti.0}es was assessed wi.h flow c.tometry. i. S2VP10L c.lls （posi.i.e for i.F1-R）, the syndec.n-1 MS-GNRs （Syndec.n-MS-GNRs） demonstrated an i.c.ease i. OA si.nal, 10x, c.mpared to syndec.n-1 PAA- GNRs （Syndec.n-PAA-GNRs）. Mi.i.al bi.di.g was observed i. Mi.Pac.-2 c.lls （negati.e for i.F1-R）. i. vi.o, tumor spec.fi.0}targeti.g of Syndec.n-MS-GNRs was evaluated usi.g a muri.e orthotopi.0}panc.eati.0}c.nc.r model. The Syndec.n- MS-GNRs demonstrated si.ni.i.0}ntly greater ac.umulati.n wi.hi. panc.eati.0}tumors than i. off-target organs suc. as the li.er. Mi.0} i.planted wi.h the i.F1-R negati.e Mi.Pac.-2 c.lls di. not demonstrate spec.fi.0}tumor targeti.g. i. summary, we report that targeted nano-c.ntrast agents （Syndec.n-MS-GNRs） c.n suc.essfully detec. orthotopi.0}panc.eati.0}tumors wi.h mi.i.um off-target bi.di.g i. vi.o usi.g MSOT.

关键词： multi.pec.ral optoac.usti.0}tomography panc.eati.0}c.nc.r syndec.n-1 mesoporous si.i.0} gold nanorods

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Exac. Ti.e-Dependent Wave Func.i.ns of a c.nfi.ed Ti.e-Dependent Harmoni.0}Osc.llator wi.h Two Movi.g Boundari.s

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c.mmuni.0}ti.ns i. Theoreti.0}l Physi.0} 2009年第11期52卷 820-824页

作者： c.F.Lo i.sti.ute of Theoreti.0}l Physi.0} and Department of Physi.0} The Chinese University of Hong Kong

By applyi.g the standard analyti.0}l tec.ni.ues of solvi.g parti.l di.ferenti.l equati.ns, we have obtai.ed the exac. soluti.n i. terms of the Fouri.r si.e seri.s to the ti.e-dependent Sc.rodi.ger equati.n desc.i.i.g a quantum one-di.ensi.nal harmoni.0}osc.llator of ti.e-dependent frequenc. c.nfi.ed i. an i.fi.i.e square well wi.h the two walls movi.g along some parametri.0}trajec.ori.s. Based upon the orthonormal basi. of quasi.stati.nary wave func.i.ns, the exac. propagator of the system has also been analyti.0}lly deri.ed. Spec.al eases li.e （i. a c.nfi.ed free parti.0}e, （i.） a c.nfi.ed ti.e-i.dependent harmoni.0}osc.llator, and （i.i. an agi.g osc.llator are exami.ed, and the c.rrespondi.g ti.e- dependent wave func.i.ns are expli.0}tly determi.ed. Besi.es, the approac. has been extended to solve the c.se of a c.nfi.ed generali.ed ti.e-dependent harmoni.0}osc.llator for some parametri.0}movi.g boundari.s as well.

关键词： i.fi.i.e square well harmoni.0}osc.llator movi.g boundari.s Fouri.r seri.s

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