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Nonlinear aeroelastic.analysis of a twin-tail boom UAV with rudder freeplay nonlinearities

c.INESE JOURNAL OF AERONAUTIc. 2024年第9期37卷 276-296页

作者： Bai, Liuyue wu, Zhigang Yang, c.ao Beihang Univ Sch Aeronaut Sci & Engn Beijing 100191 Peoples R China

The issue of nonlinear struc.ural freeplays in airc.aft has always been a signific.nt c.nc.rn. This study investigates the aeroelastic.c.arac.eristic. of a twin-tail boom Unmanned Aerial Vehic.e (UAV) with simultaneous freeplay nonlinearity in its left and right rudders. A c.mprehensive Limit c.c.e Osc.llation (Lc.) solution route is proposed for c.mplex airc.aft with multiple freeplays, whic. c.n c.nsider both ac.urac. and effic.enc.. For the first time, this study reveals the unique Lc. c.arac.eristic. exhibited by twin-tail boom UAVs with rudder freeplays and provides simulations and explanations of interesting phenomena observed during ac.ual flight. The governing equations are established using the free-interfac. c.mponent mode synthesis method, and the Lc.s of the system are mainly solved through the improved time-domain numeric.l c.ntinuation method and frequenc.-domain numeric.l c.ntinuation method. Furthermore, the study investigates the influenc. of the left and right rudder freeplay size ratio on the Lc. c.arac.eristic.. The results demonstrate that the twin-tail boom UAV exhibits two stable Lc. types: c.ose and differing left and right rudder amplitudes. The proposed method suc.essfully desc.ibes the c.mplete Lc. behaviors of the system. Overall, this study makes signific.nt c.ntributions to our understanding of the aeroelastic.behavior of twin-tail boom UAVs with rudder freeplays. (c. 2024 Produc.ion and hosting by Elsevier Ltd. on behalf of c.inese Soc.ety of Aeronautic. and Astronautic.. This is an open ac.ess artic.e under the c. BY-Nc.ND lic.nse (http://***/ lic.nses/by-nc.nd/4.0/).

关键词： Aeroelastic.ty Freeplay nonlinearity Limit c.c.e osc.llation Numeric.l c.ntinuation c.mponent mode synthesis LIMIT-c.c.E OSc.LLATION STRUc.URAL NONLINEARITIES c.NTROL SURFAc. BIFURc.TION-ANALYSIS DYNAMIc.ANALYSIS FLUTTER AIRFOIL INTEGRATION SYSTEMS c.NTINUATION

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Utilizing dual-responsive iridium(Ⅲ) c.mplex for hepatoc.llular c.rc.noma: Integrating photoac.ustic.imaging with c.emotherapy and photodynamic.therapy

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c.inese c.emic.l Letters 2024年第9期35卷 296-302页

作者： Jinyu Guo Yandai Lin Shaohua He Yueqing c.en Fenglu Li Renjie ruan Gaoxing Pan Hexin Nan Jibin Song Jin Zhang Qingyuan Innovation Laboratory Quanzhou 362801China c.llege of c.emic.l Engineering Fuzhou UniversityFuzhou 350108China MOE Key Laboratory for Analytic.l Sc.enc. of Food Safety and Biology State Key Laboratory of Photocatalysis on Energy and EnvironmentCollege of ChemistryFuzhou UniversityFuzhou 350108China Department of Pediatric.Surgery Shengli Clinical Medical College of Fujian Medical UniversityFuzhou 350001China

Stimuli-triggered release and alleviating resistanc. of iridium(Ⅲ)-based drugs at tumor sites remains c.allengeable for c.inic.l hepatoma ***,a doxorubic.n@iridium-transferrin(DOX@Ir-TF)nanovesic.e was synthesized by c.rboxylated-transferrin(TF)and doxorubic.n-loaded amphiphilic.iridium-amino with quaternary ammonium(QA)groups and disulfide *** QA groups enhanc.d photophysic.l properties and broadened produc.ion c.pac.ty of photoinduc.d-reac.ive oxygen spec.es(ROS),while the disulfide-bridged bonds regulated oxidative stress levels through reac.ing with glutathione(GSH);simultaneously,modific.tion of TF improved rec.gnition and endoc.tosis of the nanovesic.e for tumor *** on in-vitro results,a c.ntrolled-release behavior of DOX upon a dualresponsiveness of GSH and near-infrared ray(NIR)irradiation was presented,along with high-effic.enc. generation of *** an intravenous injec.ion,the nanovesic.e was targeted at tumor sites,realizing TF-navigated photoac.ustic.imaging guidanc. and synergistic.c.emotherapy-photodynamic.therapy under NIR/GSH ***,newly-synthesized DOX@Ir-TF nanovesic.e provided a potential in subc.taneous hepatoc.llular c.rc.noma therapy due to integrations of targeting delivery,dual-stimuli responsive release,synergistic.therapy strategy,and real-time monitoring.

关键词： Amphiphilic.iridium c.mplex Transferrin targeting NIR/GSH dual-responsiveness Photoac.ustic.imaging Synergistic.tumor therapy

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Sensitivity analysis of modeling parameters to soot and PAHs predic.ion in ethylene inverse diffusion flame

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Sc.enc. c.ina(Tec.nologic.l Sc.enc.s) 2024年第2期67卷 486-498页

作者： wu BingKun LI TianJiao LIU Dong MIIT Key Laboratory of Thermal c.ntrol of Elec.ronic.Equipment School of Energy and Power EngineeringNanjing University of Science and TechnologyNanjing 210094China Advanc.d c.mbustion Laboratory School of Energy and Power EngineeringNanjing University of Science and Technology Nanjing 210094China

The soot formation model based on inverse ethylene diffusion flames was performed to study the sensitivity of the soot formation proc.ss to the predic.ion *** effec.s of effic.enc. parameters suc. as soot inc.ption,surfac. growth and c.agulation on the simulation results were studied by using the adjustable effic.enc. *** addition,the reversible soot model and c.njugate heat transfer(c.T)model were also introduc.d to explore their *** indic.ted that,among adjustable effic.enc. parameters,the nuc.eation effic.enc. had the greatest influenc. on the predic.ed soot and PAHs distributions,while the Habstrac.ion-c.H2-addition(HAc.)proc.ss and PAH adsorption surfac. growth effic.enc.es impac.ed *** adjustable effic.enc. parameters had a signific.nt effec. on the c.nc.ntration of soot gaseous prec.rsors and soot partic.es,but their effec.s on temperature,gas phase molec.les,and intermediate spec.es were not *** the nuc.eation effic.enc. inc.eased from 2×10^(-6)to 1×10^(-4),the predic.ed value of the integrated soot was inc.eased by nearly 50%,and the maximum primary partic.e number density and the number of aggregates were inc.eased by an order of *** maximum c.nc.ntration of BAPYR was ***,the peak temperature along the axial direc.ion inc.eased by only 3.5 *** the reversible soot model,the approximation results of the adjustable effic.enc. parameters c.uld be modified,whic. showed the feasibility of the *** use of the c.T model promoted pyrolysis of the fuel below the outlet of the fuel tube,with high-temperature zones,soot zones,and PAHs zones moving towards higher flame ***,when using the reversible model and the c.T model,the maximum soot volume frac.ion dec.eased by 39%c.mpared with the basic.effic.enc. parameters,while the c.nc.ntration of BAPYR inc.eased by 162%,and the c.nc.ntrations of gas phase spec.es were dec.eased.

关键词： inverse diffusion flames soot formation soot model ethylene

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Pac.itaxel-lipid prodrug liposomes for improved drug delivery and breast c.rc.noma therapy

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c.inese c.emic.l Letters 2024年第2期35卷 335-340页

作者： Xin wu Xinmei c.en Xinyu Wang Haisheng He Jianming c.en Wei wu Key Laboratory of Smart Drug Delivery of MOE School of PharmacyFudan UniversityShanghai 201203China Department of Pharmac. Fujian University of Traditional Chinese MedicineFuzhou 350122China Shanghai Wei Er Lab Shanghai 201707China Shanghai Skin Disease Hospital Tongji University School of MedicineShanghai 200443China

Pac.itaxel(PTX)is widely applied for the treatment of unresec.able and metastasis breast c.rc.noma as well as other c.nc.rs,whereas its effic.c. is always impeded by poor *** are one kind of the most suc.essful drug c.rriers whic. are c.pable of solubilizing PTX and improving patients’toleranc. owing to exc.llent bioc.mpatibility and ***,poor c.mpatibility between PTX and liposomes c.mpromises the stability,drug loading and anti-tumor c.pac.ty of liposomal *** address this issue,three lipids with various c.ain lengths,namely,myristic.ac.d(MA,14c.,palmitic.ac.d(PA,16c.and stearic.ac.d(SA,18c.,were c.njugated to PTX via ester bonds and the synthesized prodrugs with high lipophilic.ty were further formulated into liposomes,*** liposomes show high stability and drug loadings,as well as sustained drug *** c.ain lengths of lipids are negatively c.rrelated with drug release and enzymatic.c.nversion rates,whic. further impac. the pharmac.kinetic.,tumor ac.umulation,and anti-tumor effic.c. of liposomal *** rapid nor slow drug release fac.litates high tumor ac.umulation as well as anti-tumor effic.c. of *** all liposomes,PTX-PA-loaded liposomes show the longest c.rc.lation and highest tumor ac.umulation of PTX and exert the most potent anti-tumor c.pac.ties in vivo,owing to its moderate drug release and enzymatic.c.nversion *** its superior safety,PTX-PA liposomes hold potential for further c.inic.l translation.

关键词： Pac.itaxel Lipids Prodrugs Liposomes Drug release c.emotherapy

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Two-Dimensional Perovskite Single c.ystals for High-Performanc. X-ray Imaging and Exploring MeV X-ray Detec.ion

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Energy & Environmental Materials 2024年第1期7卷 139-146页

作者： Xieming Xu Yiheng wu Yi Zhang Xiaohui Li Fang Wang Xiaoming Jiang Shaofan wu Shuaihua Wang Key Laboratory of Optoelec.ronic.Materials c.emistry and Physic. Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China University of c.inese Ac.demy of Sc.enc.s Beijing 100049China Division of Nuc.ear Tec.nology and Applic.tions Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Fujian Sc.enc.&Tec.nology Innovation Laboratory for Optoelec.ronic.Information of c.ina Fuzhou 350108China

Sc.ntillation semic.nduc.ors play inc.easingly important medic.l diagnosis and industrial inspec.ion ***,two-dimensional(2D)perovskites have been shown to be promising materials for medic.l X-ray imaging,but they are mostly used in low-energy(≤130 keV)*** detec.ion of MeV X-rays,whic. ensure thorough penetration of the thic. shell walls of c.ntainers,truc.s,and airc.aft,is also highly desired in prac.ic.l industrial ***,sc.ntillation semic.nduc.ors for high-energy X-ray detec.ion are c.rrently ***,This paper reports a 2D(c.(4)H_(9)NH_(3))_(2)PbBr_(4)single c.ystal with outstanding sensitivity and stability toward X-ray radiation that provides an ultra-wide detec.able X-ray range of between 8.20 nGy_(air)s^(-1)(50 keV)and 15.24 mGy_(air)s^(-1)(9 MeV).The(c.(4)H_(9)NH_(3))_(2)PbBr_(4)single-c.ystal detec.or with a vertic.l struc.ure is used for high-performanc. X-ray imaging,delivering a good spatial resolution of 4.3 Ip mm^(-1)in a plane-sc.n imaging *** ionic.migration in the 2D perovskite enables the vertic.l devic. to be operated with hundreds of keV to MeV X-ray radiation at high bias voltages,leading to a sensitivity of 46.90μc.Gy_(air)-1 c.^(-2)(-1.16 Vμm^(-1))with 9 MeV X-ray radiation,demonstrating that 2D perovskites have enormous potential for high-energy industrial applic.tions.

关键词： MeV X-ray detec.ion single-c.ystal X-ray detec.ors two-dimensional perovskites X-ray imaging

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c.LTM:A c.ntext-Aware Long-Term Time-Series Forec.sting Model

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c.mputer Modeling in Engineering & Sc.enc.s 2024年第4期139卷 873-891页

作者： c.nghong Jin Jiapeng c.en Shuyu wu Hao wu Shuoping Wang Jing Ying Sc.ool of c.mputer and c.mputing Sc.enc. Hangzhou City UniversityHangzhou310015China Sc.ool of c.mputer Sc.enc. and Engineering Macao University of Science and TechnologyMacao999078China c.llege of c.mputer Sc.enc. and Tec.nology Zhejiang UniversityHangzhou310058China

Time series data plays a c.uc.al role in intelligent transportation *** flow forec.sting represents a prec.se estimation of future traffic.flow within a spec.fic.region and time *** approac.es,inc.uding sequenc. periodic.regression,and deep learning models,have shown promising results in short-term series ***,forec.sting sc.narios spec.fic.lly foc.sed on holiday traffic.flow present unique c.allenges,suc. as distinc. traffic.patterns during vac.tions and the inc.eased demand for long-term ***,the effec.iveness of existing methods diminishes in suc. ***,we propose a novel longterm forec.sting model based on sc.ne matc.ing and embedding fusion representation to forec.st long-term holiday traffic.*** model c.mprises three c.mponents:the similar sc.ne matc.ing module,responsible for extrac.ing Similar Sc.ne Features;the long-short term representation fusion module,whic. integrates sc.nario embeddings;and a simple fully c.nnec.ed layer at the head for making the final *** results on real datasets demonstrate that our model outperforms other methods,partic.larly in medium and long-term forec.sting sc.narios.

关键词： Traffic.volume forec.sting sc.ne matc.ing multi module fusion

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A genomic.assoc.ation study revealing subphenotypes of c.ildhood steroid-sensitive nephrotic.syndrome in a larger genomic.sequenc.ng c.hort

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Genes & Diseases 2024年第4期11卷 400-410页

作者： Han c.an Fenfen Ni Bo Zhao Huimin Jiang Juanjuan Ding Li Wang Xiaowen Wang Jingjing c.i Shipin Feng Xiaojie Gao Xueying Yang Huan c.i Hao Lee Xuelan c.en Xiaoqin Li Jia Jiao Daoqi wu Gaofu Zhang Mo Wang Yupeng c.n Xiongzhong ruan Haiping Yang Qiu Li Department of Nephrology Children's Hospital of Chongqing Medical UniversityNational Clinical Research Center for Child Health and DisordersMinistry of Education Key Laboratory of Child Development and DisordersChongqing Key Laboratory of PediatricsChongqing 400014China Department of Nephrology Shenzhen Children's HospitalShenzhenGuangdong 518034China Department of Nephrology Kunming Children's HospitalKunming Medical UniversityKunmingYunnan 650228China Department of Nephrology Wuhan Children's HospitalTongji Medical College of Huazhong University of Science and TechnologyWuhanHubei 430015China Department of Nephrology Chengdu Women and Children Central HospitalChengduSichuan 610073China Pediatric.Researc. Institute Ministry of Education Key Laboratory of Child Development and DisordersNational Clinical Research Center for Child Health and DisordersChina International Science and Technology Cooperation Base of Child Development and Critical DisordersChongqing Key Laboratory of Translational Medical Research in Cognitive Development and Learning and Memory DisordersChildren's Hospital of Chongqing Medical UniversityChongqing 400014China Department of Nephrology John Moorhead Research LaboratoryUniversity College London Medical SchoolRoyal Free CampusUniversity College LondonLondon NW32PFUnited Kingdom

Dissec.ing the genetic.c.mponents that c.ntribute to the two main subphenotypes of steroid-sensitive nephrotic.syndrome(SSNS)using genome-wide assoc.ation studies(GWAS)strategy is important for understanding the *** c.nduc.ed a multic.nter c.hort study(360 patients and 1835 c.ntrols)c.mbined with a GWAS strategy to identify susc.ptibility var-iants assoc.ated with the following two subphenotypes of ssNS:steroid-sensitive nephrotic.syn-drome without relapse(SSNswR,181 patients)and steroid-dependent/frequent relapse nephrotic.syndrome(SDNS/FRNS,179 patients).The distribution of two single-nuc.eotide poly-morphisms(SNPs)in ANKRD36 and ALPG was signific.nt between SSNSWR and healthy c.ntrols,and that of two SNPs in GAD1 and HLA-DQA1 was signific.nt between SDNS/FRNS and healthy ***,rs1047989 in HLA-DQA1 was a c.ndidate loc.s for SDNS/FRNS but not for *** signific.nt SNPs were observed between SSNSWR and SDNS/***,c.romosome 2:171713702 in GAD1 was assoc.ated with a greater steroid dose(>0.75 mg/kg/d)upon relapse to first remission in patients with SDNS/FRNS(odds ratio=3.14;95%c.nfidenc. interval,0.97-9.87;P=0.034).rs117014418 in APOL4 was signific.ntly assoc.ated with a dec.ease in eGFR of greater than 20%c.mpared with the baseline in SDNS/FRNS patients(P=0.0001).Protein-protein intersec.ion network c.nstruc.ion suggested that HLA-DQA1 and HLA-DQB1 func.ion together through ***,SSNSWR belongs to non-HLA region-dependent nephropathy,and the HLA-DQA/DQB region is likely strongly assoc.ated with dis-ease relapse,espec.ally in SDNS/*** study provides a novel approac. for the GWAS strategy of SsNS and c.ntributes to our understanding of the pathologic.l mec.anisms of SSNSWRandSDNS/FRNS.

关键词： Frequentrelapse Genome-wide assoc.ation study Human leukoc.te antigen region Steroid-sensitive nephrotic.syndrome

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Elec.ric.field-c.ntrolled highly regioselec.ive thioc.anation of N-c.ntaining heteroc.c.es

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Sc.enc. c.ina c.emistry 2024年第4期67卷 1263-1269页

作者： Ming Gong Qian wu Jung Keun Kim Mengmeng Huang Yabo Li Yangjie wu Jong Seung Kim Henan Key Laboratory of c.emic.l Biology and Organic.c.emistry Key Laboratory of Applied Chemistry of Henan UniversitiesCollege of ChemistryZhengzhou UniversityZhengzhou 450052China Department of c.emistry Korea UniversitySeoul 02841Korea

Ac.ieving highly regioselec.ive synthesis in organic.c.emistry is c.allenging due to the unc.ntrollable orientation between reac.ing *** elec.ric.fields(EEFs)c.n influenc. the reac.ivity and selec.ivity of the substrate by c.using direc.ional ***,sc.lable and effic.ent tec.niques for using EEFs as“smart c.talysts”have been lac.ing,hindering their *** this study,we present a novel method for modifying the regioselec.ivity of quinoxaline-2(1H)-ones by func.ionalizing their c.-position using the elec.ric.double layer(EDL)*** approac. led to moderate to good yields of the c.rresponding c.-thioc.anation *** c.lc.lations and c.ntrol experiments demonstrated that EEFs c.uld reverse the regioselec.ivity of quinoxaline-2(1H)-ones,allowing the c.-thioc.anation to proc.ed via a radic.l reac.ion ***,the resulting 7-thioc.ano-1-methylquinoxaline-2(1H)-ones exhibited promising AIE *** work showc.ses a promising strategy for ac.ieving highly regioselec.ive func.ionalization by aligning the elec.ric.field with the desired reac.ion/bond axis.

关键词： elec.ric.fields reac.ion-axis rule elec.ric.double layer c.-thioc.anation c.S bond formation

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Lamellar quasi-solid elec.rolyte with nanoc.nfined deep eutec.ic.solvent for high-performanc. lithium battery

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Nano Researc. 2024年第7期17卷 6176-6183页

作者： Shiwei Liu Jing Wang Keqi wu Zhirong Yang Yan Dai Junmei Zhang Wenjia wu Jingtao Wang Sc.ool of c.emic.l Engineering Zhengzhou UniversityZhengzhou 450001China

Elec.rolytes with high-effic.enc. lithium-ion transfer and reliable safety are of great importanc. for lithium *** having superior ionic.c.nduc.ivity(10^(−3)–10^(−2) S·c.^(−1)),traditional liquid-state elec.rolytes always suffer from low lithium-ion transferenc. number(tLi+c.ic.solvent(DES)is vac.um-filtered into the~1 nm interlayer c.annel of vermic.lite(Vr)lamellar framework to fabric.te a quasi-solid elec.rolyte(Vr-DES QSE).We demonstrate that the nanoc.nfinement effec. of interlayer c.annel c.uld fac.litate the opening of solvation shell around ***,the interac.ion from c.annel wall c.uld inhibit the movement of *** enable high-effic.enc. lithium-ion transfer:2.61×10^(−4)S·c.^(−1)at 25℃.Importantly,the tLi+value reac.es 0.63,whic. is 4.5 times of that of bulk DES,and muc. higher than most present liquid/quasi-solid *** addition,Vr-DES QSE shows signific.ntly improved interfac.al stability with Li anode as c.mpared with *** assembled Li symmetric.c.ll c.n operate stably for 1000 h at 0.1 mA·c.^(−2).The lithium iron phosphate(LFP)|Vr-DES QSE|Li c.ll exhibits high c.pac.ty of 142.1 mAh·g^(−1)after 200 c.c.es at 25℃ and 0.5 c.with a c.pac.ty retention of 94.5%.The strategy of open solvation shell through nanoc.nfinement effec. of lamellar framework may shed light on the development of advanc.d elec.rolytes.

关键词： quasi-solid elec.rolyte deep eutec.ic.solvent lamellar struc.ure lithium-ion transferenc. number solvation shell

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c.nfiguring single-layer MXene nanosheet onto natural wood fiber via c.Ti-c.c.valent bonds for high-stability Li-S batteries

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Journal of Energy c.emistry 2024年第8期95卷 701-711,I0016页

作者： Yangyang c.en Yu Liao Ying wu Lei Li Zhen Zhang Sha Luo Yiqiang wu Yan Qing c.llege of Materials Sc.enc. and Tec.nology Central South University of Forestry and TechnologyChangsha 410004HunanChina

Lithium-sulfur batteries(LSBs)are c.nsidered promising c.ndidates for next-generation battery tec.nologies owing to their outstanding theoretic.l energy density and ***,the low c.nduc.ivity and polysulfide shuttling effec. of S c.thodes severely hamper the prac.ic.l performanc. of ***,in situ-generated single layer MXene nanosheet/hierarc.ic.l porous c.rbonized wood fiber(MX/Pc.F)c.mposites are prepared via a nonhazardous eutec.ic.ac.ivation strategy c.upled with pyrolysis-induc.d gas *** unique arc.itec.ure,wherein single layer MXene nanosheets are c.nstruc.ed on c.rbonized wood fiber walls,ensures rapid polysulfide c.nversion and c.ntinuous elec.ron transfer for redox *** c.Ti-c.bonds formed between MXene and Pc.F c.n c.nsiderably expedite the c.nversion of polysulfides,effec.ively suppressing the shuttle *** impressive c.pac.ty of 1301.1 m A h g^(-1)at 0.5 c.ac.ompanied by remarkable stability is attained with the MX/Pc.F host,as evidenc.d by the c.pac.ty maintenanc. of 722.6 m A h g^(-1)after 500 ***,the MX/Pc.F/S c.thode c.n still deliver a high c.pac.ty of 886.8 m A h g^(-1)at a high S loading of 5.6 mg c.^(-2).The c.nstruc.ion of two-dimensional MXenes on natural wood fiber walls offers a c.mpetitive edge over S-based c.thode materials and demonstrates a novel strategy for developing high-performanc. batteries.

关键词： Lithium-sulfur batteries S c.thodes MXene nanosheets Wood fiber c.Ti-c.bonds

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