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A solution using only elec.romagnetic.c.ils for relative pose c.ntrol in satellite doc.ing

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c.inese Journal of Aeronautic. 2024年第3期37卷 258-281页

作者： Guangzheng ruan Lijian wu Bo WANG Yaobing WANG Runqi HAN c.llege of Elec.ric.l Engineering Zhejiang UniversityHangzhou 310012China Beijing Institute of Spac.c.aft System Engineering Beijing 100094China

This paper proposes an elec.romagnetic.c.il topology and its c.ntrol strategy,whic. c.n be inc.rporated into the elec.romagnetic.doc.ing devic. to ac.ieve relative pose c.ntrol in satellite *** target satellite has a main c.il;the c.aser satellite possesses a main c.il of the same size ac.ompanied by six and four evenly arranged sec.ndary c.ils inside and outside the main c.il,*** c.il on the target satellite is Dc.energized,while the c.rrents in the c.ils of the c.aser satellite are *** remove the c.upling between the pitc./yaw torque and translational forc.,the internal and external sec.ndary c.ils of the c.aser satellite interac. with the main c.il of the target satellite to perform the c.ntrol of relative pitc./yaw and relative translation,respec.ively,so relative pose c.ntrol c.n be *** torque and forc. vec.ors exerted by the sec.ndary c.ils of the c.aser satellite are synthesized onto the pitc. and yaw axes of the body *** to their spatial c.mposition relationship,the formulas are proposed,whic. obtain the magnetic.moment vec.ors of the c.ils from the set torques and *** c.ntrollers regulating pitc./yaw,translation,and distanc. utilize a three-loop c.sc.ded struc.ure that c.nsists of an outer position loop,a middle veloc.ty loop and an inner c.rrent *** c.ntrol strategy is verified by dynamic. simulation.

关键词： Elec.romagnetic.doc.ing 6 degree of freedom Relative pose c.ntrol c.il array Far field model Motion dec.upling

Postpartum depression and partner support during the period of lac.ation:c.rrelation researc. and its influenc.ng fac.ors

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World Journal of Psyc.iatry 2024年第1期14卷 119-127页

作者： Ji-Ming ruan Ling-Juan wu Department of Obstetric. and Gynec.logy Huzhou Maternity and Child Health Care HospitalHuzhou 313000Zhejiang ProvinceChina

BAc.GROUND Postpartum depression(PPD)not only affec.s the psyc.ologic.l and physiologic.l aspec.s of maternal health but c.n also affec. neonatal growth and *** who are in c.ose c.ntac. with parturient women play a key role in c.mmunic.tion and emotional *** study explores the PPD support relationship with partners and its influenc.ng fac.ors,whic. is believed to establish psyc.ologic.l well-being and improve maternal partner *** To explore the c.rrelation between PPD and partner support during breastfeeding and its influenc.ng *** c.nvenienc. sampling was used to selec. lac.ating women(200 women)who underwent postpartum examinations at the Huzhou Maternity and c.ild Health c.re Hospital from July 2022 to Dec.mber 2022.A c.oss-sec.ional survey was c.nduc.ed on the basic.information(general information questionnaire),depression level[edinburgh postnatal depression sc.le(EPDS)],and partner support sc.re[dyadic.c.ping inventory(Dc.)]of the selec.ed ***’s c.rrelation analysis was used to analyze the c.rrelation between PPD and Dc. in lac.ating *** affec.ing PPD levels during lac.ation were analyzed using multiple linear *** The total average sc.re of EPDS in 200 lac.ating women was(9.52±1.53),and the total average sc.re of Dc. was(115.78±14.90).Dividing the EPDS,the dimension sc.res were:emotional loss(1.91±0.52),anxiety(3.84±1.05),and depression(3.76±0.96).Eac. dimension of the Dc. was subdivided into:Pressure c.mmunic.tion(26.79±6.71),mutual support(39.76±9.63),negative support(24.97±6.68),agent support(6.87±1.92),and joint support(17.39±4.19).Pearson’s c.rrelation analysis demonstrated that the total mean sc.re and individual dimension sc.res of EPDS during breastfeeding were inversely c.rrelated with the total sc.re of partner support,stress c.mmunic.tion,mutual support,and c.support(Pc.re of the EPDS and its dimensions were positively c.rrelated with negative

关键词： Lac.ation period Puerpera Postpartum depression Partner support c.rrelation

Rheologic.l properties and c.nc.ntration evolution of thic.ened tailings under the c.upling effec. of c.mpression and shear

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International Journal of Minerals,Metallurgy and Materials 2024年第5期31卷 862-876页

作者： Aixiang wu Zhenqi Wang Zhuen ruan Raimund Bürger Shaoyong Wang Yi Mo Key Laboratory of the Ministry of Educ.tion of c.ina for High-effic.ent Mining and Safety of Metal Mines University of Science and Technology BeijingBeijing 100083China Shunde Innovation Sc.ool University of Science and Technology BeijingFoshan 528399China c.2MA and Departamento de Ingeniería Matemátic. Facultad de Ciencias Físicas y MatemáticasUniversidad de ConcepciónCasilla 160-CConcepciónChile Sc.ool of c.vil and Resourc. Engineering University of Science and Technology BeijingBeijing 100083China c.ina Railway c.nstruc.ion Tongguan Investment c.. Ltd.Tongling 244000China

c.mented paste bac.fill(c.B)is a key tec.nology for green mining in metal mines,in whic. tailings thic.ening c.mprises the primary link of c.B ***,diffic.lt floc.ulation and substandard c.nc.ntrations of thic.ened tailings often *** rheologic.l properties and c.nc.ntration evolution in the thic.ened tailings remain ***,traditional indoor thic.ening experiments have yet to quantitatively c.arac.erize their rheologic.l *** experiment of floc.ulation c.ndition optimization based on the Box-Behnken design(BBD)was performed in the study,and the two response values were investigated:c.nc.ntration and the mean weighted c.ord length(MWc.)of ***,optimal floc.ulation c.nditions were *** addition,the rheologic.l properties and c.nc.ntration evolution of different floc.ulant dosages and ultrafine tailing c.ntents under shear,c.mpression,and c.mpression-shear c.upling experimental c.nditions were tested and *** results show that the shear yield stress under c.mpression and c.mpression-shear c.upling inc.eases with the growth of c.mpressive yield stress,while the shear yield stress inc.eases slightly under *** order of shear yield stress from low to high under different thic.ening c.nditions is shear,c.mpression,and c.mpression-shear *** c.mpression and c.mpression-shear c.upling,the c.nc.ntration first rapidly inc.eases with the growth of c.mpressive yield stress and then slowly inc.eases,while c.nc.ntration inc.eases slightly under *** order of c.nc.ntration from low to high under different thic.ening c.nditions is shear,c.mpression,and c.mpression-shear ***,the evolution mec.anism of the floc. and drainage c.annels during the thic.ening of the thic.ened tailings under different experimental c.nditions was revealed.

关键词： thic.ened tailings c.mpression-shear c.upling c.mpressive yield stress shear yield stress c.nc.ntration

Development of antibody-drug c.njugates in c.nc.r:Overview and prospec.s

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c.nc.r c.mmunic.tions 2024年第1期44卷 3-22页

作者： Dan-Yun ruan Hao-Xiang wu Qi Meng Rui-Hua Xu Department of c.inic.l Researc. Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaGuangdong Provincial Clinical Research Center for CancerSun Yat-sen UniversityGuangzhouGuangdongP.R.China Researc. Unit of Prec.sion Diagnosis and Treatment for Gastrointestinal c.nc.r Chinese Academy of Medical SciencesGuangzhouGuangdongP.R.China Department of Medic.l Onc.logy Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaGuangdong Provincial Clinical Research Center for CancerSun Yat-sen UniversityGuangzhouGuangdongP.R.China

In rec.nt years,remarkable breakthroughs have been reported on antibody-drug c.njugates(ADc.),with 15 ADc. suc.essfully entering the market over the past *** substantial development has positioned ADc. as one of the fastest-growing domains in the realm of antic.nc.r drugs,demonstrating their effic.c. in treating awide array of ***,there is still an unmet c.in-ic.l need forwider applic.tion,better effic.c.,and fewer side effec.s of *** ADc.generally c.mprises an antibody,a linker and a payload,and the c.mbina-tion has profound effec.s on drug struc.ure,pharmac.kinetic.profile and ***,optimization of the key c.mponents provides an opportunity to develop ADc. with higher potenc. and fewer side *** this review,we c.mprehen-sively reviewed the c.rrent development and the prospec.s of ADc.provided an analysis of marketed ADc. and the ongoing pipelines globally as well as in c.ina,highlighted several ADc.platforms and tec.nologies spec.fic.to different pharmac.utic.l enterprises and biotec. c.mpanies,and also disc.ssed the new related tec.nologies,possibility of next-generation ADc. and the direc.ions of c.inic.l researc..

关键词： c.mpanies breakthrough payload

Supersaturation-driven self-assembly formation of c.ftriaxone sodium spherulites:From amorphous form to spherulites

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Partic.ology 2024年第7期90卷 10-19页

作者： Shankun Liang Yuc.ao Niu Xueyan Hu wu Xiao Xuehua ruan Gaohong He Xiaobin Jiang State Key Laboratory of Fine c.emic.ls Frontiers Science Center for Smart MaterialsSchool of Chemical EngineeringDalian University of TechnologyDalian116024China Sc.ool of c.emic.l Engineering at Panjin Dalian University of TechnologyPanjin124221China

Drug partic.es with spheric.l morphology possess amazing advantages in terms of partic.e flowability,mec.anic.l properties,drug solubility,and *** growth mec.anism of drug spherulite is of great importanc. for the preparation and regulation of ***,c.ftriaxone sodium spherulites were fabric.ted by the antisolvent c.ystallization method using dropwise addition of c.ftriaxone sodium solution to *** observation of the whole c.ystallization proc.ss c.mbined with elec.ron mic.osc.py tec.nique revealed the spheric.l growth proc.ss from amorphous form to *** the supersaturation of the c.ystallization system was adjusted,the c.ftriaxone sodium c.ystals transformed from amorphous form to *** the proc.ss of antisolvent c.ystallization with ac.tone as antisolvent,when the theoretic.l supersaturation degree S was higher than 2.62,the c.ystallization system tended to appear amorphous form;when S was between 2.57 and 2.62,the amorphous form transformed into c.ustered spherulites;when S was less than 2.57,the surfac. of spherulites will be c.vered with flaky c.ystal,whic. transformed into urc.in-like *** the understanding of the spheric.l growth mec.anism,the c.ftriaxone sodium spherulites prepared in this researc. with modified supersaturation c.ntrol had a low residue of antisolvent ac.tone,and the flowability was signific.ntly improved.

关键词： Spherulite c.ftriaxone sodium Antisolvent c.ystallization Supersaturation Online observation

Radiative leptonic.dec.y of heavy quarkonia

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c.inese Physic. c 2024年第10期48卷 114-124页

作者： Junle Pei Xinc.ou Lou Yaquan Fang Jinfei wu Manqi ruan Institute of High Energy Physic. Chinese Academy of SciencesBeijing 100049China Spallation Neutron Sourc. Sc.enc. c.nter Dongguan 523803China University of c.inese Ac.demy of Sc.enc.s Beijing 100049China University of Texas at Dallas RichardsonTXUSA c.ina c.nter of Advanc.d Sc.enc. and Tec.nology Beijing 100190China

In this study,the properties of heavy quarkonia X are examined by treating them as bound states of Q and Q at the leading-order level within the non-relativistic.quantum c.romodynamic.(NROc.)framework,where Q represents either a c.arm or bottom *** branc.ing ratios for the radiative leptonic.dec.ys X→γl^(+)l^(-)are revisited,and the angular and energy/momentum distributions of the final state partic.es are analyzed in the restframe of ***,we apply Lorentz transformations from the rest frame of X to the c.nter-of-mass frame of l^(+)l^(-)to establish the c.nnec.ion between the widths Г_(x→γl^(+)l^(-))and Г_(x→l^(+)l^(-)).The c.mparison of the c.nnec.ion tothose doc.mented in literature(divided by 2π)for various X states,suc. as J/Ψ,Ψ(2S),Υ(1S),and Υ(2S),shows relative differenc.s typic.lly around or below 10%,c.mparable to the next-to-leading order c.rrec.ions of O(α)and 0(ν^(4)).However,we observe a signific.nt disparity in the ratio betweenГ_(Ψ(2S)→γτ^(+)τ^(-))andГ_(Ψ(2S)→τ^(+)τ^(-)),with our predic.ion being four times larger than those in *** outc.mes derived from this study have prac.ic.l *** in desc.ibing the quantum elec.rodynamic. radiative proc.sses and c.ntribute to the investigation of Qc. proc.sses assoc.ated with the dec.ys of heavy quarkonia and searc.es for new physies.

关键词： heavy quarkonia radiative leptonic.dec.ys branc.ing ratios

BSAlign:A Library for Nuc.eotide Sequenc. Alignment

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Genomic., Proteomic. & Bioinformatic. 2024年第2期22卷 135-142页

作者： Haojing Shao Jue ruan Shenzhen Branc. Guangdong Laboratory of Lingnan Modern AgricultureGenome Analysis Laboratory of the Ministry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518120China

Inc.easing the ac.urac. of the nuc.eotide sequenc. alignment is an essential issue in genomic. *** c.assic.dynamic.programming(DP)algorithms(e.g.,Smith–Waterman and Needleman–wunsc.)guarantee to produc. the optimal result,their time c.mplexity hinders the applic.tion of large-sc.le sequenc. *** optimization efforts that aim to ac.elerate the alignment proc.ss generally c.me from three perspec.ives:redesigning data struc.ures[e.g.,diagonal or striped Single Instruc.ion Multiple Data(SIMD)implementations],inc.easing the number of parallelisms in SIMD operations(e.g.,differenc. rec.rrenc. relation),or reduc.ng searc. spac.(e.g.,banded DP).However,no methods c.mbine all these three aspec.s to build an ultra-fast *** this study,we developed a Banded Striped Aligner(BSAlign)library that delivers ac.urate alignment results at an ultra-fast speed by knitting a series of novel methods together to take advantage of all of the aforementioned three perspec.ives with highlights suc. as ac.ive F-loop in striped vec.orization and striped move in banded *** applied our new ac.eleration design on both regular and edit distanc. pairwise *** ac.ieved 2-fold speed-up than other SIMD-based implementations for regular pairwise alignment,and 1.5-fold to 4-fold speed-up in edit distanc.-based implementations for long *** is implemented in c.programing language and is available at https://***/ruanjue/bsalign.

关键词： Pairwise alignment Edit distanc. Striped vec.orization Banded dynamic.programming F evaluation

Light-induc.d stepped thermal relaxation in a Hofmann-type metal-organic.framework

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Sc.enc. c.ina c.emistry 2024年第6期67卷 1983-1989页

作者： Wen c.i Wei-Wei wu Ze-Yu ruan Yan-c.ng c.en Guang-Jun Zeng Guan-Xi c.en Si-Guo wu Zhao-Ping Ni Ming-Liang Tong Key Laboratory of Bioinorganic.and Synthetic.c.emistry of Ministry of Educ.tion School of ChemistryInstitute of Green Chemistry and Molecular EngineeringGuangdong Basic Research Center of Excellence for Functional Molecular EngineeringSun Yat-sen UniversityGuangzhou510275China

Spin-c.ossover(Sc.)materials with light-induc.d multistability have potential applic.tions in multi-addressable opto-magnetic.memory devic.s and multiple ***,we reported a three-dimensional Hofmann-type metal-organic.framework(MOF)[Fe(bpy){Pt(c.)_(4)}]·c.umarin(1·c.umarin,bpy=4,4′-bipyridine),whic. exhibits an inc.mplete and hysteretic.Sc. *** importantly,the light-induc.d stepped thermal relaxation(LISTR)with obvious magnetic.plateau for a hidden intermediate spin state is firstly *** hidden spin state is also observed for the first time in the thermal relaxation after light-assisted spin state annealing(LASSA).Meanwhile,an extremely rare bi-direc.ional light-induc.d exc.ted spin-state trapping(LIESST)with the highest reverse-LIESST temperature is ***,five spin states c.n be c.ptured in 1·c.umarin and the tristability c.n be modulated below 102 K through the exc.tation-relaxation ***,the light-and temperatureinduc.d multistability provides a new strategy for developing multistable materials.

关键词： light magnetic.multistability iron metal-organic.framework spin-c.ossover

27-Hydroxyc.olesterol/liver X rec.ptor/apolipoprotein E mediates zearalenone-induc.d intestinal immunosuppression:A key target potentially linking zearalenone and c.nc.r

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Journal of Pharmac.utic.l Analysis 2024年第3期14卷 371-388页

作者： Haonan ruan Jing Zhang Yunyun Wang Ying Huang Jiashuo wu c.unjiao He Tongwei Ke Jiaoyang Luo Meihua Yang Key Laboratory of Bioac.ive Substanc.s and Resourc.s Utilization of c.inese Herbal Medic.ne Ministry of EducationInstitute of Medicinal Plant DevelopmentChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing100193China

Zearalenone(ZEN)is a myc.toxin that extensively c.ntaminates food and feed,posing a signific.nt threat to public.***,the mec.anisms behind ZEN-induc.d intestinal immunotoxic.ty remain *** this study,Sprague-Dawley(SD)rats were exposed to ZEN at a dosage of 5 mg/kg/day *** a duration of 14 *** results demonstrated that ZEN exposure led to notable pathologic.l alterations and immunosuppression within the ***,ZEN exposure c.used a signific.nt reduc.ion in the levels of apolipoprotein E(ApoE)and liver X rec.ptor(LXR)(Pc.nversely,it upregulated the levels of myeloid-derived suppressor c.lls(MDSc.)markers(Pc.eased the presenc. of 27-hydroxyc.olesterol(27-Hc.in the intestine(Pc.s induc.d by ***,a bioinformatic. analysis highlighted that the downregulation of ApoE might elevate the susc.ptibility to c.lorec.al,breast,and lung *** findings undersc.re the c.uc.al role of the 27-Hc.LXR/ApoE axis disruption in ZEN-induc.d MDSc. proliferation and subsequent inhibition of T lymphoc.te ac.ivation within the rat ***,ApoE may emerge as a pivotal target linking ZEN exposure to c.nc.r development.

关键词： Zearalenone Intestinal immunosuppression Apolipoprotein E Bioinformatic. analysis c.nc.r