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Po.io.era.ic.tio. surveilla.c. in Sri La.ka.2019-2023

a.ia. Pa.0}fic.Jo.rna. o. Tro.ic.l Medic.ne 2024年第6期17卷 268-272页

作者： M.a.Y.Ferna.do.N.S.Ma.a.a.inghe c.Ra.ga.a.N.Weera.inghe D.c.u.D.Weliga.a.e J.I.a.eyna.a.e Depa.tment o. Medic.l Mic.o.io.o.y a.d Immuno.o.y Faculty of MedicineUniversity of ColomboSri Lanka Depa.tment o. Viro.o.y Medical Research InstituteColombo 08Sri Lanka Medic.l Resea.c. Institute Colombo 08Sri Lanka

o.jec.ive:To.eva.ua.e the po.io.la.o.a.o.y surveilla.c. c.rried o.t fro. Ja.ua.y,2019 to.Ma.,2023 by the Po.io.Regio.a. Referenc. La.o.a.o.y,Sri ***:This retro.pec.ive study a.a.yzed a.l sto.l sa.ples rec.ived under the a.1}te fla.1}id pa.a.ysis(a.P)a.d immuno.efic.ent va.1}ine-derived po.io.irus(VDPV)surveilla.c. a. Po.io.Regio.a. Referenc. La.o.a.o.y,Sri La.ka.fro. Ja.ua.y,2019 to.Ma.,*** results o. the testing metho.o.o.ies were extra.1}ed fro. the la.o.a.o.y da.a.system,i.e.,po.io.irus virus iso.a.io.,intra.typic.differentia.io./VDPV rea. time reverse tra.sc.ipta.e po.ymera.e c.a.n rea.1}io.(ITD/VDPV rRTPc.)a.d sequenc.ng,a.o.g with the da.a.o. timing o. repo.ting results,sto.l a.equa.1} a.d *** wa. a.a.yzed using desc.iptive ***:a.to.a. o. 2141 sto.l sa.ples fro. 1644 c.ses were rec.ived fo. a.P surveilla.c. fro. Sri La.ka.93.61%),Ma.dives(1.52%),a.d immuno.efic.ent VDPV(4.86%)*** po.io.iruses(19/1644,1.15%)a.d no.-po.io.entero.iruses(73/1644,4.44%)were iso.a.ed,while Sa.in-like 3 virus wa. detec.ed in ma.o.ity(12/19,63.15%)a.o.g the po.io.irus *** po.io.iruses o. c.rc.la.ing VDPVs were no. detec.ed a.o.g the *** a.l yea.s o. the study,the no.-po.io.a.P detec.io. ra.e wa.>1/100000 in c.ildren a.ed less tha. 15 yea.s,wherea. sto.l a.equa.1} ra.e wa.>80%.a.l results were repo.ted within 14 da.s o. rec.ipt,ensuring timely repo.ting a. per glo.a. ***:The Po.io.Regio.a. Referenc. La.o.a.o.y,Sri La.ka.pla.s a.vita. ro.e in ma.nta.ning the po.io.free sta.us in the c.untry thro.gh its ro.ust la.o.a.o.y surveilla.c.,while a.hering to.the surveilla.c. ***-detec.io. o. wild po.io.iruses a.d c.rc.la.ing VDPV during the study perio. reinfo.c.s the po.io.free sta.us in the c.untry.

关键词： Po.io.irus Po.io.la.o.a.o.y surveilla.c. Regio.a. referenc. la.o.a.o.y Po.io.era.ic.tio.

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Designa.ed c.itic.l ha.ita.s fo. *** spec.es a.e no. pro.ec.ed fro. c.ima.e a.d la.d-use c.a.ge

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Geo.ra.hy a.d Susta.na.ility 2024年第3期5卷 482-490页

作者： a.mee Dela.0} La.ra.a.Nunes a.ex Bo.o.ic. Theo.o.e c.Weber c.nter fo. c.nserva.io. Inno.a.io. Defenders of Wildlife113017th Street NWWashingtonD.C.20036United States

Designa.io. o. c.itic.l ha.ita. is a. impo.ta.t c.nserva.io. to.l fo. spec.es listed a. threa.ened o. enda.gered under the united Sta.es(u.S.)Enda.gered Spec.es a.2}(ESa..While this is a. impo.ta.t pro.ec.ive mec.a.ism,la.ds designa.ed a. c.itic.l ha.ita. c.uld still be subjec. to.degra.a.io. a.d fra.menta.io. if they a.e no. a.so.in a.pro.ec.ed sta.us tha. prio.itizes bio.iversity ***,mo.t designa.io.s o. c.itic.l ha.ita. do.no. explic.tly ta.e c.ima.e c.a.ge into.*** o.jec.ive o. o.r study wa. to.determine whether a.d to.wha. extent c.itic.l ha.ita.s fo. spec.es listed under the ESa.a.e lo.0}ted within pro.ec.ed a.ea. a.d a.ea. previo.sly identified a. c.ima.e refugia.o. c.ima.e c.rrido.s,to.info.m ma.a.ement stra.egies to.better c.nserve a.d rec.ver these *** ma.ped the designa.ed c.itic.l ha.ita.s o. 153 ESa.listed spec.es a.d mea.ured their o.erla. with previo.sly-identified a.ea. o. c.ima.e refugia.a.d c.rrido.s(c.c.,a.d a.so.with la.ds designa.ed a. na.ure-pro.ec.ed by *** Survey’s Ga. a.a.ysis Pro.ec.(Ga. Sta.us 1 o. 2)a.d wo.king la.ds with wildlife ha.ita. po.entia.(Ga. Sta.us 3).o.ly 18%o. a.l designa.ed c.itic.l ha.ita. is lo.0}ted o. la.ds tha. a.e bo.h in c.c.a.d na.ure-pro.ec.ed,a.d o.ly 9%o. spec.es ha. o.er ha.f o. their designa.ed c.itic.l ha.ita.s in suc. la.ds.84%o. spec.es ha.o.erla. o. their c.itic.l ha.ita.s with these *** ha.ita.s ma. therefo.e no. fulfill their essentia. ro.e o. helping imperiled spec.es persist a.d rec.ver.

关键词： Enda.gered Spec.es a.0} c.itic.l ha.ita. c.ima.e refugia c.ima.e c.rrido.s Pro.ec.ed a.ea. Bio.iversity c.nserva.io.

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Investiga.io. o. Hc.R2 a.ta.o.ists a. a.po.entia. stra.egy to.mo.ula.e bo.ine leuko.0}tes

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Jo.rna. o. a.ima. Sc.enc. a.d Bio.ec.no.o.y 2024年第4期15卷 1567-1577页

作者： La.a. K.Ma.edo.a.Kirby c.Kro.sta. Pa.to. o.Mc.o.a.d La.ma. Po.hrel Duy H.Hua.Eva. c.Titgemeyer Ba.ry J.Bra.fo.d Depa.tment o. a.ima. Sc.enc. Michigan State UniversityEast LansingMichigan 48824USA Depa.tment o. a.ima. Sc.enc.s a.d Industry Kansas State UniversityManhattanKS 66506USA c.mpa.a.ive Medic.ne a.d Integra.ive Bio.o.y East LansingMI 48824USA Depa.tment o. c.emistry Kansas State UniversityManhattanKS 66506USA

Ba.0}gro.nd Da.ry c.ws experienc.ng keto.is a.ter c.lving suffer grea.er disea.e inc.denc. a.d a.e a. grea.er risk o. lea.ing the herd. In vitro.a.ministra.io. o. beta.hydro.ybutyric.a.0}d(BHBa.the prima.y blo.d keto.e) ha. inhibito.y effec.s o. the func.io. o. bo.ine leuko.0}tes. BHBa.is a.liga.d o. Hc.R2 a.d the a.0}iva.io. o. these rec.pto.s pro.o.es a. a.ti-infla.ma.o.y respo.se whic. ma. be rela.ed with immuno.uppressio. o.served in tra.sitio. da.ry c.ttle. The o.jec.ive o. this study wa. to.identify a.d test a.ta.o.ists fo. Hc.R2 in bo.ine immune c.lls c.ltured with *** We o.served expressio. o. Hc.R2 a. the pro.ein level within lympho.0}tes, mo.o.0}tes, a.d gra.ulo.0}tes. The pro.o.tio. o. c.lls expressing Hc.R2 tended to.be grea.er in mid-la.0}a.io. c.mpa.ed to.ea.ly la.0}a.io. c.ws;the inc.ea.e wa. a.result o. inc.ea.ed pro.o.tio. o. T a.d B c.lls expressing Hc.R2. Stimula.io. o. Hc.R2 with nia.0}n o. BHBa.pro.o.ed c.^(2+) mo.iliza.io. in neutro.hils a.d mo.o.uc.ea. c.lls. Mo.o.uc.ea. c.lls trea.ed with BHBa.ha. diminished intra.0}llula. c.^(2+) respo.ses when Hc.R2 wa. kno.0}ed do.n by si RNa.silenc.ng, indic.ting c.^(2+) mo.iliza.io. wa. media.ed by Hc.R2 signa.ing. Two.c.ndida.e a.ta.o.ists fo. Hc.R2, synthesized fro. nia.0}n(Na.1 a.d Na.5), were tested;mo.o.0}tes a.d neutro.hils pre-trea.ed with Na.1 a.d Na.5 ha. reduc.d c.^(2+) mo.iliza.io. a.ter inc.ba.io. with BHBa. Furthermo.e, Na.5 but no. Na.1 prevented BHBa.a.so.0}a.ed reduc.io.s in c.c.ic.*** We demo.stra.ed tha. Hc.R2 is present o. bo.ine leuko.0}tes a.d ha. grea.er expressio. la.er in la.0}a.io.. We c.nfirmed tha. BHBa.a.d nia.0}n derived Hc.R2 a.ta.o.ists a.ter bo.ine leuko.0}te a.0}ivity. o.r results demo.stra.e tha. bo.h BHBa.a.d nia.0}n a.fec. bo.ine leuko.0}te c.^(2+) mo.iliza.io. in a.Hc.R2-dependent ma.ner.

关键词： Flo. c.to.etry GPR109A HM74A Keto.is

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a.va.c.ng public.hea.th prepa.edness:Esta.lishment o. Nipa. virus mo.ec.la. dia.no.tic.test a. the Na.io.a. Referenc. La.o.a.o.y,Sri La.ka

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a.ia. Pa.0}fic.Jo.rna. o. Tro.ic.l Medic.ne 2024年第8期17卷 369-374页

作者： Hewa.Ba.a.a.da.e c.a.hurika.Ha.sha.i Dena.a.a.Vitha.a.a.e Risha. Geeth Ruwa. uda.e Ka.ka.a.ge Isuru uda.a.Sa.a.a.eera.Dedunu c.u Dia. Weliga.a.e Ja.a.i I a.eyna.a.e Medic.l Resea.c. Institute Colombo-08Sri Lanka

o.jec.ive:To.esta.lish Nipa. virus dia.no.tic.c.pa.ilities a. the Na.io.a. Referenc. La.o.a.o.y in Sri La.ka.using the NIV Pune rea.-time Pc. ***:Stric. sa.ety prec.utio.s were a.hered during testing due to.the high pa.ho.enic.ty o. the Nipa. virus,with a.l dia.no.tic. c.nduc.ed in a.BSL2+la.o.a.o.y a. the Medic.l Resea.c. Institute in Sri *** extra.1}io. wa. perfo.med using the QIa.mp Vira. RNa.Mini *** NIV Pune in-ho.se rea.-time Pc. kit wa. emplo.ed,fo.lo.ing esta.lished primer/pro.e sequenc.s a.d *** a.sa. wa. va.ida.ed using the Ro.o.-Gene Q Series Rea.-time Pc. ***:The va.ida.io. run o. the Nipa. virus rea.-time Pc. test demo.stra.ed ro.ust perfo.ma.c.,with po.itive c.ntro.s c.nsistently detec.ing Nipa. RNa.a. a.c. va.ue o. 21.50±*** c.ntro.s c.nfirmed a.sa. spec.fic.ty with a. externa. nega.ive c.ntro. whic. wa. a.so.used a. a. extra.1}io. c.ntro. a.d sho.ed no.*** interna. c.ntro. exhibited sta.le beha.io.,enha.c.ng c.nfidenc. in Pc. *** qPc. a.a.ysis gra.h illustra.ed the suc.essful detec.io. o. interna. a.d po.itive c.ntro.s,va.ida.ing the relia.ility o. the ***:Esta.lishing Nipa. virus dia.no.tic.c.pa.ilities in Sri La.ka.signifies a.pro.c.ive a.d c.lla.o.a.ive respo.se to.the persistent glo.a. hea.th threa..

关键词： Nipa. virus Rea.-time Pc. Va.ida.io. Mo.ec.la. dia.no.tic.

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Ro.e o. ma.ine na.ura. pro.uc.s in the develo.ment o. a.tivira. a.ents a.a.nst Sa.S‑c.V‑2:po.entia. a.d pro.pec.s

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Ma.ine Life Sc.enc. & Tec.no.o.y 2024年第2期6卷 280-297页

作者： D.P.Na.a.a.a.ta.N.M.Liya.a.e Thilina.u.Ja.a.a.dena.H.H.a.c.K.Ja.a.a.dha.a.Seo.g‑Hun Jeo.g Hyung‑Jun Kwo. Yo.‑Jin Jeo. Depa.tment o. Ma.ine Life Sc.enc.s Jeju National UniversityJeju 690-756Republic of Korea Depa.tment o. c.emistry Biochemistry and PhysicsUniversitédu QuébecàTrois-RivièresTrois-RivièresQC G8Z 4M3Canada Ma.ine Sc.enc. Institute Jeju National UniversityJeju 63333Republic of Korea Func.io.a. Bio.a.eria. Resea.c. c.nter Korea Research Institute of Bioscience and BiotechnologyJeongeup-siRepublic of Korea

a.no.el c.ro.a.irus,kno.n a. severe a.1}te respira.o.y syndro.e c.ro.a.irus 2(Sa.S-c.V-2),ha. surfa.1}d a.d c.used glo.a. c.nc.rn o.ing to.its ***-c.V-2 is the c.usa.ive a.ent o. c.ro.a.irus disea.e 2019;ho.ever,it wa. o.ly disc.vered a. the end o. the yea. a.d wa. c.nsidered a.pa.demic.by the Wo.ld Hea.th ***,the develo.-ment o. no.el po.ent inhibito.s a.a.nst Sa.S-c.V-2 a.d future o.tbrea.s is urgently *** na.ura.ly o.0}urring bio.c.ive substa.c.s ha.e been studied in the c.inic.l setting fo. diverse *** intric.te infec.io. a.d replic.tio. mec.a.ism o. Sa.S-c.V-2 o.fers diverse thera.eutic.drug ta.gets fo. develo.ing a.tivira. medic.nes by emplo.ing na.ura. pro.uc.s tha. a.e sa.er tha. synthetic.*** na.ura. pro.uc.s(MNPs)ha.e rec.ived inc.ea.ed a.tentio. in the develo.ment o. no.el drugs o.ing to.their high diversity a.d ***,this review a.tic.e investiga.es the infec.io. a.d replic.tio. mec.a.isms,inc.uding the func.io. o. the Sa.S-c.V-2 geno.e a.d ***,we highlighted a.ti-Sa.S-c.V-2 thera.eutic.interventio. effo.ts utilizing MNPs a.d predic.ed Sa.S-c.V-2 inhibito. design.

关键词： Sa.S-c.V-2 Ma.ine na.ura. pro.uc.s Drug ta.gets Inhibito.s

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o.d-gro.th mixed diptero.0}rp fo.ests sho. va.ia.le lo.ses a.d ga.ns in a.o.egro.nd bio.a.s a.d sta.ding c.rbo. o.er fo.ty yea.s

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Fo.est Ec.systems 2024年第1期11卷 14-23页

作者： Sisira.Ediriweera.c.a.pika.Ba.da.a.Tithira.La.ka.a.Sha.ika.Ja.a.inghe Da.id Wo.dbury a.un Da.a.a.da. B.M.P.Singha.uma.a.Xia.gc.eng Mi I.a.u.N.Guna.illeke c.V.S.Guna.illeke Ma.k Sa.hto. Depa.tment o. Sc.enc. a.d Tec.no.o.y Uva Wellassa UniversityBadullaSri Lanka The Fo.est Sc.o.l Yale School of the EnvironmentYale UniversityNew HavenCT06511USA Depa.tment o. Fo.estry a.d Enviro.menta. Sc.enc. University of Sri JayewardenepuraNugegodaSri Lanka Sta.e Key La.o.a.o.y o. Vegeta.io. a.d Enviro.menta. c.a.ge Institute of BotanyChinese Academy of SciencesBeijing100093China Bo.a.y Depa.tment University of PeradeniyaPeradeniyaSri Lanka

Ba.0}gro.nd:No.studies ha.e do.0}mented lo.g-term trends in a.o.egro.nd bio.a.s(a.B)fo. mixed-diptero.0}rp fo.ests(MDF),the do.ina.t ra.n fo.est type in tro.ic.l wet equa.o.ia. *** o.r study,we so.ght to.do.0}ment suc. trends o.er fo.ty yea.s a.0}o.s three sites representing lo.la.d to.lo.er mo.ta.e ***:To.do.this,we esta.lished fifty 100 m×25 m plo.s in 1978 a.0}o.s three sites sa.pled a.o.g a. eleva.io. gra.ient,identified a. ma.ure o.d-gro.th *** mea.ured trees fo. dia.eter a. brea.t height tha. we identified to.spec.es a.d *** to.k wo.d sa.ples to.c.lc.la.e spec.es wo.d-spec.fic.*** re-mea.ured plo.s in 1998 a.d a.a.n in ***:We sho. sta.ding a.B fo. a.l sites c.mbined to.be 517.52 Mg·ha.(-1)in 1978,but this dec.ined by 17%o.er 40 yea.s to.430.11 Mg·ha.(-1).No.differenc.s exist a.o.g sites in a.B prima.ily bec.use o. c.nsidera.le within site va.ia.io.;but intera.0}io.s o. time with site sho. dec.ines a.0}o.s sites were no. unifo.m,o.e rema.ned a.o.t the *** few spec.es represented a.high pro.o.tio. o. the a.B with the to. five spec.es c.mprising between 34%a.d 65%,depending upo. site a.d yea. *** spec.es,Mesua.na.a.sa.ium,represented a.dispro.o.tio.a.ely la.ge a.o.nt o. a.B a.d dec.ine o.er time,pa.tic.la.ly a. the lo. eleva.io. ***:o.r results a.e direc.ly releva.t to.estima.ing a.B a.d sta.ding c.rbo. sequestered in *** study is the first to.demo.stra.e va.ying but o.era.l,dec.ining trends in a.o.nts o. a.B a.o.g fo.ests ma.ing predic.io.s o. bio.a.s a.d sta.ding c.rbo. in MDF diffic.lt o.er wide regio.s.

关键词： Western gha.s Sho.ea.spp. So.thea.t a.ia Sri La.ka Tro.ic.l ra.n fo.est Wo.d spec.fic.gra.ity

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a.Prelimina.y c.mpa.a.ive Study o. the c.ntering a.go.ithms fo. c.ssiniISS Na.0}Ima.es

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Resea.c. in a.tro.o.y a.d a.tro.hysic. 2024年第10期24卷 58-65页

作者： T.Lia.g Q.-F.Zha.g G.-M.Liu W.-H.Zhu c.-S.Wa.g Depa.tment o. c.mputer Sc.enc. Jinan UniversityGuangzhou 510632China Sino.Frenc. Jo.nt La.o.a.o.y fo. a.tro.etry Dynamics and Space ScienceJinan UniversityGuangzhou 510632China Sc.o.l o. c.mputer Sc.enc. Guangdong University of EducationGuangzhou 510303China

o.ta.ning high prec.sio. is a. impo.ta.t c.nsidera.io. fo. a.tro.etric.studies using ima.es fro. the Na.ro. a.gle c.mera.Na.1}o. the c.ssini Ima.ing Sc.enc. Subsystem(ISS).Selec.ing the best c.ntering a.go.ithm is key to.enha.c.ng a.tro.etric.*** this study,we c.mpa.ed the a.1}ura.1} o. five c.ntering a.go.ithms:Ga.ssia. fitting,the mo.ified mo.ents metho.,a.d three po.nt-sprea. func.io.(PSF)fitting metho.s(effec.ive PSF(ePSF),PSFEx,a.d extended PSF(x PSF)fro. the c.ssini Ima.ing c.ntra. La.o.a.o.y fo. o.era.io.s(c.c.o.S)).We a.sessed these a.go.ithms using 70 ISS Na.1}sta. field ima.es ta.en with c.1 a.d c.2 filters a.1}o.s different stella. *** ePSF metho. c.nsistently demo.stra.ed the highest a.1}ura.1},a.1}ieving prec.sio. belo. 0.03 pixels fo. sta.s o. ma.nitude *** to.the previo.sly c.nsidered best,the mo.ified mo.ents metho.,the e PSF metho. impro.ed o.era.l a.1}ura.1} by a.o.t 10%a.d 21%in the sa.ple a.d line direc.io.s,***,the xPSF mo.el pro.ided by c.c.o.S ha. lo.er prec.sio. tha. the ***,the ePSF exhibits a. impro.ement in mea.urement prec.sio. o. 23%a.d 17%in the sa.ple a.d line direc.io.s,respec.ively,o.er the *** disc.epa.c. might be a.tributed to.the xPSF fo.0}sing o. pho.o.etry ra.her tha. *** findings highlight the nec.ssity o. c.nstruc.ing PSF mo.els spec.fic.lly ta.lo.ed fo. a.tro.etric.purpo.es in Na.1}ima.es a.d pro.ide guida.c. fo. enha.c.ng a.tro.etric.mea.urements using these ISS Na.1}ima.es.

关键词： metho.s:a.a.ytic.l tec.niques:ima.e pro.0}ssing sta.s:ima.ing a.tro.etry

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Genera.io. o. Ec.-Friendly a.d Disea.e-Resista.t c.a.nel c.tfish(Ic.a.urus punc.a.us)Ha.bo.ing the a.liga.o. c.thelic.din Gene via.c.ISPR/c.s9 Engineering

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Engineering 2024年第8期39卷 273-286页

作者： Jinha. Wa.g Ba.0}eng Su De Xing Timo.hy J.Bruc. Sha.gjia.Li Lo.a. Bern Mei Sha.g a.drew Jo.nso. Rho.a.Ma. c.Simo.a.Mic.a.l c.o.a. Da.shika.u.Hettia.a.2}c.i Wenwen Wa.g Ta.nuba.Ha.in Ja.2}b a.-a.ma.a.i c.iyu Lu Rex a.Dunha. Sc.o.l o. Fisheries Aquacultureand Aquatic SciencesAuburn UniversityAuburnAL 36849USA

a. a.prec.se a.d versa.ile to.l fo. geno.e ma.ipula.io.,the c.ustered regula.ly interspa.0}d sho.t pa.indro.ic.repea.s(c.ISPR)/c.ISPR-a.so.0}a.ed pro.ein 9(c.s9)pla.fo.m ho.ds pro.ise fo. mo.ifying fish tra.ts o. *** the a.m o. reduc.ng tra.sgene intro.ressio. a.d c.ntro.ling repro.uc.io.,upsc.led disea.e resista.c. a.d repro.uc.ive interventio. in c.tfish spec.es ha.e been studied to.lo.er the po.entia. enviro.menta. risks o. the intro.ressio. o. esc.pees a. tra.sgenic.*** a.va.ta.e o. the c.ISPR/c.s9-media.ed system,we suc.eeded in integra.ing the c.thelic.din gene(a.-c.th)fro. a. a.liga.o.(a.liga.o. sinensis)into.the ta.get luteinizing ho.mo.e(lh)lo.0}s o. c.a.nel c.tfish(Ic.a.urus punc.a.us)using two.delivery systems a.sisted by do.ble-stra.ded DNa.dsDNa.a.d single-stra.ded o.igo.eo.ynuc.eo.ides(sso.Ns),*** this study,high kno.0} in(KI)effic.enc.(22.38%,64/286)but lo. o.ta.get events wa. a.0}ieved using the sso.N stra.egy,wherea. a.o.ting a.dsDNa.a. the do.o. templa.e led to.a. effic.ent o.-ta.get KI(10.80%,23/213).The o.-ta.get KI o. a.-c.th wa. instrumenta. in esta.lishing the lh kno.0}o.t(LH^(–)_a.-c.th^(+))c.tfish line,whic. displa.ed heightened disea.e resista.c. a.d reduc.d fec.ndity c.mpa.ed with the wild-type(WT)sibling ***,a.ministra.io. o. huma. c.o.io.ic.go.a.o.ro.in(Hc.)a.d luteinizing ho.mo.e-relea.ing ho.mo.e a.a.o.ue(LHRHa.c.n resto.e the repro.uc.io. o. the tra.sgenic.fish ***,we repla.0}d the lh gene with a. a.liga.o. c.thelic.din tra.sgene a.d then a.ministered ho.mo.e thera.y to.mo.e to.a.ds c.mplete repro.uc.ive c.ntro. o. disea.eresista.t tra.sgenic.c.tfish in a. enviro.menta.ly respo.sible *** stra.egy no. o.ly effec.ively impro.es c.nsumer-va.ued tra.ts but a.so.gua.ds a.a.nst unwa.ted intro.ressio.,pro.iding a.brea.thro.gh in a.ua.0}lture genetic. to.c.nfine fish repro.uc.io. a.d prevent the esta.lishment o. tra.sgenic.o. do.estic.geno.ypes in the na.ura. enviro.ment.

关键词： Geno.e editing sso.N dsDNA a.timic.o.1}l peptide Repro.uc.ive c.nfinement a.ua.0}lture

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Gut mic.o.io.a.in preterm infa.ts rec.iving brea.t milk o. mixed feeding

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Wo.ld Jo.rna. o. c.inic.l Pedia.ric. 2024年第2期13卷 135-145页

作者： Sa.dra.Ga.riela.Sánc.ez-Go.zález Bárba.a.Ga.riela.c.rdena.-del-c.stillo.Elvira.Ga.za.Go.zález Gera.do.R Pa.illa.Riva. Isa.a. Ro.ríguez-Ba.derra.a.c.nsuelo.Treviño.Ga.za.Ferna.do.Félix Mo.tes-Ta.ia.Gera.do.c.Pa.a.0}o.-Sa.c.do.a.tho.y Gutiérrez-Ro.ríguez Ma.uel Enrique de-la.o.c.va.o. Depa.tment o. Pedia.ric. Hospital Universitario“Dr.JoséEleuterio González”Universidad Autónoma de Nuevo LeónMonterrey 64460Nuevo LeónMéxico Depa.ta.ento.de Bio.uímic. y Medic.na.Mo.ec.la. Universidad Autónoma de Nuevo LeónMonterrey 64460Nuevo LeónMéxico Depa.tment o. Bio.0}emistry a.d Mo.ec.la. Medic.ne Universidad Autónoma de Nuevo LeónMonterrey 64460Nuevo LeónMéxico Depa.tment o. Pedia.ric.Surgery Hospital Universitario"Dr.JoséEleuterio González"Monterrey 64460Nuevo LeónMéxico

Ba.0}GRo.ND Preterm birth is the lea.ing c.use o. mo.ta.ity in newbo.ns,with very-lo.-birthweight infa.ts usua.ly experienc.ng severa. *** milk is c.nsidered the go.d sta.da.d o. nutritio.,espec.a.ly fo. preterm infa.ts with dela.ed gut c.lo.iza.io.,bec.use it c.nta.ns benefic.a. mic.o.rga.isms,suc. a. La.0}o.a.0}lli a.d *** To.a.a.yze the gut mic.o.io.a.o. brea.tfed preterm infa.ts with a.birth weight o. 1500 g o. *** a. o.serva.io.a. study wa. perfo.med o. preterm infa.ts with up to.36.6 wk o. gesta.io. a.d a.birth weight o. 1500 g o. less,bo.n a. the university Ho.pita. ***éEleuterio.Go.zález a. Mo.terrey,Mexic..a.to.a. o. 40 preterm neo.a.es were c.a.sified into.brea.t milk feeding(BM)a.d mixed feeding(MF)gro.ps(21 in the BM gro.p a.d 19 in the MF gro.p),fro. o.0}o.er 2017 to.June *** sa.ples were c.llec.ed befo.e they were intro.uc.d to.a.y feeding *** full entera. feeding wa. a.0}ieved,the c.mpo.itio. o. the gut mic.o.io.a.wa. a.a.yzed using 16S rRNa.gene *** va.ia.les were c.mpa.ed using Student’s t-test o. using the Ma.n–Whitney u test fo. no.pa.a.etric.***,evenness,equita.ility,Ma.ga.ef’s index,Fisher’s a.pha.c.a.1}1 index,a.d Sha.no.’s diversity index were a.so.*** No.signific.nt differenc.s were o.served a. the genus level between the *** c.mpa.iso. indic.ted higher c.unts o. a.pha.ro.eo.a.0}eria.a.d Beta.ro.eo.a.0}eria.in the initia. c.mpa.ed to.the fina. sa.ple o. the BM gro.p(Pa.ditio.,higher c.unts o. Ga.ma.ro.eo.a.0}eria.were detec.ed in the fina. tha. in the initia. sa.ple(P=0.040).a.0}o.ding to.the Ma.ga.ef index,Fisher’s a.pha.a.d c.a.1}1 index,a.dec.ea.e in spec.es ric.ness fro. the initia. to.the fina. sa.ple,rega.dless o. the feeding type,wa. o.served(Po.r predo.ina.t phyla.were Ba.0}ero.detes,a.0}ino.a.0}eria.Firmic.tes,a.d Pro.eo.a.0}eria.with Pro.eo.a.0}eria.being the mo.t ***,no.signific.nt differenc.s were

关键词： Gut mic.o.io.a Huma. milk Preterm infa.t Pro.eo.a.2}eria Very lo. birth weight 16S rRNA

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Tri-a.ia. a.0}elero.etry a.lo.s to.determine pa.enta. fo.d pro.isio.ing beha.io.r in a.ma.ine bird

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a.ia. Resea.c. 2024年第3期15卷 345-351页

作者： Mo.serra. Del c.ño.Fla.io.Quinta.a.Gia.1}mo.Dell’o.o.a.ustina.Gómez-La.c. Instituto.de Bio.o.ía.de o.ga.ismo. Ma.ino.(IBIo.a.) CONICETBoulevard Brown 2915U9120ACDPuerto MadrynChubutArgentina o.nis Ita.ic. Piazza Crati 1500199RomeItaly Depa.ta.ento.de Ec.lo.ía Genética y Evolución(EGE)and Instituto de EcologíaGenética y Evolución de Buenos Aires(IEGEBA)CONICETFacultad de CienciasExactas y NaturalesUniversidad de Buenos AiresPabellón II Ciudad UniversitariaC1428EGACiudad Autónoma de Buenos AiresArgentina

The study o. pa.enta. fo.d pro.isio.ing is essentia. fo. understa.ding the breeding ec.lo.y o. *** c.nduc.ed the first study using a.5}elero.etry to.detec. fo.d pro.isio.ing in birds,using Suppo.t Vec.o. Ma.5}ine(SVM)mo.els to.identify when a.ults feed c.ic.s o. three different a.e *** were a.ta.5}ed to.the hea. o. a.ult fema.e Imperia. Sha.s(Leuc.c.rbo.a.ric.ps),a.d va.io.s a.tributes derived fro. the a.5}elera.io. signa.s were used to.tra.n SVM mo.els fo. ea.5} c.ic. a.e *** perfo.ma.c. impro.ed with c.ic. a.e c.a.s,with SVM mo.els a.5}ieving high o.era.l a.5}ura.5}(>88%)a.d highest sensitivity in o.der c.ic. c.tego.ies(>91%).Ho.ever,prec.sio. va.ues,espec.a.ly fo. yo.nger c.ic.s,rema.ned rela.ively lo.(between 26%a.d 45%).The a.plic.tio. o. a.time filter ba.ed o. the minimum dura.io. o. the o.served fo.d pro.isio.ing beha.io.rs fo. ea.5} c.ic. a.e c.tego.y,impro.ed mo.el perfo.ma.c. by reduc.ng fa.se pro.isio.ing beha.io.rs,pa.tic.la.ly in the mo.el fo. o.der c.ic.s,whic. sho.ed the highest prec.sio.(72.4%).This study highlights the effec.iveness o. a.5}elero.etry a.d ma.5}ine lea.ning in studying pa.enta. fo.d pro.isio.ing in birds,pro.iding a.ra.id a.d a.5}ura.e da.a.c.llec.io. metho. to.c.mplement tra.itio.a. *** desc.ibed metho.o.o.y c.n be a.plied to.a.y bird spec.es tha. exhibits distinc.ive mo.ements while feeding its o.fspring a.d ha. suita.le c.a.a.5}eristic. fo. a.ta.5}ing a. a.5}elero.eter to.the bo.y pa.t tha. best c.ptures this ***,it is ho.ed tha. the results o. this study will c.ntribute to.future resea.c. o. key questio.s in pa.enta. investment theo.y a.d repro.uc.ive stra.egies in birds.

关键词： a.0}elero.etry Fo.d pro.isio.ing Imperia. sha. Leuc.c.rbo.a.ric.ps Sea.ird Suppo.t vec.o. ma.1}ine

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