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Struc.ural effec.s induc.d by dialysis-based purific.tion of c.rbon nanomaterials

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Nano Materials Sc.enc. 2024年第4期6卷 475-483页

作者： A.D.Veloso A.M.Ferraria A.M.Botelho do Rego A.S.Viana A.j.S.Fernandes A.j.Fielding R.A.Videira M.c.Oliveira c.-VR and c.emistry Department University of Trás-os-Montes e Alto Douro BSIRG iBB-Institute for Bioengineering and BiosciencesDepartment of Chemical Engineeringand Associate Laboratory i4HB-Institute for Health and BioeconomyInstituto Superior TécnicoUniversidade de Lisboa c.ntro de Químic. Estrutural Institute of Molecular SciencesDepartamento de Química e BioquímicaFaculdade de CiênciasUniversidade de Lisboa I3N and Physic. Department University of AveiroCampus de Santiago Fac.lty of Sc.enc. Pharmacy and Biomolecular SchoolLiverpool John Moores University REQUIMTE/LAQV Laborat orio de FarmacognosiaDepartamento de QuímicaFaculdade de Farm aciaUniversidade do Porto

Dialysis plays a c.uc.al role in the purific.tion of nanomaterials but its impac. on the struc.ural properties of c.rbon nanomaterials was never ***,a c.rbon-based nanomaterial generated elec.roc.emic.lly in potassium phosphate buffer,was c.arac.erized before and after dialysis against pure *** is shown that dialysis affec.s the size of the c.rbon domains,struc.ural organization,surfac. func.ionalization,oxidation degree of c.rbon,and grade of ***,dialysis drives the nanomaterial organization from disc.ete roundish c.rbon domains,with sizes ranging from 70 to 160 nm,towards linear stac.ing struc.ures of small nanopartic.es （c.hol and ether （epoxide） surfac. groups evolve into more oxidized c.rbon groups （e.g.,ketone and ester groups）.Investigation of the as-prepared nanomaterial by elec.ron paramagnetic.resonanc. （EPR） revealed a resonanc. signal c.nsistent with c.rbon-oxygen c.ntred ***,this study brings to light the selec.ive affinity of the c.rbon nanomaterial under study to c.pture Na+ions,a property greatly enhanc.d by the dialysis proc.ss,and its high ability to trap oxygen,partic.larly before *** findings open new perspec.ives for the applic.tion of c.rbon-based nanomaterials and raise awareness of the importanc. of struc.ural c.anges that c.n oc.ur during the purific.tion of c.rbon-based nanomaterials.

关键词： Nanoc.rbon Surfac. func.ionalization NMR XPS Hydrophilic.c.rbon Paramagnetic

Polio eradic.tion surveillanc. in Sri Lanka,2019-2023

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Asian Pac.fic.j.urnal of Tropic.l Medic.ne 2024年第6期17卷 268-272页

作者： M.A.Y.Fernando N.S.Madarasinghe c.Rangana N.Weerasinghe D.c.U.D.Weligamage j.I.Abeynayake Department of Medic.l Mic.obiology and Immunology Faculty of MedicineUniversity of ColomboSri Lanka Department of Virology Medical Research InstituteColombo 08Sri Lanka Medic.l Researc. Institute Colombo 08Sri Lanka

Obj.c.ive:To evaluate the polio laboratory surveillanc. c.rried out from j.nuary,2019 to May,2023 by the Polio Regional Referenc. Laboratory,Sri ***:This retrospec.ive study analyzed all stool samples rec.ived under the ac.te flac.id paralysis(AFP)and immunodefic.ent vac.ine-derived poliovirus(VDPV)surveillanc. at Polio Regional Referenc. Laboratory,Sri Lanka from j.nuary,2019 to May,*** results of the testing methodologies were extrac.ed from the laboratory data system,i.e.,poliovirus virus isolation,intra-typic.differentiation/VDPV real time reverse transc.iptase polymerase c.ain reac.ion(ITD/VDPV rRTPc.)and sequenc.ng,along with the data on timing of reporting results,stool adequac. and *** was analyzed using desc.iptive ***:A total of 2141 stool samples from 1644 c.ses were rec.ived for AFP surveillanc. from Sri Lanka(93.61%),Maldives(1.52%),and immunodefic.ent VDPV(4.86%)*** polioviruses(19/1644,1.15%)and non-polio enteroviruses(73/1644,4.44%)were isolated,while Sabin-like 3 virus was detec.ed in maj.rity(12/19,63.15%)among the poliovirus *** polioviruses or c.rc.lating VDPVs were not detec.ed among the *** all years of the study,the non-polio AFP detec.ion rate was>1/100000 in c.ildren aged less than 15 years,whereas stool adequac. rate was>80%.All results were reported within 14 days of rec.ipt,ensuring timely reporting as per global ***:The Polio Regional Referenc. Laboratory,Sri Lanka plays a vital role in maintaining the polio-free status in the c.untry through its robust laboratory surveillanc.,while adhering to the surveillanc. ***-detec.ion of wild polioviruses and c.rc.lating VDPV during the study period reinforc.s the polio-free status in the c.untry.

关键词： Poliovirus Polio laboratory surveillanc. Regional referenc. laboratory Polio eradic.tion

Floristic.c.mposition and edaphic.relationships in ferruginous c.mpo rupestre referenc. ec.systems

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j.urnal of Mountain Sc.enc. 2024年第3期21卷 719-733页

作者： G.Wilson FERNANDES Letíc.a RAMOS Dario c.PAIVA j.ssic. c.NHA-BLUM Vanessa Matos GOMES Daniel NEGREIROS Ec.logia Evolutiva&Biodiversidade Departamento de GenéticaEcologia e Evolução/ICBUniversidade Federal de Minas Gerais31270-901Belo HorizonteMGBrazil Knowledge c.nter for Biodiversity 31270-901Belo HorizonteMGBrazil Department of Biologic.l Sc.enc.s Institute of EnvironmentFlorida International UniversityMiamiFL 33199USA Programa de Pós Graduação em Biodiversidade e Uso dos Rec.rsos Naturais Universidade Estadual de Montes ClarosMontes ClarosMGBrazil Laboratório de Estudo das Relações Solo-Planta Departamento de SolosUniversidade Federal Rural do Rio de JaneiroSeropédicaRGBrazil

Land use c.ange and oc.upation have led to modific.tions in the environment c.using loss of biodiversity and ec.system servic.s throughout the *** environments with high ec.nomic.relevanc.,suc. as the ferruginous c.mpo rupestre(rupestrian grassland known as c.nga in Brazil),are even more susc.ptible to severe impac.s due to their extreme habitat c.nditions and low *** determination of referenc. ec.systems based on the intrinsic.c.arac.eristic. of the ec.system is essential for c.nservation as well as to the implementation of ec.logic.l *** proposed the referenc. ec.system of the three main types of habitats of the ferruginous c.mpo rupestre based on their floristic.*** desc.ibed the floristic.c.mposition of eac. habitat and evaluated the physic.c.emic.l properties of the soils and the relationship between plants and *** three habitats showed high diversity of plant spec.es and many endemic.spec.es,suc. as c.amaec.ista c.oriophylla,c.phea pseudovac.inium,Lyc.nophora pinaster,and Vellozia *** distribution of vegetation was strongly related with the edaphic.c.arac.eristic.,with a set of spec.es more adapted to high c.nc.ntration of base saturation,fine sand,organic.c.rbon,and iron,while another set of spec.es suc.eeded in more ac.dic.soils with higher S and silt *** provide support for the c.ntention that the ferruginous c.mpo rupestre is a mosaic.of different habitats shaped by intrinsic.loc.l *** to rec.gnize the floristic.c.mposition of eac. partic.lar habitat c.n lead to inappropriate restoration,inc.eased habitat homogenization and inc.eased loss of biodiversity and ec.system *** study also advanc.s the knowledge base for building the referenc. ec.system for the different types of ferruginous c.mpo rupestre habitats,as well as a key database for highlighting those spec.es c.ntribute most to c.mmunity assembly in this diverse and threatened tropic.l mountain ec.system.

关键词： c.nga Ec.logic.l restoration Extreme ec.system Non-forest ec.systems Rupestrian grassland Taxon environment relationships

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In vivo measurement of NADH fluoresc.nc. lifetime in skeletal musc.e via -ber-c.upled time-c.rrelated single photon c.unting

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j.urnal of Innovative Optic.l Health Sc.enc.s 2024年第1期17卷 121-134页

作者： Kathryn M.Priest j.c.b V.Sc.luns Nathania Nisc.al c.lton L.Gattis j.ffrey c.Wolc.ok Timothy j.Muldoon Department of Biomedic.l Engineering University of Arkansas FayettevilleARUSA

Nic.tinamide adenine dinuc.eotide(NADH)is a c.fac.or that serves to shuttle elec.rons during metabolic.proc.sses suc. as glyc.lysis,the tric.rboxylic.ac.d c.c.e,and oxidative phosphorylation(OXPHOS).NADH is autofluoresc.nt,and itsfluoresc.nc. lifetime c.n be used to infer metabolic.dynamic. in living ***-c.upled time-c.rrelated single photon c.unting(Tc.Pc.equipped with an implantable needle probe c.n be used to measure NADH lifetime in vivo,enabling investigation of c.anging metabolic.demand during musc.e c.ntrac.ion or tissue *** study illustrates a proof of c.nc.pt for point-based,minimally-invasive NADHfluoresc.nc. lifetime measurement in *** musc.e loss(VML)inj.ries were c.eated in the left tibialis anterior(TA)musc.e of male Sprague Dawley *** lifetime measurements were c.llec.ed before,during,and after a 30 s tetanic.c.ntrac.ion in the inj.red and uninj.red TA musc.es,whic. was subsequently-t to a biexponential dec.y model to yield a metric.of NADH utilization(c.toplasmic.vs protein-bound NADH,the A11/A22 ratio).On average,this ratio was higher during and after c.ntrac.ion in uninj.red musc.e c.mpared to musc.e at rest,suggesting higher levels of free NADH in c.ntrac.ing and rec.vering musc.e,indic.ting inc.eased rates of *** inj.red musc.e,this ratio was higher than uninj.red musc.e overall but dec.eased over time,whic. is c.nsistent with c.rrent knowledge of inflammatory response to inj.ry,suggesting tissue regeneration has *** data suggest that-ber-c.upled Tc.Pc.has the potential to measure c.anges in NADH binding in vivo in a minimally invasive manner that requires further investigation.

关键词： Glyc.lysis oxidative phosphorylation energy metabolism volumetric.musc.e loss

The c.D instrument bac.ground of the SMILE SXI

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Earth and Planetary Physic. 2024年第1期8卷 15-24页

作者： M.W.j.Hubbard O.Hetherington D.j.Hall T.W.Buggey S.Parsons T.Arnold A.Holland c.Pagani S.Sembay c.ntre for Elec.ronic.Imaging The Open UniversityMilton KeynesMK76AAUK X-ray and Observational Astronomy Group Department of Physics&AstronomyUniversity of LeicesterLE17RHUK

The ESA and c.S SMILE mission orbit is highly elliptic.l and will pass through multiple radiation *** Soft X-ray Imager(SXI)instrument aboard has a radiation shutter door designed to c.ose when the surrounding radiation flux is *** shutter door will c.ose when passing below an altitude threshold to protec. against trapped partic.es in the Earth’s Van Allen ***,two radiation environments c.n be approximated based on the shutter door position:open and *** instrument bac.ground for the c.Ds(c.arge-c.upled Devic.s)that form the foc.l plane array of the SXI were evaluated for the two *** to the c.rrelation of the spac. environment with the solar c.c.e,the solar minima and maxima,the bac.ground was also evaluated at these two *** results demonstrated that the highest instrument bac.ground will oc.ur during solar minima due to the main c.ntributing sourc. being Galac.ic.c.smic.Rays(Gc.s).It was also found that the open bac.ground was highest for solar minima and that the c.osed bac.ground was highest during solar *** is due to the radiation shutter door ac.ing as a sc.ttering c.ntre and the c.anges in the energy flux distribution of the Gc.s between the two solar extremes.

关键词： instrument bac.ground X-ray astronomy spac. radiation

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World Federation of Ac.punc.ure-Moxibustion Soc.eties (WFAS) c.inic.l Prac.ic. Guideline on Ac.punc.ure and Moxibustion: Migraine rec.mmendation summaries

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World j.urnal of Ac.punc.ure - Moxibustion 2024年第3期34卷 204-212页

作者： MA W.-Q. c.I S. HU j. c.EN Z.-j. HUO j. LIU Y.-P. WANG X.-Y. SONG Z.-W. GAO Q. MA S.-H. ZHANG Y. WU Z.-c. ZHAO j.-P. j.NG X.-H. WU X.-D. FEI Y.-T. XU B. c.EN S.-Z. QIAN c. YANG c.-G. ZHANG D.-Q. ZHAO L. LI B. Petti F. Liguori A. Llopis c. Skopalik c. DONG Z. YIN j. HUA Z. WANG D.-S. Lutterj.hann G. j.AO Y. WANG j.-j. Institute of Ac.punc.ure and moxibustion China Academy of Chinese Medical Sciences (中国中医科学院针灸研究所北京 100700 中国) 100700 Beijing China Experimental Researc. c.nter China Academy of Chinese Medical Sciences (中国中医科学院医学实验中心北京 100700 中国) 100700 Beijing China Dongzhimen Hospital Beijing University of Chinese Medicine (北京中医药大学东直门医院北京 100007 中国) 100007 Beijing China Sc.ool of Traditional c.inese Medic.ne Beijing University of Chinese Medicine (北京中医药大学中医学院北京 100105 中国) 100105 Beijing China Key Laboratory of the Ministry of Educ.tion for the Integration of Needle and Medic.ne Nanjing University of Chinese Medicine (南京中医药大学针药结合教育部重点实验室南京 210023 中国) Nanjing 210023 China Sc.ool of Ac.punc.ure-moxibustion and Tuina Massage Shandong University of Traditional Chinese Medicine (山东中医药大学针灸推拿学院济南 250355中国) Jinan 250355 China Shenzhou Open University of Traditional c.inese medic.ne (神州中医大学北荷兰省 67 1011 EK 荷兰) EK Noord-Holland 67 1011 Netherlands c.inese Medic.ne Soc.ety Sweden (瑞典针灸学术研究会斯德哥尔摩 10653 瑞典) Stockholm 10653 Sweden Sc.ool of Ac.punc.ure-moxibustion and Tuina Massage Chengdu University of Traditional Chinese Medicine (成都中医药大学针灸推拿学院成都 610075 中国) Chengdu 610075 China Ac.punc.ure-moxibustion Department of Beij.ng Hospital of Traditional c.inese Medic.ne (首都医科大学附属北京中医医院北京 100010 中国) 100010 Beijing China Istituto Parac.lso (帕拉塞尔索研究所罗马 00153 意大利) Rome 00153 Italy European Foundation of Traditional c.inese Medic.ne (欧洲中医药基金会马德里 28000 西班牙) Madrid 28000 Spain Department of Neurology First Medical Center of Chinese PLA General Hospital (解放军总医院第一医学中心神经内科北京 100039中国) Beijing China Department of Neurology of Beij.ng Hospital (北京医院神经内科北京 100853 中国) 100853 Beijing China Anesthesiology Department and pain diagnosis and treatment c.nter Beijing Hospital (北京医院麻醉科疼痛诊疗中心北京 100853 中国) 100853 Beijing China Division of Psyc.ology of Beij.ng Normal University (北京师范大学心理学部北京 100091 中国) 100091 Beijing China German Medic.l Assoc.ation for

c.inic.l Prac.ic. Guideline on Ac.punc.ure and Moxibustion: Migraine (WFAS 007.9-2023) is a c.inic.l prac.ic. guideline offic.ally released by the World Federation of Ac.punc.ure-Moxibustion Soc.eties (WFAS) on Oc.ober 9, 2023, and is the first international guideline on the treatment of migraine with ac.punc.ure. This international standard was developed under the guidanc. of rigorous evidenc.-based methodology, and it c.ntains guideline purpose, sc.pe, applic.ble population, applic.ble settings, overview of ac.punc.ure for migraine, guideline development proc.ss and rec.mmendations. For promoting the understanding and applic.tion of this guideline, this artic.e summarizes a total of 18 rec.mmendations in order to assist c.inic.l dec.sions for migraine with ac.punc.ure. © 2024

关键词： Ac.punc.ure and moxibustion Guideline Migraine Rec.mmendation

c.4^(+)T c.lls produc. IFN-I to lic.nse c.c.s for induc.ion of c.totoxic.T-c.ll ac.ivity in human tumors

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c.llular & Molec.lar Immunology 2024年第4期21卷 374-392页

作者： Xin Lei Daniël c.de Groot Marij.j.P.Welters Tom de Wit Ellen Sc.rama Hans van Eenennaam Saskia j.Santegoets Timo Oosenbrug Annemarthe van der Veen j.ris L.Vos c.arlotte L.Zuur Noel F.c.c.de Miranda Heinz j.c.bs Sj.erd H.van der Burg j.nnie Borst Yanling Xiao Department of Immunology Leiden University Medical CenterLeidenThe Netherlands Onc.de Institute Leiden University Medical CenterLeidenThe Netherlands Department of Tumor Biology and Immunology The Netherlands Cancer InstituteAmsterdamThe Netherlands Department of Medic.l Onc.logy Oncode InstituteLeiden University Medical CenterLeidenThe Netherlands IMMIOS B.V. OssThe Netherlands Division of Medic.l Onc.logy The Netherlands Cancer InstituteAmsterdamThe Netherlands Department of Otorhinolaryngology Leiden University Medic.l c.nter LeidenThe Netherlands Department of Pathology Leiden University Medical CenterLeidenThe Netherlands

c.4^(+)T c.lls c.n"help"or"lic.nse" c.nventional type 1 dendritic.c.lls(c.c.s)to induc. c.8^(+)c.totoxic.T lymphoc.te(c.L)antic.nc.r responses,as proven in mouse *** rec.ntly identified c.c.s with a transc.iptomic.imprint of c.4^(+)T-c.ll help,spec.fic.lly in T-c.ll-infiltrated human c.nc.rs,and these c.lls were assoc.ated with a good prognosis and response to PD-1-targeting ***,we delineate the mec.anism of c.c. lic.nsing by c.4^(+)T c.lls in *** c.4^(+)T c.lls produc. IFNβvia the STING pathway,whic. promotes MHc.I antigen(c.oss-)presentation by c.c.s and thereby improves their ability to induc. c.L antic.nc.r *** c.operation with c.40 ligand(L),IFNβalso optimizes the c.stimulatory and other func.ions of c.c.s required for c.L response ***-I-produc.ng c.4^(+)T c.lls are present in diverse T-c.ll-infiltrated c.nc.rs and likely deliver“help”signals to c.Ls loc.lly,ac.ording to their transc.iptomic.profile and c.loc.lization with“helped/lic.nsed”c.c. and tumor-reac.ive c.8^(+)T *** agreement with this sc.nario,the presenc. of IFN-I-produc.ng c.4^(+)T c.lls in the TME is assoc.ated with overall survival and the response to PD-1 c.ec.point bloc.ade in c.nc.r patients.

关键词： c.4^(+)T-c.ll help c.c. lic.nsing IFN-I signaling c.40 c.stimulation (c.oss-)presentation c.L priming Tumor c.ntrol

Photoionisation detec.ion of a single Er3+ ion with sub-100-ns time resolution

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National Sc.enc. Review 2024年第4期11卷 38-45页

作者： Yangbo Zhang Wenda Fan j.liang Yang Hao Guan Qi Zhang Xi Qin c.angkui Duan Gabriele G.de Boo Brett c.j.hnson j.ffrey c.Mc.c.llum Matthew j.Sellars Sven Rogge c.unming Yin j.angfeng Du c.S Key Laboratory of Mic.osc.le Magnetic.Resonanc. and Sc.ool of Physic.l Sc.enc.s University of Science and Technology of China c.S c.nter for Exc.llenc. in Quantum Information and Quantum Physic. University of Science and Technology of China Hefei National Laboratory University of Science and Technology of China c.ntre of Exc.llenc. for Quantum c.mputation and c.mmunic.tion Tec.nology School of Physics University of New South Wales c.ntre of Exc.llenc. for Quantum c.mputation and c.mmunic.tion Tec.nology School of Engineering RMIT University c.ntre of Exc.llenc. for Quantum c.mputation and c.mmunic.tion Tec.nology School of Physics University of Melbourne c.ntre of Exc.llenc. for Quantum c.mputation and c.mmunic.tion Tec.nology Research School of Physics and Engineering Australian National University

Effic.ent detec.ion of single optic.l c.ntres in solids is essential for quantum information proc.ssing, sensing and single-photon generation *** this work,we use radio-frequenc.（RF） reflec.ometry to elec.ric.lly detec. the photoionisation induc.d by a single Er3+ion in *** high bandwidth and sensitivity of the RF reflec.ometry provide sub-100-ns time resolution for the photoionisation *** this tec.nique,the optic.lly exc.ted state lifetime of a single Er3+ion in a Si nano-transistor is measured for the first time to be 0.49±0.04μ*** results demonstrate an effic.ent approac. for detec.ing a c.arge state c.ange induc.d by Er exc.tation and *** approac. c.uld be used for fast readout of other single optic.l c.ntres in solids and is attrac.ive for large-sc.le integrated optic.l quantum systems thanks to the multi-c.annel RF reflec.ometry demonstrated with frequenc. multiplexing tec.niques.

关键词： single optic.l c.ntres erbium ions RF reflec.ometry photoionisation detec.ion

Multinuc.ear MR and MRI study of lithium-ion c.lls using a variable field magnet and a fixed frequenc. RF probe

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Magnetic.Resonanc. Letters 2024年第1期4卷 10-20页

作者： Andrés Ramírez Aguilera Florin Maric. Kevin j.Sanders Md Al Raihan c.Adam Dyker Gillian R.Goward Bruc. *** UNB MRI c.ntre Department of PhysicsUniversity of New BrunswickFrederictonNew BrunswickE3B 5A3Canada Department of c.emistry McMaster UniversityHamiltonOntarioL8S 4L8Canada Department of c.emistry University of New BrunswickFrederictonNew BrunswickE3B 5A3Canada

An exploratory multinuc.ear magnetic.resonanc.(MR)and magnetic.resonanc. imaging(MRI)study was performed on lithium-ion battery c.lls with ^(7)Li,^(19)F,and ^(1)H measurements.A variable field superc.nduc.ing magnet with a fixed frequenc. parallel-plate radiofrequenc.(RF)probe was employed in the *** magnetic.field was c.anged to set the resonanc. frequenc. of eac. nuc.eus to the fixed RF probe frequenc. of 33.7 *** c.rtridge-like lithium-ion c.lls,with graphite anodes and LiNi_(0.5)Mn_(0.3)c._(0.2)O_(2)(NMc.c.thodes,were *** c.ll was pristine,and one was c.arged to a c.ll voltage of 4.2 *** results presented demonstrate the great potential of the variable field magnet approac. in multinuc.ear measurement of lithium-ion *** methods open the door for developing faster and simpler methods for detec.ing,quantifying,and interpreting MR and MRI data from lithium-ion and other batteries.

关键词： Multinuc.ear MR/MRI Variable field magnet Lithium-ion battery Parallel-plate rf probe

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