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chemerin, a novel player in inflammatory bowel disease

cellular & Molecular Immunology 2014年第4期11卷 315-316页

作者： c buechler Department of Internal Medicine I Regensburg University Hospital Regensburg Germany

Inflammatory bowel disease （IBD） manifests during crohn＇s disease and ulcerative colitis as well as in a group of inflammatory disorders of the gastrointestinal tract.1 The etiology of IBD is thought to be a combin... 详细信息

关键词： crohn病结肠炎溃疡性免疫系统双RNA病毒科感染宏基因组胃肠道血气分析胰岛素

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Adiponectin,a key adipokine in obesity related liver diseases

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World Journal of Gastroenterology 2011年第23期17卷 2801-2811页

作者： christa buechler Josef Wanninger Markus Neumeier Department of Internal Medicine I University Hospital of RegensburgD-93042 RegensburgGermany

Non-alcoholic fatty liver disease (NAFLD) comprising hepatic steatosis,non-alcoholic steatohepatitis (NASH),and progressive liver fibrosis is considered the most common liver disease in western *** liver is more prevalent in overweight than normal-weight people and liver fat positively correlates with hepatic insulin *** steatosis is regarded as a benign stage of NAFLD but may progress to NASH in a subgroup of *** liver biopsy no diagnostic tools to identify patients with NASH are available,and no effective treatment has been *** obesity is a main risk factor for NAFLD and inappropriate storage of triglycerides in adipocytes and higher concentrations of free fatty acids may add to increased hepatic lipid storage,insulin resistance,and progressive liver *** of the adipose tissue-derived proteins are elevated in obesity and may contribute to systemic inflammation and liver *** is highly abundant in human serum but its levels are reduced in obesity and are even lower in patients with hepatic steatosis or *** antagonizes excess lipid storage in the liver and protects from inflammation and *** review aims to give a short survey on NAFLD and the hepatoprotective effects of adiponectin.

关键词： Hepatic steatosis Non-alcoholic steatohepatitis Adiponectin Obesity Adipose tissue

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EurBeST——商业养蜂条件下的抗螨蜂种选育

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中国蜂业 2024年第2期75卷 22-23页

作者： R.buechler A.Uzunov c.costa M.Meixner Y Le conte F.Mondet M.Kovacic S.Andonov N.L.carreck L.Dimitrov B.Basso M.Bienkowska R.Dall’Olio F.Hatjina U.Wirtz 陈超(文\图) 单金琼(文\图) 不详

上期我们讲了抗螨蜜蜂的选育以及取得的成效,本期我们继续讨论选育抗螨蜜蜂过程中遇到的问题及建议。一、种蜂王的用户调查对目前蜂王市场的调查显示,客户的期望值很高,但满意度一般。欧洲养蜂人希望买到高品质的蜂王,其中最重要的是抗... 详细信息

上期我们讲了抗螨蜜蜂的选育以及取得的成效,本期我们继续讨论选育抗螨蜜蜂过程中遇到的问题及建议。一、种蜂王的用户调查对目前蜂王市场的调查显示,客户的期望值很高,但满意度一般。欧洲养蜂人希望买到高品质的蜂王,其中最重要的是抗病和高产。但是,他们对抗病性的满意度最低(图1)。近50%的用户认为选择育种是实现免用药养蜂的重要甚至唯一的手段。具有悠久育种传统的国家的用户对选择育种的认可率更高。

关键词：选择育种用户调查蜂王问题及建议抗螨养蜂人蜜蜂商业养蜂

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Serum omentin-1 is correlated with the severity of liver disease in patients with chronic hepatitis c

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World Journal of Hepatology 2023年第12期15卷 1315-1324页

作者： Georg Peschel Kilian Weigand Jonathan Grimm Martina Müller christa buechler Department of Internal Medicine I University Hospital RegensburgRegensburg 93053Germany Department of Internal Medicine Klinikum FürstenfeldbruckFürstenfeldbruck 82256Germany Department of Gastroenterology Gemeinschaftsklinikum MittelrheinKoblenz 56073Germany

BAcKGROUND Patients with chronic hepatitis c virus(HcV)infection have increased serum ***-1 is an anti-inflammatory adipokine,and higher levels may be a direct effect of HcV *** elimination of HcV by direct acting antivirals almost normalized circulating levels of various molecules with a role in *** To evaluate the effect of HcV infection on serum omentin-1,serum omentin-1 levels of HcV patients were measured before therapy and at 12 wk after therapy *** of serum omentin-1 with parameters of inflammation and liver function were explored at both time *** omentin-1 levels of patients with and without liver cirrhosis,which was defined by ultrasound or the fibrosis-4(FIB-4)score,were *** Serum omentin-1 levels were measured by enzyme-linked immunosorbent assay in 84 chronic HcV patients before therapy and at 12 wk after therapy end where sustained virological response 12(SVR12)was achieved in all *** omentin-1 of 14 non-infected controls was measured in *** In patients with chronic HcV,serum omentin-1 levels were not related to viral load or viral *** patients with liver steatosis and HcV patients with diabetes had serum omentin-1 levels comparable to patients not suffering from these *** omentin-1 levels at SVR12 were similar in comparison to pretreatment *** addition,serum levels did not differ between HcV-infected patients and non-infected *** omentin-1 levels did not correlate with leukocyte count or c-reactive *** correlations of serum omentin-1 with bilirubin and the model for end-stage liver disease score(MELD)were detected before therapy and at SVR12 in the whole *** and the MELD score also positively correlated with serum omentin-1 levels in the subgroup of patients with ultrasound diagnosed liver cirrhosis before *** SVR12,serum omentin-1 levels of patients with liver cirrhosis negativel

关键词： Direct acting antivirals Hepatitis c Liver cirrhosis Adipokine

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EurBeST——在商业养蜂条件下测试抗螨蜜蜂的中试研究

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中国蜂业 2024年第1期75卷 29-30页

作者： R.buechler(文/图) A.Uzunov(文/图) c.costa(文/图) M.Meixner(文/图) Y.Le conte(文/图) F.Mondet(文/图) M.Kovacic(文/图) S.Andonov(文/图) N.L.carreck(文/图) L.Dimitrov(文/图) B.Basso(文/图) M.Bienkowska(文/图) R.Dall’(文/图) Olio F.Hatjina(文/图) U.Wirtz(文/图) 陈超(文/图) 不详

根据官方报告,欧盟约有1600万群蜂、60万养蜂人,年生产蜂蜜价值近20亿欧元。除了直接生产蜂产品的价值外,蜜蜂还为农作物和野生植物授粉,有助于维护生物多样性和健康的农业生态系统。但是,农业生产的集约化、气候变化和全球化等导致一... 详细信息

根据官方报告,欧盟约有1600万群蜂、60万养蜂人,年生产蜂蜜价值近20亿欧元。除了直接生产蜂产品的价值外,蜜蜂还为农作物和野生植物授粉,有助于维护生物多样性和健康的农业生态系统。但是,农业生产的集约化、气候变化和全球化等导致一些蜂病的流行,给蜂群带来了巨大的压力。这其中包括寄生性的大蜂螨(Varroa destructor),如果不采取治疗措施,大多数蜂群在感染后一年内死亡。

关键词：农业生态系统大蜂螨寄生性蜂病蜂产品商业养蜂蜜蜂官方报告

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Practical Experiences in Manual Ultrasonic Phased Array Inspection

Practical Experiences in Manual Ultrasonic Phased Array Insp...

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17th World conference on Non-Destructive Testing

作者： Michael BERKE Johannes buechler GE Inspection Technologies GmbH HuerthGermany

＜正＞As with the transition from analog to digital Flaw Detectors in the 80th of the last century,manual phased array technique can again be understood as an important milestone in today’s ultrasonic *** to the successful use of ultrasonic phased array technology in medical diagnostics（～1970）and in automatic testing machines（～1995）,more and more applications can now be found in the field of manual *** of electronic components and improvements of processing speed allow the integration of phased array hardware into a small,battery driven instruments for fast ultrasonic imaging. The advantages of the phased array technique are obvious:B-scan,c-scan and S- scan in real time,easy understandable images with direct *** applications and their results will be described and images will be discussed including a comparison to the conventional technique.

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