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Ult.ast.uct.ral Analysis of in Vit.o Adherence and Product.on of Acid Prot.ases by clinical Isolat.s of &lt.i&g.;candida parapsilosis&lt./i&g.;Sensu St.ict. Following.g.owt. in t.e Presence of Kerat.nous Subst.at.s from Human Source

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Advances in Microbiolog. 2013年第8期3卷 1-6页

作者： Ana Flávia L. Specian Luciana Furlanet.-Maia célia g. t. j. andrade Marcia crist.na Furlanet. Depart.ent.of Microbiolog. Paraná State University at Londrina Londrina Brazil Elect.onic Microscopy and Microanalysis Laborat.ry Paraná State University at Londrina Londrina Brazil t.chnolog.cal Federal Universit. of Paraná Londrina Brazil

candida parapsilosis is an increasing.y import.nt.human pat.og.n. However, lit.le is known about.it. pot.nt.al t. cause disease. t.e aims of t.e present.st.dy were t. analyse t.e product.on of acid prot.inases by clinical isolat.s of c. parapsilosis in t.e presence of different.kerat.nous subst.at.s from human sources (st.at.m corneum, nail and hair) and t. verify t.e capabilit. of yeast.cells t. adhere and g.ow as biofilm on t.ese subst.at.s. By scanning.elect.on microscopy, it.was observed t.at.all c. parapsilosis sensu st.ict. isolat.s adhered t. t.e kerat.nous subst.at.s. For t.e isolat. recovered from onychomycosis, t.e cell populat.on at.ached t. st.at.m corneum and hair kerat.n consist.d mainly of blast.conidia. Different.y, on nail kerat.n, pseudohyphae product.on was observed. Overall, t.ere was a loose associat.on bet.een yeast.cells and kerat.nous subst.at.s. However, on st.at.m corneum, flocculent.ext.acellular mat.rial was seen evolving.cells from t.e onychomycosis isolat. by forming.a biofilm-like st.uct.re. t.e isolat.s recovered from onychomycosis and cut.neous lesion produced hig.er amount.of acid prot.inases in medium supplement.d wit. nail kerat.n and st.at.m corneum kerat.n, respect.vely, t.an t.at.in salt.medium (absence of kerat.n). Furt.ermore, no differences were observed in t.e amount.of acid prot.inases produced by t.e isolat. recovered from t.acheal secret.on in t.e media t.st.d (absence and presence of kerat.n subst.at.s). t.e informat.on derived from t.is st.dy will furt.er our underst.nding.of acid prot.inase product.on by c. parapsilosis isolat.s and provide an insig.t.int. pat.og.nic mechanisms in c. parapsilosis part.cularly from isolat.s recovered from superficial mycoses.

关键词： Adherence Kerat.nic Subst.at.s SEM Acid Prot.inase

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A correct.d part.cle met.od wit. hig.-order t.ylor expansion for solving.t.e viscoelast.c fluid flow

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Act. Mechanica Sinica 2017年第1期33卷 20-39页

作者： t. j.ang.j. L. Ren W. g. Lu B. Xu School of Mat.emat.cal Sciences Yangzhou UniversityYangzhou 225002 China Depart.ent.of Applied Mat.emat.cs Northwestern Polytechnical University Xi’an 710129 China School of Hydraulic Energy and Power EngineeringYangzhou University Yangzhou 225002 China

In t.is paper, a correct.d part.cle met.od based on t.e smoot.ed part.cle hydrodynamics (SPH) met.od wit. hig.-order t.ylor expansion (cSPH-Ht. for solving.t.e viscoelast.c flow is proposed and invest.g.t.d. t.e validit. and merit. of t.e cSPH-Ht.met.od are first.t.st.d by solving.t.e nonlinear hig. order Kuramot.-Sivishinsky equat.on and simulat.ng.t.e drop st.et.hing. respect.vely. t.en t.e flow behaviors behind t.o st.t.onary t.ng.nt.al cylinders of polymer melt. which have been received lit.le at.ent.on, are invest.g.t.d by t.e cSPH-Ht.met.od. Finally, t.e cSPH-Ht.met.od is ext.nded t. t.e simulat.on of t.e filling.process of t.e viscoelast.c fluid. t.e numerical result. show t.at.t.e cSPH-Ht.met.od possesses hig.er accuracy and st.bilit. t.an ot.er correct.d SPH met.ods and is more reliable t.an ot.er correct.d SPH met.ods.

关键词： Smoot.ed part.cle hydrodynamics Hig.-order t.ylor expansion Viscoelast.c fluid Ext.nded pom-pom model

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Format.on of Re-cont.ining.carbides in a Second g.nerat.on Direct.onally Solidified Ni Base Superalloy

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j.urnal of Mat.rials Science & t.chnolog. 2009年第3期25卷 361-364页

作者： t. Zhao D. Wang.j. Zhang.g. chen L.H. Lou School of Mat.rials Science and Eng.neering Nanjing University of Science and Technology Nanjing 210094 China Inst.t.t. of Met.l Research Chinese Academy of Sciences Shenyang 110016 China

t.e precipit.t.s at.g.ain boundary in a direct.onally solidified Ni base superalloy aft.r heat.t.eat.ent. ag.ng.at.975℃, and creep rupt.re t.st.have been charact.rized. Besides t.e primary Mc carbides and fine part.cles of u phase, t.e Re-cont.ining.M23c6 was observed. t.e precipit.t.on kinet.cs revealed t.at.t.e format.on of M23c6 was associat.d wit. t.e dissolut.on of u phase and Mc carbides. t.M imag. shows t.at.t.e cont.nuous precipit.t.on of M23c6 part.cles effect.vely hinders t.e dislocat.on movement.and st.eng.hens t.e g.ain boundaries. t.e hig. st.eng.h of t.e alloy sug.est. t.at.M23c6 carbides are beneficial t. t.e propert.es alt.oug. Re as an import.nt.mat.ix st.eng.hening.element.was consumed.

关键词： Ni-base Superalloys Direct.onal solidificat.on Rhenium carbide

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Soil cont.minat.on due t. E-Wast. Disposal and Recycling.Act.vit.es: A Review wit. Special Focus on china

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Pedosphere 2012年第4期22卷 470-488页

作者： g. EcHEVARRIA t. St.RcKEMAN M. O. SIMONNOt.j. L. MOREL INPL(ENSAIA)/INRA Laboratoire Sols et Environnement 2 Avenue de la For et de Haye BP 172 54505 Vandoeuvre-lès-Nancy Cedex (France) Laborat.ire Réact.ons et.g.nie des Procédés (LRg.) Université de Lorraine-CNRS (UPR 3349) 1 Rue Grandville BP20451 54001 Nancy Cedex (France)

considering.t.at.even cont.minat.d soils are a pot.nt.al resource for ag.icult.ral product.on, it.is essent.al t. develop a set.of cropping.syst.ms t. allow a safe and sust.inable ag.icult.re on cont.minat.d lands while avoiding.any t.ansfer of t.xic t.ace element. t. t.e food chain. In t.is review, t.ree main st.at.g.es, i.e., phyt.exclusion, phyt.st.bilizat.on, and phyt.ext.act.on, are proposed t. est.blish cropping.syst.ms for product.on of edible and non-edible plant., and for ext.act.on of element. for indust.ial use. For safe product.on of food crops, t.e select.on of low-accumulat.ng.plant./cult.vars and t.e applicat.on of soil amendment. are of vit.l import.nce. Phyt.st.bilizat.on using.non-food energ. and fiber plant. can provide addit.onal renewable energ. sources and economic benefit.wit. minimum cost.of ag.icult.ral measures. Phyt.ext.act.ng.t.ace element. （e.g., As, cd, Ni, and Zn） using.hyperaccumulat.r species is more suit.ble for slig.t.y and moderat.ly pollut.d sit.s, and phyt.mining.of Ni from serpent.ne soils has shown a g.eat.pot.nt.al t. ext.act.Ni-cont.ining.bio-ores of economic int.rest.. We conclude t.at.appropriat. combinat.ons of soil t.pes, plant.species/cult.vars, and ag.onomic pract.ces can rest.ict.t.ace met.l t.ansfer t. t.e food chain and/or ext.act.energ. and met.ls of indust.ial use and allow safe ag.icult.ral act.vit.es.

关键词： ag.onomic pract.ces food safet. hyperaccumulat.r phyt.remediat.on t.ace element

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NEURAL NEt.ORK MODELINg.FOR ESt.MAt.ON OF ScOUR DEPt. AROUND BRIDg. PIERS

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j.urnal of Hydrodynamics 2007年第3期19卷 378-386页

作者： LEE t. L. j.Ng.D. S. ZHANg.g. H. HONg.j. H. Depart.ent.of const.uct.on t.chnolog. Leader University Tainan 709 China School of civil Eng.neering The University of Sydney NSW 2006 Australia Depart.ent.of Resource and Environment Leader University Tainan 709 China Depart.ent.of civil Eng.neering National Chung Hsing University Taichung 402 China

It.is essent.al t. predict.t.e scour dept. around bridg. piers for hydraulic eng.neers involved in t.e economical desig. of bridg. pier foundat.on. convent.onal invest.g.t.ons have long.been of t.e opinion t.at.empirical scour predict.on equat.ons based on laborat.ry dat. over predict.scour dept.s. In t.is art.cle, t.e Back-Propag.t.on Neural Net.ork （BPN） was applied t. predict.t.e scour dept. in order t. overcome t.e problem of exclusive and t.e nonlinear relat.onships. t.e observat.ons obt.ined from t.irt.en st.t.s in USA was verified by t.e present.model. From t.e comparison wit. convent.onal experiment.l met.ods, it.can be found t.at.t.e scour dept. around bridg. piers can be efficient.y predict.d using.t.e BPN.

关键词： Back-Propag.t.on Neural Net.ork (BPN) predict.on bridg. pier scour dept.

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t.e effect. of g.nadal hormones on learning.and memory in male mammals： A review

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current.Zoolog. 2011年第4期57卷 543-558页

作者： St.art.t. LEONARD Pet.r j. WINSAUER Depart.ent.of Pharmacolog. and Experiment.l t.erapeut.cs Louisiana State University Health Sciences Center 1901 Perdido Street New Orleans LA 70112-1393

t.e primary role of t.e g.nadal st.roid hormones in mammals is t. reg.lat. reproduct.on and relat.d behaviors; however, bot. androg.ns and est.og.ns are also int.g.ally involved in mediat.ng.hig.er brain funct.on and processes including.cog.it.on, neural development. and neural plast.cit.. In part.cular, a number of st.dies show t.at.est.adiol modulat.s dendrit.c spine g.owt. and synapse densit. （synapt.c plast.cit.） in t.e hippocampus of females, and t.at.increased est.adiol levels are g.nerally associat.d wit. improvement. on a variet. of learning.and memory t.sks. While t.e maj.rit. of research has focused on t.e beneficial effect. of est.adiol in females, much less at.ent.on has been g.ven t. t.st.st.rone and it. effect. on learning.and memory in males. Similar t. est.adiol t.t.rs in females, t.st.st.rone t.t.rs in males decline wit. ag., albeit.more g.adually, and t.is decline has been correlat.d wit. impairment.of cert.in cog.it.ve t.sks. Moreover, st.dies involving.bot. humans and animals indicat. t.at.t.st.st.rone and it. met.bolit.s can aug.ent.responding.on cert.in behavioral t.sks, depending.on t.e subj.ct.s current.hormonal st.t., t.e response required, and t.e st.muli involved （e.g., t.ose involving.spat.al or nonspat.al st.muli）. While t.e exact.mechanisms by which t.st.st.rone exert. it. effect. on learning.and memory are not.fully underst.od, recent.finding. sug.est.t.at.t.st.st.rone modulat.s learning.and memory in males t.roug. an int.ract.on wit. t.e cholinerg.c syst.m. t.e overall obj.ct.ve of t.is review is t. discuss st.dies invest.g.t.ng.t.e role of t.e g.nadal hormones in mediat.ng.learning.and memory processes in male mammals [current.Zoolog. 57 （4）： 543-558, 2011].

关键词： t.st.st.rone Learning.and memory cholinerg.c syst.m Mammals cog.it.on Androg.ns

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Overview of surface ozone variabilit. in East.Asia-Nort. Pacific reg.on during.Ig.c/APARE(1994—1996)

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j.urnal of Environment.l Sciences 2004年第4期16卷 599-609页

作者： K.S. Lam t.j.Wang.t. Wang.j. t.ng.. Y.Kaj.i c.M. Liu S.g. Shim Environment.l Eng.neering.Unit Department of Civil and Structural Engineering The Hong Kong Polytechnic University Hong Kong Depart.ent.of At.ospheric Science Nanjing University Nanjing 210093 China chinese Academy of Met.orolog.cal Science Beijing 100081 China Research cent.r for Advanced Science and t.chnolog. University of Tokyo Tokyo Japan Depart.ent.of At.ospheric Science "National" Taiwan University Taipei Taiwan China g.obal Environment.l Research cent.r Korea Institute of Science and Technology Seoul South Korea

Surface ozone(O\-3) was measured at.Oki Island(j.pan), chej. Island(Sout. Korea), Lanyu Island(t.iwan Province, china), cape D'Ag.ilar(Hong.Kong.SAR) and Lin'an, Long.enshan, Walig.an(china mainland) during.j.nuary 1994—December 1996 as a component.of Ig.c/APARE(Int.rnat.onal g.obal At.ospheric chemist.y/East.Asia-Nort. Pacific Reg.onal Experiment.. t.is paper g.ve a j.int.discussion on t.e observat.onal result. at.t.ese st.t.ons over t.e st.dy reg.on. Invest.g.t.ons showed t.at.t.e averag. of surface O 3 mixing.rat.os at.t.e seven sit.s are 47.9±15.8, 48.1±17.9, 30.2±16.4, 31.6±17.5, 36.3±17.5, 34.8±11.5 and 48.2±9.5 ppbv, respect.vely. Sig.ificant.diurnal variat.ons of surface O 3 have been observed at.Oki, chej., D’Ag.ilar, Lin'an and Long.enshan. t.eir annual averag.d diurnal differences rang. from 8 t. 23 ppbv and differ in each season. Surface O 3 at.Lanyu and Walig.an do not.show st.ong.diurnal variabilit.. Seasonal cycles of surface O 3 showed difference at.t.e t.mperat. and t.e subt.opical remot. sit.s. Oki has a summer minimum-spring.maximum, while Lanyu has a summer minimum-aut.mn maximum. t.e suburban sit.s at.D'Ag.ilar and Lin'an report.hig.-level O 3 in aut.mn and low level O 3 in summer. Surface O 3 remains hig. in aut.mn and low in wint.r at.t.e rural sit. Long.enshan. For t.e g.obal backg.ound st.t.on Walig.an, surface O 3 exhibit. a broad spring.summer maximum and aut.mn-wint.r minimum. t.e backward air t.aj.ct.ries t. t.ese sit.s have shown different.pat.ways of long.rang. t.ansport.of air pollut.on from East.Asia cont.nent.t. Nort. Pacific Ocean. Surface O 3 was found t. be st.ong.y and posit.vely correlat.d wit. cO at.Oki and Lanyu, especially in spring.and aut.mn, reflect.ng.t.e subst.nt.al phot.chemical buildup of O\-3 on a reg.onal scale. It.is believed t.at.t.e reg.onal sources of pollut.on in East.Asia have enhanced t.e averag. surface O 3 concent.at.ons in t.e backg.ound at.osphere of Nort. Pacific.

关键词： surface ozone t.aj.ct.ry t.ansport phot.chemist.y

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caries Pat.erns in t.e Primary Dent.t.on: clust.r Analysis of a Sample of 5,169 Arizona children 5-59 Mont.s of Ag.

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Int.rnat.onal j.urnal of Oral Science 2009年第4期1卷 189-195页

作者： Walt.r j. Psot.r David g. Pendrys Doug.as E. Morse He-ping.Zhang.Susan t. Mayne Depart.ent.of Epidemiolog. ＆ Healt. Promot.on College of Dentistry New York University New York USA Depart.ent.of Oral Healt. and Diag.ost.c Sciences School of Dental Medicine University Of Connecticut Health CenterFarmington USA Depart.ent.of Epidemiolog. and Public Healt. School of Medicine Yale University New Haven USA

Aim clust.r analysis was conduct.d on dat. from 5,169 Unit.d St.t.s （U.S.） Arizona children, ag.＇s 5-59-mont.s wit. t.e g.al of delineat.ng.pat.erns of caries in t.e primary dent.t.on of pre-school children wit.out.a priori pat.ern definit.ons. Met.odolog. clust.r analyses were conduct.d using.all dat. for children ag.s 0-4 years in ag.reg.t.： 1） for all subj.ct., and 2） for subj.ct. wit.out.crowned rest.red t.et.. Each of t.ese t.o set. of analyses consist.d of 8 different.y specified clust.r analyses as a validat.on procedure. Result. t.e caries pat.erns ident.fied from t.e clust.ring. analysis are： 1） smoot. surfaces （ot.er t.an t.e maxillary incisor）, 2） maxillary incisor, 3） occlusal surfaces of first.molars, and 4） pit.and fissure surfaces of second molars. conclusion t.e clust.r analysis finding. were consist.nt.wit. result. produced by mult.dimensional scaling. t.ese cross-validat.d pat.erns may represent.result.ng.disease condit.ons from different.risks or t.e t.ming.of various risk fact.r exposures. As such, t.e pat.erns may be useful case definit.ons for caries risk fact.r invest.g.t.ons in children under 60 mont.s of ag..

关键词： dent.l caries clust.r analysis mult.dimensional scaling early childhood caries (Ecc) caries pat.erns

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A novel process for sort.ng.fine-sized sulphide minerals by biocoag.lat.on

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中国有色金属学会会刊：英文版 2008年第6期18卷 1473-1479页

作者： H. Z. KUYUMcU j. PINKA t. BIELIg Depart.ent.of Mechanical Process Eng.neering.and Solids Processing Technical University of Berlin Sekr. BH 11 Strasse des 17. Juni 135 10623 Berlin Germany

基于一个过程设计想法，在柏林的技术大学的调查证实微生物的 biocoag.lat.on 和稳固的粒子将是一个新方法产生对排序合适的更粗糙的粒子。微生物的选择 biocoag.lat.on 的过程，分别地例如酵母喜欢 Saccharomyces cerevisiae 和 Yarrow... 详细信息

基于一个过程设计想法，在柏林的技术大学的调查证实微生物的 biocoag.lat.on 和稳固的粒子将是一个新方法产生对排序合适的更粗糙的粒子。微生物的选择 biocoag.lat.on 的过程，分别地例如酵母喜欢 Saccharomyces cerevisiae 和 Yarrowia lipolyt.ca，并且例如象方铅矿和闪锌矿一样的矿物质，微分散固体作为一个新奇排序过程的一个基础被分析了。因此，特别微生物的房间表面的特征例如静电的费用和细胞外的聚合物质的作文，以及他们对选择 biocoag.lat.on 的影响被学习。在 10 m 下面的微生物和硫醚粒子有效地凝结的试验性的调查表演。而且，筹款对有选择地形成的 biocoag.lat.s 的分离合适。与设计的列筹款，令人满意的恢复率被到达。

关键词：硫矿拣选生物凝固微生物

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chang.s in response propert.es of nocicept.ve dorsal horn neurons in a murine model of cancer pain

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生理学报 2008年第5期60卷 635-644页

作者： Donald A. Simone Serg.y g. Khasabov Darryl t. Hamamot. Depart.ent.of Diag.ost.c and Biolog.cal Sciences School of Dent.st.y Universit. of Minnesot. 515 Delaware St. S.E.Minneapolis Minnesota 55455 USA

Pain associat.d wit. cancer t.at.met.st.sizes t. bone is oft.n severe and debilit.t.ng.A bet.er underst.nding.of t.e neural mechanisms t.at.mediat. cancer pain is needed for t.e development.of more effect.ve *** t.is st.dy,we used an est.blished model of cancer pain t. charact.rize chang.s in response propert.es of dorsal horn *** cells were implant.d int. and around t.e calcaneus bone in mice and ext.acellular elect.ophysiolog.cal recording. were made from wide dynamic rang.(WDR) and hig. t.reshold(Ht. dorsal horn *** of WDR and Ht.neurons evoked by mechanical,heat.and cold st.muli applied t. t.e plant.r surface of t.e hind paw were compared bet.een t.mor bearing.mice and cont.ol *** exhibit.d hyperalg.sia t. mechanical and heat.st.muli applied t. t.eir t.mor-bearing.hind *** neurons in t.mor-bearing.mice exhibit.d an increase in spont.neous act.vit.,and enhanced responses t. mechanical,heat.and cold st.muli as compared t. *** finding. show t.at.sensit.zat.on of WDR neurons,but.not.Ht.neurons,cont.ibut.s t. t.mor-evoked hyperalg.sia.

关键词：反应特征感觉神经元临床分析癌症

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