检索结果-南通市图书馆

稳定型咬合板治疗伴偏侧咀嚼单侧不可复性盘前移位患者MRI研究

在线全文

学校读者我要写书评

暂无评论

中华老年口腔医学杂志 2024年第2期22卷 95-100页

作者：徐鑫宇黄东宗王岩刘刚胡一帆胡敏刘洪臣姜华解放军总医院第一医学中心口腔修复科北京100853 解放军总医院第一医学中心放射诊断科北京100853 解放军总医院第一医学中心口腔颌面外科北京100853 解放军总医院口腔医学研究所口腔颌面战创伤军队重点实验室口腔颌面修复军队医学重点实验室

目的通过MRI评估稳定型咬合板治疗伴偏侧咀嚼单侧不可复性盘前移位患者的疗效。方法选取在解放军总医院第一医学中心口腔科就诊,经过临床检查及影像学检查诊断为单侧不可复性颞下颌关节盘前移位患者34例,根据其是否存在偏侧咀嚼习惯,将... 详细信息

目的通过MRI评估稳定型咬合板治疗伴偏侧咀嚼单侧不可复性盘前移位患者的疗效。方法选取在解放军总医院第一医学中心口腔科就诊,经过临床检查及影像学检查诊断为单侧不可复性颞下颌关节盘前移位患者34例,根据其是否存在偏侧咀嚼习惯,将其分为伴偏侧咀嚼组(17例)和无偏侧咀嚼组(17例),分析患者最大开口度、疼痛指数、关节盘长度、盘分界角、关节盘位置以及翼外肌特点。采用SPSS25.0软件对结果进行统计分析。结果稳定型咬合板治疗前,伴偏侧咀嚼(chewing side preference,CSP)组患者同侧关节盘-髁突角度(61.13±10.54°)大于无CSP组(51.12±17.27°);伴CSP组同侧、对侧关节盘-髁突角度差值(52.52±10.91°)大于无CSP组差值(41.26±17.78°);伴CSP组同侧、对侧翼外肌下头面积差值(-0.43±3.66mm2)小于无CSP组同侧、对侧翼外肌下头面积差值(0.288±4.57mm2),差异均有统计学意义(P0.05);稳定型咬合板治疗后两组患者关节盘-髁突角度、关节盘长度减小,差异均有统计学意义(P0.05)。两组稳定型咬合板治疗后翼外肌上、下头长度、厚度和面积的平均值接近,差异无统计学意义(P>0.05)。Logistic回归分析显示,MMO(OR=0.743)与偏侧咀嚼存在相关性(P<0.05)。结论MRI能无创诊断ADDWoR,伴CSP的单侧ADDWoR患者患侧关节移位更加显著,且单侧ADDWoR患者MMO与CSP存在相关性,通过稳定型咬合板治疗能显著改善ADDWoR患者开口度及疼痛症状,缓解关节盘受压及关节盘移位程度。

关键词：稳定型咬合板不可复性颞下颌关节盘前移位偏侧咀嚼 MRI

Serum ceruloplasmin can predict liver fibrosis in hepatitis B virusinfected patients

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2020年第27期26卷 3952-3962页

作者： Na-Ling Kang Jie-min Zhang Meng-Xin Lin Xu-Dong Chen Zu-Xiong Huang yue-Yong Zhu yu-Rui Liu Da-Wu Zeng Liver Center The First Affiliated HospitalFujian Medical UniversityFuzhou 350005Fujian ProvinceChina Department of Pharmacy The First Affiliated HospitalFujian Medical UniversityFuzhou 350005Fujian ProvinceChina Department of Infectious Diseases The First Hospital of Quanzhou Affiliated with Fujian Medical UniversityQuanzhou 362000Fujian ProvinceChina Department of Gastroenterology the 910th Hospital of the People's Liberation ArmyQuanzhou 362000Fujian ProvinceChina Hepatology Mengchao Hepatobiliary Hospital of Fujian Medical UniversityFuzhou 350005Fujian ProvinceChina

BACKGROUND The presence of significant liver fibrosis in hepatitis B virus(HBV)-infected individuals with persistently normal serum alanine aminotransferase(PNALT)levels is a strong indicator for initiating antiviral *** ceruloplasmin(CP)is negatively correlated with liver fibrosis in HBV-infected *** To examine the potential value of serum CP and develop a noninvasive index including CP to assess significant fibrosis among HBV-infected individuals with *** Two hundred and seventy-five HBV-infected individuals with PNALT were retrospectively *** association between CP and fibrotic stages was statistically analyzed.A predictive index including CP[Ceruloplasmin hepatitis B virus(CPHBV)]was constructed to predict significant fibrosis and compared to previously reported *** Serum CP had an inverse correlation with liver fibrosis(r=-0.600).Using CP,the areas under the curves(AUCs)to predict significant fibrosis,advanced fibrosis,and cirrhosis were 0.774,0.812,and 0.853,*** CPHBV model was developed using CP,platelets(PLT),and HBsAg levels to predict significant *** AUCs of this model to predict significant fibrosis,advanced fibrosis,and cirrhosis were 0.842,0.920,and 0.904,*** was superior to previous models like the aspartate aminotransferase(AST)-to-PLT ratio index,Fibrosis-4 score,gamma-glutamyl transpeptidase-to-PLT ratio,Forn’s score,and S-index in predicting significant fibrosis in HBV-infected individuals with *** CPHBV could accurately predict liver fibrosis in HBV-infected individuals with ***,CPHBV can be a valuable tool for antiviral treatment decisions.

关键词： Ceruloplasmin Liver fibrosis Chronic hepatitis B infection Serum alanine aminotransferase Noninvasive model Receiver-operating characteristic

Interactions between phosphorus availability and microbes in a wheat–maize double cropping system:A reduced fertilization scheme

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2022年第3期21卷 840-854页

作者： yu Xiao-jing CHEN Qi SHI Wen-cong GAO Zheng SUN Xiao DONG Jing-jing LI Juan WANG Heng-tao GAO Jian-guo LIU Zhi-guang ZHANG min National Engineering Research Center for Efficient Utilization of Soil and Fertilizer Resources/College of Resources and Environment/College of Life Sciences Shandong Agricultural UniversityTai’an 271018P.R.China Key Laboratory of Plant Nutrition and Fertilizer Ministry of Agriculture and Rural Affairs/Institute of Agricultural Resources and Regional PlanningChinese Academy of Agricultural SciencesBeijing 100081P.R.China Shandong Zhongxin Agricultural Development Co. Ltd.Linshu 276700P.R.China

Mechanisms controlling phosphorus(P) availability and the roles of microorganisms in the efficient utilization of soil P in the wheat–maize double cropping system are poorly *** the present study,we conducted a pot experiment for four consecutive wheat–maize seasons(2016–2018) using calcareous soils with high(30.36 mg kg^(–1)) and low(9.78 mg kg^(–1)) initial Olsen-P content to evaluate the effects of conventional P fertilizer application to both wheat and maize(Pwm) along with a reduced P fertilizer application only to wheat(Pw).The microbial community structure along with soil P availability parameters and crop yield were *** results showed that the Pw treatment reduces the annual P input by 33.3% without affecting the total yield for at least two consecutive years as compared with the Pwm treatment in the high Olsen-P *** water-soluble P concentrations in the Pw treatment were similar to those in the Pwm treatment at the 12-leaf collar stage when maize requires the most ***,the soil P content significantly affected soil microbial communities,especially fungal ***,the relative abundances of Proteobacteria and alkaline phosphatase(ALP) activity of Pw were significantly higher(by 11.4 and 13.3%) than those of Pwm in soil with high *** microfloral contribution to yield was greater than that of soil P content in soil with high *** abundances of Bacillus and Rhizobium were enriched in the Pw treatment compared with the Pwm *** showed a significant positive correlation with acid phosphatase(ACP) activity,and Rhizobium displayed significant positive correlations with ACP and ALP in soil with high Olsen-P,which may enhance P *** findings suggested that the application of P fertilization only to wheat is practical in high P soils to ensure optimal production in the wheat and maize double cropping system and that the soil P availability and microbial community may collabo

关键词： wheat–maize rotation Olsen-P alkaline phosphatase phosphorus fertilization calcareous soils

Rapid screening for Klinefelter syndrome with a simple high-resolution melting assay： a multicenter study

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2018年第4期20卷 349-354页

作者： Dong-Mei Fu yu-Lin Zhou Jing Zhao Ping HU Zheng-Feng Xu3 Shi-ming Lv Jun-Jie HU Zhong-min Xia Qi-Wei Guo United Diagnostic and Research Center for Clinical Genetics School of Public Health of Xiamen University and Xiamen Maternal and Child Health Hospital Xiamen 361003 China Xiamen Kingnova Biological Technology Co. Ltd. Xiamen 361028 China Center of Medical Genetics Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University Nanjing 210029 China Clinical Analysis Center Women's Hospital School of Medicine Zhejiang University Hangzhou 310006 China

Klinefelter syndrome （KS） is the set of symptoms that result from the presence of an extra X chromosome in males. Postnatal population-based KS screening will enable timely diagnosis of this common chromosomal disease, providing the opportunity for early intervention and therapy at the time point when they are most effective and may prevent later symptoms or complications. Therefore, through this study, we introduced a simple high-resolution melting （HRM） assay for KS screening and evaluated its clinical sensitivity and specificity in three medical centers using 1373 clinical blood samples. The HRM assay utilized a single primer pair to simultaneously amplify specific regions in zinc finger protein, X-linked （ZFX） and zinc finger protein, Y-linked （ZFY）. In cases of KS, the ratios of ZFX/ZFYare altered compared to those in normal males. As a result, the specific melting profiles differ and can be differentiated during data analysis. This HRM assay displayed high analytical specificity over a wide range of template DNA amounts （5 ng-50 ng） and reproducibility, high resolution for detecting KS mosaicism, and high clinical sensitivity （100%） and specificity （98.1%）. Moreover, the HRM assay was rapid （2 h per run）, inexpensive （0.2 USD per sample）, easy to perform and automatic, and compatible with both whole blood samples and dried blood spots. Therefore, this HRM assay is an ideal postnatal population-based KS screening tool that can be used for different age groups.

关键词： high-resolution melting Klinefelter syndrome multicenter study postnatal population-based screening

超声辅助复合酶法提取板栗仁中可溶性膳食纤维工艺优化及其结构表征

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

河北科技师范学院学报 2024年第1期38卷 48-54,61页

作者：余祚庆彭飞俞禧杨越冬河北省天然产物活性成分与功能重点实验室河北科技师范学院河北秦皇岛066004

以燕山板栗为原料,采用超声辅助复合酶法提取板栗膳食纤维。通过单因素试验考察复合酶(m(α-淀粉酶)∶m(糖化酶)=4∶1)添加量、中性蛋白酶添加量和超声波处理时间对板栗膳食纤维得率的影响,设计响应面试验对酶解工艺中各影响因素进行优... 详细信息

以燕山板栗为原料,采用超声辅助复合酶法提取板栗膳食纤维。通过单因素试验考察复合酶(m(α-淀粉酶)∶m(糖化酶)=4∶1)添加量、中性蛋白酶添加量和超声波处理时间对板栗膳食纤维得率的影响,设计响应面试验对酶解工艺中各影响因素进行优化,并采用扫描电镜、红外光谱和热质量分析对其结构进行表征。结果表明,以板栗的质量计量,超声辅助复合酶法提取膳食纤维最佳条件为:复合酶添加量为11%,中性蛋白酶添加量为4%,超声波处理时间15 min。在此条件下,板栗膳食纤维得率为22.22%。扫描电镜显示板栗膳食纤维呈现松散的片状或层状结构,表面具有较多的孔洞。红外光谱显示其具有膳食纤维的特征吸收峰。热质量分析板栗膳食纤维适合在400℃以下温度加工。超声辅助复合酶法能有效用于板栗中膳食纤维的提取。

关键词：板栗膳食纤维提取工艺超声辅助复合酶法结构表征

Therapeutic Effects of Sodium Hyaluronate on Ocular Surface Damage Induced by Benzalkonium Chloride Preserved Anti-glaucoma Medications

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2015年第18期128卷 2444-2449页

作者： Xing Liu Fen-Fen yu Yi-min Zhong Xin-Xing Guo Zhen Mao Department of Glaucoma The State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-sen University Guangzhou Guangdong 510060 China Department of Ophthalmology First Affiliated Hospital Sun Yat-sen University Guangzhou Guangdong 510080 China

Background： Long-term use of benzalkonium chloride （BAC）-preserved drugs is often associated with ocular surface toxicity. Ocular surface symptoms had a substantial impact on the glaucoma patients＇ quality of life and compliance. This study aimed to investigate the effects of sodium hyaluronate （SH） on ocular surface toxicity induced by BAC-preserved anti-glaucoma medications treatment. Methods： Filly-eight patients （101 eyes）, who received topical BAC-preserved anti-glaucoma medications treatment and met the severe dry eye criteria, were included in the analysis. All patients were maintained the original topical anti-glaucoma treatment. In the SH-treated group （56 eyes）, unpreserved 0.3% SH eye drops were administered with 3 times daily for 90 days. In the control group （55 eyes）, phosphate-butTered saline were administered with 3 times daily for 90 days. Ocular Surface Disease Index （OSDI） questionnaire, break-up time （BUT） test, corneal fluorescein staining, corneal and conjunctival rose Bengal staining, Schirmer test, and conjunctiva impression cytology were pertbrmed sequentially on days 0 and 91. Results： Compared with the control group, SH-treated group showed decrease in OSDI scores （Kruskal-Wallis test： H = 38.668, P 〈 0.001 ）, fluorescein and rose Bengal scores （Wilcoxon signed-ranks test： z = -3.843, P 〈 0.001, and z = 3.508, P 〈 0.001, respectively）, increase in tear fihn BUT （t-test： t - -10.994, P 〈 0.001 ） and aqueous tear production （t-test： t = -10.328, P 〈 0.001 ） on day 91. The goblet cell density was increased （t-test： t = -9.981, P 〈 0.001）, and the morphology of the conjunctival epithelium were also improved after SH treatment. Conclusions： SH significantly improved both symptoms and signs of ocular surface damage in patients with BAC-preserved anti-glaucoma medications treatment. SH could be proposed as a new attempt to reduce ocular surface toxicity, and alleviate symptoms of ocular surface damage in BAC-preserved anti-glaucoma medications tr

关键词： Anti-glaucoma Medications Benzalkonium Chloride Ocular Surface Toxicity Sodium Hyaluronate

临时造口患者造口接受度现状及其与自我管理行为的关系研究

在线全文

学校读者我要写书评

暂无评论

护士进修杂志 2024年第8期39卷 785-789,794页

作者：王汐嬅绳宇李敏程悦郭淑丽肖毅侯文红张冠南牛备战中国医学科学院北京协和医院北京100730 中国医学科学院北京协和医学院北京100144

目的了解临时造口患者的造口接受度现状,分析其影响因素及其与自我管理行为的关系。方法采用便利抽样法,选取2022年3-11月在北京协和医院普外科行临时造口患者126例,采用一般资料调查表、造口自我管理行为问卷、中文版造口接受度问卷进... 详细信息

目的了解临时造口患者的造口接受度现状,分析其影响因素及其与自我管理行为的关系。方法采用便利抽样法,选取2022年3-11月在北京协和医院普外科行临时造口患者126例,采用一般资料调查表、造口自我管理行为问卷、中文版造口接受度问卷进行问卷调查。结果临时造口患者中文版造口接受度问卷总分为(33.52±2.92)分,条目均分为(2.79±0.73)分,处于中等水平。单因素分析结果显示:不同年龄、文化程度、保留造口时间、主要照顾者及有无合并症对患者造口接受度有影响(P<0.05);Pearson相关性分析结果显示:造口接受度总分与自我管理行为总分及其5个维度均呈正相关(r=0.589、0.617、0.178、0.235、0.416、0.306,P<0.05);多元线性回归分析显示:文化程度、有无合并症及自我管理行为中造口护理维度是造口接受度的影响因素(P<0.01)。结论临时造口患者回归社会后的心理状态是医护人员亟待关注的问题,其造口接受度处于中等水平,可根据影响因素构建有效干预措施提高患者造口接受度,促进自我管理行为,帮助其顺利适应造口生活。

关键词：临时造口接受度自我管理行为影响因素相关性检验护理

基于改进结构保持数据降维方法的故障诊断研究

在线全文

学校读者我要写书评

暂无评论

自动化学报 2021年第2期47卷 338-348页

作者：韩敏李宇韩冰大连理工大学电子信息与电气工程学部大连116023 上海船舶航运研究院航海与安全技术国家重点实验室上海200135

传统基于核主成分分析(Kernel principal component analysis,KPCA)的数据降维方法在提取有效特征信息时只考虑全局结构保持而未考虑样本间的局部近邻结构保持问题,本文提出一种改进全局结构保持算法的特征提取与降维方法.改进的特征提... 详细信息

传统基于核主成分分析(Kernel principal component analysis,KPCA)的数据降维方法在提取有效特征信息时只考虑全局结构保持而未考虑样本间的局部近邻结构保持问题,本文提出一种改进全局结构保持算法的特征提取与降维方法.改进的特征提取与降维方法将流形学习中核局部保持投影(Kernel locality preserving projection,KLPP)的思想融入核主成分分析的目标函数中,使样本投影后的特征空间不仅保持原始样本空间的整体结构,还保持样本空间相似的局部近邻结构,包含更丰富的特征信息.上述方法通过同时进行的正交化处理可避免局部子空间结构发生失真,并能够直观显示出低维结果,将低维数据输入最近邻分类器,以识别率和聚类分析结果作为衡量指标,同时将所提方法应用于故障诊断中.使用AVL Boost软件模拟的柴油机故障数据和田纳西(Tennessee Eastman,TE)化工数据仿真,验证了所提方法的有效性.

关键词：特征提取数据降维核主成分分析局部保持投影法故障诊断

APPLICATION OF MICROWAVE IRRADIATION TO THE SYNTHESIS OF SOME ALKALI METAL METAVANADATES

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 1992年第2期3卷 109-110页

作者： Wen Guo XU~*, Ai min yu, Jun LIU Department of chemistry, Jilin University, Changchun, 130023

Application of microwave irradiation to the syhthesis of some alkali metal metavanadates in a fraction of time required by the conventional synthetic method (2min for LiVO_3, 3.5min for NaVO_3) is described.

关键词： der