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Fabricating Na/In/C Composite Anode with Natrophilic Na-In Alloy Enables Superior Na Ion Deposition in the EC/PC Electrolyte

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Nano-Micro Letters 2022年第2期14卷 45-59页

作者： Hui Wang Yan Wu Ye Wang Tingting Xu Dezhi Kong Yang Jiang Di Wu Yongbing Tang Xinjian Li Chun-Sing lee Key Laboratory of Material Physics of Ministry of Education School of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052People’s Republic of China Department of Chemistry Center of Super‑Diamond and Advanced Films(COSDAF)City University of Hong KongHong Kong SAR 999077People’s Republic of China School of Materials Science and Engineering Hefei University of TechnologyHefei 230009AnhuiPeople’s Republic of China Shenzhen Institutes of Advanced Technology Chinese Academy of SciencesShenzhen 518055People’s Republic of China

In conventional ethylene carbonate(EC)/propylene carbonate(PC)electrolyte,sodium metal reacts spontaneously and deleteriously with solvent *** significantly limits the practical feasibility of high-voltage sodium metal batteries based on Na metal ***,we present a sodium metal alloy strategy via introducing NaIn and Na_(2)In phases in a Na/In/C composite,aiming at boosting Na ion deposition stability in the common EC/PC *** cells with Na/In/C electrodes achieve an impressive long-term cycling capability at 1 mA cm^(-2)(>870 h)and 5 mA cm^(-2)(>560 h),respectively,with a capacity of 1 mAh cm^(-2).In situ optical microscopy clearly unravels a stable Na ion dynamic deposition process on the Na/In/C composite electrode surface,attributing to a dendrite-free and smooth ***,theoretical simulations reveal intrinsic mechanism for the reversible Na ion deposition behavior with the composite Na/In/C *** pairing with a highvoltage NaVPOF cathode,Na/In/C anode illustrates a better suitability in SMB *** work promises an alternative alloying strategy for enhancing Na metal interfacial stability in the common EC/PC electrolyte for their future applications.

关键词： EC/PC electrolyte Sodium metal batteries Na/In/C electrode Dendrite-free and smooth morphology Theoretical simulations

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A survey of arsenic and other heavy metals in vegetation from markets or mine tailings

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Journal of Environmental Sciences 2006年第2期18卷 287-291页

作者： LIU Wen-ju Kim Kyoung-woong ZHU Yong-guan lee Sang-woo CHANG Pei-chun Kwak Ji-hyun Department of Environmental Science and Engineering Gwangju Institute of Science and Technology （GIST） Gwangju 500-712 Korea Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Beijing 100085 China College of Natural Resources and Environment Hebei Agricultural University Baoding 071001 China

This research includes two investigations. The first one is a market basket survey of the levels of arsenic （As） and trace elements in bracken fern （Pteridium aquilinum） originated from three countries： South Korea, China and North Korea. The results showed that the mean As concentrations in stems of samples were significantly higher than those in leaves. As concentrations in all samples did not exceed food safety limits for vegetables. Generally, concentrations of Fe, Mn, Cu and Zn in leaves were higher than those in stems. The second investigation is a survey on the levels of As and other heavy metals in vegetation in the vicinity of Myoungbong mine tailings. The results demonstrated that As, Pb and Cu concentrations and bioaccumulation factors （BCF） in seedlings of the fern（A splenium achilleifolium） were the highest, whereas Marsh horsetail（Equisetum polustre） accumulated the highest levels of Zn. Concentrations of As, Pb, Zn and Cu in vegetable-cress （Lepidium sativum） and the edible herb-aromatic madder （Elasholtzia splendens） were higher than food safety limits. Therefore, a risk assessment of As and other heavy metals in vegetables and herbs on local human health should be conducted in the future.

关键词： arsenic heavy metals ferns bioaccumulation factors

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A Personalized Digital Code from Unique Genome Fingerprinting Pattern for Use in Identification and Application on Blockchain

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Computational Molecular Bioscience 2023年第1期13卷 1-20页

作者： Isaac Kise lee Eone Diagnomics Genome Center (EDGC) Incheon South Korea NGENI Foundation San Diego CA USA

With over 10 million points of genetic variation from person to person, every individual’s genome is unique and provides a highly reliable form of identification. This is because the genetic code is specific to each individual and does not change over time. Genetic information has been used to identify individuals in a variety of contexts, such as criminal investigations, paternity tests, and medical research. In this study, each individual’s genetic makeup has been formatted to create a secure, unique code that incorporates various elements, such as species, gender, and the genetic identification code itself. The combinations of markers required for this code have been derived from common single nucleotide polymorphisms (SNPs), points of variation found in the human genome. The final output is in the form of a 24 numerical code with each number having three possible combinations. The custom code can then be utilized to create various modes of identification on the decentralized blockchain network as well as personalized services and products that offer users a novel way to uniquely identify themselves in ways that were not possible before.

关键词： Genomic Fingerprint Digital Code SNP’s Auxiliary Code Marker Selection Blockchain Web3.0 Decentralized Identification (DID)

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SOME NEW SPECIES OF RHOPALOCERA IN CHINA, Ⅱ.

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昆虫学报 1962年第2期 144-158页

作者： lee CHUAN-LUNG

In the present paper, six new species and fourteen new subspecies of Chinese butter-flies belonging to 6 families and 16 genera are described. The butterflies here dealt with were collected by Chinese and Soviet entomologistsduring their joint expeditions to Southwest China (chiefly in S. and S.-W. Yunnan) in theyears 1955--1957. The characteristics of new species and subspecies are given as follows:

关键词：新种 SOME NEW SPECIES OF RHOPALOCERA IN CHINA 外生蝶类侧面观图版正面

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Computerized Control and Operation of Rutherford Backscattering/Channeling for an in situ Ion Beam System and Its Application for Measurement of Si（001） and ZnO（001）

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Chinese Physics Letters 2011年第1期28卷 66-69页

作者： HE Jun J. C. lee LI Ming WANG Ze-Song LIU Chuan-Sheng FU De-Jun Accelerator Laboratory Wuhan University Wuhan 430072 Quantum-Functional Semiconductor Research Center Dongguk University 3-26 Pildong Seoul 100-715 Korea

A computer-automated Rutherford backscattering/channeling （RBS/C） system is developed to provide in situ ion beam analysis of the accelerator-TEM system in Wuhan University. The basic system components are a PC equipped with a multichannel analyzer data acquisition board, motion control hardware including the Panmure stepping motor controller and integrated circuit modules, and a Labview programmed operating system with associated electronics. Single crystalline Si（001） and ZnO（001） implanted with Mn ions were characterized with this computerized setup. The crystalline quality Xmin and channeling half angle of Si（O01） were measured to be 4.65% and 0.52%, respectively, which are comparable to theoretical values 4.2% and 0.32%. The ion implantation induced damage depth profile derived from channeling and random spectrum is in reasonable agreement with the result calculated by the SRIM Monte-Carlo simulation code.

关键词： Surfaces interfaces and thin films Condensed matter: structural mechanical & thermal

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Sanger Sequencing for Molecular Diagnosis of SARS-CoV-2 Omicron Subvariants and Its Challenges

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Journal of Biosciences and Medicines 2022年第9期10卷 182-223页

作者： Sin Hang lee Milford Molecular Diagnostics Laboratory Milford USA

Large population passages of the SARS-CoV-2 in the past two and a half years have allowed the circulating virus to accumulate an increasing number of mutations in its genome. The most recently emerging Omicron subvariants have the highest number of mutations in the Spike (S) protein gene and these mutations mainly occur in the receptor-binding domain (RBD) and the N-terminal domain (NTD) of the S gene. The European Centre for Disease Prevention and Control (eCDC) and the World Health Organization (WHO) recommend partial Sanger sequencing of the SARS-CoV-2 S gene RBD and NTD on the polymerase chain reaction (PCR)-positive samples in diagnostic laboratories as a practical means of determining the variants of concern to monitor possible increased transmissibility, increased virulence, or reduced effectiveness of vaccines against them. The author’s diagnostic laboratory has implemented the eCDC/WHO recommendation by sequencing a 398-base segment of the N gene for the definitive detection of SARS-CoV-2 in clinical samples, and sequencing a 445-base segment of the RBD and a 490 - 509-base segment of the NTD for variant determination. This paper presents 5 selective cases to illustrate the challenges of using Sanger sequencing to diagnose Omicron subvariants when the samples harbor a high level of co-existing minor subvariant sequences with multi-allelic single nucleotide polymorphisms (SNPs) or possible recombinant Omicron subvariants containing a BA.2 RBD and an atypical BA.1 NTD, which can only be detected by using specially designed PCR primers. In addition, Sanger sequencing may reveal unclassified subvariants, such as BA.4/BA.5 with L84I mutation in the S gene NTD. The current large-scale surveillance programs using next-generation sequencing (NGS) do not face similar problems because NGS focuses on deriving consensus sequence.

关键词： eCDC WHO Sanger Sequencing Omicron Variant Minor Subvariants BA.4/BA.5 L84I BA.2 Multi-Allelic Recombinant

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Osteoblasts apoptosis is mediated through glycogen synthase kinase 3beta

Osteoblasts apoptosis is mediated through glycogen synthase ...

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International Conference on Osteoporosis and Bone Research 2008

作者： Yoon-Sok Chung Sun-il Yun Hyung-Young Yoon Ajou University School of Medicine SuwonRepublic of Korea

＜正＞Mechanisms controlling the survival of osteoblast cells are critical during bone development,in osteoporosis for bone turnover,and following side effects for drug treatment.

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Revealing the inhomogeneous surface chemistry on the spherical layered oxide polycrystalline cathode particles

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Chinese Physics B 2020年第2期29卷 81-86页

作者： Zhi-Sen Jiang Shao-Feng Li Zheng-Rui Xu Dennis Nordlund Hendrik Ohldag Piero Pianetta Jun-Sik lee Feng Lin Yi-Jin Liu College of Physics Sichuan UniversityChengdu 610065China Stanford Synchrotron Radiation Lightsource SLAC National Accelerator LaboratoryMenlo ParkCA 94025USA Department of Chemistry Virginia TechBlacksburgVA 24061USA

The hierarchical structure of the composite cathodes brings in significant chemical complexity related to the interfaces,such as cathode electrolyte *** interfaces account for only a small fraction of the volume and mass,they could,however,have profound impacts on the cell-level *** the investigation of these interfaces becomes a crucial topic in the battery research,there is a need to properly study the surface chemistry,particularly to eliminate the biased,incomplete characterization provided by techniques that assume the homogeneous surface ***,we utilize nano-resolution spatially-resolved x-ray spectroscopic tools to probe the heterogeneity of the surface chemistry on LiNi0.8Mn0.1Co0.1O2 layered cathode secondary *** by the nano-resolution mapping of the Ni valance state,which serves as a measurement of the local surface chemistry,we construct a conceptual model to elucidate the electrochemical consequence of the inhomogeneous local impedance over the particle *** beyond the implication in battery science,our work highlights a balance between the high-resolution probing the local chemistry and the statistical representativeness,which is particularly vital in the study of the highly complex material systems.

关键词： Ni-rich cathode x-ray nanoprobe redox heterogeneity surface chemistry

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Diagnosis of choroid plexus papilloma: Current perspectives and future directions

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Cancer Pathogenesis and Therapy 2024年第3期2卷 173-179页

作者： Esma'il Akade Fereshteh Aslani Kimia Verdi Mohammad Bahadoram Gholam Abbas Kaydani Department of Medical Virology School of MedicineAhvaz Jundishapur University of Medical SciencesAhvaz ***Iran Department of Laboratory Sciences School of Allied Medical SciencesAhvaz Jundishapur University of Medical SciencesAhvaz ***Iran Department of Physiology School of MedicineAhvaz Jundishapur University of Medical SciencesAhvaz ***Iran Department of Neurology School of MedicineAhvaz Jundishapur University of Medical SciencesAhvaz ***Iran

Choroid plexus papilloma(CPP)is a rare,slow-growing,and typically benign brain tumor that predominantly affects *** is characterized by well-defined circular or lobulated masses in the ventricles,leading to symptoms related to increased intracranial pressure and *** diagnosis relies on a combination of clinical presentation,imaging findings,and histological *** World Health Organization(WHO)classification categorizes choroid plexus tumors into CPP(Grade Ⅰ),atypical CPP(aCPP,Grade Ⅱ),and choroid plexus carcinoma(CPC,Grade Ⅲ).This article reviewed current diagnostics modalities and explored the emergence of new diagnostic methods for *** on molecular markers and genetic alterations associated with CPP is ongoing,and some potential markers have been *** results offered insights into potential therapeutic targets and personalized treatment approaches for *** in radiomics and liquid biopsy hold promise for improving diagnostic accuracy and monitoring treatment outcomes for choroid plexus *** can provide quantitative data from imaging studies,whereas liquid biopsy can analyze tumor-derived genetic material and molecular markers from body fluids,such as cerebrospinal fluid(CSF)and *** rapidly evolving fields of molecular and genetic research and novel diagnostic methods require continuous updates and advancements before their application in clinical *** hope that these advancements will lead to earlier and more precise diagnoses,better treatment options,and improved outcomes in patients with CPP and other brain tumors.

关键词： Cerebral ventricle neoplasms Biomarkers Neuroimaging Translational research Histopathological features

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Accurate Diagnosis of SARS-CoV-2 JN.1 by Sanger Sequencing of Receptor-Binding Domain Is Needed for Clinical Evaluation of Its Immune Evasion

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Journal of Biosciences and Medicines 2024年第4期12卷 69-78页

作者： Sin Hang lee Milford Molecular Diagnostics Laboratory Milford CT USA

Background: Omicron JN.1 has become the dominant SARS-CoV-2 variant in recent months. JN.1 has the highest number of amino acid mutations in its receptor binding domain (RBD) and has acquired a hallmark L455S mutation. The immune evasion capability of JN.1 is a subject of scientific investigation. The US CDC used SGTF of TaqPath COVID-19 Combo Kit RT-qPCR as proxy indicator of JN.1 infections for evaluation of the effectiveness of updated monovalent XBB.1.5 COVID-19 vaccines against JN.1 and recommended that all persons aged ≥ 6 months should receive an updated COVID-19 vaccine dose. Objective: Recommend Sanger sequencing instead of proxy indicator to diagnose JN.1 infections to generate the data based on which guidelines are made to direct vaccination policies. Methods: The RNA in nasopharyngeal swab specimens from patients with clinical respiratory infection was subjected to nested RT-PCR, targeting a 398-base segment of the N-gene and a 445-base segment of the RBD of SARS-CoV-2 for amplification. The nested PCR amplicons were sequenced. The DNA sequences were analyzed for amino acid mutations. Results: The N-gene sequence showed R203K, G204R and Q229K, the 3 mutations associated with Omicron BA.2.86 (+JN.1). The RBD sequence showed 24 of the 26 known amino acid mutations, including the hallmark L455S mutation for JN.1 and the V483del for BA.2.86 lineage. Conclusions: Sanger sequencing of a 445-base segment of the SARS-CoV-2 RBD is useful for accurate determination of emerging variants. The CDC may consider using Sanger sequencing of the RBD to diagnose JN.1 infections for statistical analysis in making vaccination policies.

关键词： Omicron JN.1 SARS-CoV-2 Sanger Sequencing RBD L455S Mutation Immune Evasion Vaccination Policies CDC

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