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载黄芪甲苷的核壳结构纳米纤维创面敷料的制备及性能

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功能高分子学报 2024年第4期37卷 338-346页

作者：王红伟王立红刘泽梅罗永明康致超车鑫贵州中医药大学药学院贵州550025

采用静电纺丝技术制备同轴黄芪甲苷(AS)/聚乙烯吡咯烷酮(PVP)/聚乳酸(PLA)纳米纤维功能敷料。对纳米纤维的微观形貌、原料与辅料间化学相互作用、润湿性、水蒸气透过率、抗氧化、抗菌及促糖尿病创面愈合等性能进行研究。结果表明,AS/PVP... 详细信息

采用静电纺丝技术制备同轴黄芪甲苷(AS)/聚乙烯吡咯烷酮(PVP)/聚乳酸(PLA)纳米纤维功能敷料。对纳米纤维的微观形貌、原料与辅料间化学相互作用、润湿性、水蒸气透过率、抗氧化、抗菌及促糖尿病创面愈合等性能进行研究。结果表明,AS/PVP/PLA纳米纤维有明显的核壳结构,纤维直径为(480±240)nm、接触角为(88.73±1.07)°、水蒸气透过率为(1660.42±80.61)g/(m^(2)·d)、自由基清除率为47%,对大肠杆菌、金黄色葡萄球菌均有明显的抑菌作用。促糖尿病创面愈合结果表明,第14 d时糖尿病大鼠的创面愈合率达到(99.75±0.05)%。

关键词：静电纺丝聚乙烯吡咯烷酮聚乳酸黄芪甲苷创面敷料

The diel vertical migration of the sound-scattering layer in the Yellow Sea Bottom Cold Water of the southeastern Yellow Sea: focus on its relationship with a temperature structure

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Acta Oceanologica Sinica 2013年第9期32卷 44-49页

作者： LEE Hyungbeen CHO Sungho KIM Woongseo kang Donhyug Maritime Security Research Center Korea Institute of Ocean Science&Technology Deep-sea and Seabed Resources Research Division Korea Institute of Ocean Science&Technology

Using the hydroacoustic method with a 200 kHz scientific echo sounding system, the diel vertical migration （DVM） of the sound-scatteringlayer （SSL） in the Yellow Sea Bottom Cold Water （YSBCW） of the southeastern Yellow Sea was studied in April （spring） and August （summer） of 2010 and 2011. For each survey, 13-27 hours of acoustic data were continuously collected at a stationary station. The acoustic volume scattering strength （Sv） data were analyzed with temperature profile data. In the spring of both 2010 and 2011, the SSL clearly showed the vertical migration throughout the entire water column, moving from the surface layer at night to near the bottom during the day. Conductivity, temperature, and depth data indicated that the entire water column was well mixed with low temperature of about 8℃. However, the SSL showed different patterns in the summers of 2010 and 2011. In the summer of 2010 （≈28℃ at the surface）, the SSL migrated to near the bottom during the day, but there were two SSLs above and below the thermocline at depth of 10-30 m at night. In the summer of 2011 （≈20℃ at the surface）, the SSL extended throughout the entire water column at night, possibly owing to an abrupt change in sea weather conditions caused by the passage of a Typhoon Muifa over the study area. It was cancluded that the DVM patterns in summer in the YSBCW area may be greatly influenced by a strengthened or weakened thermocline.

关键词： diel vertical migration sound-scattering layer temperature structure typhoon Yellow Sea Bot- tom Cold Water

Evaluating the Risk of Disclosure and Utility in a Synthetic Dataset

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Computers, Materials & Continua 2021年第7期68卷 761-787页

作者： kang-Cheng Chen Chia-Mu Yu Tooska Dargahi Industrial Technology Research Institute Hsinchu310Taiwan National Chiao Tung University Hsinchu320Taiwan University of Salford ManchesterM54WTUnited Kingdom

The advancement of information technology has improved the delivery of nancial services by the introduction of Financial Technology(FinTech).To enhance their customer satisfaction,Fintech companies leverage articial intelligence(AI)to collect ne-grained data about individuals,which enables them to provide more intelligent and customized ***,although visions thereof promise to make customers’lives easier,they also raise major security and privacy concerns for their *** privacy(DP)is a common privacy-preserving data publishing technique that is proved to ensure a high level of privacy ***,an important concern arises from the trade-off between the data utility the risk of data disclosure(RoD),which has not been well *** this paper,to address this challenge,we propose data-dependent approaches for evaluating whether the sufcient privacy is guaranteed in differentially private data *** the same time,by taking into account the utility of the differentially private synthetic dataset,we present a data-dependent algorithm that,through a curve tting technique,measures the error of the statistical result imposed to the original dataset due to the injection of random ***,we also propose a method that ensures a proper privacy budget,i.e.,will be chosen so as to maintain the trade-off between the privacy and *** comprehensive experimental analysis proves both the efciency and estimation accuracy of the proposed algorithms.

关键词： Differential privacy risk of disclosure privacy utility

Statistical studies of optically dark gamma-ray bursts in the Swift era

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Research in Astronomy and Astrophysics 2009年第10期9卷 1103-1118页

作者： Wei-kang Zheng Jin-Song Deng Jing Wang National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China Graduate University of Chinese Academy of Science Beijing 100049 China

We compare the properties of optically dark GRBs, defined by the optical-to-X- ray spectral indexβox 〈 0.5, and normal ones discovered by the Swift satellite before the year 2008 in a statistical way, using data collected from the literature and online databases. Our sample includes 200 long bursts, 19 short bursts, and 10 with measured high redshifts （z ≥ 4）. The ratio of dark bursts is found to be -10% - 20%, and is similar among long bursts, short ones, and the high-z sub-sample. The result for long bursts is consistent with both the pre-Swift sample and studies by other authors on smaller Swift samples. The existence of dark short GRBs is pointed out for the first time. The X-ray derived hydrogen column densities of dark GRBs clearly prefer large values compared with those of normal bursts. This supports the dust extinction scenario as the main cause of dark GRBs. Other possibilities like very high redshifts and non-standard emission mechanisms are less likely, although not fully excluded.

关键词： gamma rays bursts -- gamma rays observations

A biofilter model for simultaneous simulation of toluene removal and bed pressure drop under varied inlet Ioadings

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Frontiers of Environmental Science & Engineering 2015年第3期9卷 554-562页

作者： Jinying XI Insun kang Hongying HU Xian ZHANG Environmental Simulation and Pollution Control State Key Joint Laboratory School of Environment Tsinghua University Beijing 100084 China Graduate School at Shenzhen Tsinghua University Shenzhen 518055 China

In this study, a biofiltration model including the effect of biomass accumulation and inert biomass growth is developed to simultaneously predict the Volatile Organic Compounds （VOCs） removal and filter bed pressure drop tmder varied inlet loadings. A laboratoryscale experimental biofilter for gaseous toluene removal was set up and operated for 100 days with inlet toluene concentration ranging from 250 to 2500 mg· m^-2 According to sensitivity analysis based on the model, the VOCs removal efficiency of the biofilter is more sensitive to Henry＇s constant, the specific surface area of the filter bed and the thickness of water layer, while the filter bed pressure drop is more sensitive to biomass yield coefficient and original void fraction. The calculated toluene removal efficiency and bed pressure drop satisfactorily fit the experimental data under varied inlet toluene loadings, which indicates the model in this study can be used to predict VOCs removal and bed pressure drop simultaneously. Based on the model, the effect of mass-transfer parameters on VOCs removal and the stable-run time of a biofilter are analyzed. The results demonstrate that the model can function as a good tool to evaluate the effect of biomass accumulation and optimize the design and operation of biofilters.

关键词： Volatile Organic Compounds (VOCs) biofil- ters modelling biomass accumulation pressure drop

Face stability analysis of large shield-driven tunnel in rock-soil interface composite formations

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Underground Space 2022年第6期7卷 1021-1035页

作者： Xiaobin Ding kang Li Yuxuan Xie Shuzhuo Liu School of Civil Engineering and Transportation South China University of TechnologyGuangzhou 510641China Guangdong Provincial Key Laboratory of Modern Civil Engineering Technology South China Institute of Geotechnical EngineeringGuangzhou 510650China

A new 3D log-spiral model(LS-M model)is proposed to determine the minimal support pressure on the tunnel face of a large shielddriven tunnel in rock-soil interface(RSI)composite *** the proposed LS-M model,we define the RSI angle ω and use a new approach to calculate the equivalent tunnel face area,which provides a collapse zone with more realistic geometry than the traditional wedge *** it has acceptable accuracy with simpler implementation than limit equilibrium *** with previous studies and 3D numerical analysis,it indicates that:(i)the LS-M results agree well with others in full-soil formations on the variation patterns of minimum support pressure and stability coefficients N_(c) and N_(γ);(ii)the critical RSI angle ω_(cr),which is predominantly influenced by soil cohesion,increases with the soil property values;(iii)the limit support pressure starts to increase with ω only when ω>ω_(cr);(iv)the peak support pressure occurs at lower C/D with a lower ω;(v)ω can only affect stability coefficients N_(c) and N_(γ) when ω and the friction angle are relatively small,while N_(s) is substantially influenced by RSI angle ω.

关键词： Tunnel Stability Limit support pressure RSI composite formations 3D failure mechanism

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人工智能、产品创新与制造业适应性转型

北京交通大学学报（社会科学版） 2024年第1期23卷 84-95页

作者：谢康卢鹏盛君叶肖静华孙浩博中山大学管理学院广东广州510275

人工智能(AI)对产品开发、运营和营销等企业价值链的影响正在改变制造业转型升级的机制与路径。围绕AI如何通过影响产品创新推动制造业转型升级,本文依托相关研究成果提炼AI区别于其他数字技术的核心创新特征,剖析AI对产品创新的影响机... 详细信息

人工智能(AI)对产品开发、运营和营销等企业价值链的影响正在改变制造业转型升级的机制与路径。围绕AI如何通过影响产品创新推动制造业转型升级,本文依托相关研究成果提炼AI区别于其他数字技术的核心创新特征,剖析AI对产品创新的影响机制,并通过AI影响个体、企业、产业的跨层次分析框架,从产品创新视角提出AI影响制造业转型升级的适应性变革概念模型,探讨AI通过产品创新影响制造业适应性转型的机制与路径,形成三个主要结论:(1)新社会主体、生成性、知识积累方式突变性构成AI区别于其他数字技术的三个核心创新特征;(2)AI作为新社会主体角色介入产品企划、结构工艺等开发环节,改变或增强了人类智能的产品开发思维,拓展了产品开发的知识边界;(3)AI增强产品创新与运营过程、市场营销和销售的全价值链即时互动和调整,构建起平衡制造敏捷性与用户敏捷性冲突的自适应调节机制,推动制造业通过产业快速自适应调节涌现出自适应间断平衡的转型路径。

关键词：人工智能产品创新新社会主体制造业转型升级适应性变革

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Induced pluripotent stem cells(iPSCs)——a new era of reprogramming

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Journal of Genetics and Genomics 2010年第7期37卷 415-421页

作者： Lan kang Zhaohui Kou Yu Zhang Shaorong Gao National Institute of Biological Sciences NIBS Beijing 102206 China

Embryonic stem cells （ESCs） derived from the early embryos possess two important characteristics：self-renewal and pluripotency,which make ESCs ideal seed cells that could be potentially utilized for curing a number of degenerative and genetic diseases ***,ethical concerns and immune rejection after cell transplantation limited the clinical application of ***,the recent advances in induced pluripotent stem cell （iPSC） research have clearly shown that differentiated somatic cells from various species could be reprogrammed into pluripotent state by ectopically expressing a combination of several transcription factors,which are highly enriched in *** ground-breaking achievement could circumvent most of the limitations that ESCs ***,it remains challenging if the iPS cell lines,especially the human iPSCs lines,available are fully ***,it is prerequisite to establish a molecular standard to distinguish the better quality iPSCs from the inferior ones.

关键词： induced pluripotent stem cells (iPSCs) reprogramming molecular events

伯方煤矿采空区“三带”分布特征及在高位长钻孔抽采中的应用

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煤炭科技 2024年第2期45卷 105-110页

作者：郭泽明贺寿彭安康山西兰花科技创业股份有限公司伯方煤矿分公司山西高平048400 河南理工大学安全科学与工程学院河南焦作454003

为提高伯方煤矿3305工作面采空区瓦斯抽采效果,通过数值模拟分析了工作面不同推进距离时覆岩垮落与裂隙演化规律,进而确定了3305工作面采空区“三带”高度;最后分析定向高位长钻孔布置层位选择,并在3305工作面开展了定向高位长钻孔抽采... 详细信息

为提高伯方煤矿3305工作面采空区瓦斯抽采效果,通过数值模拟分析了工作面不同推进距离时覆岩垮落与裂隙演化规律,进而确定了3305工作面采空区“三带”高度;最后分析定向高位长钻孔布置层位选择,并在3305工作面开展了定向高位长钻孔抽采效果考察。结果表明,3305工作面上覆岩层垮落带的最大高度为17.5 m,而裂隙带的最大高度则为56 m。定向高位长钻孔的瓦斯抽采量在2.06~11.09 m^(3)/min,瓦斯抽采浓度保持在一个较高水平,平均浓度达到44%,表明定向高位长钻孔终孔位置位于裂隙带的中下部能够高效的抽采采空区瓦斯。

关键词：瓦斯抽采长钻孔 “三带” 采空区裂隙