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China Today 1999年第10期48卷 27-29页

作者： by staff reporter xue lisheng

Photocatalytic degradation of methylene blue over MIL-100(Fe)/GO composites: a performance and kinetic study

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International Journal of Coal Science & Technology 2024年第3期11卷 208-222页

作者： Yuxue Wei Zhiyuan Fu Yingzi Meng Chun Li Fu Yin xue Wang Chenghua Zhang lisheng Guo Song Sun School of Chemistry and Chemical Engineering Anhui UniversityHefei230601AnhuiChina Anhui Tanxin Technology Co. LtdHuaibei235141AnhuiChina

Adsorption coupled with photocatalytic degradation is proposed to fulfill the removal and thorough elimination of organic ***,we report a facile hydrothermal synthesis of MIL-100(Fe)/GO *** adsorption and photocatalytic degradation process of methylene blue(MB)on MIL‐100(Fe)/GO composites were systematically studied from performance and kinetic perspectives.A possible adsorption‐photocatalytic degradation mechanism is *** optimized 1M8G composite achieves 95%MB removal(60.8 mg/g)in 210 min and displays well recyclability over ten *** obtained MB adsorption and degradation results are well fitted onto Langmuir isotherm and pseudo‐second order kinetic *** study shed light on the design of MOFs based composites for water treatment.

关键词： Graphene oxide Metal organic frameworks Methylene blue Adsorption Photocatalytic degradation

MiRNA-145-5p inhibits gastric cancer progression via the serpin family E member 1-extracellular signal-regulated kinase-1/2 axis

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2123-2140页

作者： Hong-Xia Bai xue-Mei Qiu Chun-Hong Xu Jian-Qiang Guo Department of Gastroenterology The Second Hospital of Shandong UniversityJinan 250000Shandong ProvinceChina Department of Gastroenterology Liaocheng People’s HospitalLiaocheng 252000Shandong ProvinceChina Department of Reproductive Center Zaozhuang Maternal and Child Health Care HospitalZaozhuang 277000Shandong ProvinceChina

BACKGROUND MicroRNAs(miRNAs)regulate gene expression and play a critical role in cancer ***,there is still a limited understanding of the function and regulatory mechanism of miRNAs in gastric cancer(GC).AIM To investigate the role and molecular mechanism of miRNA-145-5p(miR145-5p)in the progression of *** Real-time polymerase chain reaction(RT-PCR)was used to detect miRNA expression in human GC tissues and *** ability of cancer cells to migrate and invade was assessed using wound-healing and transwell assays,*** proliferation was measured using cell counting kit-8 and colony formation assays,and apoptosis was evaluated using flow *** of the epithelial-mesenchymal transition(EMT)-associated protein was determined by Western *** of miR-145-5p were predicated using bioinformatics analysis and verified using a dual-luciferase reporter *** family E member 1(SERPINE1)expression in GC tissues and cells was evaluated using RT-PCR and immunohistochemical *** correlation between SERPINE1 expression and overall patient survival was determined using Kaplan-Meier plot *** association between SERPINE1 and GC progression was also tested.A rescue experiment of SERPINE1 overexpression was conducted to verify the relationship between this protein and *** mechanism by which miR-145-5p influences GC progression was further explored by assessing tumor formation in nude *** GC tissues and cells had reduced miR-145-5p expression and SERPINE1 was identified as a direct target of this *** of miR-145-5p was associated with decreased GC cell proliferation,invasion,migration,and EMT,and these effects were reversed by forcing SERPINE1 ***-Meier plot analysis revealed that patients with higher SERPINE1 expression had a shorter survival rate than those with lower SERPINE1 *** mouse tumorigenesis experiments confirmed that miR-145-5p target

关键词： Gastric cancer MicroRNA-145-5p Serpin family E member 1 Epithelial-mesenchymal transition Proliferation Extracellular signal-regulated kinase-1/2

Palmitic acid reduces the methylation of the FOXO1 promoter to suppress the development of diffuse large B-cell lymphoma via modulating the miR-429/DNMT3A axis

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Chinese Journal of Natural Medicines 2024年第6期22卷 554-567页

作者： LI Weiming GAO Ming xue Weili LI Xiaoli CHANG Yu ZHANG Kaixin WEN Chenyu ZHANG Mingzhi Department of Oncology Henan University of Traditional Chinese MedicineZhengzhou 450000China Department of Oncology The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450000China

Diffuse large B-cell lymphoma(DLBCL)is characterized by significant treatment *** acid(PA)has shown promising antitumor *** study aims to elucidate the molecular mechanisms by which PA influences DLBCL *** quantified the expression levels of microRNAs(miRNAs),Forkhead box protein O1(FOXO1),and DNA methyltransferase 3A(DNMT3A)in both untreated and PA-treated DLBCL tumors and cell *** were made of cell viability,apoptosis,and autophagy-related protein expression following PA *** analyses among miR-429,DNMT3A,and FOXO1 were conducted using luciferase reporter assays and methylation-specific(MSP)Polymerase chain reaction(PCR).After transfecting the miR-429 inhibitor,negative control(NC)inhibitor,shRNA against DNMT3A(sh-DNMT3A),shRNA negative control(sh-NC),over-expression vector for DNMT3A(oe-DNMT3A),or overexpression negative control(oe-NC),we evaluated the effects of miR-429 and DNMT3A on cell viability,mortality,and autophagy-related protein expression in PA-treated DLBCL cell *** efficacy of PA was also tested in vivo using DLBCL tumor-bearing mouse ***-429 and FOXO1 expression levels were downregulated,whereas DNMT3A was upregulated in DLBCL compared to the control *** treatment was associated with enhanced autophagy,mediated by the upregulation of miR-429 and downregulation of *** luciferase reporter assay and MSP confirmed that miR-429 directly inhibits DNMT3A,thereby reducing FOXO1 *** experiments demonstrated that PA promotes autophagy and inhibits DLBCL progression by upregulating miR-429 and modulating the DNMT3A/FOXO1 *** vivo PA signific-antly reduced the growth of xenografted tumors through its regulatory impact on the miR-429/DNMT3A/FOXO1 *** acid may modulate autophagy and inhibit DLBCL progression by targeting the miR-429/DNMT3A/FOXO1 signaling pathway,suggesting a novel therapeutic target for DLBCL management.

关键词： Palmitic acid Diffuse large B-cell lymphoma MiR-429 DNMT3A FOXO1 Autophagy

An optimized high-throughput SARS-CoV-2 dual reporter trans-complementation system for antiviral screening in vitro and in vivo

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Virologica Sinica 2024年第3期39卷 447-458页

作者： Yingjian Li xue Tan Jikai Deng xuemei Liu Qianyun Liu Zhen Zhang Xiaoya Huang Chao Shen Ke Xu Li Zhou Yu Chen State Key Laboratory of Virology RNA InstituteCollege of Life Sciences and Frontier Science Center for Immunology and MetabolismWuhan UniversityWuhan430072China Institute for Vaccine Research at Animal Bio-safety Level III Laboratory Wuhan University School of MedicineWuhan430071China

The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is still epidemic around the *** manipulation of SARS-CoV-2 is restricted to biosafety level 3 laboratories(BSL-3).In this study,we developed a SARS-CoV-2ΔN-GFP-HiBiT replicon delivery particles(RDPs)encoding a dual reporter gene,GFP-HiBiT,capable of producing both GFP signal and luciferase *** optimal selection of the reporter gene,GFP-HiBiT demonstrated superior stability and convenience for antiviral ***,we established a RDP infection mouse model by delivering the N gene into K18-hACE2 KI mouse through *** mouse model supports RDP replication and can be utilized for in vivo antiviral *** summary,the RDP system serves as a valuable tool for efficient antiviral screening and studying the gene function of ***,this system can be manipulated in BSL-2 laboratories,decreasing the threshold of experimental requirements.

关键词： SARS-CoV-2 RDP Antiviral evaluation Mouse model BSL-2

Drop casting based superhydrophobic and electrically conductive coating for high performance strain sensing

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Nano Materials Science 2022年第2期4卷 178-184页

作者： Ling Wang lisheng Wu Yuqing Wang Junchen Luo Huaiguo xue Jiefeng Gao School of Chemistry and Chemical Engineering Yangzhou UniversityYangzhouJiangsu225002China

Conductive polymer composites(CPCs)strain sensors exhibit promising applications in flexible electronics,people’s health monitoring,*** remains a big challenge to develop a simple and cost-effective method to prepare CPCs with high conductivity,corrosion resistance,strong interfacial adhesion and high ***,we propose a facile“drop-casting and fluorination”strategy to fabricate superhydrophobic and highly electrically conductive coating by Ag precursor adsorption onto a commercially available elastic tape,subsequent chemical reduction and final *** Ag nanoparticles could not only construct the electrically conductive network but also greatly enhance the surface *** contact angle and electrical conductivity of the coating can reach as high as 156°and 126 S/cm,*** used for strain sensing,the superhydrophobic and conductive coating shows a high gauger factor(up to 7631 with the strain from 44%to 50%)and outstanding *** strain sensor could monitor different body joint motions with the stable and reliable sensing signals even after long time treatment in a corrosive solution.

关键词： Drop-casting Contact angle Ag nanoparticles Strain sensor

NOMA-Aided Generalized Pre-Coded Quadrature Spatial Modulation for Downlink Communication Systems

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China Communications 2020年第11期17卷 120-130页

作者： Jun Li Jia Hou lisheng Fan Yier Yan xue-Qin Jiang Han Hai Research Center of Intelligent Communication Engineering School of Electronics and Communication EngineeringGuangzhou UniversityGuangzhou 510006China School of Electronic and Information Engineering Soochow UniversitySuzhou 215006China School of Computer Science Guangzhou UniversityGuangzhou 510006China School of Information Science and Technology Donghua UniversityShanghai 201620China

Generalised pre-coding quadrature spatial modulation(GPQSM)is recently proposed to increase the spectral efficiency(SE)of GPSM,which extends the transmitted symbols into in-phase/quadrature *** this paper,a novel scheme named non-orthogonal multiple access(NOMA)-aided GPQSM(NOMA-GPQSM),which incorporates the GPQSM scheme into the multi-user communication networks with assist of NOMA,is proposed to further improve the SE and system *** NOMA-GPQSM,one base station(BS)is set to serve K users,where user 1 is closest to the BS,and user K is farthest from the *** addition,a low-complexity detection method is proposed to reduce the high detection complexity of the maximum-likelihood(ML)detection in successive interference cancellation(SIC)method for all users by *** theoretical analysis of the BER performance for all users is also *** results show that near users achieve relatively good performance,and far users achieve acceptable performance by adjusting power factors for all users in NOMA-GPQSM.

关键词： spatial modulation index modulation non-orthogonal multiple access bit error rate pre-coding

Further Reform and Opening-up——A Must for Integration into the World Economy An Interview with xue Rongjiu, Vice-Chairman of the China Society for World Trade Organization Studies

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China Today 2011年第12期60卷 26-29页

作者： staff reporter LU RUCAI

THE year 2011 marks the 10th anniversary of China’s accession to the World Trade Organization (WTO). Benefiting from the rules of the WTO, China’s foreign trade and economic strength have fueled its rapid development during the past decade. The rules propelled China to not only undertake further reform and opening-up, but also improve its market economy system. China Today (CT) were granted an exclusive interview with

关键词：世界贸易组织世界经济中国 OPE 副会长改革集成世贸组织

Century Wedding Ceremony

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China Today 2000年第1期49卷 26-29页

作者： xue lisheng

Details the special millennium wedding ceremony in China held on January 1, 2000. How the ceremony started; Participants of the ceremony.

关键词： MARRIAGE service WEDDINGS

Shanghai　Through　the　Eyes　of　foreigners

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China Today 1998年第1期47卷 19-21页

作者： lisheng, xue

ＳｈａｎｇｈａｉＴｈｒｏｕｇｈｔｈｅＥｙｅｓｏｆｆｏｒｅｉｇｎｅｒｓＳｈａｎｇｈａｉｈａｓａｔｔｒａｃｔｅｄｍｕｃｈｉｎｔｅｒｎａｔｉｏｎａｌａｔｔｅｎｔｉｏｎｗｉｔｈｉｔｓｄｅｖｅｌｏｐｍｅｎｔｔｈｉｓｄｅｃａｄｅ... 详细信息

ＳｈａｎｇｈａｉＴｈｒｏｕｇｈｔｈｅＥｙｅｓｏｆｆｏｒｅｉｇｎｅｒｓＳｈａｎｇｈａｉｈａｓａｔｔｒａｃｔｅｄｍｕｃｈｉｎｔｅｒｎａｔｉｏｎａｌａｔｔｅｎｔｉｏｎｗｉｔｈｉｔｓｄｅｖｅｌｏｐｍｅｎｔｔｈｉｓｄｅｃａｄｅ．ＡｆｔｅｒＤｅｎｇＸｉａｏｐｉｎ...

关键词： foreigners the Through Shanghai