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Nuclear liquid-gas phase transition within a Brueckner-Hartree-Fock approach

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Chinese Physics C 2022年第11期46卷 231-237页

作者：张晶刘宏铭李增花 g.F.burgio H.-J.Schulze Institute of Modern Physics Key Laboratory of Nuclear Physics and Ion-beam Application(MOE)Fudan UniversityShanghai 200433China INFN Sezione di Catania Dipartimento di Fisica e AstronomiaUniversitàdi CataniaVia S.Sofia 64I-95123 CataniaItaly

The critical parameters of the liquid-gas phase transition of symmetric nuclear matter are computed using the Brueckner-Hartree-Fock method at finite temperature by employing different realistic nucleon-nucleon *** effects on single-particle potentials,defect functions,and three-body forces are discussed in *** obtained from the full procedure and frozen-correlations approximation are *** find critical temperatures of approximately 14 to 19 MeV and critical densities in the range of 0.05 to 0.08fm^(-3),depending on the interactions employed.

关键词： nuclear liquid-gas phase transition Brueckner-Hartree-Fock approach symmetric nuclear matter

Harnessing CRISPR-Cas system diversity for gene editing technologies

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The Journal of Biomedical Research 2021年第2期35卷 91-106页

作者： Alexander McKay gaetan burgio Department of Immunology and Infectious Diseases John Curtin School of Medical ResearchAustralian National UniversityCanberraACT 2601Australia

The discovery and utilization of RNA-guided surveillance complexes,such as CRISPR-Cas9,for sequencespecific DNA or RNA cleavage,has revolutionised the process of gene modification or *** optimise the use of this technology,an exploratory race has ensued to discover or develop new RNA-guided endonucleases with the most flexible sequence targeting requirements,coupled with high cleavage efficacy and *** we review the constraints of existing gene editing and assess the merits of exploiting the diversity of CRISPR-Cas effectors as a methodology for surmounting these limitations.

关键词： CRISPR-Cas systems gene editing biological evolution DNA repair classification DNA transposable elements

Modelling the interaction of the Astro Bio Cube Sat with the Van Allen's Belt radiative field using Monte Carlo transport codes

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Radiation Detection Technology and Methods 2022年第2期6卷 262-279页

作者： N.burgio L.Cretara M.Corcione M.Frullini L.lannascoli A.Nascetti A.Santagata g.Palmerini A.Quintino J.R.Brucato A.Meneghin D.Paglialunga ENEA FSN-FISS-RNRC.R.CasacciaRomeItaly DIAEE Sapienza UniversitàDi RomaVia Eudossiana 1800184 RomeItaly School of Aerospace Engineering Sapienza University of RomeVia Salaria 85100138 RomeItaly INAF-Astrophysical Observatory of Arcetri L.go E.Fermi 550125 FlorenceItaly

Purpose The AstroBio Cube Satellite(ABCS)will deploy within the inner Van Allen belt on the Vega C Maiden Flight launch opportunity of the European Space *** this altitude,ABCS will experience radiation doses orders of magnitude greater than in low earth orbit,where CubeSats usually *** paper aims to estimate the irradiation effect on the ABCS payload in the orbital condition,their possible mitigation designing shielding solutions and performs a preliminary representativity simulation study on the ABCS irradiation with fission neutron at the TAPIRO(TAratura Pila Rapida Potenza 0)nuclear research reactor facility at *** We quantify the contributions of geomagnetically trapped particles(electron and proton),galactic Cosmic Rays(gCR ions),Solar energetic particle within the ABCS orbit using the ESA's SPace ENVironment information ***(Fluktuierende Kaskade-Fluctuating Cascade)code models the ABCS interaction with the orbital *** We found a shielding solution of the weight of 300 g constituted by subsequent layers of tungsten,resins,and aluminium that decreases on average the 20%overall dose rate relative to the shielding offered by the only satellite's ***,simulations of neutron irradiation of the whole ABCS structure within the TAPIRO's thermal column cavity show that a relatively short irradiation time is requested to reach the same level of 1 MeV neutron Silicon equivalent damage of the orbital *** The finding deserves the planning of a future experimental approach to confirm the TAPIRO's performance and establish an irradiation protocol for testing aerospatial electronic components.

关键词： galactic cosmic rays and solar energetic particles Spacecraft shielding Dosimetry Monte Carlo methods MCNP and FLUKA

Three-dimensional imaging reconstruction of the kidney’s anatomy for a tailored minimally invasive partial nephrectomy:A pilot study

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Asian Journal of Urology 2022年第3期9卷 263-271页

作者： Daniele Amparore Angela Pecoraro Federico Piramide Paolo Verri Enrico Checcucci Sabrina De Cillis Alberto Piana Mariano burgio Michele Di Dio Matteo Manfredi Cristian Fiori Francesco Porpiglia Department of Urology San Luigi Gonzaga HospitalUniversity of TurinOrbassanoTurinItaly European Association of Urology(EAU)Young Academic Urologists(YAU)Renal Cancer Working group ArnhemNetherlands European Association of Urology(EAU)Young Academic Urologists(YAU)Uro-technology and SoMe Working group ArnhemNetherlands Division of Urology Department of SurgerySS Annunziata HospitalCosenzaItaly

Objective:The aim of the study was to evaluate three-dimensional virtual models(3DVMs)usefulness in the intraoperative assistance of minimally-invasive partial nephrectomy in highly complex renal ***:At our institution cT1-2N0M0 all renal masses with Preoperative Aspects and Dimensions Used for an Anatomical classification score≥10 treated with minimally-invasive partial nephrectomy were considered for the present *** inclusion a baseline contrast-enhanced computed tomography in order to obtain 3DVMs,the baseline and postoperative serum creatinine as well as estimated glomerular filtration rate values were *** patients,in which 3DVMs were used to assist the surgeon in the planning and intraoperative guidance,were then compared with a control group of patients who underwent minimally-invasive partial nephrectomy with the same renal function assessments,but without *** logistic regression models were used to predict the margin,ischemia,and complication score ***:Overall,79 patients met the inclusion criteria and were compared with 143 complex renal masses without 3DVM *** 3DVM group showed better postoperative outcomes in terms of baseline-weighted differential estimated glomerular filtration rate(-17.7%vs.-22.2%,p=0.03),postoperative complications(16.5%vs.23.1%,p=0.03),and major complications(Clavien Dindo>III,2.5%vs.5.6%,p=0.03).At multivariable logistic regression 3DVM assistance independently predicted higher rates of successful partial nephrectomy(odds ratio:1.42,p=0.03).Conclusion:3DVMs represent a useful tool to plan a tailored surgical approach in case of surgically complex *** can be used in different ways,matching the surgeon's needs from the planning phase to the demolitive and reconstructive phase,leading towards maximum safety and efficacy outcomes.

关键词： Three-dimensional Kidney cancer Renal cell carcinoma Robotic Laparoscopic Nephron-sparing surgery Complex renal mass

非酒精性脂肪肝病人肝细胞癌与骨骼肌脂肪浸润的异质性模式相关

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国际医学放射学杂志 2024年第3期 372-372页

作者： M.Nachit M.Dioguardi burgio A.Abyzov P.garteiser V.Paradis V.Vilgrain 余翔玲

摘要目的评估非酒精性脂肪肝（NAFLD）病人骨骼肌脂肪浸润（肌肉脂肪变性）与肝细胞肝癌（HCC）之间的关系。方法纳入72例经组织学证实的NAFLD病人并进行横断面

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Anejaculation in a patient with Charcot-Marie-Tooth

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Asian Journal of Andrology 2018年第5期20卷 529-530页

作者： Rossella Cannarella giovanni burgio Sandro La Vignera Enzo S Vicari Aldo E Calogero Department of Clinical and Experimental Medicine University of Catania Catania95123 Italy

Dear Editor,The occurrence of delayed ejaculation or ane）aculation has been previously suggested in patients with Charcot-Marie-Tooth （CMT） syndrome.1 Despite this, such disorder is rarely investigated and may be underestimated in patients with this disease. We report the case of a 20-year-old men with CMT 1B due to the presence of a punctiform mutation in the exon 2 of the myelin protein zero （MPZ） gene （ 1 q23.3）（Ser78Leu）, complaining for life-long anejaculation. He inherited this mutation from the mother and it has also been detected in his grandmother. No other components of his family were positive at the genetic testing.

关键词： DISEASE

Evaluation of the potential exposure of butterflies to genetically modified maize pollen in protected areas in Italy

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Insect Science 2018年第4期25卷 549-561页

作者： Salvatore Arpaia Ferdinando Baldacchino Sara Bosi giovanni burgio Simona Errico Rosaria Alessandra Magarelli Antonio Masetti Salvatore Santorsola ENEA-Italian National Agency for New Technologies Energy and Sustainable Economic Development Research Centre Trisaia Rotondella (MT) Italy Dipartimento di Scienze Agrarie Alma Mater Studiorum Universita di Bologna Bologna Italy

Environmental impacts of genetically modified crops are mandatorily assessed during their premarket phase. One of the areas of concern is the possible impact on nontar- get organisms. Crops expressing Cry toxins might affect Lepidoptera larvae living outside cultivated fields, through pollen deposition on wild plants, which constitute their food source. While pollen toxicity varies among different events, possible exposure ofnontarget species depends on the agro-environmental conditions. This study was conducted in two protected areas in Italy, characterized by different climatic conditions, where many Lepi- doptera species thrive in proximity to maize cultivations. To estimate the possible exposure in absence of the actual stressor （e.g., Cryl-expressing maize plants）, we conducted a two-year field survey of butterflies and weeds. Indicator species were selected--Aglais （Inachis） io in the Northern site and Vanessa cardui in the Southern site--and their phe- nology was investigated. Pollen dispersal from maize fields was measured by collection in Petri dishes. Duration and frequency of exposure was defined by the overlap between pollen emission and presence of larvae on host plants. Different risk scenarios are expected in the two regions： highest exposure is foreseen forA. io in the Northern site, while minimal exposure is estimated for V. cardui in the Southern site. In the latter case, locally grown maize cultivars flower in mid-summer in coincidence with an aestivation period for several butterfly species due to hot and dry conditions. Moreover, host plants of V. cardui are at the end of their life cycle thus limiting food availability.

关键词： environmental risk assessment exposure assessment genetically modified plants Lepidoptera nontarget organisms receiving environment

Completely obstructed colorectal anastomosis: A new non-electrosurgical endoscopic approach before balloon dilatation

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World Journal of gastroenterology 2010年第37期16卷 4751-4754页

作者： gabriele Curcio Marco Spada Fabrizio di Francesco Ilaria Tarantino Luca Barresi gaetano burgio Mario Traina Department of gastroenterology IsMeTT UPMC

Benign stricture is a relatively common complication of colorectal anastomosis after low anterior resection. On occasion, the anastomosis may close completely. A variety of endoscopic techniques have been described, but there is a lack of data from controlled prospective trials as to the optimal approach. Through-the-scope balloon dilatation is well known and easy to perform. Some case reports describe different endoscopic approaches, including endoscopic electrocision with a papillotomy knife or hook knife. We report a case of a colorectal anastomosis web occlusion, treated without electrocision. gastrografin enema and sigmoidoscopy showed complete obstruction at the anastomotic site due to the presence of an anastomotic occlusive web. In order to avoid thermal injuries, we decided to use a suprapapillary biliary puncture catheter. The Artifon catheter was inserted into the center of the circular staple line at the level of the anastomosis, and fluoroscopic identification of the proximal bowel was obtained with dye injection. A 0.025-inch guidewire was then passed through the catheter into the colon and progressive pneumatic dilatation was performed. The successful destruction of the occlusive web facilitated passage of the colonoscope, allowing evaluation of the entire colon and stoma closure after three months of follow-up. The patient tolerated the procedure well, with no complications. This report highlights an alternative non-electrosurgical approach that uses a new device that proved to be safe and useful.

关键词： Anastomosis Dilation Balloon Obstructed Artifon

Predation pressure in maize across Europe and in Argentina: an intercontinental comparison

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Insect Science 2019年第3期26卷 545-554页

作者： Marco Ferrante gabor L. Lovei Serena Magagnoli Lenka Minarcikova Elena Larisa Tomescu giovanni burgio Ludovit Cagan Mihael Cristin Ichim Department of Agroecology Aarhus University Flakkebjerg Research Centre Forgssvej 1 DK4200 Slagelse Denmark Dipartimento di Scienze Agrarie Area Entomologia Universita di Bologna Bologna Italy Department of Plant Protection Faculty of Agrobiology and Food Resources Slovak Agricultural University Tr. A. Hlinku 2 SK-949 76 Nitra Slovakia ANIRDBS/"Stejarul" Research Centre for Biological Sciences 6 Alexandru cel Bun St. Piatra Neamt 610004 Romania

Humankind draws important benefits from large-scale ecological processes termed ecosystem services, yet the status of several of them is declining. Reliable monitoring methods are essential for tracking the status of ecosystem services. Predation is the mainstay of natural pest control, a key ecosystem service. We used green plasticine caterpillars to monitor predation pressure, and to obtain baseline data on predator activity in transgenic Bt versus non-Bt maize fields in Old and New World countries. Predation pressure was measured at ground and canopy levels using an identical, small-plot experimental design in four European countries (Denmark, Slovakia, Romania and Italy) and Argentina. Total predation rate in maize was l l.7%d^-1 (min. 7.2%d^-1 in Argentina, max. 29.0%d^-1 in Romania). Artificial caterpillars were attacked both by invertebrates (mostly chewing insects with 42.0% of the attack marks, and ants with 7.1%, but also predatory and parasitoid wasps, spiders and slugs), and vertebrates (small mammals 25.5%, and birds 20.2%). Total predation at ground level (15.7%d^-1) was significantly higher than in maize canopies (6.0%d^-1) in all countries, except Argentina. We found no significant differences between predator pressure in Bt versus non-Bt maize plots. The artificial caterpillar method provided comparable, quantitative data on predation intensity, and proved to be suitable for monitoring natural pest control. This method usefully expands the existing toolkit by directly measuring ecological function rather than structure.

关键词： artificial caterpillars ecosystem services mortality sentinel prey transgenic plants