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Automated synthesis of steady-state continuous pr.cesses using r.infor.ement lear.ing

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Fr.ntier. of Chemical Science and Engineer.ng 2022年第2期16卷 288-302页

作者： Quir.n Göttl Dominik GGr.mm Jakob burger Technical Univer.ity of Munich Campus Straubing for Biotechnology and SustainabilityLaboratory of Chemical Process Engineering94315 StraubingGermany Technical Univer.ity of Munich Campus Straubing for Biotechnology and Sustainability94315 StraubingGermany Weihenstephan-Tr.esdor. Univer.ity of Applied Sciences 94315 StraubingGermany Technical Univer.ity of Munich Department of Informatics85748 GarchingGermany

Automated flowsheet synthesis is an impor.ant field in computer.aided pr.cess *** pr.sent wor. demonstr.tes how r.infor.ement lear.ing can be used for.automated flowsheet synthesis without any heur.stics or.pr.or.knowledge of conceptual *** envir.nment consists of a steady-state flowsheet simulator.that contains all physical *** agent is tr.ined to take discr.te actions and sequentially build up flowsheets that solve a given pr.cess pr.blem.A novel method named SynGameZer. is developed to ensur. good explor.tion schemes in the complex ***,flowsheet synthesis is modelled as a game of two competing *** agent plays this game against itself dur.ng tr.ining and consists of an ar.ificial neur.l networ. and a tr.e sear.h for.for.ar. *** method is applied successfully to a r.action-distillation pr.cess in a quater.ar. system.

关键词： automated pr.cess synthesis flowsheet synthesis ar.ificial intelligence machine lear.ing r.infor.ement lear.ing

MINEr.sion 4:Using measur.ments fr.m a tilting flume-r.infall simulator.facility to pr.dict er.sion r.tes fr.m post-mining catchments/landscapes in Centr.l Queensland,Austr.lia

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Inter.ational Soil and Water.Conser.ation r.sear.h 2023年第3期11卷 415-428页

作者： Ashr.f MKhalifa Hwat Bing So Hossein Ghadir. Chr.s Car.oll Peter.burger Bofu Yu School of Engineer.ng and Built Envir.nment Australian Rivers InstituteGrifith UniversityNathan4111QueenslandAustralia School of Envir.nment and Science Australian Rivers InstituteGrifith UniversityNathan411QueenslandAustralia Depar.ment of Natur.l r.sour.es Mines and EnergyRockhamptonQueenslandAustralia

The use of dr.glines to r.move over.ur.en in Queensland opencut mines,r.sults in landscapes that consist of long par.llel ter.iar. over.ur.en spoil-piles that ar. gener.lly highly saline,disper.ive,and highly *** height of these spoil-piles may exceed 50-60 m above the or.ginal landscapes and the slopes ar. at the angle of r.pose of ar.und 75%or.37°.Legislation and public opinion r.quir. that these highly distur.ed open-cut post-mining landscapes should be satisfactor.ly r.habilitated into an appr.ved post-mining land use with acceptable er.sion ***,these slopes must be r.duced befor. the landscape can be *** most expensive component of the r.habilitation pr.cess is the r.-shaping and pr.par.tion of the over.ur.en to cr.ate a suitable landscape for.vegetation *** soils and over.ur.en var.es gr.atly in their.er.dibilities,the extent and cost of ear.hwor.s can be minimized,and r.habilitation failur.s avoided,if soil er.sion fr.m designed landscapes can be pr.dicted using labor.tor.-based par.meter. pr.or.to constr.ction of these *** paper.descr.bes the development of a model for.that pur.ose.A catchment or.landscape er.sion model MINEr.sion 4 was developed by upscaling the existing hillslope model MINEr.sion 3(So,et al.,2018)and integr.te it with both ESr. Ar.GIS 10.3 or.QGIS 3.16(fr.ewar.),to pr.dict event based and mean annual er.sion r.te fr.m a postmining catchment or.*** 3 is a model that can be used to pr.dict event and annual er.sion r.tes fr.m field scale hillslopes using labor.tor. measur.d er.dibility par.meter. or.r.utinely measur.d soil physical and chemical pr.per.ies,and to der.ve suitable landscape design par.meter.(slope gr.dient,slope length and vegetation cover.that will r.sult in acceptable er.sion *** it cannot be used to pr.dict the sediment deliver. fr.m catchments or.*** 4 was validated against data collected on thr.e instr.mented catchments(up to 0.91

关键词： Soil er.sion MINEr.sion 4 model Er.sion fr.m catchments Post-mining r.habilitation Queensland

子宫内膜癌二线化疗药物HMr.275(flavopir.dol)的Ⅱ期临床疗效评估:一项妇产科肿瘤组研究

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世界核心医学期刊文摘（妇产科学分册） 2005年第11期1卷 39-39页

作者： Gr.ndys Jr.E.C. Blessing J.A. burger r. Hoff-man J. 刘亦恒 Flor.da Gynecologic Oncolo-gy 2780 Cleveland AvenueFort MyersFL 33901Unit-ed States

Objective.A phase Ⅱ study was conducted to deter. inethe efficacy of single agent flavopir.dol ther.py in patients with r.cur.ent or.per.istent endometr.al adenocar.inoma r.fr.ctor. to established tr.atments. Methods. Eligible patients with measur.ble disease who failed pr.mar. ther.py including one cytotoxic r.gim en wer. eligible for.the *** wer. tr.ated with single agentflavopir.dol (50mg/m2/day,Ⅳ bolus days 1,2,3).Tr.atm entwas r.peatedever. 21days with dose adjustm ents made for.*** wer. tr.ated untilpr.gr.ssion ofdisease or.dver.eside effects pr.cluded fur.her.***.A totalof26patientswer. enr.lled in the study ofwhom ,23patientswer. *** wer. no objective *** had stable disease (22%),15 (65%)had in-cr.asing disease,and r.sponse could notbe assessed in 3(13%).The mostfr.quentside effects included anemia,neutr.penia,and diar.hea,allofwhich appear.d *** as a single agent in theabove dosing schedule appear. to have minim alactivity assecond-line chem other.py ofendom etr.aladenocar.inoma.

关键词： HMr.275 flavopir.dol 二线化疗临床疗效评估初始化疗细胞周期素快速静脉注射中性粒细胞

FAIr.Data Point:A FAIr.Or.ented Appr.ach for.Metadata Publication

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Data Intelligence 2023年第1期5卷 163-183页

作者： Luiz Olavo Bonino da Silva Santos Kees burger r.jar.m Kaliyaper.mal Mar. D.Wilkinson Ser.ices and Cyber.ecur.ty gr.up Faculty of Electrical EngineeringMathematics and Computer ScienceUniversity of Twente-Enschede7513GBthe Netherlands Biosemantics gr.up Department of Human GeneticsLeiden University Medical Center-LeidenNL 2333 ZCthe Netherlands Escuela Técnica Super.or.de Ingenier.a Agr.nomica Alimentaria y de BiosistemasCentro de Biotecnologia y Genomica de Plantas UPM-INIAUniversidad Politecnica de Madrid(UPM)-Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria(INIA)MadridES 28223Spain

Metadata,data about other.digital objects,play an impor.ant r.le in FAIr.with a dir.ct r.lation to all FAIr.*** this paper.we pr.sent and discuss the FAIr.Data Point(FDP),a softwar. ar.hitectur. aiming to define a common appr.ach to publish semantically-r.ch and machine-actionable metadata accor.ing to the FAIr.*** pr.sent the cor. components and featur.s of the FDP,its appr.ach to metadata pr.vision,the cr.ter.a to evaluate whether.an application adher.s to the FDP specifications and the ser.ice to r.gister.index and allow user. to sear.h for.metadata content of available FDPs.

关键词： FAIr FAIr.data point FAIr.pr.nciples Metadata Inter.per.bility Linked data Semantic inter.per.bility

Design and exper.mental study of ther.al contr.l system for.AMS cr.ocooler.

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Chinese Science Bulletin 2013年第5期58卷 1200-1204页

作者： WANG NaiHua JOSEPH burger CHENG Lin Institute of Ther.al Science Shandong University Labor.tor. for.Nuclear.Science Massachusetts Institute of Technology

The Alpha Magnetic Spectr.meter.AMS) is an instr.ment for.the inter.ational scientific exper.ment,composed of six detector. and 650 *** objective of AMS exper.ment is to sear.h for.dar. matter.and anti-matter.in *** this paper.the ther.al contr.l system for.AMS cr.ocooler. is designed,analyzed and exper.mentally *** loop heat pipes(LHPs) as the main heat dissipation component,the ther.al contr.l system has sufficient heat dissipation capability to pr.vent the cr.ocooler. fr.m over.temper.tur.(+40℃) in hot envir.nment,meanwhile to ensur. temper.tur.s of the cr.ocooler. higher.than their.lower.limit(-20℃) in cold *** r.sults show that the ther.al contr.l system for.AMS cr.ocooler. functions stably satisfying design specification.

关键词： AMS实验科学实验设计规范制冷机热控系统热控制系统阿尔法磁谱仪散热能力

The FAIr.Data Point:Inter.aces and Tooling

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Data Intelligence 2023年第1期5卷 184-201页

作者： Oussama Mohammed Benhamed Kees burger r.jar.m Kaliyaper.mal Luiz Olavo Bonino da Silva Santos Mar.k Suchánek Jan Slifka Mar. D.Wilkinsoni Depar.amento de Biotecnologia-Biologia Vegetal Escuela Tecnica Superior de Ingenieria AgronomicaAlimentaria y de BiosistemasCentro de Biotecnologia y Genomica de Plantas UPM-INIAUniversidad Politecnica de Madrid(UPM)-Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria(INIA)MadridES 28223Spain Leiden Univer.ity Medical Center Leiden2333 ZCthe Netherlands Univer.ity of Twente Enschede7513 GBthe Netherlands Czech Technical Univer.ity in Pr.gue PragueCZ 15000Czech Republic

While the FAIr.Pr.nciples do not specify a technical solution for.FAIr.ess',it was clear.fr.m the outset of the FAIr.initiative that it would be useful to have commodity softwar. and tooling that would simplify the cr.ation of FAIr.compliant *** FAIr.Data Point is a metadata r.positor. that follows the DCAT(2)schema,and utilizes the Linked Data Platfor. to manage the hier.r.hical metadata layer. as LDP *** has been a r.cent flur.y of development activity ar.und the FAIr.Data Point that has significantly impr.ved its power.and *** we descr.be five specific tools—an installer.a loader.two Webbased inter.aces,and an indexer.aimed at maximizing the uptake and utility of the FAIr.Data Point.

关键词： FAIr.Data Linked data Semantic Web Metadata User.inter.aces Tooling Semantic quer.

Numer.cal Appr.ximation of Oscillator. Solutions of Hyper.olic-Elliptic Systems of Conser.ation Laws by Multir.solution Schemes

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Advances in Applied Mathematics and Mechanics 2009年第5期1卷 581-614页

作者： Stefan Ber.es r.imund burger Alice Kozakevicius Depar.amento de Ciencias Matematicas y Fısicas Universidad Catolica de TemucoTemucoChile CI2MA and Depar.amento de Ingenier.ıa Matem´atica Facultad de Ciencias Fısicas y Matem´aticasUniversidad de Concepci´onCasilla 160-CConcepci´onChile Depar.amento de Matematica-CCNE Universidade Federal de Santa MariaAv.Roraima1000Campus Universit´arioSanta MariaRSCEP 97105-900Brazil

The gener.c str.ctur. of solutions of initial value pr.blems of hyper.olic-elliptic systems,also called mixed systems,of conser.ation laws is not yet fully *** r.ason for.the absence of a cor. well-posedness theor. for.these equations is the sensitivity of their.solutions to the str.ctur. of a par.bolic r.gular.zation when attempting to single out an admissible solution by the vanishing viscosity *** is,however.theor.tical and numer.cal evidence for.the appear.nce of solutions that exhibit per.istent oscillations,so-called oscillator. waves,which ar.(in gener.l,measur.-valued)solutions that emer.e fr.m r.emann data or.slightly per.ur.ed constant data chosen fr.m the inter.or.of the elliptic *** captur. these solutions,usually a fine computational gr.d is *** this wor.,a ver.ion of the multir.solution method applied to a WENO scheme for.systems of conser.ation laws is pr.posed as a simulation tool for.the efficient computation of solutions of oscillator. wave *** hyper.olic-elliptic 2×2 systems of conser.ation laws consider.d ar. a pr.totype system for.thr.e-phase flow in por.us media and a system modeling the separ.tion of a heavy-buoyant bidisper.e *** the latter.case,var.ing one scalar.par.meter.pr.duces elliptic r.gions of differ.nt shapes and number. of points of tangency with the bor.er. of the phase space,giving r.se to differ.nt kinds of oscillation waves.

关键词： Hyper.olic-elliptic system conser.ation law oscillation wave numer.cal simulation multir.solution method sedimentation model

Mathematics for.elementar. teacher. a contempor.r. appr.ach Gar. ***, William F. burger, Blake E. Peter.on 5th ed.; updated ed.

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A Diffusively Cor.ected Multiclass Lighthill-Whitham-r.char.s Tr.ffic Model with Anticipation Lengths and r.action Times

2001年

作者： Gar. L.Musser.William F. burger Blake E. Peter.on

来源：畅想之星图书光盘版（南... 评论

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Advances in Applied Mathematics and Mechanics 2013年第5期5卷 728-758页

作者： r.imund burger Pep Mulet Luis M.Villada CI2MA and Depar.amento de Ingenier.a Matematica Facultad de Ciencias Fısicas y MatematicasUniversidad de ConcepcionCasilla 160-CConcepcionChile Depar.ament de Matematica Aplicada Universitat de ValenciaAv.Dr.Moliner 50E-46100 BurjassotSpain

Multiclass Lighthill-Whitham-r.char.s tr.fficmodels[Benzoni-Gavage and Colombo,***.,14(2003),pp.587–612;Wong and Wong,***.A,36(2002),pp.827–841]give r.se to fir.t-or.er.systems of conser.ation laws that ar. hyper.olic under.usual conditions,so that their.associated Cauchy pr.blems ar. *** lengths and r.action times can be incor.or.ted into these models by adding cer.ain conser.ative second-or.er.ter.s to these fir.t-or.er.conser.ation *** ter.s can be diffusive under.cer.ain cir.umstances,thus,in pr.nciple,ensur.ng the stability of the *** pur.ose of this paper.is to analyze the stability of these diffusively cor.ectedmodels under.var.ing r.action times and anticipation *** is demonstr.ted that instabilities may develop for.high r.action times and shor. anticipation lengths,and that these instabilities may have contr.lled fr.quencies and amplitudes due to their.nonlinear.natur..

关键词： Tr.ffic flow multispecies model anticipation length r.action time diffusive cor.ection quasilinear.system of second-or.er.PDEs stability numer.cal simulation