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Six Newly Discovered Eclipsing Binary Systems in the TESS field

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Research in Astronomy and Astrophysics 2023年第3期23卷 143-154页

作者： burak ulas Vildan Ayan Department of Space Sciences and Technologies Faculty of Sciences?anakkale Onsekiz Mart UniversityTerzioglu CampusTR 17100CanakkaleTurkey

We present the first detailed investigation of six eclipsing binary systems in the TESS *** TESS light curves of the targets are analyzed by determining the initial effective temperatures via SED *** absolute parameters are derived and the systems are compared to well-known binaries of the same *** show that CD-58791,CD-621257 and TYC 9356-355-1 are detached binary ***-54942 and UCAC4136-007295 are contact binaries while TYC 8508-1413-1 is a semidetached system.

关键词： TESS absolute field

Prognostic factors and clinical features of rhino-orbitalmucormycosis cases:an update for patient and visual survivals

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 916-923页

作者： Mustafa Aksoy Altan Atakan Ozcan burak ulas Department of Ophthalmology Cukurova University Faculty of MedicineSaricamAdana 01330Türkiye

AIM:To determine the frequency of patients’vision survival and prognostic factors and evaluate clinical features in rhino-orbital ***:Forty-three eyes of 43 patients followed up with orbital mucormycosis infections were included in the *** characteristics of the patients,symptoms at admission,ophthalmologic and non-ophthalmologic examination findings,clinical findings during follow-up,medical and surgical procedures,and complications were *** survival was determined by assessing the incidence of mortality,and vision survival was defined as achieving a final visual acuity of at least light ***:Twenty-seven(62.8%)patients were male,and 16(37.2%)were *** the underlying disease status of the patients was examined,it was observed that all patients had an underlying disease and diabetes constituted the majority(65.2%).Periorbital swelling(69.8%)and ophthalmoplegia(53.5%)were the most common symptoms and findings at the admission of patients with mucormycosis *** disease resulted in death in 22(51.2%)*** presence of fever and shorter duration of antifungal therapy were associated with lower patient *** surgery was not found to be associated with the survival of the *** eye,loss of pupillary light reflex,and development of central retinal artery occlusion were associated with lower vision ***:This study presents one of the most extensive patient series in the literature on rhino-orbital *** the patients’symptoms at the time of admission and the clinical findings during the infection process will increase awareness about the disease.

关键词： mucormycosis rhino-orbital-mucormycosis orbital apex syndrome retinal arterial occlusion

Comparison of the inhibitory effect of different doses of subconjunctival bevacizumab application in an experimental model of corneal neovascularization

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International Journal of Ophthalmology(English edition) 2018年第7期11卷 1090-1095页

作者： burak ulas Rana Altan-Yaycioglu Nebil Bal Department of Ophthalmology Baskent University School of Medicine Department of Pathology Baskent University School of Medicine

AIM： To evaluate the inhibitory effect of subconjunctival bevacizumab as single-and multiple-dose application, and compare their effects on corneal neovascularization in a rat model. METHODS： Thirty adult Sprague-Dawley rats were used in this experimental study. The central cornea of the rats was cauterized chemically. The rats were randomly enrolled into three groups. All groups received subconjunctival injections. In Group 1（control group, n=10）, 0.05 m L 0.9% Na Cl solution was injected on the first day. In Group 2（single-dose group, n=10）, 0.05 m L bevacizumab（1.25 mg） was injected on the first day. In Group 3（multiple-dose group, n=10）, four doses of 0.05 m L bevacizumab（1.25 mg） were injected on the first, third, fifth and seventh day. Slit-lamp examination of all rats was performed at the third and ninth day. Digital images of the corneas were taken and analyzed using image analysis software to calculate corneal neovascularization area. All rats were sacrificed on the tenth day. In corneal sections, the number of blood vessels, state of inflammation and collagen formation was evaluated histopathologically. RESULTS： In Group 3, corneal edema grades were significantly lower than Group 1 and Group 2（P=0.02, and P=0.035, respectively）. The mean percentage of neovascularized corneal area in Group 3 was significantly lower than Group 2（P=0.005）. On histopathological examination, Group 2 and Group 3 showed significantly less number of blood vessels than Group 1（P=0.005, and P=0.001, respectively）. Additionally, Group 3 showed significantly less number of blood vessels compared to Group 2（P=0.019）. Inflammation and edema grades were significantly lower in Group 3 compared to Group 1（P=0.001）. CONCLUSION： Subconjunctival bevacizumab injection is effective in inhibition of newly formed corneal neovascularization. The multiple-dose bevacizumab treatment seems to be more effective compared to single-dose treatment.

关键词： cornea corneal neovascularization bevacizumab inflammation rat

Effect of diluted povidone iodine in adenoviral keratoconjunctivitis on the rate of subepithelial corneal infiltrates

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International Journal of Ophthalmology(English edition) 2019年第9期12卷 1420-1425页

作者： Rana Altan-Yaycioglu Nedime Sahinoglu-Keskek Handan Canan Muge Coban-Karatas burak ulas Department of Ophthalmology Baskent University School of Medicine

AIM: To evaluate the clinical characteristics of adenoviral keratoconjunctivitis, the management modalities, as well as the incidence of subepithelial corneal infiltrates(SEI).METHODS: Patients with characteristic clinical symptoms and signs, who presented to our clinic within the first week of symptoms and received the diagnosis of adenoviral keratoconjunctivitis between January 2013 and April 2016, were included in the study. A total of 211 patients were included in the study. Patients were evaluated for the incidence of clinical signs, late complications, management preferences, and the effect of diluted povidone-iodine(d-PVP-I) 2%. RESULTS: Patients’ mean age was 33.03±14.76 y. We observed an increase in the number of cases according to the years. At presentation and/or early follow-up, the clinical signs were conjunctival hyperemia(100%), conjunctival follicules(79.1%), edema of the eyelids(39.3%), chemosis(16.1%), pseudomembrane formation(16.6%), and corneal epitheliopathy(29.9%). During late follow-up 13.3% patients developed conjunctival subepithelial fibrosis, and 39.8% developed SEI. A significant decrease in the incidence of SEI development was observed in patients who used d-PVP-I 2%(P=0.032;33.3% vs 45.9%, respectively in patients who received d-PVP-I 2% and who did not).CONCLUSION: Adenoviral keratoconjunctivitis has a tremendous effect on patient’s comfort and abilities in short-term. Additionally, almost half of the patients develop visual problems related to SEI. According to our clinical experience, using d-PVP-I 2% in the first days of adenoviral keratoconjunctivitis might be helpful in reducing the risk of SEI as a complication.

关键词： conjunctivitis corneal opacity infectious keratoconjunctivitis keratoconjunctivitis povidone-iodine viral conjunctivitis

Choroidal thickness measurements with optical coherence tomography in branch retinal vein occlusion

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International Journal of Ophthalmology(English edition) 2016年第5期9卷 725-729页

作者： Muge Coban-Karatas Rana Altan-Yaycioglu burak ulas Selcuk Sizmaz Handan Canan Cagla Sariturk Department of Ophthalmology Baskent University School of Medicine Department of Ophthalmology Cukurova University School of Medicine Division of Biostatistics Baskent University Adana Clinic and Research Center

AIM： To evaluate central macular thickness（CMT） and mean choroidal thickness（MCT） in eyes with branch retinal vein occlusion（BRVO）, before and after ranibizumab treatment using spectral domain-optical coherence tomography（SD-OCT）.·METHODS： Forty-two patients with unilateral BRVO and macular edema were included in this study. There were 25 men and 17 women. Using SD-OCT, choroidal thickness was measured at 500 μm intervals up to 1500μm temporal and nasal to the fovea. MCT was calculated based on the average of the 7 locations. All the eyes with BRVO were treated with intravitreal ranibizumab（0.5 mg/0.05 m L）. Comparisons between the BRVO and fellow eyes were analyzed using Mann-Whitney U test. Preinjection and post-injection measurements were analyzed using Wilcoxon test and repeated measure analysis.· RESULTS： At baseline, there was a significant difference between the BRVO and fellow eyes in MCT[BRVO eyes 245（165-330） μm, fellow eyes 229（157-327） μm]and CMT [BRVO eyes 463（266-899） μm, fellow eyes 235（148-378） μm（P =0.041, 0.0001, respectively）]. Following treatment, CMT [295（141-558） μm] and MCT [229（157-329） μm] decreased significantly compared to the baseline measurements（P =0.001, 0.006, respectively）.Also BCVA（log MAR） improved significantly（P=0.0001） in the BRVO eyes following treatment. After treatment CMT[BRVO eyes 295（141-558） μm, fellow eyes 234（157-351） μm]and MCT [BRVO eyes 229（157-329） μm, fellow eyes 233（162-286） μm] values did not reveal any significant difference in BRVO eyes and fellow eyes（P=0.051, 0.824,respectively）.· CONCLUSION： In eyes with BRVO, CMT and MCT values are greater than the fellow eyes, and decrease significantly following ranibizumab injection.

关键词： branch retinal vein occlusion choroidal thickness macular edema optical coherence tomography ranibizumab