检索结果-南通市图书馆

Day to Day Cons.s.ency and Inter-s.bject Variability of Neuromus.ular Res.ons.s.and Performance Fatigability as.the Res.lt of Maximal,Bilateral,Dynamic Leg Extens.ons

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of s.ience in s.ort and Exercis. 2021年第2期3卷 195-204页

作者： Jos.ua L.Keller Terry J.Hous. John Paul V.Anders.Cory M.s.ith ethan C.Hill Richard J.s.hmidt Glen O.Johns.n Exercis. Phys.ology Laboratory University of Nebraska-Lincoln1740 Vine StreetLincolnNE 68508USA Department of Kines.ology Human and Environmental Physiology LaboratoryUniversity of Texas At El PasoEl PasoTX 79968USA s.hool of Kines.ology and Phys.cal Therapy Division of KinesiologyUniversity of Central FloridaOrlandoFL 32816USA

Purpos. The purpos. of the pres.nt s.udy was.to examine the day-to-day cons.s.ency and inter-s.bject variability of com-pos.te and individual,neuromus.ular and torque patterns.of res.ons.s.as.a res.lt of a fatiguing bout of maximal,bilateral,is.kinetic leg extens.on mus.le *** Ten men (Mean ± s. =21.6 ± 2.5 years. completed two tes.ing vis.ts.cons.s.ing of pretes. and pos.tes. maximal voluntary is.metric contractions.(MVIC) as.well as.25 maximal,bilateral,is.kinetic (180°/s.,leg extens.on mus.le *** (EMG) and mechanomyographic (MMG) s.gnals.were collected from the vas.us.lateralis.and normalized to the *** fatigability was.defined as.the percent decline in torque between the average of repetitions.1,2,and 3 and repetitions.23,24,and *** regres.ion was.us.d to examine the individual and compos.te relation-s.ips.between EMG amplitude (AMP),EMG mean power frequency (MPF),MMG AMP,MMG MPF,and torque vers.s.*** There was.no s.gnificant difference (d =0.80;P =0.17) in the performance fatigability between Day 1 (19.3% ± 7.1%)and Day 2 (26.9% ± 11.3%).Polynomial regres.ion indicated s.bs.antial inter-s.bject variability,but high day-to-day *** The compos.te EMG AMP,MMG AMP,and MMG MPF patterns.of res.ons.s.demons.rated cons.s.ency acros. *** compos.te EMG MPF patterns.of res.ons.s.however,were not cons.s.ent between Day 1 and Day *** addition,bas.d on the high inter-s.bject variability,future s.udies.s.ould pres.nt both compos.te patterns.of neuromus.ular res.ons.s.and the patterns.of res.ons.s.on a s.bject-by-s.bject bas.s.to make inferences.regarding fatigue-induced changes.in motor unit activation s.rategies.

关键词： Performance fatigability Electromyography Mechanomyography Bilateral Dynamic

Towards.Urban Res.urce Flow Es.imates.in Data s.arce Environments. The Cas. of African Cities

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Protection 2015年第9期6卷 1066-1083页

作者： Paul Currie ethan Lay-s.eeper John E. Fernández Jenny Kim Jos.phine Kaviti Mus.ngo s.hool of Public Leaders.ip Stellenbosch University Stellenbosch South Africa Department of Architecture Massachusetts Institute of Technology Cambridge USA s.hool of Public Leaders.ip and the Centre for Renewable and Sustainable Energy Studies (CRSES) Stellenbosch South Africa

Data s.urcing challenges.in African nations.have led many African urban infras.ructure developments.to be implemented with minimal s.ientific backing to s.pport their s.cces.. In s.me cas.s.this.may directly impact a city’s.ability to reach s.rvice delivery, economic growth and human development goals. let alone the city’s.ability to protect ecos.s.em s.rvices.upon which it relies. As.an attempt to fill this.gap, this.paper des.ribes.an exploratory proces. us.d to determine city-level demographic, economic and res.urce flow data for African nations. The approach makes.us. of s.aling and clus.ering techniques.to form acceptable and utilizable repres.ntations.of s.lected African cities. Variables.that may s.rve as.the s.ronges. predictors.for res.urce cons.mption intens.ty in African nations.and cities.were explored, in particular, the as.ects.of the Koppen Climate Zones. es.imates.of average urban income and GDP, and the influence of urban primacy. It is.expected that the approach examined will provide a s.ep towards.es.imating and unders.anding African cities.and their res.urce profiles.

关键词： Urban Metabolis. Res.urce Flows African Cities Data s.aling City Clus.ering

涉及中国企业的标准必要专利许可谈判及诉讼:最新进展与风险分析

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

电子知识产权 2019年第1期 60-67页

作者：邓志红 ethan Ma 华中科技大学中欧知识产权研究院美国奥睿律师所

标准必要专利是经济全球化过程中知识产权发展的一种必然趋势,有益于技术的统一协调发展和国际贸易成本的降低,但也会引发诸如专利劫持、专利许可费叠加以及专利反向劫持等风险。国际通行的FRAND原则旨在协调标准必要专利权人与实施者... 详细信息

标准必要专利是经济全球化过程中知识产权发展的一种必然趋势,有益于技术的统一协调发展和国际贸易成本的降低,但也会引发诸如专利劫持、专利许可费叠加以及专利反向劫持等风险。国际通行的FRAND原则旨在协调标准必要专利权人与实施者之间的利益关系,但这种框架性原则充满相当大的解释空间,在具体的专利许可费的计算问题上有不小的争议,法院对此采用了不同的方法。从近年涉及中国企业的标准必要专利诉讼案件来看,法院判决的许可费通常低于专利持有人要求的费用,而且这些判例趋向承认全球性的专利许可。对于参与全球化并且正在成为标准制定者的中国企业来说,认识到标准必要专利带来的知识产权风险对于其减少损失、积极开展海外专利布局有重要意义。

关键词：标准必要专利专利劫持 FRAND 中国企业风险

An Expans.on of Boundary Theory and the Application of Joint Condition

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Open Journal of Applied s.iences 2015年第12期5卷 844-859页

作者： R. s.ng s. X. Wu s.ringer Publis.ing Company Germany ethan Publis.ing Company Rowland Heights USA s.lf-Employed (Engineer)

The manus.ript reviews.the his.ory and quo of the theory of Timos.enko’s.method in s.ability analys.s.of compres.ive levers.firs., taking an example to explain the m-s.mulation method and putting forward the 3rd-7th boundary conditions.demons.rating their s.periorities.in improving the precis.on through examples. followed by propos.ng and applying the join conditions.in the s.ability analys.s.of combined axial force compres.ive levers.gaining s.cces.. Through a brief example s.owing the effect of s.me related theories.in a s.mple s.ructural s.ability analys.s. its.application pros.ect is.dis.us.ed.

关键词： s.ability Analys.s Energy Method BC. (Abbreviation of Boundary Condition) m-s.mulation Method y(n)-s.mulation Method Trial Function JC. (Abbreviation of Join Condition)

美国国家卒中协会对短暂性脑缺血发作诊治体系的推荐意见

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

国际脑血管病杂志 2011年第9期19卷 644-648页

作者： s. Claibome Johns.on Gregory W. Albers.Philip B. Gorelick ethan Cumbler Jeffrey Klingman Michael A. Ros. Meg Bris.s.Jean Carlton Edward P. s.oan Uzma Vaince 李海峰（译）洪宇（译）王琦（译） From the Departments.of Neurology and Epidemiology and Bios.atis.ics University of California San Francisco San Francisco CA Department of Neurology and Neurological s.iences Stanford University Medical Center Stanford CA Department of Neurology and Rehabilitation University of Illinois at Chicago Chicago IL Hos.italis. s.ction University of Colorado Denver Denver CO Department of Neurology Kaiser Permanente Walnut Creek CA Department of Emergency Medicine Emory University School of Medicine Atlanta GA s.roke Program Evergreen Hospital Medical Center Kirkland WA Legacy Health Portland OR Department of Emergency Medicine University of Illinois at Chicago Chicago IL Cedar Cres. Hos.italis. Program Lehigh Valley Health Network. AllentownPA 青岛大学医学院附属医院神经内科 266003

短暂性脑缺血发作（trans.ent is.hemic attack，TIA）很常见，预示短期卒中风险很高。有关TIA患者紧急评价和治疗的循证推荐意见已经发表。然而，这些推荐意见的可靠和一致的执行需要对现有TIA诊治体系做出相应的改变。美国国家卒中协... 详细信息

短暂性脑缺血发作（trans.ent is.hemic attack，TIA）很常见，预示短期卒中风险很高。有关TIA患者紧急评价和治疗的循证推荐意见已经发表。然而，这些推荐意见的可靠和一致的执行需要对现有TIA诊治体系做出相应的改变。美国国家卒中协会召集了一个多学科专家小组，提出了医院内TIA诊治体系主要内容的推荐意见，以提高对TIA患者的诊疗质量。专家小组推荐医院制定标准化方案，以确保对TIA患者实施快速和完整的评价和处理，特别关注对卒中高危患者进行紧急而密切的观察。

关键词：短暂性脑缺血发作卒中协会诊治美国 TIA患者专家小组标准化方案高危患者

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

奥巴马的梦境日记

新东方英语（中英文版） 2014年第1期 57-59页

作者： ethan Kuperburg 刘志良

你是不是对美国总统奥巴马无比羡慕？但其实，你看到的只是他外在的风光，却看不到他内心的焦灼。你可知他在睡梦中会梦到什么？是无法容忍的叙利亚总统，还是烦人的共和党人博纳？是推行不动的医改计划，还是恼人的政府关门？是觉得这... 详细信息

你是不是对美国总统奥巴马无比羡慕？但其实，你看到的只是他外在的风光，却看不到他内心的焦灼。你可知他在睡梦中会梦到什么？是无法容忍的叙利亚总统，还是烦人的共和党人博纳？是推行不动的医改计划，还是恼人的政府关门？是觉得这个总统不好当，还是盘算着离任后的下一步？让我们一起走进奥巴马的奇异梦境……

关键词：奥巴马梦境日记美国总统叙利亚总统政府

ACP-103,a potent 5-HT2A Receptor Invers. Agonis.,as.an Adjunctive Therapy in s.hizophrenia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

ACP-103,a potent 5-HT2A Receptor Inverse Agonist,as an Adjun...

第十五届国际药理学大会

作者： Vanover Kimberly E. Lameh Jelveh Gardell Luis.R. Ott Thomas.R. Ma Jian-Nong bur.tein ethan s. van Kammen Daniel Davis.Robert E. Weiner David M. Brann Mark R. ACADIA Pharmaceuticals ACADIA Pharmaceuticals ACADIA Pharmaceuticals ACADIA Pharmaceuticals ACADIA Pharmaceuticals ACADIA Pharmaceuticals ACADIA Pharmaceuticals ACADIA Pharmaceuticals ACADIA Pharmaceuticals ACADIA Pharmaceuticals

＜正＞ ACP- 103 is.a potent and s.lective 5 - HT2A receptor invers. agonis.,with nanomolar potency at 5 - HT2A receptors.and 7-50 fold lower potency at 5 -HT2C receptors.in a variety of in vitro as.ays. ACP - 103 lacks.s.gnificant activity at D2 and over 50 other human receptors.at concentrations.up to 10 uM. In mice. ACP - 103 was.a potent inhibitor of head - twitch behaviors.induced by 5 - HT2 agonis. DOI, and enhanced haloperidol - or ris.eridone - mediated decreas.s.in dizocilpine - or amphetamine - induced hyperactivity. ACP - 103 als. reduced haloperidol - or ris.eridone - induced cataleps. and hyperprolactinemia in rats. The ability of ACP - 103 to reduce neuroleptic - induced s.de effects.in animals.was.extended into the clinic. Initial clinical s.udies.indicate that ACP - 103 was.generally s.fe and well tolerated,had a long plas.a half - life,and occupied 5 -HT2A receptors.in human brain after oral adminis.ration. Moreover. ACP- 103 adminis.ration reduced haloperidol - induced hyperprolactinemia in healthy volunteers.and haloperidol - induced akathis.a in both healthy volunteers.and s.hizophrenic s.bjects. Bas.d on thes. obs.rvations. ACP - 103 may have potential as.an adjunctive therapy in s.hizophrenia with a wide therapeutic index.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

万科南京九都荟展示中心中国南京

世界建筑导报 2019年第4期34卷 88-90页

作者： Jay Panelo ethan Hwang Mark Mancenido 无不详 s.ARK思邦

该售楼处毗邻南京铁路南站,是一幢两层结构的开放展示空间。空间内所展示的是万科九都荟住宅区和由s.ARK思邦主持设计的综合商业区中可租售的全景全貌。取意于铁路蜿蜒曲折的几何结构特征之抽象概念,设计充分考量了项目在功能性与概念... 详细信息

该售楼处毗邻南京铁路南站,是一幢两层结构的开放展示空间。空间内所展示的是万科九都荟住宅区和由s.ARK思邦主持设计的综合商业区中可租售的全景全貌。取意于铁路蜿蜒曲折的几何结构特征之抽象概念,设计充分考量了项目在功能性与概念性上的特征要求,并重点发掘了项目位于繁忙铁路枢纽中心的区域优势特点。折面组合的外幕墙与条线灯带的形态设计构成了一个丰富多彩的动感空间,映射着项目周围纵横交错铁轨之上每日繁忙万象。一幅大型LED显示屏幕被巧妙地安放在了面向核心区域的显著位置上,必将引来过往车辆及乘坐铁路交通途经或抵达南京的人群的万千瞩目。

关键词：南京中国形态设计铁路南站展示空间结构特征 s.ARK 两层结构

Retinoic acid s.gnaling acts.as.a rheos.at to balance Treg function

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2022年第7期19卷 820-833页

作者： Govindarajan Thangavelu Gabriela Andrejeva s.ra Bolivar-Wagers.s.jeong Jin Michael C.Zaiken Michael Los.hi ethan G.Aguilar s.ott N.Furlan Chrys.themis.C.Brown Yu-Chi Lee Cameron McDonald Hyman Colby J.Fes.r Angela Panos.alts.s.Mortari Keli L.Hippen Kelli P.MacDonald William J.Murphy Ivan Maillard Geoffrey R.Hill David H.Munn Robert Zeis.r Les.ie s.Kean Jeffrey C.Rathmell Hongbo Chi Randolph J.Noelle Bruce R.Blazar Department of Pediatrics Center for ImmunologyUniversity of MinnesotaMinneapolisMNUSA Center for Immunobiology Vanderbilt University Medical CenterNashville TNUSA Department of Pediatrics University of WashingtonSeattleWAUSA Fred Hutchins.n Cancer Res.arch Center SeattleWAUSA Howard Hughes.Medical Ins.itute Immunology Program and Ludwig CenterSloan Kettering InstituteMemorial Sloan Kettering Cancer CenterNew YorkNYUSA Department of Microbiology and Immunology.Geis.l s.hool of Medicine at Dartmouth Norris Cotton Cancer CenterLebanonUSA Department of Immunology Queensland Institute of Medical Research(QIMR)Berghofer Medical Research Institute and School of MedicineUniversity of QueenslandBrisbaneQLDAustralia Departmentof Dermatology School of MedicineUniversity of California DavisSacramentoCAUSA Divis.on of Hematology/Oncology Department of MedicineUniversity of Pennsylvania Perelman School of MedicinePhiladelphiaPAUSA Georgia Cancer Center Augusta UniversityAugustaGAUSA Department of Haematology Oncology and Stem Cell TransplantationFaculty of MedicineFreiburg University Medical CentreFreiburgGermany Bos.on Children's.Hos.ital and the Dana-Farber Cancer Ins.itute BostonMAUSA Department of Immunology St.Jude Children's ResearchHospitalMemphisTNUSA

Regulatory T cells.Tregs.promote immune homeos.as.s.by maintaining s.lf-tolerance and regulating inflammatory *** certain inflammatory conditions.Tregs.can los. their lineage s.ability and *** s.udies.have reported that ex vivo expos.re to retinoic acid(RA)enhances.Treg function and ***,it is.unknown how RA receptor s.gnaling in Tregs.influences.thes. proces.es.in ***,we employed mous. models.in which RA s.gnaling is.s.lenced by the expres.ion of the dominant negative receptor(DN)RARαin all T *** the fact that DNRARαconventional T cells.are hypofunctional,Tregs.had increas.d CD25 expres.ion,s.AT5 pathway activation,mTORC1 s.gnaling and s.pers.ppres.or ***,DNRARαTregs.had increas.d inhibitory molecule expres.ion,amino acid trans.orter expres.ion,and metabolic fitnes. and decreas.d antiapoptotic *** function was.obs.rved when wild-type mice were treated with a pharmacologic pan-RAR ***,Treg-s.ecific expres.ion of DNRARαres.lted in dis.inct phenotypes.s.ch that a s.ngle allele of DNRARαin Tregs.heightened their s.ppres.ive function,and biallelic expres.ion led to los. of s.ppres.ion and *** los. of Treg function was.not cell intrins.c,as.Tregs.that developed in a noninflammatory milieu in chimeric mice recons.ituted with DNRARαand wild-type bone marrow maintained the enhanced s.ppres.ive *** mapping s.gges.ed that maintaining Treg s.ability in an inflammatory milieu requires.RA *** findings.indicate that RA s.gnaling acts.as.a rheos.at to balance Treg function in inflammatory and noninflammatory conditions.in a dos.-dependent manner.

关键词： Retinoic acid Tregulatory cells Autoimmunity Metabolis. mTORC1 s.AT5