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Genetic diversity,phylogenetic position and morphometric analysis of Astacus colchicus(Decapoda,Astacidae):a new insight into Eastern European crayfish fauna

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Integrative Zoology 2021年第3期16卷 368-378页

作者： Martin BLÁHA JiríPATOKA Bella JAPOSHVILI Marek LET MilošburˇICˇ Antonín KOUBA Levan MUMLADZE Faculty of Fisheries and Protection of Waters South Bohemian Research Center of Aquaculture and Biodiversity of HydrocenosesUniversity of South Bohemia in CˇeskéBudeˇjoviceVodnˇanyCzech Republic Department of Zoology and Fisheries Faculty of AgrobiologyFood and Natural ResourcesCzech University of Life Sciences PraguePrahaCzech Republic Institute of Zoology of Ilia State University TbilisiGeorgia

The phylogeny of European crayfish fauna,especially with respect to Eastern European species,is still far from being completely *** fill this gap,we analyzed most of the European crayfish species focusing on the phylogenetic position of the endemic crayfish Astacus colchicus,inhabiting *** mitochondrial and one nuclear marker were used to study evolutionary relationships among European crayfish species,resulting in the unique phylogenetic position of *** indicating independent species status to *** analyses revealed a deep molecular divergence of *** in comparison to ***(6.5–10.9%in mtDnA and 1.1%in nDnA)as well as to Pontastacus leptodactylus and ***(5.5–10.0%in mtDnA and 1.4–2.4%in nDnA).Absent ventral process on second male pleopod and abdominal somites II and III with pleura rounded lacking prominent spines clearly indicate taxonomic assignment to the genus Astacus;however,the species is distributed almost in the middle of Ponto-Caspian area typical by occurrence of the genus *** morphological indices linked to head length,carapace,and total body length and width were found to demonstrate apparent differences between *** and *** this study provides a novel insight into European crayfish phylogeography,we also point out the gaps in comprehensive study of the *** species complex,which could reveal details about the potential species status of particular species and subspecies within this genus.

关键词： 12S rRnA 16S rRnA cytochrome c oxidase histone H3 Ponto-Caspian crayfish

Effect of early atopic sensitization in children aged 0–2 years on the development of asthma symptoms at 9–11 years of age

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World Journal of Pediatrics 2022年第11期18卷 753-760页

作者： Himmet Haluk Akar Ebru nadir burçin Beken Yakup Yeşil Division of Pediatric Immunology and Allergy University of Istanbul Health SciencesKanuni Sultan Suleyman Training and Research HospitalIstanbulTurkey Division of Pediatrics University of Istanbul Health SciencesKanuni Sultan Suleyman Training and Research HospitalIstanbulTurkey Department of Pediatric Immunology and Allergy School of MedicineAcibadem Mehmet Ali Aydinlar UniversityIstanbulTurkey

Background Personal genetic predisposition and early life environmental factors are important for the development of childhood *** aimed to search whether egg,milk and mite sensitizations at 0–2 years old are risk factors for asthma symptoms at 9–11 years *** A total of 210 wheezer children who had specific immunoglobulin(Ig)E in 2010–2012 were included in the study(followed by pediatric allergy).Patients were divided into non-atopic(group 1,n=157)and atopic patients[groups 2–7,n=53(5 patients were in both group 4 and group 5)]based on *** the International Study of Asthma and Allergy in Childhood questionnaire,current wheeze(CW,2nd question),exercise wheezing(EW,7th question),and dry cough(DC,8th question)were ***,parental allergies,eczema at 0–2 years,current eosinophil percentage and total IgE were *** Eczema was observed as an important risk factor[CW:odds ratio(OR)=2.83,95%confidence interval(CI)=1.54–5.23,P≤0.001;EW:OR=2.71,95%CI=1.33–5.54,P=0.006;DC:OR=3.03,95%CI=1.47–6.25,P=0.003],whereas having no atopic sensitization at 0–2-year-old(group 1)was found as a significant protective factor for asthma at 9–11 years old(CW:OR=0.32,95%CI=0.15–0.70,P=0.004;EW:OR=0.21,95%CI 0.10–0.44,P≤0.001;DC:OR=0.25,95%CI=0.10–0.59,P=0.002).Conclusion Early personal eczema is a significant risk factor for the development of asthma symptoms at 9–11 years old,whereas not having an allergic sensitization at 0–2 years old(group 1)is an important protective factor.

关键词： Asthma Children Risk factors

Oxidative stress and nitric oxide in rats with alcohol-induced acute pancreatitis

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World Journal of Gastroenterology 2005年第15期11卷 2340-2345页

作者： Gülnur Andican Remisa Gelisgen Ethem Unal Osman Baran Tortum Sergülen Dervisoglu Tayfun Karahasanoglu Gülden bur(?)ak Department of Biochemistry Department of Surgery Department of Pathology

AIM: Oxygen free radical mediated tissue damage is well established in pathogenesis of acute pancreatitis (AP).Whether nitric oxide (nO) plays a deleterious or a protective role is unknown. In alcohol-induced AP, we studied nO, lipooxidative damage and glutathione in pancreas, lung and ***: AP was induced in rats (n = 25) by injection of ethyl alcohol into the common biliary duct. A sham laparatomy was performed in controls (n = 15). After 24 h the animals were killed, blood and tissue sampling were ***: Histopathologic evidence confirmed the development of AP. Marked changes were observed in the pulmonary tissue. Compared with controls, the AP group displayed higher values for nO metabolites in pancreas and lungs, and thiobarbituric acid reactive substances in circulation. Glutathione was lower in pancreas and in circulation. Glutathione and nO were positively correlated in pancreas and lungs of controls but negatively correlated in circulation of experimental group. In the experimental group, plasma thiobarbituric acid reactive substances were negatively correlated with pancreas thiobarbituric acid reactive substances but positively correlated with pancreas ***: nO increases in both pancreas and lungs in AP and nO contributes to the pathogenesis of AP under oxidative stress.

关键词： Thiobarbituric acid reactive substances Glutathione nitric oxide Acute pancreatitis

口服降糖药和胰岛素对眼表治疗的影响(英文)

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国际眼科杂志 2013年第9期13卷 1747-1750页

作者： burin Kklü akιr Yasemin Aslan Katιrcιoglu nurten nlü Hüseyin stün Remzi Kasιm Sunay Duman Bahcelievler市Orkide大街39/5号土耳其巴勒克埃西尔10050 安卡拉培训和研究医院眼科土耳其安卡拉06600

目的:描述和对比口服降糖药(OAD)和胰岛素治疗2型糖尿病患者眼表的效果。方法:在安卡拉卫生部培训和研究医院就诊的20例40眼口服降糖药患者,20例40眼胰岛素治疗患者,对照组的10例非糖尿病人作为研究对象。对所有患者进行常规眼科检查,Sc... 详细信息

目的:描述和对比口服降糖药(OAD)和胰岛素治疗2型糖尿病患者眼表的效果。方法:在安卡拉卫生部培训和研究医院就诊的20例40眼口服降糖药患者,20例40眼胰岛素治疗患者,对照组的10例非糖尿病人作为研究对象。对所有患者进行常规眼科检查,Schirmer试验,泪膜破裂时间分析和结膜印迹细胞学分析.比较三组的泪液功能参数,杯状细胞密度和鳞状上皮化生等级。记录视网膜病变及眼表疾病之间的关系。结果:口服降糖药患者泪膜破裂时间值明显低于其他组(P<0.05)。三组的杯状细胞密度和鳞状上皮化生等级相近。上皮细胞稍大,呈现更多的多边形的眼的中位数级为1级,并且嗜酸性染色胞浆和杯状细胞数量减少。视网膜病变与眼表疾病不相关。结论:口服降糖药患者的角膜前泪膜稳定性比其他组差。各组的印迹细胞学分析结果相似。

关键词：眼表糖尿病印迹细胞学

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WOnCA研究论文摘要汇编——电子病历警报促进结直肠癌筛查项目的效果:初级护理集群的随机对照试验

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中国全科医学 2016年第24期19卷 2990-2990页

作者： GUIRIGUET C MU■OZ-ORTIZ L bur.n A 本刊编辑部

背景结直肠癌筛查的参与率低于被推荐的欧洲目标。目的评估初级护理中电子病历警报的有效性,即与常规护理相比,其增加个人参与有组织的、基于人群的结直肠癌筛查项目的效果。设计与地点西班牙巴塞罗那初级护理中心的整群随机对照试验... 详细信息

背景结直肠癌筛查的参与率低于被推荐的欧洲目标。目的评估初级护理中电子病历警报的有效性,即与常规护理相比,其增加个人参与有组织的、基于人群的结直肠癌筛查项目的效果。设计与地点西班牙巴塞罗那初级护理中心的整群随机对照试验。方法纳入50~59岁接受过免疫化学测试(FIT)的41 042例患者,以及他们的初级保健人员130例,对他们施盲。对照组进行常规初级保健,按照大肠癌筛查计划。干预组除常规护理外,在为期一年的初级护理中纳入健康专业人士建议的电子病历警报以促进筛查。主要观察结果为结直肠癌筛查的参与率和个人参与情况。结果干预组中67位医生和21 619例患者以及对照组中63位医生和19 423例患者是随机选取的。意向处理分析中两组筛查参与率分别为44.1%和42.2%〔OR=1.08,95%CI(0.97,1.20),P=0.146〕。但在调整潜在的混杂因素后,干预组筛查参与率明显升高〔OR=1.11,95%CI(1.02,1.22),P=0.018〕。结论在初级护理中,使用电子病历警报和参与初级护理对提升结直肠癌筛查参与率的显著提升密切相关。

关键词：病史记录汇编结直肠肿瘤随机对照试验学位论文医师摘要和索引(主题) 肿瘤人类

电子病历警报促进结直肠癌筛查项目的效果:初级护理集群的随机对照试验

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中国全科医学 2016年第24期19卷 2990-2990页

作者： GUIRIGUET C MU■OZ-ORTIZ L bur.n A 本刊编辑部

背景结直肠癌筛查的参与率低于被推荐的欧洲目标。目的评估初级护理中电子病历警报的有效性，即与常规护理相比，其增加个人参与有组织的、基于人群的结直肠癌筛查项目的效果。设计与地点西班牙巴塞罗那初级护理中心的整群随机对照试验... 详细信息

背景结直肠癌筛查的参与率低于被推荐的欧洲目标。目的评估初级护理中电子病历警报的有效性，即与常规护理相比，其增加个人参与有组织的、基于人群的结直肠癌筛查项目的效果。设计与地点西班牙巴塞罗那初级护理中心的整群随机对照试验。方法纳入50～59岁接受过免疫化学测试（FIT）的41042例患者，以及他们的初级保健人员130例，对他们施盲。对照组进行常规初级保健，按照大肠癌筛查计划。干预组除常规护理外，在为期一年的初级护理中纳入健康专业人士建议的电子病历警报以促进筛查。主要观察结果为结直肠癌筛查的参与率和个人参与情况。结果干预组中67位医生和21619例患者以及对照组中63位医生和19423例患者是随机选取的。意向处理分析中两组筛查参与率分别为44．1％和42．2％[OR=1．08，95％c，（0．97，1．20），P=0．146]。但在调整潜在的混杂因素后，干预组筛查参与率明显升高[OR=1．11，95％CI（1．02，1．22），P：0．018]。结论在初级护理中，使用电子病历警报和参与初级护理对提升结直肠癌筛查参与率的显著提升密切相关。

关键词：随机对照试验初级护理电子病历癌筛查结直肠 WOnCA 警报论文摘要

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脑梗塞与颅内出血的院外鉴别诊断

德国医学 2001年第4期18卷 233-234页

作者： C.Woisetschlger H.Kittler E.Oschatz A.bur W.Lang U.Waldenhofer A.n.Laggner M.M.Hirschl 周培文 Departmentof Emergency Medicine University of Vienna 华中科技大学同济医学院附属同济医院

脑梗塞和颅内出血是院外常见的病症,入院前将二者正确地区分开是十分重要的,因为涉及到不同的治疗、搬运措施,并对入院后的治疗有指导意义.现行区分两种患者的诊断计分体系需要大量的数据,而这些数据是急诊医生在院外诊断中并不容易获得... 详细信息

脑梗塞和颅内出血是院外常见的病症,入院前将二者正确地区分开是十分重要的,因为涉及到不同的治疗、搬运措施,并对入院后的治疗有指导意义.现行区分两种患者的诊断计分体系需要大量的数据,而这些数据是急诊医生在院外诊断中并不容易获得的.为此,我们进行了一项研究,用院外易获得的临床和回顾性数据建立了一个模型,以帮助区分脑梗塞和颅内出血的主要诊断结果.＃Out-of-hospital diagnosis of cerebral infarction versus intracranial

关键词：脑梗塞颅内出血诊断症状院外鉴别

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滤泡淋巴细胞瘤中增殖类型的免疫组化分析

细胞与分子免疫学杂志 1987年第1期 54-54页

作者： M bur.n Jones,J Vardiman,WA Franklin,黄其全 Department of Pathology University of Chicago Chicago IL 60637 Department of Pathology University of Chicago Chicago IL 60637 Department of Pathology University of Chicago Chicago IL 60637 Department of Pathology University of Chicago Chicago IL 60637

用一种敏感的双标记免疫酶技术,使用一组单克隆抗体,本文对人滤泡B细胞淋巴瘤的细胞成分和增殖类型进行了估价。冰冻组织积块首先用针对增殖细胞的Ki-67抗体染色,然后用对B细胞(To-15)、T细胞(Leu-4)或滤泡树状细胞(R4/23)的抗体染色。... 详细信息

用一种敏感的双标记免疫酶技术,使用一组单克隆抗体,本文对人滤泡B细胞淋巴瘤的细胞成分和增殖类型进行了估价。冰冻组织积块首先用针对增殖细胞的Ki-67抗体染色,然后用对B细胞(To-15)、T细胞(Leu-4)或滤泡树状细胞(R4/23)的抗体染色。分析了13种滤泡淋巴瘤的反应类型,并与2种良性反应结节的结果作了比较。在同一份标本的不同瘤细

关键词：滤泡细胞淋巴瘤生发中心反应中心

Electroantennogram Responses of Iragoides Fasciata Moore (Lepidoptera:Eucleidae) to Some Tea Plant Volatile Compounds

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Electroantennogram Responses of Iragoides Fasciata Moore (Le...