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己内酯及下游行业发展现状及机会展望

化学工业 2024年第1期42卷 12-17页

作者：闫泽卜新平石油和化学工业规划院北京100013 中国石油和化学工业联合会北京100029

综述了国内外己内酯及下游产业的行业发展现状,分析了己内酯在高端聚氨酯、新能源、生物降解材料等领域的市场空间和发展潜力,并对己内酯及下游行业未来发展机会和发展方向进行了展望。

关键词：己内酯高端聚氨酯新能源生物降解材料发展机会展望

2022年后汛期长江口严重咸潮空间分布特征分析

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水电能源科学 2024年第7期42卷 68-72页

作者：乔红杰王金华张志林卜东平长江水利委员会水文局长江口水文水资源勘测局上海200136 南京水利科学研究院江苏南京210029 上海市浦东新区河道管理事务中心上海201200

2022年长江流域出现“汛期反枯”现象,9月长江口河段遭遇了历史罕见的咸潮入侵,对长江口沿江水源地造成严重威胁。为研究2022年后汛期(9~10月)长江口严重咸潮入侵的空间分布,掌握咸潮上溯的最上游位置,基于2022年9~11月长期站实测资料... 详细信息

2022年长江流域出现“汛期反枯”现象,9月长江口河段遭遇了历史罕见的咸潮入侵,对长江口沿江水源地造成严重威胁。为研究2022年后汛期(9~10月)长江口严重咸潮入侵的空间分布,掌握咸潮上溯的最上游位置,基于2022年9~11月长期站实测资料和咸潮应急监测资料及历年实测水文资料,定量分析了长江口咸潮的横向、纵向及垂向分布,结合FVCOM盐度数值模型进行模拟。结果显示,北港水域盐度底表层差异显著,底表层盐度比值平均为25;咸潮最严重时,影响到徐六泾节点段,最上游到达苏通大桥上游约1.0 km。研究结果对长江口应急水源地的规划选址具有指导意义。

关键词：长江口咸潮入侵盐度数值模型空间分布

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CNT@MnO_(2) composite ink toward a flexible 3D printed micro-zinc-ion battery

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Carbon Energy 2022年第3期4卷 446-457页

作者： Yujin Ren Fanbo Meng Siwen Zhang bu ping Hui Li Bosi Yin Tianyi Ma Key Laboratory for Green Synthesis and Preparative Chemistry of Advanced Materials of Liaoning Province Institute of Clean Energy ChemistryCollege of ChemistryLiaoning UniversityShenyangChina Department of Mechanical and Electrical Engineering Xidian UniversityXi'anShanxiChina Centre for Translational Atomaterials Swinburne University of TechnologyHawthornVictoriaAustralia School of Science RMIT UniversityMelbourneVictoriaAustralia

Flexible energy storage devices have played a significant role in multiscenario applications,while flexible zinc-ion batteries(ZIBs),as an essential branch,have developed rapidly in recent ***-dimensional(3D)printing is an extremely advanced technology to design and modify the structure of batteries and provides unlimited possibilities for the diversified development of energy storage ***,by utilizing 3D printing technology,carbon nanotube(CNT)is coated by MnO_(2) to form a flexible CNT@MnO_(2) ink as a cathode for flexible aqueous micro-ZIBs for the first time and zinc powder ink is used as an anode due to its high flexibility and *** Zn//CNT@MnO_(2) flexible battery shows a stable capacity of 63μAh cm^(−2) at 0.4mA cm^(−2).When the battery is bent in different states,the maximum capacity loss compared with the initial value is only 2.72%,indicating its *** study shows the potential of 3D printing technology in the development of flexible manganese-based ZIBs.

关键词： 3D printing carbon nanotubes flexible zinc-ion battery MnO_(2)

Hot metal quality monitoring system based on big data and machine learning

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Journal of Iron and Steel Research(International) 2023年第5期30卷 915-925页

作者： Ran Liu Zhi-feng Zhang Xin Li Xiao-jie Liu Hong-yang Li Xiang-ping bu Jun Zhao Qing Lyu College of Metallurgy&Energy North China University of Science and TechnologyTangshan 063009HebeiChina Hangzhou Pailie Technology Co. Ltd.Hangzhou 310000ZhejiangChina Hebei Iron and Steel Group Tangshan Iron and Steel Co.Ltd.Tangshan 063009HebeiChina

The system of hot metal quality monitoring was established based on big data and machine learning using the real-time production data of a steel enterprise in China.A working method that combines big data technology with process theory was proposed for the characteristics of blast furnace production *** the data have been comprehensively processed,the independent variables that affect the target parameters are selected by using the method of multivariate feature *** use of this method not only ensures the interpretability of the input variables,but also improves the accuracy of the machine learning process and is more easily accepted by *** timely guidance on production,specific evaluation rules are established for the key quality that affects the quality of hot metal on the basis of completed predictions work and uses computer technology to build a quality monitoring system for hot *** online results show that the hot metal quality monitoring system established by relying on big data and machine learning operates stably on site,and has good guiding significance for production.

关键词： Hot metal Big data Machine learning Quality monitoring Feature engineering

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高温环境影响分析及标准测试和设计

环境技术 2024年第1期42卷 14-18页

作者：魏开利李飞卜德平果仕达广电计量检测(北京)有限公司北京100076

环境是影响产品可靠性指标中首要因素,而对电子产品影响最大的环境因素是高温。高温环境下首先会使得电子产品的温升值达到更高的水平,从而使得产品在更短的时间内出现故障,进而寿命终结。而任何电子产品要保证在其规定的高温条件下可... 详细信息

环境是影响产品可靠性指标中首要因素,而对电子产品影响最大的环境因素是高温。高温环境下首先会使得电子产品的温升值达到更高的水平,从而使得产品在更短的时间内出现故障,进而寿命终结。而任何电子产品要保证在其规定的高温条件下可以正常使用,都需要进行相应的高温环境试验,确定产品在高温环境下贮存和使用的适用性。本文首先介绍高温环境对产品的影响以及会引发何种失效模式;随后介绍为保证产品在高温环境下符合应用而制定的相应标准以及标准中规定的测试项目及指标要求;同时,介绍为保证产品高温符合性而一般采取的设计方法。通过对高温环境的影响分析、标准要求及一般的设计方法,为产品高温环境的适用性及及测试提供参考。

关键词：高温标准测试设计

强光及高温诱发白化的中国绿水螅共生细菌多样性的特征

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现代生物医学进展 2024年第8期24卷 1401-1410页

作者：杨凯宁卜莉萍李桂丽段丽丽潘红春安徽师范大学生命科学学院安徽芜湖241000

目的:探究强光及高温诱发白化的中国绿水螅共生细菌多样性的特征。方法:以光照强度2000 Lux和温度25℃条件为对照,分别在强光胁迫(6000 Lux,25℃)、高温胁迫(2000 Lux,33℃)以及强光和高温联合胁迫(6000 Lux,33℃)等3种条件下进行诱导... 详细信息

目的:探究强光及高温诱发白化的中国绿水螅共生细菌多样性的特征。方法:以光照强度2000 Lux和温度25℃条件为对照,分别在强光胁迫(6000 Lux,25℃)、高温胁迫(2000 Lux,33℃)以及强光和高温联合胁迫(6000 Lux,33℃)等3种条件下进行诱导中国绿水螅白化的实验。白化实验进行到21天后,采用对单个水螅细胞中的共生藻进行计数的方法检测绿水螅白化的程度,同时通过16S r DNA高通量测序的方法分析绿水螅共生细菌多样性及丰度变化。结果:在强光胁迫、高温胁迫及强光和高温联合胁迫下绿水螅体内共生藻数量均显著减少(P<0.05)。强光胁迫下绿水螅共生细菌中蓝细菌门(Cyanobacteria)的丰度上升,而在强光和高温联合胁迫下绿水螅共生细菌中不但蓝细菌门的丰度上升,绿硫菌门(Chlorobi)的丰度也明显提高。此外,KEGG富集分析结果表明发生白化的绿水螅共生细菌与亚油酸、类胡萝卜素及甜菜红色素等抗氧化剂的合成和代谢相关。结论:蓝细菌和绿硫菌的光合作用产物有可能被水螅宿主所利用、以弥补水螅宿主由于共生藻的减少带来的营养缺乏;强光和高温胁迫下绿水螅出现白化现象后共生细菌多样性朝有利于提高水螅宿主抗氧化能力的方向发生变化。

关键词：中国绿水螅共生藻白化共生细菌抗氧化能力

Paclitaxel induces human KOSC3 oral cancer cell apoptosis through caspase pathways

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BIOCELL 2024年第7期48卷 1047-1054页

作者： YU-YAN LAN TSUN-CHIH CHENG YI-ping LEE CHIA-YIH WANG bu-MIIN HUANG School of Medicine College of MedicineI-Shou UniversityKaohsiung82445Taiwan Department of Otolaryngology An Nan HospitalChina Medical UniversityTainan70965Taiwan Department of Cell Biology and Anatomy College of MedicineNational Cheng Kung UniversityTainan70101Taiwan Department of Medical Research China Medical University HospitalChina Medical UniversityTaichung40402Taiwan

Background:Paclitaxel is a compound derived from Paciﬁc yew bark that induces various cancer cell ***,whether it also has anticancer activities in KOSC3 cells,an oral cancer cell line,is ***:3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide,ﬂow cytometry,and western blotting assays were carried out to assess cell viability,subG1 phase of the cell cycle,and apoptosis-related protein expression,***:Ourﬁndings indicate that paclitaxel could inhibit cell viability and increase the expression of apoptotic markers,including plasma membrane blebbing and the cleavage of poly ADP-ribose polymerase in KOSC3 ***,the treatment with paclitaxel remarkably elevated the percentage of the subG1 phase in KOSC3 *** addition,treatment with a pan-caspase inhibitor could recover paclitaxel-inhibited cell ***,caspase-8,caspase-9,caspase-7,and BH3 interacting domain death agonist(Bid)were activated in paclitaxel-treated KOSC3 ***:Paclitaxel induced apoptosis through caspase cascade in KOSC3 cells.

关键词： Paclitaxel Oral cancer KOSC3 cells Apoptosis Caspase pathways

Effect　of　remedies　of　supporting　resistance　and　relieving　blood　stasis　on　metastasis　of　postoperative　gastric　cancer　and　ornithine　decarboxylase

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World Journal of Gastroenterology 1997年第2期3卷 72-73页

作者： bu ping

Ｓｕｂｊｅｃｔｈｅａｄｉｎｇｓｓｔｏｍａｃｈｎｅｏｐｌａｓｍｓ／ｓｕｒｇｅｒｙ；ｎｅｏｐｌａｓｍｓｍｅｔａｓｔａｓｉｓ；ｏｒｎｉｔｈｉｎｅｄｅｃａｒｂｏｘｙｌａｓｅ；ｔｒａｄｉｔｉｏｎａｌＣｈｉｎｅｓｅｍｅｄｉｃｉｎ... 详细信息

Ｓｕｂｊｅｃｔｈｅａｄｉｎｇｓｓｔｏｍａｃｈｎｅｏｐｌａｓｍｓ／ｓｕｒｇｅｒｙ；ｎｅｏｐｌａｓｍｓｍｅｔａｓｔａｓｉｓ；ｏｒｎｉｔｈｉｎｅｄｅｃａｒｂｏｘｙｌａｓｅ；ｔｒａｄｉｔｉｏｎａｌＣｈｉｎｅｓｅｍｅｄｉｃｉｎｅＡｂｓｔｒａｃｔＡＩＭＴｏｓｔｕｄｙｔｈｅａｃｔｉｏｎｏｆｒｅｍｅｄｉｅｓｏｆｓｕｐｐｏｒｔｉｎｇｒｅｓｉｓｔａｎｃｅａｎｄｒｅｌｉｅｖｉｎｇｂｌｏｏｄｓｔａｓｉｓｏｎｍｅｔａｓｔａｓｉｓｏｆｐｏｓｔｏｐｅｒａｔｉｖｅｇａｓｔｒｉｃｃａｎｃｅｒａｎｄｉｔｓｉｎｆｌｕｅｎｃｅｏｎｏｒｎｉｔｈｉｎｅｄｅｃａｒｂｏｘｙｌａｓｅ（ＯＤＣ）．ＭＥＴＨＯＤＳＳｉｘｔｙｔｈｒｅｅｐｏｓｔｏｐｅｒａｔｉｖｅｇａｓｔｒｉｃｃａｎｃｅｒｐａｔｉｅｎｔｓｗｅｒｅｒａｎｄｏｍｌｙｄｉｖｉｄｅｄｉｎｔｏｔｗｏｇｒｏｕｐｓ．ＴｈｉｒｔｙｏｎｅｐａｔｉｅｎｔｓｗｅｒｅｔｒｅａｔｅｄｗｉｔｈｗｅｓｔｅｒｎｍｅｄｉｃｉｎｅｃｏｎｓｉｓｔｉｎｇｏｆｔｈｅＦＡＰｓｃｈｅｍｅ（５ｆｌｕｒｏｕｒａｃｉｌ，ａｄｒｉａｍｙｃｉｎａｎｄｃｉｓｐｌａｔｉｎ）ａｎｄｔｈｅＣＯＤＰｓｃｈｅｍｅ（ｃｙｃｌｏｐｈｏｓｐｈａｍｉｄｅ，ｖｉｎｃｒ?

关键词： stomach neoplasms/surgery neoplasms metastasis ornithine decarboxylase traditional Chinese medicine

Hapln1 promotes dedifferentiation and proliferation of iPSC-derived cardiomyocytes by promoting versican-based GDF11 trapping

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Journal of Pharmaceutical Analysis 2024年第3期14卷 335-347页

作者： Ding-Jun Hao Yue Qin Shi-Jie Zhou bu-Huai Dong Jun-Song Yang Peng Zou Li-ping Wang Yuan-Ting Zhao Department of Spine Surgery Honghui HospitalXi'an Jiaotong UniversityXi'an710054China Department of Anesthesiology Honghui HospitalXi'an Jiaotong UniversityXi'an710054China Department of Cardiovascular Medicine Honghui HospitalXi'an Jiaotong UniversityXi'an710054China State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy West China HospitalSichuan UniversityChengdu610041China

Hyaluronan and proteoglycan link protein 1(Hapln1)supports active cardiomyogenesis in zebrafish hearts,but its regulation in mammal cardiomyocytes is *** study aimed to explore the potential regulation of Hapln1 in the dedifferentiation and proliferation of cardiomyocytes and its therapeutic value in myocardial infarction with human induced pluripotent stem cell(hiPSC)-derived cardiomyocytes(CMs)and an adult mouse model of myocardial ***-CMs and adult mice with myocardial infarction were used as in vitro and in vivo models,*** single-cell RNA sequencing data were retrieved for bioinformatic *** results showed that recombinant human Hapln1(rhHapln1)promotes the proliferation of hiPSC-CMs in a dose-dependent *** a physical binding protein of Hapln1,versican interacted with Nodal growth differentiation factor(NODAL)and growth differentiation factor 11(GDF11).GDF11,but not NODAL,was expressed by ***11 expression was unaffected by rhHapln1 ***,this molecule was required for rhHapln1-mediated activation of the transforming growth factor(TGF)-β/Drosophila mothers against decapentaplegic protein(SMAD)2/3 signaling in hiPSC-CMs,which stimulates cell dedifferentiation and *** mouse Hapln1(rmHapln1)could induce cardiac regeneration in the adult mouse model of myocardial *** addition,rmHapln1 induced hiPSC-CM *** conclusion,Hapln1 can stimulate the dedifferentiation and proliferation of iPSC-derived cardiomyocytes by promoting versican-based GDF11 trapping and subsequent activation of the TGF-β/SMAD2/3 signaling ***1 might be an effective hiPSC-CM dedifferentiation and proliferation agent and a potential reagent for repairing damaged hearts.

关键词： Hapln1 Versican GDF11 iPSC-CMs Cardiomyocyte proliferation