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2004英国高血压学会高血压治疗指南(BHS-IV):概要

journal of Cancer Therapy 2021年第6期

作者： Samia M. O’bryan j. Michael Mathis

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英国医学杂志中文版 2004年第5期7卷 273-279页

作者： bryan Williams Neil R Poulter Peter S Sever Morris j Brown Mark Davis Gordon T McInnes john F Potter 邱洪 Department of Cardiovascular Sciences University of Leicester Clinical Sciences Building Leicester Royal Infirmary Leicester professor of medicine International Centre for Circulatory Health Imperial College London and St Mary's Hospital London professor of preventive cardiovascular medicine International Centre for Circulatory Health Imperial College London and St Mary's Hospital London Peter S Sever professor of clinical pharmacology Simon McG Thom reader in medicine Clinical Pharmacology Unit Addenbrooke's Hospital University of Cambridge Cambridge professor of clinical pharmacology Moorfield House Surgery Garforth Leeds general practitioner Section of Clinical Pharmacology and Stroke Medicine Division of Cardiovascular and Medical Sciences Gardiner Institute Western Infirmary University of Glasgow Glasgow professor of clinical pharmacology Ageing and Stroke Medicine Section Department of Cardiovascular Sciences Glenfield Hospital University of Leicester Leicester professor of ageing and stroke medicine the BHS guidelines working party for the British Hypertension Society

在高血压领域，不断出现的新证据已日益受到关注。例如：血压可作为心血管疾病的一个危险因素；改进生活方式对于预防和治疗高血压的重要意义；不同类型药物的有效性和安全性；高危高血压患者包括糖尿病患者的治疗；心血管疾病总体危险... 详细信息

在高血压领域，不断出现的新证据已日益受到关注。例如：血压可作为心血管疾病的一个危险因素；改进生活方式对于预防和治疗高血压的重要意义；不同类型药物的有效性和安全性；高危高血压患者包括糖尿病患者的治疗；心血管疾病总体危险性评估的重要性以及使用他汀类药物所获得的额外益处。

关键词：高血压患者治疗指南心血管疾病高危预防和治疗他汀类药物糖尿病患者概要英国有效性

急性缺血性卒中血管内治疗质量改进的多学会共识

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国际脑血管病杂志 2013年第11期21卷 807-820页

作者： David Sacks Carl M. Black Christophe Cognard john j. Connors Donald Frei Rishi Gupta Tudor G. jovin bryan Kluck Philip M. Meyers Kieran j. Murphy Stephen Ramee Daniel A. Rufenacht M.j. Bernadette Stallmeyer Dierk Vorwerk 皮燕(译) 张莉莉(译) 李敬诚(译) Department of Interventional Radiology Reading Hospital and Medical Center West Reading Center for Neuroendovascular Therapy University of Pittsburgh Medical Center Stroke Institute Pittsburgh The Heart Care Group Allentown Pennsylvania Department of Radiology Utah Valley Regional Medical Center Provo Utah Departments of Radiology Neurological Surgery and Neurology Vanderbilt University Medical Center Nashville Tennessee Department of Neurointerventional Surgery Radiology Imaging Associates and Swedish Medical Center Denver Colorado Department of Neurology Emory Clinic Atlanta Georgia Department of Neurological Surgery Columbia University College of Physicians and Surgeons New York New York Department of Interventional Cardiology Ochsner Medical Center New Orleans Louisiana Diagnostic and Therapeutic Neuroradiology Service Centre Hospitalier Universitaire de Toulouse Hopital Purpan Toulouse France Department of Medical Imaging University of Toronto Toronto Ontario Canada Neuroradiology Division Swiss Neurolnstitute Clinic Hirslanden Zurich Switzerland Institute for Diagnostic and Interventional Radiology Klinikum Ingolstadt Ingolstadt Germany 重庆第三军医大学第三附属医院野战外科研究所神经内科 400042

目的这份国际性多学科共识文件将对急性缺血性卒中诊治过程和临床转归的质量标准进行定义，并希望在质量保证程序中使用这些标准，从而评估和改善急性卒中血运重建的过程和转归。材料和方法写作组成员由美国神经放射学学会、加拿大介入... 详细信息

目的这份国际性多学科共识文件将对急性缺血性卒中诊治过程和临床转归的质量标准进行定义，并希望在质量保证程序中使用这些标准，从而评估和改善急性卒中血运重建的过程和转归。材料和方法写作组成员由美国神经放射学学会、加拿大介入放射学协会、欧洲心血管和介入放射学学会、心血管造影和介入学会、介入放射学学会、神经介入外科学会、欧洲微创神经病学治疗学会以及血管和介入神经病学学会认命。写作组回顾了1986年至2012年2月期间的相关文献，对急性缺血性卒中的诊疗过程和转归进行总结形成一份证据表，然后通过共识设立性能指标和阈值。本指南得到发起学会的批准，并计划在3年后进行全面更新。结果这份国际性多学科共识文件对诊治过程和临床转归的质量标准进行了定义，包括从入院到进行影像学检查、动脉穿刺和血运重建的时间间隔以及90d时的临床转归评估标准。结论本文件为急性缺血性卒中血管内血运重建程序提供了质量改进指南。

关键词：急性缺血性卒中血管内治疗质量改进学会介入放射学临床转归心血管造影质量标准

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应用概率

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County-level USA:No Robust Relationship between Geoclimatic Variables and Cognitive Ability

1982年

作者：（美）沃兹沃思（G.P.Wadsworth）（美）布赖恩（j.G.bryan）林少宫等译

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journal of Geographical Research 2021年第1期4卷 48-66页

作者： bryan j.Pesta john G.R.Fuerst Emil Kirkegaard Cleveland State University United States Ulster Institute for Social Research Denmark

Using a sample of~3,100 ***,we tested geoclimatic explanations for why cognitive ability varies across *** models posit that geoclimatic factors will strongly predict cognitive ability across geography,even when a variety of common controls appear in the regression *** results generally do not support UV radiation(UVR)based or other geoclimatic ***,although UVR alone predicted cognitive ability at the ***-level(β=-.33),its validity was markedly reduced in the presence of climatic and demographic covariates(β=-.16),and was reduced even further with a spatial lag(β=-.10).For climate models,average temperature remained a significant predictor in the regression equation containing a spatial lag(β=.35).However,the effect was in the wrong direction relative to typical cold weather ***,when we ran the analyses separately by race/ethnicity,no consistent pattern appeared in the models containing the spatial *** of gap sizes across counties were also generally inconsistent with predictions from the UVR ***,results seemed to provide support for compositional models.

关键词： Cognitive ability Ultraviolet radiation Climate Geography

Primary Prevention of Cardiovascular Disease

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Cardiovascular Innovations and Applications 2016年第B9期1卷 379-389页

作者： Danny j.Eapen William M.Schultz Robert E.Heinl Nima Ghasemzadeh Tina Varghese Diana E.Kurian Christina E.Mathai Pratik Sandesara bryan R.Kindya Marc P.Allard-Ratick Neal K.Bhatia Ijeoma Isiadinso Laurence Sperling Department of Medicine Emory UniversityAtlantaGAUSA Department of Pharmacy Houston Methodist HospitalHoustonTXUSA Department of Medicine University of South FloridaTampaFLUSA

Cardiovascular disease(CVD)is the leading cause of death *** article focuses on current guidelines for the primary prevention of CVD and addresses management of key risk *** modifi cation,weight loss,exercise,and tobacco use cessation are specifi c areas where focused efforts can successfully reduce CVD risk on both an individual and a societal *** c areas requiring management include dyslipidemia,hypertension,physical activity,diabetes,aspirin use,and alcohol *** preventive efforts have major public health *** the global population continues to grow,health care expenditures will also rise,with the potential to eventually overwhelm the health care *** it is imperative to apply our collective efforts on CVD prevention to improve the cardiovascular health of individuals,communities,and nations.

关键词： cardiovascular disease primary prevention tobacco diabetes dyslipidemia aspirin alcohol exercise

循证指南：弥散和灌注MRI在急性缺血性卒中诊断中的作用美国神经病学学会治疗和技术评价委员会的报告

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国际脑血管病杂志 2010年第11期18卷 801-807页

作者： P.D. Schellinger[] R.N. bryan[] L.R. Caplan[] j.A. Detre[] R.R. Edelman[] C. jaigobin[] C.S. Kidwell[] j.P. Mohr[] M. Sloan[] A.G. Sorensen[] S. Warach[] 章娟娟(译) 王国颖(译) 汪凯(译) National Institutes of Neurological Disorders and Stroke NIH BethesdaMD Department of Neurology University of Erlangen Germany Departments of Radiology University of Pennsylvania Philadelphia Department of Neurology Beth Israel Deaconess Medical Center BostonMA Departments of Neurology University of Pennsylvania Philadelphia Department of Radiology Northwestern University Evanston Division of Neurology Toronto General Hospital Canada Department of Neurology Georgetown University WashingtonDC Columbia University New York NY Department of Neurology University of South Florida Tampa Department of Radiology MGH BostonMA 安徽医科大学第一附属医院神经内科合肥230022

目的评价弥散加权成像（diffusion-weighted imaging,DWI）和灌注加权成像（perfusionweighted imaging PWI）在急性缺血性卒中患者诊断中应用的证据.方法对1966年至2008年1月期间有关DWI和PWI诊断和预后价值的文献进行系统分析.结果... 详细信息

目的评价弥散加权成像（diffusion-weighted imaging,DWI）和灌注加权成像（perfusionweighted imaging PWI）在急性缺血性卒中患者诊断中应用的证据.方法对1966年至2008年1月期间有关DWI和PWI诊断和预后价值的文献进行系统分析.结果和推荐对于发病12 h内的急性缺血性卒中的诊断,DWI已被确认为有效的评价手段,且其诊断价值应高于非增强CT.为了最准确地诊断急性缺血性卒中,应进行DWI（A级推荐）;然而,在疑似急性卒中患者的总体样本中,DWI诊断缺血性卒中的敏感性并不完美.DWI诊断脑出血的准确性不在本指南的范围之内.根据Ⅱ级和Ⅲ级证据,基线DWI体积可预测前循环卒中的基线卒中严重程度（B级推荐）,但不能预测椎基底动脉系统卒中的基线卒中严重程度（C级推荐）.基线DWI病变体积可预测（最终）梗死体积（B级推荐）,并且有可能预测早期和远期临床转归（C级推荐）.与DWI相比,基线PWI体积预测基线卒中严重程度的价值较小（C级推荐）.尚无足够的证据支持或反对PWI在急性缺血性卒中诊断中的价值（U级推荐）.

关键词：急性缺血性卒中弥散加权成像美国神经病学学会循证指南 I诊断灌注MRI 椎基底动脉系统委员会

Troubleshooting a Difficult Trans-Tibial/Fibula Amputation: A Case Report

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Studying Some Brain and Ovarian Morphological Traits in Diaglena spatulata Female Frogs Thriving in Conserved and Perturbed Habitats:A Preliminary Report and Its Implications for Amphibian Survival and Continuity

Surgical Science 2023年第6期

作者： Amy C. Ross Alejandra Navarro Castaneda jared D. Stucki Katharine A. Dishner Marisse A. Lardizabal bryan j. Roth Luis G. Fernandez Samantha A. Delapena Marc R. Matthews

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Advances in Bioscience and Biotechnology 2014年第9期5卷 740-747页

作者： Esperanza Melendez-Herrera bryan Victor Phillips-Farfan Fany Edith Bucio-Pina Noemi Ramirez-Arres Gabriel Gutierrez-Ospina Ireri Suazo-Ortuno javier Alvarado-Diaz Alma Lilia Fuentes-Farias Laboratorio de Ecofisiologia Animal Departamento de ZoologiaInstituto de Investigaciones sobre los Recursos NaturalesUniversidad Michoacana de San Nicolas de HidalgoMoreliaMéxico Laboratorio de Nutricion Experimental Instituto Nacional de PediatriaSecretaria de SaludMexico Distrito FederalMexico Laboratorio de Biologia de Sistemas Departamento de Biologia Celular y FisiologiaInstituto de Investigaciones BiomedicasCoordinacion de Psicobiologia y NeurocienciasFacultad de PsicologiaUniversidad Nacional Autonoma de MexicoMexico Distrito FederalMexico Laboratorio de Ecologia Departamento de ZoologiaInstituto de Investigaciones sobre los Recursos NaturalesUniversidad Michoacana de San Nicolas de HidalgoMoreliaMexico Laboratorio de Herpetologia Departamento de ZoologiaInstituto de Investigaciones sobre los Recursos NaturalesUniversidad Michoacana de San Nicolas de HidalgoMoreliaMexico

Amphibians are thought to be highly susceptible to perturbed environments. However, recent studies show that many of them are successful inhabitants of disturbed, fragmented habitats. The source of this resilience is yet unclear, but it may be the byproduct of having a robust phenotype and/or the result of phenotypic plasticity. We then assessed the contribution of each by evaluating cytological features of two brain nuclei that modulate reproductive behavior and of the ovary, using female specimens of the frog Diaglena spatulata prospering in conserved and disturbed areas of a tropical dry forest. Our results in the brain show that the medial amygdala, but not the preoptic area, had a reduced size in frogs collected in disturbed forests compared to specimens collected in conserved forests. Both brain nuclei displayed, however, neurons with a reduced size in frogs captured in disturbed forest patches. In contrast, ovarian cytological features were similar between groups. Our preliminary results lead us to propose that Diaglena spatulata female specimens might combine robust ovary and plastic brain’s phenotypic traits to confront disturbed environments. This, however, is still a working hypothetical framework that needs to be experimentally confirmed.

关键词： Amphibians Reproductive Traits Amygdala Medial Preoptic Area Ovary

Mobilizing Crop Biodiversity

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Molecular Plant 2020年第10期13卷 1341-1344页

作者： Susan McCouch Zahra Katy Navabi Michael Abberton Noelle L.Anglin Rosa Lia Barbieri Michael Baum Kirstin Bett Helen Booker Gerald L.Brown Glenn j.bryan Luigi Cattivelli David Charest Kellye Eversole Marcelo Freitas Kioumars Ghamkhar Dario Grattipaglia Robert Henry Maria Cleria Valadares Inglis Tofazzal Islam Zakaria Kehel Paul j.Kersey Graham j.King Stephen Kresovich Emily Marden Sean Mayes Marie Noelle Ndjiondjiop Henry T.Nguyen Samuel Rezende Paiva Roberto Papa Peter W.B.Phillips Awais Rasheed Christopher Richards Mathieu Flouard Maria jose Amstalden Sampaio Uwe Scholz Paul D.Shaw Brad Sherman S.Evan Staton Nils Stein jan Svensson Mark Tester jose Francisco Montenegro Valls Rajeev Varshney Stephen Visscher Eric von Wettberg Robbie Waugh Peter Wenzl Loren H.Rieseberg Plant Breeding and Genetics School of Integrated Plant SciencesCornell UniversityIthacaNY14853USA DivSeek Global Institute for Food Security110 Gymnasium PlaceUniversity of SaskatchewanSaskatoonSKS7N 0W9Canada lnternational Institute of Tropical Agriculture(IITA) PMB 5320Oyo RdIbadanNigeria International Potato Center(CIP)1895 Avenida La Molina Lima Peru 12Lima 15023Peru Embrapa Genetic Resources and Biotechnology Parque Estacjao BiologicaFinal Av W5 NorteCaixa Postal 0237270770-917-Brasilia DFBrazil International Center for Agricultural Research in the Dry Areas(I CAR DA) Station Exp.INRA-Quich.Rue Hafiane Cherkaoui.Agdal.Rabat-Instituts10111RabatMorocco Department of Plant Sciences University of Saskatchewan51 Campus Dr.SaskatoonSK S7N 5A8Canada Department of Plant Agriculture University of GuelphRm 316Crop Science Bldg50 Stone Rd EGuelphON N1G 2W1Canada Genome Prairie 111 Research DriveSuite 101SaskatoonSKS7N 3R2Canada The james Hutt on Institute Errol RoadInvergowrieDundeeDD25DAUK CREA Research Centre for Genomics and Bioinformaticsvia San Protaso 302Fiorenzuola d'Arda29017Italy Genome British Columbia 400-575 West 8th AvenueVancouverBCV5Z 0C4Canada International Wheat Genome Sequencing Consortium 2841 NE Marywood CtLee's SummitMO.64086USA Forage Science Grasslands Research CentreAgResearchPalmerston North4410New Zealand Queensla nd Alliance for Agriculture and Food Inn ovation University of QueenslandBrisbaneQLD 4072Australia Institute of Biotechnology and Genetic Engineering(IBGE) Bangabandhu Sheikh Mujibur Rahman Agricultural UniversityGazipur 1706Bangladesh Southern Cross University PO Box 157LismoreNSW 2480Australia Royal Botanic Gardens KewRichmondSurreyTW93AEUK Feed the Future Innovation Lab for Crop Improvement 431 Weill HallCornell UniversityIthacaNY14853USA Department of Botany and Biodiversity Research Centre University of British ColumbiaVancouverBC V6R 2A5Canada Crops For the Future(UK)CIC 76-80 Baddow Road ChelmsfordEs

Over the past 70 years,the world has witnessed extraordinary growth in crop productivity,enabled by a suite of technological advances,including higher yielding crop varieties,improved farm management,synthetic agrochemicals,and agricultural *** this"Green Revolution"intensified crop production,and is credited with reducing famine and malnutrition,its benefits were accompanied by several undesirable collateral effects(Pingali,2012).These include a narrowing of agricultural biodiversity,stemming from increased monoculture and greater reliance on a smaller number of crops and crop varieties for the majority of our *** reduction in diversity has created vulnerabilities to pest and disease epidemics,climate variation,and ultimately to human health(Harlan,1972).

关键词： intensified crops agricultural