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Physical activity volume,frequency,and intensity:Associations with hypertension and obesity over 21 years in Australian women

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Journal of Sport and Health Science 2024年第5期13卷 631-641页

作者： Gregore I.mielke Ding Ding Shelley E.Keating bruno P.Nunes Ruth Brady Wendy J.Brown School of Public Health The University of QueenslandBrisbaneQLD 4006Australia Sydney School of Public Health Faculty of Medicine and HealthThe University of SydneySydneyNSW 2006Australia The Charles Perkins Centre The University of SydneySydneyNSW 2006Australia School of Human movement and Nutrition Sciences The University of QueenslandBrisbaneQLD 4072Australia School of Nursing Federal University of PelotasPelotasRio Grande do Sul 96010-610Brazil Faculty of Health Sciences and medicine Bond UniversityGold CoastQLD 4226Australia

Background:Optimal patterns of accrual of recommended levels of physical activity(PA)for prevention of hypertension and obesity are not *** overall aim of this study was to investigate whether different patterns of accumulation of PA are differentially associated with hypertension and obesity in Australian women over 21 ***,we investigated whether,for the same weekly volume of PA,the number of sessions(frequency)and vigorousness of PA(intensity)were associated with a reduction in the occurrence of hypertension and obesity in ***:Data from the 1973-1978 and 1946-1951 cohorts of the Australian Longitudinal Study on Women's Health were analyzed(n=20,588;12%-16%with a Bachelor's or higher degree).Self-reported PA,hypertension,height,and weight were collected using mail surveys every 3 years from 1998/2000 to 2019/*** Estimating Equation models with a 3-year lag model were used to investigate the association of PA volume(metabolic equivalent min/week)(none;33-499;500-999;≥1000,weekly frequency(none;1-2 times;3-4times;5-7 times;≥8 times),and the proportion of vigorous PA to total volume of PA(none;0%;1%-33%;34%-66%;67%-100%)with odds of hypertension and obesity from 2000 to ***:The cumulative incidence of hypertension was 6%in the 1973-1978 and 23%in the 1946-1951 cohort;27%of women in the 1973-1978;and 15%in the 1946-1951 cohort developed obesity over the ***,a higher volume of PA was associated with reduced odds of hypertension and *** the volume of PA was considered,the odds of hypertension did not vary according to the frequency or intensity of ***,increased proportion of vigorous PA to the total volume of PA was associated with a small additional reduction in the risk of obe ***:PA volume appears to be more important than the pattern of accumulation for the prevention of hypertension and *** more sessions,particularly of vigorous-intensity PA,may provide extr

关键词： Physical activity Frequency Intensity Incidences Epidemiology Women

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Nonsteroidal anti-inflammatory drugs before endoscopic ultrasound guided tissue acquisition to reduce the incidence of post procedural pancreatitis

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World Journal of Gastroenterology 2024年第8期30卷 811-816页

作者： mike de Jong Foke van Delft Christine Roozen Erwin-Jan van Geenen Tanya Bisseling Peter Siersema marco bruno Department of Gastroenterology and Hepatology Radboud University Medical CenterNijmegen 6525 GANetherlands Department of Gastroenterology and Hepatology Erasmus University Medical CenterRotterdam 3015 GDNetherlands

Endoscopic ultrasound(EUS)with fine needle aspiration or fine needle biopsy is the gold standard for sampling tissue to diagnose pancreatic cancer and auto-immune pancreatitis or to analyze cyst *** most common reported adverse event of fine needle aspiration and/or fine needle biopsy is acute pancreatitis,which is likely induced by the same pathophysiological mechanisms as after en-doscopic retrograde cholangiopancreatography(ERCP).According to the current European Society of Gastrointestinal Endoscopy guideline,nonsteroidal anti-inflammatory drugs are administered prior to ERCP as a scientifically proven treatment to reduce post-ERCP pancreatitis incidence rate.A single suppository of diclofenac or indomethacin prior to EUS guided tissue acquisition(TA)is harm-less in healthy *** it is associated with low costs and,most important,may prevent a dreadsome complication,we strongly recommend the adminis-tration of 100 mg diclofenac rectally prior to *** will explain this recom-mendation in more detail in this review as well as the risk and pathophysiology of post-EUS TA pancreatitis.

关键词： Pancreatitis Endoscopic ultrasound Tissue acquisition Nonsteroidal antiinflammatory drugs Pancreatic cancer

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Demonstrating grating-based phase-contrast imaging of laser-driven shock waves

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matter and Radiation at Extremes 2024年第4期9卷 90-97页

作者： Leonard Wegert Stephan Schreiner Constantin Rauch bruno Albertazzi Paulina Bleuel Eric Frojdh michel Koenig Veronika Ludwig Artem Smartynenko Pascal meyer Aldo mozzanica michael müller Paul Neumayer markus Schneider Angelos Triantafyllidis Bernhard Zielbauer Gisela Anton Thilo michel Stefan Funk Plasma Physics Department GSI Helmholtzzentrum fur SchwerionenforschungPlanckstraBe 164291 DarmstadtGermany Erlangen Centre for Astroparticle Physics(ECAP) Friedrich-Alexander-Universität Erlangen-NurnbergNikolaus-Fiebiger-StraBe 291058 ErlangenGermany LULI-CNRS CEASorbonne UniversitésEcole PolytechniqueInstitut Polytechnique de ParisF-91120 Palaiseau CedexFrance Paul Scherrer Institut(Psi) Forschungsstrasse 1115232VilligenSwitzerland Karlsruhe Institute of Technology Institute of Microstructure TechnologyHermann-von-Helmholtz-Platz 176344 Eggenstein-LeopoldshafenGermany

Single-shot X-ray phase-contrast imaging is used to take high-resolution images of laser-driven strong shock *** a two-grating Talbot interferometer,we successfully acquire standard absorption,differential phase-contrast,and dark-field images of the shocked *** agreement is demonstrated between experimental data and the results of two-dimensional radiation hydrodynamics simulations of the laser-plasma *** main sources of image noise are identified through a thorough assessment of the interferometer’s *** acquired images demonstrate that grating-based phase-contrast imaging is a powerful diagnostic tool for high-energy-density *** addition,we make a novel attempt at using the dark-field image as a signal modality of Talbot interferometry to identify the microstructure of a foam target.

关键词： interaction. shock phase

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Assessment of the performance of the TOPGNSS and ANN-mB antennas for ionospheric measurements using low-cost u-blox GNSS receivers

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Geodesy and Geodynamics 2024年第3期15卷 291-301页

作者： Daniel Okoh Aderonke Obafaye Oluwakemi Dare-Idowu Babatunde Rabiu Anton Kashcheyev Claudio Cesaroni John Bosco Habarulema bruno Nava United Nations African Regional Centre for Space Science and Technology Education-English(UN-ARCSSTE-E) Obafemi Awolowo University CampusIle IfeNigeria National Institute for Geophysics and Volcanology(INGV) 00143 RomeItaly Institute for Space Science and Engineering African University of Science and TechnologyAbujaNigeria University of New Brunswick FrederictonCanada South African National Space Agency(SANSA) P.O Box 32Hermanus 7200South Africa Department of Physics and Electronics Rhodes University6140 MakhandaSouth Africa The Abdus Salam International Centre for Theoretical Physics Strada Costiera11I-34151 TriesteItaly

Low-cost GNSS receivers have recently been gaining reliability as good candidates for ionospheric studies. In line with these gains are genuine concerns about improving the performance of these receivers. In this work, we present a comprehensive investigation of the performances of two antennas(the u-blox ANN-mB and the TOPGNSS TOP-106) used on a low-cost GNSS receiver known as the u-blox ZED-F9P. The two antennas were installed on two identical and co-located u-blox receivers. Data used from both receivers cover the period from January to June 2022. Results from the study indicate that the signal strengths are dominantly greater for the receiver with the TOPGNSS antenna than for the receiver with the ANN-mB antenna, implying that the TOPGNSS antenna is better than the ANN-mB antenna in terms of providing greater signal strengths. Summarily, the TOPGNSS antenna also performed better in minimizing the occurrence of cycle slips on phase TEC measurements. There are no conspicuous differences between the variances(computed as 5-min standard deviations) of phase TEC measurements for the two antennas, except for a period around may-June when the TOPGNSS gave a better performance in terms of minimizing the variances in phase TEC. Remarkably, the ANN-mB antenna gave a better performance than the TOPGNSS antenna in terms of minimizing the variances in pseudorange TEC for some satellite observations. For precise horizontal(North and East) positioning, the receiver with the TOPGNSS antenna gave better results, while the receiver with the ANN-mB antenna gave better vertical(Up) positioning. The errors for the receivers of both antennas are typically within about 5 m(the monthly mean was usually smaller than 1 m) in the horizontal direction and within about 10 m(the monthly mean was usually smaller than 4 m) in the vertical direction.

关键词： GNSS Ionosphere Low-cost Antenna TOPGNSS U-blox

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ENSO impacts on litter stocks and water holding capacity in secondary forests in eastern Amazonia

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Journal of Forestry Research 2024年第1期35卷 83-89页

作者： Julia Isabella de matos Rodrigues Walmer bruno Rocha martins Victor Pereira de Oliveira myriam Suelen da Silva Wanzerley Hélio Brito dos Santos Júnior Francisco de Assis Oliveira Graduate Program in Forestry Sciences Av.Presidente Tancredo Neves2501BelémPará66077-530Brazil Federal Rural University of Amazonia Av.Presidente Tancredo Neves2501BelémPará66077-530Brazil Federal Rural University of Amazonia Tv.Pau-AmareloCapitão PoçoPará68650-000Brazil National Institute of Amazonia Research Av.Constelação Cruzeiro do SulManausAmazonas 69060-062Brazil

Among the impacts of climate change,there is the intensification of phenomena such as the El Niño South-ern Oscillation(ENSO)responsible for El Niño and La Niñ***,understanding their effects on the functional pro-cesses of forests is ***,this study evaluated the effects of ENSO on litter stock and water holding capac-ity(WHC)in a successional forest in eastern *** occurred in periods with the most rainfall in El Niño(2019)and least in La Niña(2021)*** permanent plots were used to sample *** effects were evident for WHC,higher during El Niñ***,this influence was not clear for litter,as only in the rainy season effects were *** was a positive correlation of WHC with precipitation and humidity,while litter stocks were negatively correlated with temperature and wind *** the subject of this study requires long-term assessments,preliminary results suggests that,depending on the intensity of ENSO,forest functional processes can be strongly impacted and *** conclusion reinforces warnings by the scientific community about the impacts of climate change on the maintenance of litter stocks,decomposition and,consequently,the biogeochemical cycle and essential ecosystem services for the maintenance of Amazonia *** need to develop long-term research to understand the effects of climatic change on litter stocks and water holding capacity is highlighted,especially in Amazonia.

关键词： Seasonality Climate change Succession ecosystem Biogeochemical cycle Amazonia biodiversity

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Effect of resistance training volume on body adiposity,metabolic risk,and inflammation in postmenopausal and older females:Systematic review and meta-analysis of randomized controlled trials

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Journal of Sport and Health Science 2024年第2期13卷 145-159页

作者： Paulo Ricardo Prado Nunes Pamela Castro-e-Souza Anselmo Alves de Oliveira bruno de Freitas Camilo Gislaine Cristina-Souza Lucio marques Vieira-Souza marcelo Augusto da Silva Carneiro Department of Body and Human movement Minas Gerais State University(UEMG)37902-092 PassosMGBrazil University Center of Planalto de Araxa(UNIARAXA) 38180-129 AraxaMGBrazil Physical Activity Health and Ageing Research Group(GPASE)Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Exercise and Nutrition Research Group(GPEN) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Sport Sciences and Physical Exercise Study and Research Group(GEPCEEX) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil metabolism Nutrition and Exercise LaboratoryPhysical Education and Sport CenterLondrina State University(UEL)86050-070 LondrinaPRBrazil Postgraduate Program in Physical Education Federal University of Sergipe(UFS)49107-230 Sao CristovaoSEBrazil

Purpose:This meta-analytical study aimed to explore the effects of resistance training(RT) volume on body adiposity,metabolic risk,and inflammation in postmenopausal and older ***:A systematic search was performed for randomized controlled trials in Pubmed,Scopus,Web of Science,and *** controlled trials with postmenopausal and older females that compared RT effects on body adiposity,metabolic risk,and inflammation with a control group(CG) were *** reviewers selected the studies,extracted the data,and performed the risk of bias and certainty of the evidence(Grading of Recommendations,Assessment,Development,and Evaluation(GRADE)) *** body and abdominal adiposity,blood lipids,glucose,and C-reactive protein were included for meta-analysis.A random-effects model,standardized mean difference(Hedges’ g),and 95% confidence interval(95%CI) were used for ***:Twenty randomized controlled trials(overall risk of bias:some concerns;GRADE:low to very low) with overweight/obese postmenopausal and older females were *** groups were divided into low-volume RT(LVRT,~44 sets/week) and high-volume RT(HVRT,~77 sets/week).Both RT groups presented improved body adiposity,metabolic risk,and inflammation when compared to ***,HVRT demonstrated higher effect sizes than LVRT for glucose(HVRT=-1.19;95%CI:-1.63 to-0.74;LVRT=-0.78;95%CI:-1.15 to-0.41) and C-reactive protein(HVRT=-1.00;95%CI:-1.32 to-0.67;LVRT=-0.34;95%CI,-0.63 to-0.04)) when compared to ***:Compared to CG,HVRT protocols elicit greater improvements in metabolic risk and inflammation outcomes than LVRT in overweight/obese postmenopausal and older females.

关键词： C-reactive protein Fat mass Lipid profile menopause Strength training

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Driving factors behind multiple populations

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Science China(Physics,mechanics & Astronomy) 2024年第5期67卷 172-181页

作者： Ruoyun Huang Baitian Tang Chengyuan Li Doug Geisler mario mateo Ying-Yi Song Holger Baumgardt Julio A.Carballo-Bello Yue Wang Jundan Nie bruno Dias JoséG.Fernández-Trincado School of Physics and Astronomy Sun Yat-sen UniversityZhuhai 519082China CSST Science Center for the Guangdong-Hong Kong-macao Greater Bay Area Zhuhai 519082China Departamento de Astronomía Universidad de ConcepcionConcepcionChile Instituto de Investigación multidisciplinario en Ciencia y Tecnología Universidad de La SerenaLa SerenaChile Departamento de Astronomía Facultad de CienciasUniversidad de La SerenaChile Department of Astronomy University of MichiganAnn Arbor 48109USA David A.Dunlap Department of Astronomy&Astrophysics University of TorontoToronto ON M5S 3H4Canada Dunlap Institute for Astronomy&Astrophysics University of TorontoToronto ON M5S 3H4Canada School of mathematics and Physics The University of QueenslandSt.Lucia QLD 4072Australia Instituto de Alta Investigación Universidad de TarapacáAricaChile CAS Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China Instituto de Astrofísica Departamento de Ciencias FísicasFacultad de Ciencias ExactasUniversidad Andres BelloSantiagoChile Instituto de Astronomía Universidad Católica del NorteAntofagastaChile

Star clusters were historically considered simple stellar populations,with all stars sharing the same age and initial chemical ***,the presence of chemical anomalies in globular clusters(GCs),called multiple stellar populations(mPs),has challenged star formation theories in dense *** studies show that mass,metallicity,and age are likely controlling parameters for the manifestation of *** the limit between clusters with/without mPs in physical parameter space is crucial to reveal the driving mechanism behind their *** this study,we look for mP signals in Whiting 1,which is traditionally considered a young *** the magellan telescope,we obtained low-resolution spectra withinλλ=3850-5500?for eight giants of Whiting *** measured the C and N abundances from the CN and CH spectral indices.C and N abundances have variations comparable with their measurement errors(~0.1 dex),suggesting that mPs are absent from Whiting *** these findings with literature studies,we propose a limit in the metallicity *** compactness index parameter space,which relatively clearly separates star clusters with/without mPs(GCs/open clusters).This limit is physically *** a larger scale,the galactic environment determines cluster compactness and metallicity,leading to metal-rich,diffuse,old clusters formed ex *** proposed limit also impacts our understanding of the formation of the Sagittarius dwarf galaxy:star clusters formed after the first starburst(age≤8-10 Gyr).These clusters are simple stellar populations because the enriched galactic environment is no longer suitable for mP formation.

关键词： stellar galactic galaxy

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Associations between physical activity levels and ATPase inhibitory factor 1 concentrations in older adults

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Journal of Sport and Health Science 2024年第3期13卷 409-418页

作者： Jérémy Raffin Yves Rolland Annelise Genoux Guillaume Combes mikael Croyal Bertrand Perret Sophie Guyonnet bruno Vellas Laurent O.martinez Philipe de Souto Barreto For the mAPT/DSA Group Institut du Vieillissement Gérontopôle de ToulouseCentre Hospitalo-Universitaire de ToulouseToulouse 31000France Centre d'Epidémiologie et de Recherche en Santédes Populations UnitéMixte de Recherche 1295Institut National de la Santéet de la Recherche MédicaleUniversitéToulouse-III-Paul-SabatierToulouse 31000France LimitAging Team Institut des Maladies Métaboliques et CardiovasculairesUnitéMixte de Recherche 1297Institut National de la Santéet de la Recherche MédicaleUniversitéToulouse III-Paul SabatierToulouse 31432France Service de Biochimie Pôle de biologieHôpital de PurpanCentre Hospitalo-Universitaire de ToulouseToulouse 31300France L'Institut du Thorax Institut National de la Santéet de la Recherche MédicaleCentre National de la Recherche ScientifiqueCentre Hospitalo-Universitaire de NantesNantes UniversitéNantes 44000France BioCore US16Structure Fédérative de Recherche BonamyInstitut National de la Santéet de la Recherche MédicaleCentre National de la Recherche ScientifiqueCentre Hospitalo-Universitaire de NantesNantes UniversitéNantes 44000France Plate-forme de spectrométrie de masse Centre de Recherche en Nutrition HumaineOuestNantes 44000France 不详

Background:Adenosine triphosphatase inhibitory factor 1(IF1)is a key protein involved in energy ***1 has been linked to various agerelated diseases,although its relationship with physical activity(PA)remains ***,the apolipoprotein A-I(apoA-I),a PA-modulated lipoprotein,could play a role in this relationship because it shares a binding site with IF1 on the cell-surface ATP *** examined here the associations between chronic PA and plasma IF1 concentrations among older adults,and we investigated whether apoA-I mediated these ***:In the present work,1096 healthy adults(63.8%females)aged 70 years and over who were involved in the multidomain Alzheimer Prevention Trial study were ***1 plasma concentrations(square root of ng/mL)were measured at the 1-year visit of the multidomain Alzheimer Prevention Trial,while PA levels(square root of metabolic equivalent task min/week)were assessed using questionnaires administered each year from baseline to the 3-year *** linear regressions were performed to investigate the associations between the first-year mean PA levels and IF1 *** analyses were conducted to examine whether apoA-I mediated these *** linear regressions were carried out to investigate whether the 1-year visit IF1 concentrations predicted subsequent changes in ***:multiple linear regressions indicated that first-year mean PA levels were positively associated with IF1 concentrations(B=0.021;SE=0.010;p=0.043).mediation analyses revealed that about 37.7%of this relationship was mediated by apoA-I(B_(ab)=0.008;SE=0.004;p=0.023).Longitudinal investigations demonstrated that higher concentrations of IF1 at the 1-year visit predicted a faster decline in PA levels over the subsequent 2 years(time×IF1:B=0.148;SE=0.066;p=0.025).Conclusion:This study demonstrates that regular PA is associated with plasma IF1 concentrations,and it suggests that apoA-I partly med

关键词： Aging Apolipoprotein Bioenergetics Exerkine mitochondria

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Effect of drug therapies on self-reported chemosensory outcomes after COVID-19

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 88-96页

作者： marco A.Fornazieri bruno m.Cunha Samuel P.Nicácio Lucas K.Anzolin JoséL.B.da Silva Aristides Fernandes Neto Deusdedit Brandão Neto Richard L.Voegels Fábio D.R.Pinna Department of Surgery Londrina State UniversityLondrinaBrazil Department of medicine Pontifical Catholic University of ParanáLondrinaBrazil Department of Otorhinolaryngology University of São PauloSao PauloBrazil Department of Otorhinolaryngology:Head and Neck Surgery Perelman School of MedicineSmell and Taste CenterUniversity of PennsylvaniaPhiladelphiaPennsylvaniaUSA

Objective:The aim of this study was to assess the relative efficacy of medications used following severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)infection on self-reported alterations in taste and/or smell ***:Seven hundred and fourteen persons with self-reported postcoronavirus disease 2019(post-COVID-19)chemosensory disorders were personally interviewed regarding specific medications they were administered following the acute phase of the *** dependent measure—self-reported total recovery of chemosensory symptoms—was subjected to stepwise logistic *** predictors included demographic and clinical variables,in addition to specific medications used to mitigate disease symptoms(i.e.,systemic corticosteroids,oseltamivir,vitamin C,ibuprofen,hydroxychloroquine,azithromycin,ivermectin,nitazoxanide,anticoagulants,and zinc).Results:The median time between COVID-19 symptom onset and the interviews was 81 days(interquartile range:60-104).Of the 714 subjects,249(34.9%)reported total recovery of their chemosensory function;437(61.2%)had at least one treatment since the beginning of the *** and those with more comorbidities had undergone more *** recovery rates of the treated and nontreated groups did not differ ***,respondents who had used nitazoxanide tended to have a higher rate of self-reported taste or smell *** who took oral zinc were less likely to ***:No medication employed during the first months after SARS-CoV-2 infection had a clear positive effect on returning self-reported smell or taste function to normal,although nitrazoxide trended in a positive *** zinc had a negative effect on the reported recovery of these senses.

关键词： chemosensory disorder coronavirus infections COVID-19 drug therapy SARS-CoV-2 smell loss taste loss

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阿尔茨海默病的药物回顾和展望

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Science Bulletin 2024年第10期69卷 1369-1374页

作者： Davide Angioni Julien Delrieu Nicola Coley Pierre-Jean Ousset Jiong Shi bruno Vellas Institut Hospitalo Universitaire HealthAge Alzheimer’s Disease Research and Clinical CenterToulouse University HospitalToulouse 31000France Center for Epidemiology and Research in Population Health(CERPOP) University of ToulouseINSERM UMR1295UPSToulouse 31000France Department of Epidemiology and Public Health Toulouse University HospitalToulouse 31000France Department of Neurology The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230026China

With population aging,the number of people with dementia is expected to increase over the coming ***’s disease(AD),the leading cause of dementia worldwide,is characterized by a progressive loss of autonomy leading to dramatic consequences for patients and their caregivers,as well as an increase in health and social care *** main physiopathological features of AD include deposition of amyloid plaques and neurofibrillary tau tangles.

关键词：阿尔茨海默病 Alzheimer tau

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