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Environmental sampling of volatile organic compounds during the 2018 Camp Fire in Northern California

Journal of Environmental Sciences 2021年第5期33卷 135-147页

作者： Leslie A.Simms Eva Borras Bradley S.Chew bruno matsui Mitchell M.McCartney Stephen K.Robinson Nicholas Kenyon Cristina E.Davis Department of Mechanical and Aerospace Engineering University of CaliforniaDavisOne Shields Avenue2132 Bainer HallDavisCA 95616USA Institute for Space Research University of CaliforniaDavisOne Shields AvenueDavisCA 95616USA Department of Internal Medicine University of CaliforniaDavis4150V StreetSuite 3400SacramentoCA 95817USA VA Northern California Health Care System 10535 Hospital WayMatherCA 95655USA

Trace analysis of volatile organic compounds(VOCs) during wildfires is imperative for environmental and health risk assessment. The use of gas sampling devices mounted on unmanned aerial vehicles(UAVs) to chemically sample air during wildfires is of great interest because these devices move freely about their environment, allowing for more representative air samples and the ability to sample areas dangerous or unreachable by humans. This work presents chemical data from air samples obtained in Davis, CA during the most destructive wildfire in California's history-the 2018 Camp Fire – as well as the deployment of our sampling device during a controlled experimental fire while fixed to a UAV. The sampling mechanism was an in-house manufactured micro-gas preconcentrator(μPC) embedded onto a compact battery-operated sampler that was returned to the laboratory for chemical analysis. Compounds commonly observed in wildfires were detected during the Camp Fire using gas chromatography mass spectrometry(GC–MS), including BTEX(benzene, toluene, ethylbenzene, m + p-xylene, and o-xylene), benzaldehyde, 1,4-dichlorobenzene, naphthalene, 1,2,3-trimethylbenzene and 1-ethyl-3-methylbenzene. Concentrations of BTEX were calculated and we observed that benzene and toluene were highest with average concentrations of 4.7 and 15.1 μg/m^(3), respectively. Numerous fire-related compounds including BTEX and aldehydes such as octanal and nonanal were detected upon experimental fire ignition, even at a much smaller sampling time compared to samples taken during the Camp Fire. Analysis of the air samples taken both stationary during the Camp Fire and mobile during an experimental fire show the successful operation of our sampler in a fire environment.

关键词： Volatile organic compounds(VOCs) Wildfire 2018 Camp Fire Micro preconcentrators Environmental sampling Mobile VOC sampling

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Single-cell pan-omics, environmental neurology, and artificial intelligence:the time for holistic brain health research

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Neural Regeneration Research 2025年第6期20卷 1703-1704页

作者： Paolo Abondio Francesco bruno IRCCS Istituto delle Scienze Neurologiche di Bologna BolognaItaly Association for Neurogenetic Research(ARN) Lamezia TermeCatanzaroItaly

The brain,with its trillions of neural connections,different cellular types,and molecular complexities,presents a formidable challenge for researchers aiming to comprehend the multifaceted nature of neural *** traditional methods have provided valuable insights,emerging technologies offer unprecedented opportunities to delve deeper into the underpinnings of brain *** the everevolving landscape of neuroscience,the quest to unravel the mysteries of the human brain is bound to take a leap forward thanks to new technological improvements and bold interpretative frameworks.

关键词： function artificial landscape

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Aging men-Challenges ahead

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Asian Journal of Andrology 2001年第3期3卷 161-168页

作者： bruno Lunenfeld Faculty of Life Sciences Bar-Ilan University Israel

The prolongation of life expectancy and the drastic reduction of fertility rate are the primary cause of an agingworld. It is projected that the elderly (above 65) will increase within the next 25 years by 82% , whereas the new bornonly by 3% . Despite the enormous medical progress during the past few decades, the last years of life are still accom-panied by increasing ill health and disability. The ability to maintain active and independent living for as long as possi-ble is a crucial factor for aging in health and dignity. Therefore, the promotion of healthy aging and the prevention ofdisability in men, must assume a central role in medical research and medical practice as well as in the formulation ofnational health and social policies. Effective programs promoting health and aging will ensure a more efficient use ofhealth and social services and improve the quality of life in older persons by enabling them to remain independent andproductive. The most important and drastic gender differences in aging are related to organs and or systems dependantor influenced by reproductive hormones. In distinction to the course of reproductive aging in women, with the rapid de-cline in sex hormones and expressed by the cessation of menses, aging men experience a slow and continuous decline ofhormones. This decline in endocrine function involves; A decrease of testosterone, dehydroepiandrosterone (DHEA),oestrogens, thyroid stimulating hormone (TSH), growth hormone (GH), insulin-like growth factor-1 (IGF-1), andmelatonin. This decrease is concomitant with an increase of LH and FSH. In addition sex hormone binding globulin's(SHBG) increase with age resulting in further lowering the concentrations of free biologically active androgens. Inter-ventions such as hormone replacement therapy may prevent, delay or alleviate the debilitating conditions which may re-sult from secondary partial endocrine deficiency. Primary and secondary preventive strategies such as the promotion of asafe

关键词： aging life expectancy health expectancy fertility HRT(hormone replacement therapy) quality of life preventive strategies

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The advantages of Low Pressure Carburizing in the Heat Treatment Subcontracting Business

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材料热处理学报 2004年第5期25卷 364-369页

作者： Guy PRUNEL bruno STAUDER BODYCOTE Chassieu FranceBODYCOTE Chassieu France

Low Pressure Carburizing (LPC) was introduced in the 90’s in the western Europe Heat Treatment business, mainly for in-house applications where it was especially appreciated for Carburizing of transmission parts. However the success of the LPC units installed for gears Carburizing in the automotive industry has hindered the development of the process in other fields - like subcontracting business -, where its advantages deserve to be enlightened. After a brief review of the principle of the process, the interest of its classical application to transmission parts is described, underlining peculiarly the reduction of the distortion observed when LPC is associated with high pressure gas quenching. Then the less-known advantages of the LPC process, like the high accuracy and reproducibility of the results, the modeling possibility and the simulation easiness, the case-depth uniformity and the full flexibility of the units are considered, showing how they can be beneficial to subcontracting business.

关键词：低压渗碳热处理转包商业 LPC 应用

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Birds caught in spider webs in Asia

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Chinese Birds 2016年第3期7卷 180-186页

作者： bruno A.Walther Master Program in Global Health and Development College of Public Health Taipei Medical University

A recent global review of birds caught in spider webs reported only three Asian cases. Given this surprisingly low number, I made a concerted effort to obtain additional Asian cases from the literature, the internet, and field workers. I present a total of 56 Asian cases which pertain to 33 bird species. As in the global dataset, mostly small bird species were caught in spider webs, with a mean body mass of 17.5 g and a mean wing chord length of 73.1 mm. Conse?quently, birds with a body mass >30 g were very rarely caught. This Asian review corroborates the global review that smaller birds are more likely to be caught and that Nephila spiders are most likely to be the predators. Continuous monitoring of spider webs is recommended to ascertain the frequency of these events.

关键词： Spider Predator–prey relationships Asia

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Stage migration vs immunology: The lymph node count story in colon cancer

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World Journal of Gastroenterology 2015年第43期21卷 12218-12233页

作者： bruno Markl Institute of Pathology Klinikum Augsburg86156 AugsburgGermany

Lymph node staging is of crucial importance for the therapy stratification and prognosis estimation in colon cancer. Beside the detection of metastases,the number of harvested lymph nodes itself has prognostic relevance in stage Ⅱ/Ⅲ cancers. A stage migration effect caused by missed lymph node metastases has been postulated as most likely explanation for that. In order to avoid false negative node staging reporting of at least 12 lymph nodes is recommended. However,this threshold is met only in a minority of cases in daily practice. Due to quality initiatives the situation has improved in the past. This,however,had no influence on staging in several studies. While the numbers of evaluated lymph nodes increased continuously during the last decades the rate of node positive cases remained relatively constant. This fact together with other indications raised doubts that understaging is indeed the correct explanation for the prognostic impact of lymph node harvest. Several authors assume that immune response could play a major role in this context influencing both the lymph node detectability and the tumor's behavior. Further studies addressing this issue are need. Based on the findings the recommendations concerning minimal lymph node numbers and adjuvant chemotherapy should be reconsidered.

关键词： Colon cancer Lymph node harvest Stage migration Understaging Will Rogers Immune response

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Analysis of a malaria model with mosquito host choice and bed-net control

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International Journal of Biomathematics 2015年第6期8卷 119-140页

作者： bruno Buonomo Department of Mathematics and Applications University of Naples Federico H via Cintia 1-80126 Naples Italy

A malaria model is formulated which includes the enhanced attractiveness of infectious humans to mosquitoes, as result of host manipulation by malaria parasite, and the human behavior, represented by insecticidetreated bed-nets usage. The occurrence of a backward bifurcation at R0 = 1 is shown to be possible, which implies that multiple endemic equilibria co-exist with a stable disease-free equilibrium when the basic repro- duction number is less than unity. This phenomenon is found to be caused by disease- induced human mortality. The global asymptotic stability of the endemic equilibrium for R0 〉1 is proved, by using the geometric method for global stability. Therefore, the disease becomes endemic for R0〉 1 regardless of the number of initial cases in both the human and vector populations. Finally, the impact on system dynamics of vector＇s host preferences and bed-net usage behavior is investigated.

关键词： Malaria backward bifurcation global stability vector's host preference human behavior.

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Key drivers of ecosystem recovery after disturbance in a neotropical forest Long-term lessons from the Paracou experiment, French Guiana

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Forest Ecosystems 2018年第1期5卷 13-27页

作者： bruno hérault camille piponiot cirad umr ecofog (agro paristech cnrs inra université des antillesuniversité de la guyane) campus agronomique97310 kouroufrench inphb (institut national polytechnique félix houphouet boigny) yamoussoukroivorycoast université de la guyane umrecofog(agro paristech cirad cnrs inra université des antilles) campus agronomique97310 kouroufrench guianafrance

Background： Natural disturbance is a fundamental component of the functioning of tropical rainforests let to natural dynamics, with tree mortality the driving force of forest renewal. With ongoing global （i.e. land-use and climate） changes, tropical forests are currently facing deep and rapid modifications in disturbance regimes that may hamper their recovering capacity so that developing robust predictive model able to predict ecosystem resilience and recovery becomes of primary importance for decision-making：（i） Do regenerating forests recover faster than mature forests given the same level of disturbance？（ii） is the local topography an important predictor of the post-disturbance forest trajectories？（iii） Is the community functional composition, assessed with community weighted-mean functional traits, a good predictor of carbon stock recovery？（iv） How important is the climate stress （seasonal drought and/or soil water saturation） in shaping the recovery trajectory？ Methods： Paracou is a large scale forest disturbance experiment set up in 1984 with nine 6.25 ha plots spanning on a large disturbance gradient where 15 to 60% of the initial forest ecosystem biomass were removed. More than 70,000 trees belonging to ca. 700 tree species have then been censused every 2 years up today. Using this unique dataset, we aim at deciphering the endogenous （forest structure and composition） and exogenous （local environment and climate stress） drivers of ecosystem recovery in time. To do so, we disentangle carbon recovery into demographic processes （recruitment, growth, mortality fluxes） and cohorts （recruited trees, survivors）. Results： Variations in the pre-disturbance forest structure or in local environment do not shape significantly the ecosystem recovery rates. Variations in the pre-disturbance forest composition and in the post-disturbance climate significantly change the forest recovery trajectory. Pioneer-rich forests have slower recovery rates than assemblages of lat

关键词： Ecosystem modeling Tropical forests Carbon fluxes Ecological resilience Climate change Amazonia

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Doubling down with CAR-T cell cancer immunotherapy:a two-step recognition circuit enables discrimination between target antigen high and low cancer cells

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Signal Transduction and Targeted Therapy 2021年第8期6卷 2280-2281页

作者： Jehad Charo bruno Gomes hoffmann-la roche ag pharmaceutical research and early development oncologyroche innovation center zurichzurichswitzerland hoffmann-la roche ag pharmaceutical research and early development oncologyroche innovation center baselbaselswitzerland

In a recent article published in Science by Hernandez-Lopez et *** antigen receptor(CAR)expressing T(CAR-T)cells with a two-step recognition system successfully discriminated between target cells expressing high and l... 详细信息

关键词： CAR cancer

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Persistent X-ray-activated phosphors:mechanisms and applications

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Light(Science & Applications) 2022年第6期11卷 1008-1010页

作者： Cyrille Richard bruno Viana UniversitéParis Cité CNRSINSERMUTCBSUnitéde Technologies Chimiques et Biologiques pour la SantéFacultéde Pharmacie75006 ParisFrance IRCP CNRS UMR8247PSL UniversityChimie ParisTech11 Rue P&M Curie75005 ParisFrance

Trivalent lanthanides in wide bandgap fluoride or phosphate hosts can present persistent luminescence between 200 nm and 1.7 μm after charging by *** are reviewed and applications envisioned.

关键词： lanthanide fluoride luminescence

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