检索结果-南通市图书馆

Obesity in people with diabetes in COVID-19 times: Important considerations and precautions to be taken

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2021年第20期9卷 5358-5371页

作者： Adriano Alberti Fabiana Schuelter-Trevisol Betine Pinto Moehlecke Iser Eliane Traebert Viviane Freiberger Leticia Ventura Gislaine Tezza Rezin bruna Becker da Silva Fabiana Meneghetti Dallacosta Leoberto Grigollo paula Dias Gracielle Fin Josiane Aparecida de Jesus Fabiane Pertille Carina Rossoni Ben Hur Soares Rudy JoséNodari Júnior Clarissa Martinelli Comim Research Group in Neurodevelopment of Childhood and Adolescence Laboratory of Experimental NeurosciencePostgraduate Program in Health SciencesUniversity of South Santa Catarina(Unisul)Palhoça88137-270Santa CatarinaBrazil Brazil Clinical Research Center Postgraduate Program in Health SciencesUniversity of Southern Santa Catarina at TubarãoTubarão88704-900Santa CatarinaBrazil Postgraduate Programme in Health Sciences University of Southern Santa CatarinaPalhoça88137-270Santa CatarinaBrazil Postgraduate Program in Biosciences and Health University of the West of Santa CatarinaJoaçaba89600-000Santa CatarinaBrazil department of Physical Education University of the West of Santa CatarinaJoaçaba89600-000Santa CatarinaBrazil Environmental Health Institute of the Faculty of Medicine of the University of Lisbon Lisboa1649-029Portugal Health Science University of Passo FundoPasso Fundo99052-900Rio Grande do SulBrazil Research department Salus DermatoglifiaLuzerna89609-000Santa CatarinaBrazil

At the end of 2019,a new disease with pandemic potential appeared in *** was a novel coronavirus called coronavirus disease 2019(COVID-19).Later,in the first quarter of 2020,the World Health Organization declared the outbreak of this disease a *** people,people with comorbidities,and health care professionals are more vulnerable to *** has been growing exponentially worldwide,affecting several age *** is a morbidity that is associated with genetic,epigenetic,environment factors and/or interaction between *** is associated with the development of several diseases including diabetes mellitus,mainly type *** affects a significant portion of the global *** and diabetes are among the main risk factors for the development of severe symptoms of COVID-19,and individuals with these conditions constitute a risk *** on a literature review on obesity in people with diabetes in the framework of the COVID-19 pandemic,this study presents updated important considerations and care to be taken with this population.

关键词： Obesity Diabetes COVID-19 Population World Disease

Characteristics of Mesenchymal Stem Cells under Hypoxia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CellBio 2013年第1期2卷 11-19页

作者： bruna Amorin Ana paula Alegretti Vanessa de Souza Valim Annelise Martins Pezzi da Silva Maria Aparecida Lima da Silva Felipe Sehn Lucia Silla Cell Technology Center Experimental Research Center Hospital de Clínicas de Porto Alegre-Porto AlegreRio Grande do Sul Brazil

Mesenchymal stem cells (MSC) are considered non-hematopoietic multipotent stem cells with self-renewal properties and the ability to differentiate into a variety of mesenchymal tissues. Optimal conditions for the culture of these cells have been the subject of investigation for several years. In particular, ideal oxygen tension levels have not been established in the literature. In physiological environments, oxygen tension may vary from 12% in peripheral blood to 1% in the deep zone of cartilage regions. In any case, oxygen tension is considerably lower in vivo when compared with the normal atmosphere of standard cell culture conditions (21%). The objective of this study was to review the literature available on MSC characteristics (cell cycle, survival, proliferation, differentiation, morphology, immunophenotype, cytogenetics) when cultured under hypoxic conditions. Our focus on optimal culture conditions is justified by the key role currently played by these cells in regenerative medicine.

关键词： Mesenchymal Stem Cells Culture Hypoxia

Optimization of the Cultivation of Donor Mesenchymal Stromal Cells for Clinical Use in Cellular Therapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CellBio 2014年第1期3卷 25-33页

作者： Vanessa Valim bruna Amorin Annelise Pezzi Maria Aparecida Lima da Silva Ana paula Alegretti Lucia Silla Cellular Therapy Center Hospital de Clinicas de Porto Alegre Porto Alegre Brazil Post-Graduation in Medicine: Medical Sciences Federal University of Rio Grande do Sul Porto Alegre Brazil Cellular Therapy Center Hospital de Clinicas de Porto Alegre Porto Alegre Brazil Post-Graduation in Medicine: Medical Sciences Federal University of Rio Grande do Sul Porto Alegre Brazil Hematology and Bone Marrow Transplantation Hospital de Clinicas de Porto Alegre Porto Alegre Brazil

Mesenchymal stromal cells(MSC)have shown their benefits in graft-versus-host disease(GVHD), with five unsettled matters: 1) MSCs expansion in medium with Fetal Bovine Serum(FBS)and its risk of xenoreaction;2) The number of cells indicated for therapy that is relatively high, with the need to optimize the expansion, number and time wise;3) The utilization of third party donors;4) Culture passage number(P);and 5) Source of the cells. This study was designed to determine the superiority of the Platelet Lysates(PL)over FBS on the expansion of MSC, the optimal cell’ plating density and days between each pass, and to investigate if donor total nucleated cells(TNC)obtained from the washouts of discharged bags and filters of hematopoietic stem cell transplantation(HSCT)can be expanded to be used at clinical grade. TNC were removed, plated and after the first passage were cultivated in different concentrations with FBS or PL, and the number of days to reach 80% of confluence was observed. Next, cultures with the same plating density were fed either with PL or with FBS and after seven days counted to analyze how much they had grown in that period. The proliferation of mesenchymal stromal cells in the presence of PL and SFB was averaged 11.88 and 2.5 times, respectively, in a period of 7 days. The highest concentration of plating cells using PL took less time to reach confluence as compared with the three lower ones. This study suggests that the PL is the best choice as a supplement to expand MSC and to allow the proliferation of enough number of MSC at P2 for clinical use.

关键词： Platelet Lysate MSC Optimization Cell Therapy

Comparison of Functional Capability,Flexibility,Strength and Quality of Life in Aged Women Engaged in Resistance Exercise,Weight-Bearing Training or Hydro-Gymnastics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Sports Science 2019年第4期7卷 106-114页

作者： Otávio Augusto Soares Machado Waldecir paula Lima bruna Vieira de Souza Fábio Gianolla Luiz Francisco Killian Giovanna Athanásio Chaves Machado Renata Gorjao Physiology and Metabolism Research Center YMCA Physical Education FacultySorocaba-SPBrazil Federal Institute of Education Science and TechnologySao Paulo-SPBrazil Postgraduate Program in Interdisciplinary Health Science Cruzeiro do Sul UniversitySao Paulo-SPBrazil

Although any type or amount of physical exercise may reverse the cellular processes that lead to the aging,regular physical exercise can attenuate the decline in physical and functional abilities observed in ***,the most encouraged activities in gyms and clubs are resistance training,functional training,and *** main objective of this study was to compare the effects of the aforementioned exercises regarding muscle strength,flexibility,functional capability and quality of life of elderly *** divided 36 elderly women in four groups:Sedentary(S);Hydro-gymnastics(H);Functional Training(F);or Resistance Training(RT).The results reveal that the groups engaged in physical exercise showed a significant difference(p<0.05)in relation to S in all *** results also show that between the different exercises evaluated,resistance training practitioners have greater strength and better functional capability.

关键词： Aged exercise physical fitness quality of life

Palm Red Mite Management with Soursop Seed Plant Residue Extracts

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Agricultural Sciences 2023年第4期14卷 541-552页

作者： Ana Beatriz Mamedes Piffer Evellyn Zuqui Bolsoni Isabella Merlo Fornaciari Anderson Mathias Holtz Johnatan Jair de paula Marchiori Jose Romário de Carvalho Ronilda Lana Aguiar Patrícia Soares Furno Fontes bruna de Oliveira Magnani Campus Itapina Federal Institute of Espírito Santo Colatina Brazil Campus Seropédica Federal University Rural of Rio de Janeiro Seropédica Brazil Secretary of State for Education of Espírito Santo Gua&#231uí Brazil

Raoiella indica Hirst, 1924 (Prostigmata: Tenuipalpidae), is one of the leading pest mites in palm and banana trees, however, there are few control methods available for this pest species. Therefore, this work aimed to evaluate the acaricidal effect of soursop seed extract (Annona muricata L.) on R. indica adults. The experiment was conducted in a completely randomized design using soursop seed extract with 7 replicates and 12 individuals of R. indica per replicate. The experimental units consisted of discs of coconut palm leaves (4 cm in diameter), with cotton moistened at the bottom of the Petri dish (10.0 × 1.2 cm) and around the disc to maintain turgor and prevent mites from escaping. The application was performed using an airbrush, connected to a calibrated compressor with a constant pressure of 1.3 psi and 1 mL of solution per repeat plate. The acaricidal effect was evaluated 24, 48, and 72 hours after spraying. Mortality data were corrected and submitted to Probit analysis (p ≤ 0.05) using the statistical program R, with the LC50 and LC90 calculated for the extract. At the maximum concentration (15%), the soursop seed extract showed mortality of 70% of individuals of R. indica, and the LC50 was 6.58%. It was concluded that the soursop seed extract showed acaricidal potential on R. indica in the laboratory.

关键词： Annona muricata Raoiella indica Alternative Control Agro-Industrial Residue

Revealing the kinetics of Leishmania chagasi infection in the male genital system of hamsters

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Infectious Diseases of Poverty 2016年第1期5卷 261-265页

作者： Amanda P.N.Quintal bruna C.Borges paula C.Brígido Rebecca T.Silva Ana F.Notário Marlus A.Santos Maria A.de Souza Fernanda G.O.Nascimento Antônio V.Mundim Guilherme M.J.Costa André B.Vasconcelos Claudio V.da Silva Instituto de Ciências Biomédicas Universidade Federal de UberlândiaUberlândiaMinas GeraisBrasil Hospital Veterinário Universidade Federal de UberlândiaUberlândiaMinas GeraisBrasil departamento de Ciências Biomédicas Universidade Federal de Minas GeraisBelo HorizonteBrasil Universidade de Uberaba UberabaMinas GeraisBrasil departamento de Imunologia–Instituto de Ciências Biomédicas Universidade Federal de UberlândiaCampus UmuaramaUberlândiaMGBrasil

Background:Leishmaniasis causes alterations and lesions in the genital system,which leads to azoospermia and testicular atrophy in animals during the chronic phase of the *** aim of this study was to reveal the kinetics of Leishmania chagasi infection in the genital system of male golden hamsters(Mesocricetus auratus).Methods:Animals were intraperitoneally inoculated with amastigotes from *** different time points animals were euthanized and genital organs processed for histo-pathological,qPCR,cytokines and testosterone detection ***:Our results showed a high parasite load in testis,followed by an increase of pro-inflammatory cytokines IL1-β,TNF-αand IFN-γ,and ***,IL-4 expression was upregulated and basal parasite persistence in testis was observed using the experimental ***:Extracellular amastigotes migrated to the epididymis posing as a potential major factor of parasite persistence and venereal transmission of *** infection in hamsters.

关键词： Leishmania chagasi Extracellular amastigotes Testis Epididymis Immune response Testosterone

Punica granatum Leaf Lipophilic Fraction Favours Mortality by Attenuating Inflammation in Mice with Polymicrobial Sepsis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Pharmacy and Pharmacology 2019年第7期7卷 355-367页

作者： Nagila Caroline Fialho sousa Isabella Fernandes da Silva Figueiredo Mizael Calacio de Araujo Elaine Pereira de Andrade Thais Costa alves bruna Letícia Rosa da Silva Domingos Magno Santos Pereira Saulo JoseFigueiredo Mendes Joao Francisco Silva Rodrigues Jaqueline Pessoa Pontes Simone Aparecida Teixeira AndreAlvares Marques Vale Marcus Vinicius Dias-Souza Lidio goncalves Lima-Neto Vera Lucia dos Santos Ana paula Azevedo-Santos Marcelo Nicolas Muscara Valerio Monteiro-Neto Andrea de Souza Monteiro Luis Claudio Nascimento da Silva Elizabeth Soares Fernandes Programa de Pos-graduacao Universidade CEUMARua JosueMontellon°1RenascencaSao LuisMA 65075-120Brazil departamento de Farmacologia Universidade de Sao PauloAv.Prof.Lineu Prestesn°1524Sala 326ButantanSao PauloSP 05508-900Brazil Programa de Pos-graduacao em Ciências em Saude Universidade Federal do MaranhaoAvenida dos Portuguesesn°1966BacangaSao LuisMA 65080-805Brazil departamento de Microbiologia Universidade Federal de Minas GeraisAv.Antonio Carlosn°6627PampulhaBelo HorizonteMG 31270-901Brazil departamento de Patologia Universidade Federal do MaranhaoAvenida dos Portuguesesn°1966BacangaSao LuísMA 65080-805Brazil

Punica granatum *** known antimicrobial and anti-inflammatory *** of different parts of this plant have been commonly used in the folk medicine to prevent and treat infections;and studies have supported the use of *** extracts for this ***,little is known of the effects of ***-derived fractions in severe infectious diseases such as ***,we investigated the actions of the hexane fraction(HF),rich in lipophilic compounds,obtained from the leaves of this plant,in a murine model of polymicrobial *** pre-treatment with HF increased mortality in septic *** same animals presented with lower levels of interleukin-6,nitric oxide and hydrogen peroxide in their peritoneal lavage samples than vehicle *** also increased polymorphonuclear cell accumulation in to the peritoneum of mice with ***-derived nitric oxide upon lipopolysaccharide stimuli was markedly reduced by incubation with ***,triterpenes,phytosterols,vitamin E and ascorbyl palmitate were detected in the *** results indicate that *** leaf lipophilic fractions may worsen sepsis *** effect may be associated with its bioactive compounds which act synergistically or not,increasing sepsis mortality in vivo.

关键词： P.granatum infection inflammation

Contributions on Selective Waste Collection and Recycling Cooperatives in Municipalities in the State of São Paulo,Brazil

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Science and Engineering(B) 2022年第5期11卷 189-205页

作者： Clauciana Schmidt Bueno de Moraes Larissa Senden Carnicel Adriana Maria Nolasco Giulia Malaguti Braghini Marcolini Martires Cinthia Mara Vital Bonaretto Willian Leandro Henrique Pinto bruna Ferrari Felipe Felipe JoséSasso Laís Araújo de paula São Paulo State University(UNESP) São Paulo 13506-900Brazil School of Technology University of Campinas(UNICAMP)Limeira 13484-332Brazil University of São Paulo(USP) 13.418-900.PiracicabaBrazil Fehily Timoney and Company D11 PXT0.DublinIreland

The collection and proper disposal of MSW(Municipal Solid Waste)is one of the biggest challenges faced by Brazilian public *** recyclable waste represents about 33.6%of the gravimetric composition of MSW,with a tendency to increase in the next few years,due to the increasing consumption of processed products,with short life cycles and excess *** inadequate management of these residues results in a series of social,environmental and economic *** recent years,there has been a great advance in Brazilian laws,assigning responsibilities and regulating waste management in the country,optimizing the use of infrastructure and human and financial *** resources and insufficient infrastructure demand actions based on a lot of *** of the main limiting factors for the planning and development of public policies for the sector is the lack of reliable data and information on the generation and management of waste,that allow the creation of future scenarios and the definition of adequate strategies for minimization,valorization of waste and final disposal of waste that no longer can be ***,this work sought to analyze the current situation of selective waste collection and recycling cooperatives in 211 municipalities in the State of São Paulo,evaluating the issues and opportunities for the applicability of Law n.12,305/2010,Brazilian PNRS(in Portuguese)(National Policy of Solid Waste)in the management of this waste in small,medium and large cities.A bibliographic research was carried out on the panorama of solid waste management in Brazil and in the State of São Paulo,as well as a contextualization on selective waste collection and recycling *** that,data from 211 municipalities taking part in the survey Solid Waste Management—Municipalities of the State of São Paulo were analyzed,focusing on answers that correlated with the topics covered in this *** this work,questions were used in order to obt

关键词： Solid waste Brazilian National Policy of Solid Waste solid waste management MSW recycling cooperatives

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

一种源自皮肤护理灵感的发丝保湿技术

中国化妆品 2022年第11期 76-79页

作者： Cartaxo Rita Nakatu bruna Lourenco Carolina Gasparin Rebeca paula Marcia 不详

干燥的头发需要护理和修复以恢复其保湿性和健康的外观,但头发的保湿作用是通过除了水含量之外的功效来感知的。Hydroviton Hair馨丝润可在头发纤维.上发挥成膜性使其变得光滑,改善湿发和干发的可梳理性,提升头发柔软度,使毛鳞片的整体... 详细信息

干燥的头发需要护理和修复以恢复其保湿性和健康的外观,但头发的保湿作用是通过除了水含量之外的功效来感知的。Hydroviton Hair馨丝润可在头发纤维.上发挥成膜性使其变得光滑,改善湿发和干发的可梳理性,提升头发柔软度,使毛鳞片的整体排列有序,并通过重新平衡静电荷来有效控制头发体积和毛糙。

关键词：静电荷皮肤护理保湿性保湿作用柔软度头发纤维成膜性保湿技术