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预测体外膜式氧合器支持治疗非早产儿急性缺氧性呼吸衰竭的预后状况

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世界核心医学期刊文摘（儿科学分册） 2005年第2期1卷 23-24页

作者： brown k.l. Walker S. Grant D.J. A.P.Goldman 张振 Dr.Cardiac Intensive Care UnitGt.Ormond St.Hosp.Children NHS T. London WC1N 3JHUnited Kingdom

目的:体外膜式氧合(ECMO)支持技术,可用于治疗非早产儿发生的急性缺氧性呼吸衰竭;本文着眼于确定可用于反映此类患儿预后状况的预测指标。方法:以1992-2001年间在英国出生的、发生了获得性急性缺氧性呼吸衰竭的、并进行体外膜式氧合支... 详细信息

目的:体外膜式氧合(ECMO)支持技术,可用于治疗非早产儿发生的急性缺氧性呼吸衰竭;本文着眼于确定可用于反映此类患儿预后状况的预测指标。方法:以1992-2001年间在英国出生的、发生了获得性急性缺氧性呼吸衰竭的、并进行体外膜式氧合支持治疗的非早产儿作为研究对象;搜集其病例资料。

关键词：体外膜式氧合器支持治疗呼吸衰竭呼吸道合胞病毒诊疗措施年龄中位数全科医师专科医师随访调查妊娠时间

Cool white light and tunable multicolor emission from Tb^(3+)/Dy^(3+)co-activated glasses under different excitations for WlEDs

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Journal of Rare Earths 2024年第1期42卷 46-56,I0002页

作者： l.Vijayalakshmi k.Naveen kumar Jong Dae Baek Department of Automotive Engineering Yeungnam UniversityGyeongsanGyeongbuk38541Republic of Korea Department of Mechanical Engineering Yeungnam UniversityGyeongsan38541Republic of Korea

A set of co-doped(Tb^(3+)/Dy^(3+))lithium zinc borate(lZB)glasses were developed by melt *** structural evaluation was performed for synthesized glassy *** Dy^(3+)and Tb^(3+)individually doped glasses exhibit intense yellow and green luminescence bands at 575 nm(^(4)F_(9/2)→^(6)H_(13/2))and543 nm(^(5)D_(4)→^(7)F_(5)),*** sensitization effect of Dy^(3+)on Tb^(3+)was analyzed by increasing the Tb^(3+)content with respect to the optimum Dy^(3+)content(0.5 mol%)in Dy^(3+)/Tb^(3+).The spectral overlay of Dy^(3+)luminescence and Tb^(3+)absorption profiles,Dy^(3+)/Tb^(3+)Pl spectra under different excitations 352,362,376,and 385 nm,shortening decay lifetimes of Dy^(3+)in Dy^(3+)/Tb^(3+)co-activated glasses,energy transfer(ET)parameters,chromaticity coordinates and their corresponding correlated temperatures all help to explain ET from Dy^(3+)to Tb^(3+).At 385 nm of Dy^(3+)excitation,the optimized co-activated(0.5Dy^(3+)+1.0Tb^(3+)):lZB glass displays cool white light *** non-radiative ET from Dy^(3+)to Tb^(3+)is dominated by electric dipole-dipole interaction and its ET efficiency was calculated to be 63%.At the same time,reverse ET from Tb^(3+)to Dy^(3+)was also *** shift in color coordinates from dominant yellow to greenish-yellow,green and white light emission suggests that Dy^(3+)/Tb^(3+)coactivated lZB glasses can be a potential candidate for UV converted multicolor and white light emitting devices.

关键词： Rare earths Photoluminescence Energy transfer Spectral overlap Decay lifetime Multicolor emitting lEDs

Effect of cylinder wall parameters on the final packing density of mono-disperse spheres subject to three-dimensional vibrations Author links open overlay panel

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Particuology 2024年第8期91卷 211-225页

作者： Jack R.Grogan Andrei l.Nicuşan Christopher R.k.Windows-Yule School of Chemical Engineering The University of BirminghamEdgbastonBirminghamB152TTUK

Achieving densely packed particles is desirable within the industries of ceramics,pharmaceuticals,defence and additive *** this work,we use the discrete element method(DEM)to determine the effect of wall parameters on the final packing density of mono-disperse spheres subject to 4 varying three-dimensional vibration and fill *** focus specifically on the impact of the container wall parameters on the particles'final packing *** on from the validation of the DEM simulation the particle-wall coefficient of restitution,the particle-wall coefficient of rolling friction and the particle-wall coefficient of sliding friction were varied individually and the effect on the final packing density *** relatively low particle-particle friction glass beads,the effect of these wall properties had no discernible effect on the final packing density *** on from these findings the particle-wall properties were varied at the extreme values of particle-particle coefficient of rolling friction and particle-particle coefficient of sliding *** a particle-particle coefficient of sliding friction=1,increases in particle-wall coefficient of restitution resulted in a minor increase in the final packing density of particles though this was not statistically *** a particle-particle coefficient of sliding friction=1,increases in particle-wall coefficient of rolling friction resulted in a minor decrease in the final packing density of the particles though again not to a degree where the trend can,with complete certainty,be distinguished from the random error across the ***,when the particle-particle coefficient of sliding friction=1,increases in particle-wall coefficient of sliding friction resulted in a significant decrease in the final packing density of *** decrease was attributed to the propagation of force chains throughout the *** significant decrease in final packing density with

关键词： Vibropacking Packing Densification Vibration Discrete element method Friction Wall friction Restitution

Use of donepezil for neurocognitive recovery after brain injury in adult and pediatric populations:a scoping review

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Neural Regeneration Research 2024年第8期19卷 1686-1695页

作者： Avery l.Miller Nathan k.Evanson J.Michael Taylor University of Cincinnati College of Medicine CincinnatiOHUSA Department of Pediatrics University of CincinnatiCincinnatiOHUSA Department of Neurology and Rehabilitation Medicine University of CincinnatiCincinnatiOHUSA Division of Pediatric Rehabilitation Medicine Cincinnati Children’s Hospital Medical CenterCincinnatiOHUSA Division of Neurology Cincinnati Children’s Hospital Medical CenterCincinnatiOHUSA

There are few pharmacologic options for the treatment of cognitive deficits associated with traumatic brain injury in pediatric *** inhibitors such as donepezil have been evaluated in adult patients after traumatic brain injury,but relatively less is known about the effect in pediatric *** goal of this review is to identify knowledge gaps in the efficacy and safety of acetylcholinesterase inhibito rs as a potential a djuvant treatment fo r neurocognitive decline in pediatric patients with traumatic brain *** queried PubMed to identify literature published from database inception thro ugh June 2023 desc ribing the use of donepezil in young adult traumatic brain injury and pediatric patients with predefined *** on preselected search criteria,340 unique papers we re selected for title and abstra ct ***-two reco rds were reviewed in full after eliminating preclinical studies and pape rs outside the scope of the *** adult traumatic brain injury,we review results from 14 papers detailing 227 subjects where evidence suggests donepezil is well tole rated and shows both objective and patient-reported efficacy for reducing cognitive *** children,3 pape rs report on 5 children recovering from traumatic brain injury,showing limited *** additional 15 pediatric studies conducted in populations at risk for cognitive dysfunction provide a broader look at safety and efficacy in 210 patients in the pediatric age *** its promise for efficacy in adults with traumatic brain injury and tole rability in pediatric patients,we believe further study of donepezil for children and adolescents with traumatic brain injury is warranted.

关键词： acetylcholinesterase inhibitor adult cognition donepezil pediatrics traumatic brain injury

SARS-CoV-2 and innate immunity:the good,the bad,and the"goldilocks"

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Cellular & Molecular Immunology 2024年第2期21卷 171-183页

作者： Benjamin l.Sievers Mark T.k.Cheng kata Csiba Bo Meng Ravindra k.Gupta Department of Medicine University of CambridgeCambridgeUK Cambridge Institute of Therapeutic Immunology&Infectious Disease(CITID) Department of MedicineUniversity of CambridgeCambridgeUk

An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of *** about this interplay can not only help us identify biological mechanisms but also reveal pathogen vulnerabilities that can be leveraged *** humoral response to SARS-CoV-2 infection has been the focus of intense research,and the role of the innate immune system has received significantly less ***,we review current knowledge of the innate immune response to SARS-CoV-2 infection and the various means SARS-CoV-2 employs to evade innate defense *** also consider the role of innate immunity in SARS-CoV-2 vaccines and in the phenomenon of long COVID.

关键词： SARS-CoV-2 Innate immune response Interferon Cytokines Inflammation Antiviral targets

Pancreatic surgery and tertiary pancreatitis services warrant provision for support from a specialist diabetes team

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World Journal of Diabetes 2024年第4期15卷 598-605页

作者： Vasileios k Mavroeidis Jennifer knapton Francesca Saffioti Daniel l Morganstein Department of HPB Surgery Bristol Royal InfirmaryUniversity Hospitals Bristol and Weston NHS Foundation TrustBristol BS28HWUnited Kingdom Department of Gastrointestinal Surgery Southmead HospitalNorth Bristol NHS TrustBristol BS105NBUnited Kingdom Department of Academic Surgery Royal Marsden NHS Foundation TrustLondon SW36JJUnited Kingdom Department of Gastroenterology and Hepatology Oxford University Hospitals NHS Foundation TrustOxford OX39DUUnited Kingdom UCl Institute for liver and Digestive Health University College LondonLondon NW32PFUnited Kingdom Department of Endocrinology Chelsea and Westminster Hospital NHS Foundation TrustLondon SW109NHUnited Kingdom Department of Gastrointestinal Unit Royal Marsden NHS Foundation TrustLondon SW36JJUnited Kingdom

Pancreatic surgery units undertake several complex operations,albeit with consi-derable morbidity and mortality,as is the case for the management of complicated acute pancreatitis or chronic *** centralisation of pancreatic surgery services,with the development of designated large-volume centres,has contribu-ted to significantly improved *** this editorial,we discuss the complex associations between diabetes mellitus(DM)and pancreatic/periampullary disease in the context of pancreatic surgery and overall management of complex pancreatitis,highlighting the consequential needs and the indispensable role of specialist diabetes teams in support of tertiary pancreatic *** 3c pan-creatogenic DM,refers to DM developing in the setting of exocrine pancreatic disease,and its identification and management can be challenging,while the glycaemic control of such patients may affect their course of treatment and *** preoperative diabetes assessment is warranted to aid identification of patients who are lik.l. to need commencement or escalation of glucose lowering therapy in the postoperative *** incidence of new onset diabetes after pancreatic resection is widely variable in the literature,and depends on the type and extent of pancreatic resection,as is the case with pancreatic parenchymal loss in the context of severe *** involvement of a specialist diabetes team is essential to ensure a holistic *** the current era,large volume pancreatic surgery services commonly abide by the principles of enhanced recovery after surgery,with inclusion of provisions for optimisation of the perioperative glycaemic control,to improve *** various guidelines are available to aid perioperative management of DM,auditing and quality improvement platforms have highlighted deficiencies in the perioperative management of diabetic patients and areas of required *** need for perioperative support of diabetic

关键词： Pancreatectomy Pancreatoduodenectomy Whipple’s Pancreatitis Diabetes specialist Type 3c pancreatogenic diabetes mellitus

Protection of steel hooks embedded in glass-fiber-reinforced concrete against macrocell corrosion

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Petroleum Research 2024年第2期9卷 317-326页

作者： Husnu Gerengi Muhammed Maraşlı Marziya Rizvi Beni kohen Ismail Taşkıran Corrosion Research laboratory Department of Mechanical EngineeringDuzce University81620DuzceTurkey Department of Engineering and Applied Sciences University of BergamoBGItaly Fibrobeton Company R&D Center DuzceTurkey Department of Chemistry Babasaheb Bhimrao Ambedkar UniversityLucknow226003U.PIndia

This study evaluated the corrosion behavior of steel hooks embedded in GFRC,which were protected by a zinc-rich(96%Zn)galvanizing *** coating provided the hooks with active cathodic protection and a passive physical *** corrosion may form when the anode is smaller than the total steel ***,the steel hooks at the embedment juncture were additionally sealed against water ingress and air exchange using a construction *** study was conducted in three phases in a salt-spray ***,the electrogalvanized steel hooks embedded in GFRC were allowed to freely corrode for 7 *** the second phase,the electrogalvanized steel hooks were painted with the zinc-rich coating and observed over 7 *** the third phase,the steel hooks were protected by the zinc-rich coating together with a primer and construction sealant,and observed over 7 *** evaluate the electrogalvanized hooks and the corrosion products formed,the thickness of the material was *** on the metal surface was inferred by studying the surface morphology of the hooks at various points of contact and after different periods of time.

关键词： Steel rebars Concrete corrosion GFRC Galvanization Sealant

A hybrid solar-biogas system for post-COVID-19 rural energy access

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Clean Energy 2024年第1期8卷 84-99页

作者： Ochuko k.Overen keChrist Obileke Edson l Meyer Golden Makaka Oliver O.Apeh Fort Hare Institute of Technology University of Fort HarePrivate Bag X1314Alice 5700South Africa Department of Physics Renewable Energy Research CentreUniversity of Fort HarePrivate Bag X1314Alice 5700South Africa Department of Electrical and Electronic Engineering Science Faculty of Engineering and Build EnvironmentUniversity of JohannesburgAuckland Park 2006South Africa

Solar home systems for rural electrification are often designed with a limited energy supply,which presents a drawback for the ***,uncontrolled livestock faeces in rural communities constitute environmental sanitation and health *** excrement can be used through a biogas digester to supplement solar energy to provide adequate and sustainable elec-tricity access to underserved rural communities while achieving waste ***,this study presents a hybrid solar-biogas system for a more dynamic energy supply and waste management for post-Covid recovery plans in rural communities.A parametric research approach that involves the use of the Integrated Environment Solution Virtual Environment software application and mathematical models to design the desired household load and the hybrid system sizing is used in the *** findings show that the daily household energy consumption was 6.6 kWh,equivalent to 206.40 kWh/month.A 1.2-kWp and 1.2-m^(3)hybrid solar-biogas system was found to adequately power the ***,the total initial investment cost of the system was$5777.20 with a net present value of$6566.78,net profit of$4443.6,a payback period of 14 years and 8 months,and a levelized cost of energy of$0.21/kWh;these include a 60%initial investment and maintenance costs *** performance contracting and energy-as-a-service were recommended to effectively run and operate the *** study successfully revealed the design,specifications and upscaling mechanism of the proposed hybrid solar-biogas *** research is required to unveil the efficacy of the system,the performance gap and the perception of the technology by the beneficiaries.

关键词： energy access sustainable rural development clean energy waste management post-COVID-19 recovery plan

Analysis of the Impact of the Blazhko Effect Both on the Van Hoof Effect and Radial Velocity Amplitude in the Star RR lyr

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Research in Astronomy and Astrophysics 2024年第6期24卷 253-272页

作者： Y.El jariri F.l.Sefyani A.Benhida Z.Benkhaldoun k.k.l.nberg k.Chafouai A.Habib M.Sabil Observatoire de l'Oukaimeden LPHEAFSSMUniversitéCadi AyyadMarrakech2390Morocco Observatoire de l'Oukaimeden LPHEAFSTGUniversitéCadi AyyadMarrakech549Morocco Département de physique Universitéd'Anvers Avenue Groenenborger 171Anvers2020Belgium lICPM ENSA-BMUniversitéSultan Moulay SlimaneBeni-Mellal23020Morocco

The Van Hoof effect is a phase shift existing between the radial velocity curves of hydrogen and metallic lines within the atmosphere of pulsating *** this article,we present a study of this phenomenon through the spectra of the brightest pulsating star RR lyr of RR lyrae stars recorded for 22 *** based ourselves,on the one hand,on 1268 spectra(41 nights of observation)recorded between the years 1994 and 1997 at the Observatory of Haute Provence(OHP,France)previously observed by Chadid and Gillet,and on the other hand on 1569 spectra(46nights of observation)recorded at our Oukaimeden Observatory(Morocco)between 2015 and *** this study,we have detected information on atmospheric dynamics that had not previously been ***,the Van Hoof effect which results in a clear correlation between the radial velocities of hydrogen and those of the metallic lines has been observed and analyzed at different Blazhko phases.A correlation between the radial velocities of different metallic lines located in the lower atmosphere has been observed as *** the first time,we were able to show that the amplitude of the radial velocity curves deduced from the lines of hydrogen and that of FeⅡ(λ4923.921?)increases toward the minimum of the Blazhko cycle and decreases toward the maximum of the same Blazhko ***,we found that the Van Hoof effect is also modulated by the Blazhko ***,toward the minimum of the Blazhko cycle the Van Hoof effect is more visible and at the maximum of the Blazhko cycle,this effect is *** also observed the temporal evolution of the amplitudes of the radial velocities of the lower and upper *** observed over a long time,we can interpret it as a function of the Blazhko phases.

关键词： stars:atmospheres stars:variables:RR lyrae shock waves techniques:spectroscopic techniques:radial velocities stars:individual(RR lyr)