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Dynamic magnetic hysteresis in a liquid suspension of acicular maghemite particles

Particuology 2009年第6期7卷 451-458页

作者： bronislav e.kashevsky Sergey B.kashevsky Igor V.Prokhorov A.V.Luikov Heat and Mass Transfer Institute Belarus Academy of SciencesP.Brovka str.15Minsk 220072Belarus

This paper presents theoretical and experimental studies on the magnetodynamics and energy absorption in a dilute suspension of small ferromagnetic particles with magnetic hysteresis and mechanical mobility in an AC magnetic field. experiments with 0.1% suspensions of acicular particles of gamma ferric oxide in solid and liquid matrices, subjected to a 430 Hz magnetic field with an intensity of up to 1200 Oe, revealed important role of particle mobility. The main qualitative and quantitative features of the phenomenon are in agreement with a model of joint magneto-mechanical dynamics of particles with a chain-of-spheres mode of incoherent magnetic reversal.

关键词： High-coercive magnetic particles Magnetic suspensions Dynamic magnetic hysteresis

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Study of cobalt ferrite nanosuspensions for low-frequency ferromagnetic hyperthermia

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Particuology 2008年第5期6卷 322-333页

作者： bronislav e.kashevsky Vladimir e.Agabekov Sergei B.kashevsky Katsiaryna A.Kekalo elena Yu.Manina Igor V.Prokhorov Vladimir S.Ulashchik A.V.Luikov Heat and Mass Transfer Institute Belarus Academy of Sciences P.Brovka Str.15Minsk 220072Belarus Institute of Chemistry of New Materials Belarus Academy of SciencesSkoriny Str.36Minsk 220141Belarus Institute of Physiology Belarus Academy of SciencesAkademicheskaiy Str.28Minsk 220072Belarus

High-coercive cobalt ferrite nanoparticles were synthesized and studied for magnetic hyperthermia by direct injection of their suspension into a tumor and application of a strong audio-frequency magnetic field for heating. Physical （dynamic magnetic hysteresis and heat generation in both liquid and solid dispersions）, biological （toxicity and penetration of particles in therapeutic quantities into mouse tumor tissue） as well as other properties of the particles were studied. A model was developed to describe the magnetodynamics in suspensions of magnetic nanoclusters with an account for both Brownian and regular rotations, to provide understanding of observed phenomena. The experimental and theoretical techniques developed have formed a basis for controllable synthesis of the magnetic nanoparticles for low-frequency heat generation in medical and other applications.

关键词： Cobalt ferrite nanoparticles Magnetic suspensions Dynamic magnetic hysteresis Medical hyperthermia

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