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Using on-site.live. 3-D re.onstruction and volume.ric calculations in split live. transplantation

He.atobiliary & Pancre.tic Dise.se. Inte.national 2016年第6期15卷 587-592页

作者： Tre.or w Re.chman brittany Fiore.lo Ian Carmody Humbe.to Bohorque. Ari Cohe. John Se.l David Bruce.Ge.rge.e.Loss Ochsne. Multi-Organ Transplant Institute Ochsner Medical Center

BACKGROUND： Split live. transplantation incre.se. the.numbe. of grafts available.for transplantation. Pre.re.ove.y asse.sme.t of live. graft volume.is e.se.tial for se.e.ting suitable.re.ipie.ts. The.purpose.of this study was to de.e.mine.the.ability and fe.sibility of constructing a 3-D mode. to aid in surgical planning and to pre.ict graft we.ght prior to an in situ division of the.donor live.. Me.HODS： Ove. 11 months, 3-D volume.ric re.onstruction of 4 de.e.se. donors was pe.forme. using Pathfinde. Scout live. volume.ric software. De.ographic, laboratory, ope.ative. pe.iope.ative.and survival data for the.e.patie.ts along with donor de.ographic data we.e.colle.te. prospe.tive.y and analyze. re.rospe.tive.y. Re.ULTS： The.ave.age.pre.icte. we.ght of the.grafts from the.adult donors obtaine. from an in situ split proce.ure.we.e.1130 g （930-1458 g） for the.e.te.de. right lobe.donors and 312 g （222-396 g） for le.t late.al se.me.t grafts. Actual adult graft we.ght was 92% of the.pre.icte. we.ght for both the.e.te.de. right grafts and the.le.t late.al se.me.t grafts. The.pre.icte. and actual graft we.ghts for the.pe.iatric donors we.e.176 g and 210 g for the.le.t late.al se.me.t grafts and 308 g and 280 g for the.e.te.de. right lobe.grafts,re.pe.tive.y. All grafts we.e.transplante. e.ce.t for the.right lobe.from the.pe.iatric donors due.to the.small graft ***： On-site.volume.ric asse.sme.t of donors provide. use.ul information for the.planning of an in situ split and for se.e.tion of re.ipie.ts. This information may e.pand the.donor pool to re.ipie.ts pre.iously fe.t to be.unsuitable.due.to donor and/or re.ipie.t we.ght.

关键词： split live. transplantation re.uce.-size.live. transplantation 3-D re.onstruction

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Curre.t state.of laparoscopic parastomal he.nia re.air:A me.a-analysis

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world Journal of Gastroe.te.ology 2015年第28期21卷 8670-8677页

作者： Francis J De.sis brittany Lapin Matthe. e.Gite.is Michae. B Ujiki Se.tion of Minimally Invasive.Surge.y Department of Surgery North Shore University Health System

AIM:To e.aluate.the.e.ficacy and safe.y of the.laparoscopic approache. for parastomal he.nia re.air re.orte. in the.***:A syste.atic re.ie. of PubMe. and Me.LINe.database. was conducte. using various combination of the.following ke.words:stoma re.air,laparoscopic,parastomal,and *** re.orts,studie. with le.s than 5 patie.ts,and article. not writte. in e.glish we.e.*** studie. we.e.furthe. scrutinize. with the.2011 le.e.s of e.ide.ce.from the.Oxford Ce.tre.for e.ide.ce.Base. *** authors re.ie.e. and analyze. e.ch *** the.e.was any discre.ancy be.we.n score.,the.study in que.tion was re.e.re. to anothe. author.A me.a-analysis was pe.forme. using both random and fixe.-e.fe.t *** bias was e.aluate. using Be.g's funne. plot and e.ge.'s re.re.sion *** primary outcome.analyze. was re.urre.ce.of parastomal *** outcome. we.e.me.h infe.tion,surgical site.infe.tion,obstruction re.uiring re.pe.ation,de.th,and othe. *** we.e.groupe. by ope.ative.te.hnique.whe.e.*** for re.urre.ce.most postope.ative.morbiditie. we.e.re.orte. for the.ove.all cohort and not by approach so the. we.e.analyze. across ***:Fifte.n article. with a total of 469 patie.ts we.e.de.me. e.igible.for *** postope.ative.morbiditie. we.e.re.orte. for the.ove.all cohort,and not by *** ove.all postope.ative.morbidity rate.was 1.8%(95%CI:0.8-3.2),and the.e.was no diffe.e.ce.be.we.n *** most common postope.ative.complication was surgical site.infe.tion,which was se.n in 3.8%(95%CI:2.3-5.7).Infe.te. me.h was obse.ve. in 1.7%(95%CI:0.7-3.1),and obstruction re.uiring re.pe.ation also occurre. in 1.7%(95%CI:0.7-3.0).Othe. complications such as ile.s,pne.monia,or urinary tract infe.tion we.e.note. in16.6%(95%CI:11.9-22.1).e.ghty-one.re.urre.ce. we.e.re.orte. ove.all for a re.urre.ce.rate.of 17.4%(95%CI:9.5-26.9).The.re.urre.ce.rate.was 10.2%(95%CI:3.9-19.0) for the.modif

关键词： Parastomal He.nia Laparoscopic Re.air Tre.tme.t Sugarbake. Ke.hole Sandwich Ile.stomy Colostomy

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e.fe.ts of diurnal te.pe.ature.range.on adult size.and e.e.ge.ce.time. from diapausing pupae.in Papilio glaucus and R canade.sis （Papilionidae.

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Inse.t Scie.ce 2011年第4期18卷 435-442页

作者： J. Mark Scribe. brittany Sonke De.artme.t of e.tomology Michigan State University East Lansing Michigan McGuire.Ce.te. for Le.idopte.a and Biodive.sity Flonda Museum of Natural History University of Florida Gainesville Florida USA

with re.e.t climate.warming tre.ds, both the.incre.se.in the.mal variance.（i.e., diurnal te.pe.ature.range. DTR） as we.l as incre.se. me.n te.pe.ature.may impact many diffe.e.t organisms, e.pe.ially poikilothe.mic inve.te.rate.. Pre.ictions of inse.t de.e.opme.tal rate. using de.re.-days （the.mal unit accumulations above.the.de.e.opme.tal base.thre.hold of the.inse.t） are.base. on daily me.n te.pe.ature., re.ardle.s of DTR. Howe.e., non-line.rity and variance.in the.me.ns and e.tre.e. are.ofte. ignore.. The.role.of the.mal variance.（e.g., daily te.pe.ature.e.tre.e. and DTR） was e.aluate. e.pe.ime.tally for two swallowtail butte.fly siste. spe.ie. using a common day/night photope.iod of 18 ： 6 h photo ： scoto-phase.and corre.ponding daytime.the.mophase.and nighttime.cryophase.pe.iods of 22 ： 22℃ （constant 22℃）, 24 ： 16℃, and 26 ： 10℃（all thre. tre.tme.ts had the.same.daily me.n and the.same.de.re.-day accumulations）. Although de.e.opme.tal rate. ofpost-diapause.pupae.we.e.large.y unaffe.te. for both spe.ie., our re.ults show that size. in P canade.sis fe.ale. （but not male.） we.e.smalle. in the.tre.tme.ts with more.variance.（26℃ ： 10℃） compare. to constant 22℃. Such pote.tially significant impacts of size.re.uction in P canade.sis fe.ale. we.e.not obse.ve. in P glaucus male. or fe.ale. unde. the.same.se.ie. ofthe.mo-pe.iod tre.tme.ts.

关键词： climate.warming de.re.-days diurnal te.pe.ature.range.(DTR) photope.iods swallowtail butte.flie. the.mope.iods

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e.fe.ts of Hops (<i>Humulus lupulus</i>L.) Be.a-Acids on Short Chain Fatty Acid Production from Comple. Carbohydrate. by Rume. Microbiota

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Advance. in Microbiology 2019年第12期9卷 983-992页

作者： Michae. D. Flythe.brittany e. harl.w Forage.Animal Production Re.e.rch Unit Agricultural Research Service USDA Lexington KY USA De.artme.t of Animal and Food Scie.ce. College of Agriculture Food and the Environment University of Kentucky Lexington KY USA

The.aim of this e.pe.ime.t was to de.e.mine.the.e.fe.ts of be.a-acids, pre.ylate. phe.olic compounds from the.hops plant, on fe.me.tation of individual carbohydrate. by rume. microorganisms. Mixe., uncultivate. rume. microbiota was harve.te. from rume. fistulate. ste.rs and washe. to make.ce.l suspe.sions. The.suspe.sions we.e.use. to inoculate.me.ia with a glucan, fructan or constitue.t sugar, and fe.me.tation was e.aluate. by production of short-chain fatty acids (SCFA). Hops be.a-acid (30 ppm) was not unive.sally inhibitory, but e.ch of the.SCFA (ace.ate. propionate.or butyrate. was de.re.se. (P e.or more.of e.ch ce.lulose.or starch te.te.. The.fe.me.tation of sugars and fructans (short- or long-chain inulins) was not impacte. by the.phytoche.icals. Pre.ious re.ults have.shown that hops and hops e.tracts had the.be.e.icial e.fe.ts of re.ucing rume. ammonia and me.hane. The.curre.t re.ults indicate.that both starch and ce.lulose.fe.me.tation could be.impacte.. Be.ause.ce.lulose.fe.me.tation is nutritionally important on forage.base. die.s, hops phytoche.icals might have.more.utility in ce.e.l grain-base. rations.

关键词： Rume. Microbiota Fibe. Phytoche.ical Fe.d Antibiotic

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Crite.ia for le.e. 1 and le.e. 2 trauma code.: Are.pe.vic ring injurie. unde.triage.?

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world Journal of Orthope.ics 2016年第8期7卷 481-486页

作者： brittany e.Haws Scott wue.tze. Laura Raffie.d Le.n Le.chik Anna N Mille. wake.Fore.t School of Me.icine Medical Center Boulevard De.artme.t of Radiology Medical Center Boulevard De.artme.t of Mole.ular Ge.e.ics and Ge.omics Medical Center Boulevard De.artme.t of Orthopae.ic Surge.y Medical Center Boulevard

AIM: To de.e.mine.the.association of unstable.pe.vic ring injurie. with trauma code.***: A re.rospe.tive.re.ie. of all pe.vic ring injurie. at a single.acade.ic ce.te. from July 2010 to June.2013 was pe.forme.. The.trauma re.istry was use. to ide.tify le.e. 1 and le.e. 2 trauma code. for e.ch injury. The.compute. tomography scans in all patie.ts we.e.classifie. as stable.or unstable.using the.Abbre.iate. Injury Scale. Pe.vic injury classifications in le.e. 1 and le.e. 2 groups we.e.compare.. Patie.t disposition at discharge.in le.e. 1 and le.e. 2 groups we.e.also ***: The.e.we.e.108 le.e. 1 and 130 le.e. 2 blunt trauma admissions. In the.le.e. 1 group, 67% of pe.vic injurie. we.e.classifie. as stable.fracture.patte.ns and 33% we.e.classifie. as unstable. In the.le.e. 2 group, 62% of pe.vic injurie. we.e.classifie. as stable.fracture.patte.ns and 38% we.e.classifie. as unstable. le.e. 1 trauma code.was not associate. with odds of having an unstable.fracture.patte.n(OR = 0.83, 95%CI: 0.48-1.41, P = 0.485). In the.le.e. 1 group with unstable.pe.vic injurie., 33% we.e.discharge. to home. 36% to a re.abilitation facility, and 32% die.. In the.le.e. 2 group with unstable.pe.vic injurie., 65% we.e.discharge. to home. 31% to a re.abilitation facility, and 4% die.. For those.with unstable.pe.vic fracture.(n = 85), assignme.t of a le.e. 2 trauma code.was associate. with re.uce. odds of de.th(OR = 0.07, 95%CI: 0.01-0.35, P = 0.001) as compare. to be.ng discharge. to ***: Trauma code.le.e. assignme.t is not corre.ate. with se.e.ity of pe.vic injury. Be.ause.an unstable.pe.vis can le.d to he.odynamic instability, the.e.injurie. may be.unde.triage..

关键词： Pe.vic ring Trauma code Triage Unstable pe.vis Abbre.iate. injury scale

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e.fe.ts of Spe.t Craft Bre.e.s’ Ye.st on Fe.me.tation and Me.hane.Production by Rume. Microorganisms

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Advance. in Microbiology 2016年第9期6卷 716-723页

作者： Virginia L. Pszczolkowski Robe.t w. Bryant brittany e. harl.w Gle. e. Aike. Langdon J. Martin Michae. D. Flythe De.artme.t of Che.istry Warren Wilson College Asheville NC USA Ashe.ille.Flavor Innovations LLC Asheville NC USA Forage.Animal Production Re.e.rch Unit Agricultural Research Service USDA Lexington KY USA De.artme.t of Animal and Food Scie.ce. University of Kentucky Lexington KY USA

Saccharomyce. ce.e.isiae.is a ke. compone.t of be.r bre.ing and a major by-product. The.le.tove., spe.t bre.e.s’ ye.st from large.bre.e.ie. has be.n use. as a prote.n supple.e.t in cattle.howe.e. the.possible.advantage. of spe.t ye.st from smalle. craft bre.e.ie., containing much highe. le.e.s of bioactive.hop acids, have.not be.n e.aluate.. Hops se.ondary me.abolite. from the.hops (Humulus lupulus L.) use. to make.be.r are.conce.trate. in the.ye.st during bre.ing, and have.antimicrobial activity against Gram-positive.bacte.ia. Uncultivate. suspe.sions of bovine.rume. microorganisms produce. le.s me.hane.during fructose.fe.me.tation whe. e.pose. to inactivate., and fre.ze.drie. spe.t craft bre.e.s’ ye.st than a bake.s’ ye.st control. The.e.pe.ime.t was re.e.te. with caprine.rume. microorganisms and ground grass hay as the.substrate. Like.ise. in the.pre.e.ce.of craft bre.e.s’ ye.st le.s me.hane.was produce. (2.7% vs. 6.9% CH4). Both e.pe.ime.ts also re.e.le. a de.re.se.in ace.ic acid production, but not propionic acid production, whe. craft bre.e.s’ ye.st was include.. The.e.re.ults indicate. that spe.t ye.st could re.re.e.t a co-product for craft bre.e.ie., and a fe.d supple.e.t for ruminants that has a favorable.impact on me.hane.production.

关键词： Antimicrobials Bre.ing Co-Product Fe.d Supple.e.t Fe.d e.ficie.cy Hops Acids Humulus Lupulus Plant Se.ondary Me.abolite Phytoche.icals

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A Fle.ible.Boundary Proce.ure.for Hype.bolic Proble.s: Multiple.Pe.alty Te.ms Applie. in a Domain

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Communications in Computational Physics 2014年第7期16卷 541-570页

作者： Jan Nordstrom Qaisar Abbas brittany A.e.ickson Hanne. Fre.ande. De.artme.t of Mathe.atics Division of Computational MathematicsLinkoping UniversitySE-58183 Link¨opingSweden De.artme.t of Information Te.hnology Division of Scientific ComputingUppsala UniversitySE-75105 UppsalaSweden De.artme.t of Ge.logical Scie.ce. San Diego State UniversitySan DiegoCA 92182-1020USA De.artme.t of Mathe.atics Division of Computational MathematicsLinkoping UniversitySE-58183 Link¨opingSweden.

A ne. we.k boundary proce.ure.for hype.bolic proble.s is *** conside. high orde. finite.diffe.e.ce.ope.ators of summation-by-parts form with we.k boundary conditions and ge.e.alize.that *** ne. boundary proce.ure.is applie. ne.r boundarie. in an e.te.de. domain whe.e.data is *** show how to raise.the.orde. of accuracy of the.sche.e.how to modify the.spe.trum of the.re.ulting ope.ator and how to construct non-re.le.ting prope.tie. at the.*** ne. boundary proce.ure.is che.p,e.sy to imple.e.t and suitable.for all nume.ical me.hods,not only finite.diffe.e.ce.me.hods,that e.ploy we.k boundary *** re.ults that corroborate.the.analysis are.pre.e.te..

关键词： Summation-by-parts we.k boundary conditions pe.alty te.hnique high-orde. accuracy finite.diffe.e.ce.sche.e. stability ste.dy-state non-re.le.ting boundary conditions

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From signalling pathways to targe.e. the.apie.: unrave.ling glioblastoma’s se.re.s and harne.sing two de.ade. of progre.s

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Signal Transduction and Targe.e. The.apy 2023年第11期8卷 5270-5302页

作者： brittany De.dne. Misty RJe.kins Sarah ABe.t Saskia Fre.tag Krishne.l Prasad Je.f Holst Rae.e.e.e.de.sby Te.rance.GJohns Cance. Ce.tre Telethon Kids InstituteNedlandsWA6009Australia Ce.tre.For Child He.lth Re.e.rch University of Western AustraliaPerthWA6009Australia Immunology Division The Walter and Eliza Hall Institute of Medical ResearchMelbourne3052Australia De.artme.t of Me.ical Biology University of MelbourneMelbourne3010Australia Pe.sonalise. Oncology Division The Walter and Eliza Hall Institute of Medical ResearchMelbourne3052Australia School of Biome.ical Scie.ce. University of New South WalesSydney2052Australia

Glioblastoma,a rare.and highly le.hal form of brain cance.,pose. significant challe.ge. in te.ms of the.ape.tic re.istance.and poor survival rate. for both adult and pae.iatric patie.ts *** advance.e.ts in brain cance. re.e.rch drive. by a te.hnological re.olution,translating our unde.standing of glioblastoma pathoge.e.is into improve. clinical outcome. re.ains a critical unme. *** re.ie. e.phasise. the.intricate.role.of re.e.tor tyrosine.kinase.signalling pathways,e.ige.e.ic me.hanisms,and me.abolic functions in glioblastoma tumourige.e.is and the.ape.tic *** also discuss the.e.te.sive.e.forts ove. the.past two de.ade. that have.e.plore. targe.e. the.apie. against the.e.*** the.ape.tic approache.,such as antibody-toxin conjugate. or CAR T ce.l the.apie.,offe. pote.tial by spe.ifically targe.ing prote.ns on the.glioblastoma ce.l *** strate.ie. incorporating prote.n-targe.e. the.apy and immune.base. the.apie. de.onstrate.gre.t promise.for future.clinical ***,gaining insights into the.role.of ce.l-of-origin in glioblastoma tre.tme.t re.ponse.holds the.pote.tial to advance.pre.ision me.icine.*** the.e.challe.ge. is crucial to improving outcome. for glioblastoma patie.ts and moving towards more.e.fe.tive.pre.ision the.apie..

关键词： glioblastoma the.apie. targe.e.

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The.he.lth be.e.its of se.e.ium in food animals:a re.ie.

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Journal of Animal Scie.ce.and Biote.hnology 2022年第6期13卷 1623-1633页

作者： brittany M.Pe.oraro Die.o F.Le.l Alba Frias-De.Die.o Matthe. Browning Jack Odle.e.isa Crisci Colle.e.of Ve.e.inary Me.icine Department of Population Health and PathobiologyNorth Carolina State UniversityRaleighNorth CarolinaUSA Laboratory of De.e.opme.tal Nutrition Department of Animal ScienceNorth Carolina State UniversityRaleighNorth CarolinaUSA

Se.e.ium is an e.se.tial trace.mine.al important for the.mainte.ance.of home.stasis in animals and *** e.ince. a strong antioxidant,anti-inflammatory and pote.tial antimicrobial *** biological function is primarily achie.e. by its pre.e.ce.in se.e.oprote.ns as a form of *** de.icie.cy may re.ult in an array of he.lth disorde.s,affe.ting many organs and syste.s;to pre.e.t this,die.ary supple.e.tation,mainly in the.forms of organic(i.e.,se.e.ome.hionine.and se.e.ocyste.ne.inorganic(i.e.,se.e.ate.and se.e.ite.source. is *** pigs as we.l as othe. food animals,die.ary se.e.ium supple.e.tation has be.n use. for improving growth pe.formance.immune.function,and me.t quality.A substantial body of knowle.ge.de.onstrate. that die.ary se.e.ium supple.e.tation is positive.y associate. with ove.all animal he.lth e.pe.ially due.to its immunomodulatory activity and prote.tion from oxidative.*** also posse.se. pote.tial antiviral activity and this is achie.e. by prote.ting immune.ce.ls against oxidative.damage.and de.re.sing viral *** this re.ie. we.e.de.vor to combine.e.tablishe. and nove. knowle.ge.on the.be.e.icial e.fe.ts of die.ary se.e.ium supple.e.tation,its antioxidant and immunomodulatory actions,and the.putative.antimicrobial e.fe.t ***,our re.ie. de.onstrate. the.gaps in knowle.ge.pe.taining to the.use.of se.e.ium as an antiviral,unde.scoring the.ne.d for furthe. in vivo and in vitro studie.,particularly in pigs.

关键词： Antimicrobial Antioxidant Food animals Immunomodulation Pig Se.e.ium

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Control of Glyphosate.Re.istant wate.he.p with Two-Pass we.d Control Strate.ie. in Glyphosate.Dicamba-Re.istant Soybe.n

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Ame.ican Journal of Plant Scie.ce. 2018年第7期9卷 1424-1432页

作者： brittany K. He.ge. Nade. Soltani David C. Hooke. Darre. e. Robinson Pe.e. H. Sikke.a Unive.sity of Gue.ph Ridgetown Campus Ridgetown Canada

wate.he.p is a small-se.de., dioe.ious, broadle.f we.d that e.e.ge. throughout the.growing se.son. If le.t uncontrolle., wate.he.p inte.fe.e.ce.can re.uce.soybe.n yie.d up to 73%. Glyphosate.re.istant (GR) wate.he.p was first discove.e. in one.county in Ontario in 2014;as of 2017, it has be.n found in two othe. countie.. Glyphosate.dicamba-re.istant soybe.n can be.spraye. with glyphosate.and/or dicamba pre.lant (PP), pre.me.ge.ce.(PRe. and/or poste.e.ge.ce.(POST). The.obje.tive.of this study was to de.e.mine.the.control of GR wate.he.p in glyphosate.dicamba-re.istant soybe.n with PRe.re.idual he.bicide., glyphosate.dicamba applie. POST or a two-pass program of a PRe.re.idual he.bicide.followe. by glyphosate.dicamba applie. POST. At 8 we.ks afte. application (wAA), pyroxasulfone.(150 g ai ha-1), S-me.olachlor/me.ribuzin (1943 g ai ha-1), pyroxasulfone.sulfe.trazone.(300 g ai ha-1) and flumioxazin/pyroxasulfone.(240 g ai ha-1), applie. PRe. re.ulte. in 71%, 85%, 82% and 90% GR wate.he.p control, re.pe.tive.y. The.same.PRe.he.bicide., followe. by glyphosate.dicamba (1800 g ae.ha-1) POST, improve. control to gre.te. than 96%. This study conclude. that a two-pass program of an e.fe.tive.soil applie. re.idual he.bicide.followe. by glyphosate.dicamba POST controlle. GR wate.he.p in glyphosate.dicamba-re.istant soybe.n.

关键词： wate.he.p Soybe.n Glyphosate Re.istance Glyphosate Dicamba

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