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Origins of the problematic E in SEIR epidemic models

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Infectious Disease Modelling 2024年第3期9卷 673-679页

作者： Donald S.burke Distinguished University Professor Emeritus of Health Science and Policy Department of EpidemiologySchool of Public HealthUniversity of PittsburghUSA

During the COVID-19 pandemic,over one thousand papers were published on“Susceptible-Exposed-Infectious-Removed”(SEIR)epidemic computational *** English word“exposed”in its vernacular and public health usage means a state of having been in contact with an infectious individual,but not necessarily *** contrast,the term“exposed”in SEIR modeling usage typically stands for a state of already being infected but not yet being infectious to others,a state more properly termed“latently infected.”In public health language,“exposed”means possibly infected,yet in SEIR modeling language,“exposed”means already *** paper retraces the conceptual and mathematical origins of this terminological disconnect and concludes that epidemic modelers should consider using the“SLIR”notational short-hand(L for Latent)instead of SEIR.

关键词： SEIR model Exposed Latent infection History Notation

Comparison of methods for deriving phenotypes from incomplete observation data with an application to age at puberty in dairy cattle

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Journal of Animal Science and Biotechnology 2024年第2期15卷 535-545页

作者： Melissa A.Stephen Chris R.burke Jennie E.Pryce Nicole M.Steele Peter R.Amer Susanne Meier Claire V.C.Phyn Dorian J.Garrick DairyNZ Ltd 605 Ruakura RoadHamilton 3240New Zealand AL Rae Centre for Genetics and Breeding-Massey University RuakuraHamilton 3214New Zealand Agriculture Victoria Research AgriBioCentre for AgriBioscienceBundooraVictoria 3083Australia School of Applied Systems Biology La Trobe UniversityBundooraVictoria 3083Australia AbacusBio DunedinNew Zealand

Background Many phenotypes in animal breeding are derived from incomplete measures,especially if they are challenging or expensive to measure *** include time-dependent traits such as reproductive status,or *** measures for these traits result in phenotypes that are subject to left-,interval-and rightcensoring,where phenotypes are only known to fall below an upper bound,between a lower and upper bound,or above a lower bound *** we compare three methods for deriving phenotypes from incomplete data using age at first elevation(>1 ng/mL)in blood plasma progesterone(AGEP4),which generally coincides with onset of puberty,as an example *** We produced AGEP4 phenotypes from three blood samples collected at about 30-day intervals from approximately 5,000 Holstein–Friesian or Holstein–Friesian×Jersey cross-bred dairy heifers managed in 54 seasonal-calving,pasture-based herds in New *** used these actual data to simulate 7 different visit scenarios,increasing the extent of censoring by disregarding data from one or two of the three *** methods for deriving phenotypes from these data were explored:1)ordinal categorical variables which were analysed using categorical threshold analysis;2)continuous variables,with a penalty of 31 d assigned to right-censored phenotypes;and 3)continuous variables,sampled from within a lower and upper bound using a data augmentation *** Credibility intervals for heritability estimations overlapped across all methods and visit scenarios,but estimated heritabilities tended to be higher when left censoring was *** sires with at least 5 daughters,the correlations between estimated breeding values(EBVs)from our three-visit scenario and each reduced data scenario varied by method,ranging from 0.65 to *** estimated breed effects also varied by method,but breed differences were smaller as phenotype censoring *** Our results indicate that using

关键词： Cattle Gibbs sampler Markov-chain Monte Carlo(MCMC) Puberty

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全球担保品管理行业发展趋势分析

债券 2024年第1期 68-69页

作者：布傲迪(O’Delle burke) 摩根大通

面对全球经济的不稳定性、复杂性,担保品作为理想的风险和流动性管理工具,吸引了越来越多市场投资者的关注,监管机构的重视程度不断提高,担保品管理机制的重要性逐步提升。市场随之对担保品管理的流转效率、精细化程度提出了更高层次的... 详细信息

面对全球经济的不稳定性、复杂性,担保品作为理想的风险和流动性管理工具,吸引了越来越多市场投资者的关注,监管机构的重视程度不断提高,担保品管理机制的重要性逐步提升。市场随之对担保品管理的流转效率、精细化程度提出了更高层次的要求,不断促进担保品选取分配算法的优化升级,金融科技在担保品领域的应用不断拓展,担保资产配置效率提升。尽管如此,新形势下全球市场仍然面临着优质担保品短缺的难题,人民币债券作为稳健、优质的资产,能够成为国际担保品池的有效补充。

关键词：担保品行业发展趋势人民币债券流动性管理流转效率资产配置效率监管机构管理机制

Review on supercapacitors:Technologies and performance evaluation

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Journal of Energy Chemistry 2021年第8期30卷 276-291,I0006页

作者： Jingyuan Zhao Andrew F.burke Institute of Transportation Studies University of California-Davis95616 DavisUSA Computer Science and Technology Shenzhen Institutes of Advanced TechnologyChinese Academy of Sciences518118 ShenzhenChina

The development of electrochemical capacitors(***)have attracted a lot of attention in recent years because of the increasing demand for efficient,high-power energy *** capacitors(ECs)are particularly attractive for transportation and renewable energy generation applications,taking advantage of their superior power capability and outstanding cycle *** the past decade,various advanced electrode materials and cell design are being studied to improve the energy density of *** Li-ion capacitors and pseudo-capacitors that utilize fast surface redox reactions of metal oxide and doped polymers are the prime candidates being *** paper is concerned with the metrics being used to describe the performance of ECs and how the metrics are evaluated by testing devices and how the data from the testing are best *** is on relating testing of advanced ECs using materials more complex than activated carbons to testing electric double-layer capacitors(EDLCs)using carbon in both electrodes.A second focus of the paper is projecting the potential of the advanced materials and ionic liquid electrolytes for the development of complete EC cells having an energy density more than a factor of ten greater the energy density of the EDLC devices currently on the *** potential was evaluated by calculating the performance(energy and power)of a series of ECs that utilize the advanced materials that have been studied by electrochemists over the past 10-15 *** capacitance and resistance of the advanced ECs were calculated utilizing specific capacitance(F/g or F/cm^(3))and porosity data for the electrode materials and ionic conductivity of the *** was concluded that hybrid ECs can be developed with energy densities of at least 50 Wh/kg,70 Wh/L with efficient power greater than 3 k W/*** research on micro-porous carbons with specific capacitance of 200 F/g and greater is *** achieve th

关键词： Electrochemical capacitors Metrics Evaluation Cell design Applications

From the lab to the world： The paradigmatic assumption and the functional cognition of avian foraging

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Current Zoology 2015年第2期61卷 328-340页

作者： Danielle SULIKOWSKI Darren burke School of Psychology Charles Sturt University Bathurst NSW 2795 Australia School of Psychology University of Newcastle Ourimbah NSW 225 Australia

Mechanisms of animal learning and memory were traditionally studied without reference to niche-specific functional considerations. More recently, ecological demands have informed such investigations, most notably with respect to foraging in birds. In parallel, behavioural ecologists, primarily concerned with functional optimization, have begun to consider the role of mechanistic factors, including cognition, to explain apparent deviations from optimal predictions. In the present paper we discuss the application of laboratory-based constructs and paradigms of cognition to the real-world challenges faced by avian foragers. We argue that such applications have been handicapped by what we term the ＇paradigmatic assumption＇ - the assumption that a given laboratory paradigm maps well enough onto a congruent cognitive mechanism （or cognitive ability） to justify confiation of the two. We present evidence against the paradigmatic assumption and suggest that to achieve a profitable integration between function and mechanism, with respect to animal cognition, a new conceptualization of cognitive mechanisms - functional cogni- tion - is required. This new conceptualization should define cognitive mechanisms based on the informational properties of the animal＇s environment and the adaptive challenges faced. Cognitive mechanisms must be examined in settings that mimic the im- portant aspects of the natural environment, using customized tasks designed to probe defined aspects of the mechanisms＇ opera- tion. We suggest that this approach will facilitate investigations of the functional and evolutionary relevance of cognitive mecha- nisms, as well as the patterns of divergence, convergence and specialization of cognitive mechanisms within and between species .

关键词： Functional cognition Paradigmatic assumption Informational properties Avian foraging

Battery prognostics and health management for electric vehicles under industry 4.0

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能源化学:英文版 2023年第9期84卷 30-33页

作者： Jingyuan Zhao Andrew F.burke Institute of Transportation Studies University of California DavisDavisCA 95616USA

Transportation electrification is essential for decarbonizing transport. Currently, lithium-ion batteries are the primary power source for electric vehicles (EVs). However, there is still a significant journey ahead before EVs can establish themselves as the dominant force in the global automotive market. Concerns such as range anxiety, battery aging, and safety issues remain significant challenges.

关键词： Lithium-ion battery Prognostics and health management Machine learning Cloud Artificial intelligence Digital twins Lifelong learning

Cognitive Stylistics： History, Development and Current Applications

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外国语 2010年第1期33卷 40-46页

作者： Michael burke Roosevelt Academy Middelburg U. S. A

Drawing on contrasting authoritative definitions,this article starts by investigating the question 'what is cognitive stylistics' and the related sub questions 'how has cognitive stylistics developed over the past two decades' and 'how does it differ from what is known as cognitive poetics'.Having established a consensus on what it is,the article then moves on to a much more important issue:the practical matter of how scholars might optimally employ cognition in their stylistic ***,the article introduces the original notions of 'mono-conceptual approaches' and 'integrative approaches' based on previous cognitive stylistic analyses conducted by the author.A pedagogical argument is then made in preference of the *** one is left with is an emerging categorical state of affairs in cognitive stylistic research and practice that fellow scholars are encouraged to reflect on and revise,if deemed necessary,in order to further knowledge in the field of cognitive stylistics.

关键词：英语文体论语言学教学方法

Overview of Sudden Cardiac Deaths

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Journal of Forensic Science and Medicine 2022年第4期8卷 157-169页

作者： Allen burke Department of Pathology School of MedicineUniversity of MarylandBaltimoreMDUSA

Sudden cardiac death(SCD)is an unexpected cardiac death that is instantaneous or occurs within a short period of time after onset of symptoms,in a person in a stable state of *** has either a certain etiology(for example,cardiac tamponade or fresh occlusive coronary thrombus),or has one or more morphologic substrates that increase the risk of electrical instability that in turn can lead to a fatal *** latter group of SCD has been assigned as either highly probable or uncertain etiologies,according to guidelines of the Association of European Cardiovascular *** review describes definitive causes and potential underlying substrates for SCD.

关键词： Sudden cardiac death pathology cardiomegaly

Polyelectrolyte multilayer electrostatic gating of graphene field-effect transistors

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Nano Research 2014年第11期7卷 1650-1658页

作者： Yung Yu Wang Peter J. burke Department of Chemical Engineering and Materials Science University of California Irvine Irvine California 92697 USA Department of Electrical Engineering and Computer Science University of California Irvine Irvine California 92697 USA

We apply polyelectrolyte multilayer films by consecutive alternate adsorption of positively charged polyallylamine hydrochloride and negatively charged sodium polystyrene sulfonate to the surface of graphene field effect transistors. Oscillations in the Dirac voltage shift with alternating positive and negative layers clearly demonstrate the electrostatic gating effect in this simple model system. A simple electrostatic model accounts well for the sign and magnitude of the Dirac voltage shift. Using this system, we are able to create p-type or n-type graphene at will. This model serves as the basis for understanding the mechanism of charged polymer sensing using graphene devices, a potentially technologically important application of graphene in areas such as DNA sequencing, biomarker assays for cancer detection, and other protein sensing applications.

关键词： dirac point graphene transistor electrostatic gating polyallylaminehydrochloride (PAH) sodium polystyrenesulfonate (PSS)