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电针对坐骨神经分支选择性损伤大鼠脊髓与背根神经节抑制性氨基酸水平的影响

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中华中医药杂志 2011年第9期26卷 2090-2093页

作者：刘跃光闫丽萍 brian jackson 马骋徐恒泽南京中医药大学教务处南京210029 南京中医药大学江苏省针灸学重点实验室南京210029 美国巴尔的摩中西医结合治疗中心巴尔的摩21234

目的:探讨电针对神经病理性痛大鼠痛觉过敏及其相应脊髓节段与背根神经节(DRG)抑制性氨基酸水平的影响。方法:健康雄性SD大鼠,逐一进行基础痛阈测定,剔除痛阈过高和过低者后,随机分出空白组、假手术组(均为n=10)和模型动物组。模型动物... 详细信息

目的:探讨电针对神经病理性痛大鼠痛觉过敏及其相应脊髓节段与背根神经节(DRG)抑制性氨基酸水平的影响。方法:健康雄性SD大鼠,逐一进行基础痛阈测定,剔除痛阈过高和过低者后,随机分出空白组、假手术组(均为n=10)和模型动物组。模型动物组待模型成功后将其随机分为模型组和电针组(均为n=10)。采用坐骨神经分支选择性损伤(SNI)模型,电针"委中"和"环跳"穴,观察其对大鼠机械痛阈和热痛阈的影响,以OPA柱前衍生法+HPLC荧光检测法测定脊髓及其相应节段DRG内γ-氨基丁酸(GABA)、甘氨酸(Gly)和牛磺酸(Tau)水平的变化。结果:SNI手术可明显降低大鼠机械痛阈,在脊髓相应节段,其GABA和Tau含量均增加(P<0.05,P<0.01),Gly含量则降低(P<0.05);电针干预后脊髓GABA含量进一步增加(P<0.05),Gly含量被逆转(P<0.05),Tau无明显变化;而在DRG、SNI手术使GABA和Gly水平均增加(P<0.01),Tau降低(P<0.05);电针干预后Gly和Tau均被明显逆转(P<0.05),GABA虽也有逆转的趋势,但无统计学差异;同时电针组SNI大鼠的机械痛敏状态及痛行为均明显减轻和改善。结论:电针通过有效地增加脊髓GABA和Gly的释放,同时抑制DRG内GABA和Gly的释放,可能是其干预神经病理性痛的脊髓机制之一。

关键词：电针神经病理性痛脊髓背根神经节抑制性氨基酸递质

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并置的世界舞台

艺术界 2010年第3期 86-93页

作者：布莱恩·基思·杰克逊可海恩德·维里

今年北京的冬天来得早去得迟。三月末,艺术家可海恩德·维里站在北京繁忙的首都机场,而他的沉甸甸的护照此刻正躺在登机柜台上。这是他在尤伦斯当代艺术中心举办的“可海恩德·维里：联合体传奇”展览开幕几星期之后。而此前,为配合“... 详细信息

今年北京的冬天来得早去得迟。三月末,艺术家可海恩德·维里站在北京繁忙的首都机场,而他的沉甸甸的护照此刻正躺在登机柜台上。这是他在尤伦斯当代艺术中心举办的“可海恩德·维里：联合体传奇”展览开幕几星期之后。而此前,为配合“联合体”展览——该展览展出了运动品牌PUMA委任其创w作的．以三位来自非洲大陆不同地区的足坛明星，

关键词：舞台世界并置首都机场艺术中心非洲大陆运动品牌联合体

An unusual cause of acute anemia in an immunosuppressed patient

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Gastroenterology Report 2016年第3期4卷 254-256,I0003页

作者： Jamak Modaresi Esfeh Whitney jackson Kianoush Ansari-Gilani brian Putka Department of Gastroenterology&Hepatology Cleveland ClinicClevelandOHUSA Department of Diagnostic Radiology Washington UniversitySt.LouisMOUSA

Gastrointestinal mucormycosis is an uncommon,invasive,opportunistic fungal infection with a high mortality rate,seen more commonly in immunocompromised *** lethal infection has a wide range of presentations,from colonization of peptic ulcers to infiltrative disease and eventually vascular *** we present a case of upper gastrointestinal bleeding in an immunocompromised patient,which was proved to be secondary to gastric involvement by mucormycosis.

关键词： gastrointestinal bleeding gastric mucormycosis

Genic C-Methylation in Soybean Is Associated with Gene Paralogs Relocated to Transposable Element-Rich Pericentromeres

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Molecular Plant 2018年第3期11卷 485-495页

作者： Moaine El Baidouri Kyung Do Kim brian Abernathy Ying-Hui Li Li-Juan Qiu Scott A. jackson Center for Applied Genetic Technologies University of Georgia 111 Riverbend Road Athens GA 30602 USA Corporate R&D LG Chem LG Science Park 30 Magokjungang 10-ro Gangseo-gu Seoul 07796 Republic of Korea The National Key Facility for Crop Gene Resources and Genetic Improvement (NFCRI) Institute of Crop Science Chinese Academy of Agricultural SciencesBeijing China These authors contributed equally to this article.

Most plants are polyploid due to whole-genome duplications （WGD） and can thus have duplicated genes. Following a WGD, paralogs are often fractionated （lost） and few duplicate pairs remain. Little attention has been paid to the role of DNA methylation in the functional divergence of paralogous genes. Using high- resolution methylation maps of accessions of domesticated and wild soybean, we show that in soybean, a recent paleopolyploid with many paralogs, DNA methylation likely contributed to the elimination of ge- netic redundancy of polyploidy-derived gene paralogs. Transcriptionally silenced paralogs exhibit partic- ular genomic features as they are often associated with proximal transposable elements （TEs） and are pref- erentially located in pericentromeres, likely due to gene movement during evolution. Additionally, we provide evidence that gene methylation associated with proximal TEs is implicated in the divergence of expression profiles between orthologous genes of wild and domesticated soybean, and within populations.

关键词： soybean paralog gene methylation proximal transposable element methylation spreading

Development of a Test Apparatus for Measurement of Hydraulic Fluid Efficiency

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润滑油 2011年第5期26卷 28-33页

作者： Matt jackson brian Koehler Southwest Research Institute

With increasing demand for nonrenewable resources,energy conservation is *** gains allow more work to be performed while maintaining or even decreasing the energy expended in the *** the energy consumed by a system results in favorable economic and environmental *** apparatus has been developed to measure hydraulic fluid efficiency in a stationary *** system can be used to develop more efficient fluids,leading to increased work output or decreased energy consumption.

关键词： mechanical and volumetric efficiency test pump test procedure

Removal of Copper from Acid Mine Drainage (AMD) or Acid Rock Drainage (ARD)

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Journal of Water Resource and Protection 2021年第7期13卷 435-454页

作者： Agabu Shane Xinyang Xu John Siame Alick Nguvulu Tewodros Mitiku Tena Musango Lungu Sydney Chinyanta jackson Kawala Victor Mwango Bowa brian Chirambo Department of Mining Engineering School of Mines and Mineral Sciences Copperbelt University Kitwe Zambia Department of Environmental Engineering College of Natural Resources and Civil Engineering Northeastern University Shenyang China Department of Chemical Engineering School of Mines and Mineral Sciences Copperbelt University Kitwe Zambia Department of Geomatics Engineering School of Mines and Mineral Sciences Copperbelt University Kitwe Zambia Department of Environmental Engineering School of Mines and Mineral Sciences Copperbelt University Kitwe Zambia

Acid mine drainage is wastewater from a mine having a low pH and an elevated level of dissolved heavy metals. These metals are harmful to aquatic, animal and human life. This paper looks at the removal of copper from acid mine drainage using ion exchange to less than 1 mg/l. A weak acidic cation resin was used. Spectrophotometric determination of copper with sodium diethyldithiocarbamate was used to determine the copper concentrations in the treated water. Using regression analysis, the experimental results gave a correlation coefficient of 0.977 and a coefficient of determination of 99.5%. Results indicated that the higher the flows rate the shorter the period after which the copper concentration in the treated water reaches 1 mg/l. At pH 3.85 and 5.09, the resin performed better and at pH above 6.62 and between pH 3.0 and below the resin’s does not perform well. The higher the resin height the greater is the resin exchange capacity and the longer it takes for the copper concentration to reach 1 mg/l in the treated water. The higher the wastewater copper concentration the shorter the time it takes the resin to reach 1 mg/l. The results for this experiment indicated that acid mine drainage can be treated well by ion exchange resins, but it is also very important to establish suitable operating conditions.

关键词： Acid Mine Drainage Copper Ion Exchange Resin and Spectrophotometry

Remote sensing and analysis of tropical cyclones:Current and emerging satellite sensors

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Tropical Cyclone Research and Review 2023年第4期12卷 267-293页

作者： Lucrezia Ricciardulli brian Howell Christopher R.jackson Jeff Hawkins Joe Courtney Ad Stoffelen Sebastian Langlade Chris Fogarty Alexis Mouche William Blackwell Thomas Meissner Julian Heming Brett Candy Tony McNally Masahiro Kazumori Chinmay Khadke Maria Ana Glaiza Escullar Remote Sensing Systems Santa RosaCAUSA Joint Typhoon Warning Center Pearl HarborHawaiiUSA Global Ocean Associates(supporting NOAA/NESDIS STAR) AlexandriaVAUSA University of Wisconsin Cooperative Institute for Meteorological Satellite StudiesMadisonWIUSA Bureau of Meteorology PerthAustralia Royal Netherlands Meteorological Institute(KNMI) De BiltNetherlands Tropical Cyclone/Regional Specialized Meteorological Center Meteo FranceReunionFrance Canadian Hurricane Center(CHC) DartmouthNova ScotiaCanada University Brest CNRSIRDIfremerLaboratoire d’Oceanographie Physique et Spatiale(LOPS)IUEMBrestFrance MIT Lincoln Laboratory LexingtonMAUSA Met Office ExeterUK European Centre for Medium-Range Weather Forecasts ReadingUK Japan Meteorological Agency(JMA) TokyoJapan India Meteorological Department(IMD) New DelhiIndia Philippine Atmospheric Geophysical and Astronomical Services Administration(PAGASA)Diliman Quezon CityPhilippines

This article describes recent advances in the capability of new satellite sensors for observing Tropical Cyclones(TC)fine structure,wind field,and temporal *** article is based on a World Meteorological Organization(WMO)report prepared for the 10th International Workshop on Tropical Cyclones(IWTC),held in Bali in December 2022,and its objective is to present updates in TC research and operation every four *** we focus on updates regarding the most recent space-based TC observations,and we cover new methodologies and techniques using polar orbiting sensors,such as C-band synthetic aperture radars(SARs),L-band and combined C/X-band radiometers,scatterometers,and microwave imagers/*** additionally address progress made with the new generation of geostationary and small satellites,and discuss future sensors planned to be launched in the next *** then briefly describe some examples on how the newest sensors are used in operations and data assimilation for TC forecasting and research,and conclude the article with a discussion on the remaining challenges of TC space-based observations and possible ways to address them in the near future.

关键词： Tropical cyclones Surface wind Satellite sensors Operations

The Triple Gene Block 1 Movement Protein of the ND18 Strain of Barley Stripe Mosaic Virus is an Avirulence Determinant That Elicits Brachypodium distachyon Bd3-1 resistance

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The Triple Gene Block 1 Movement Protein of the ND18 Strain ...

Genome-wide SNP Genotyping Resolves Signatures of Selection and Tetrasomic Recombination in Peanut

中国植物病理学会2012年学术年会

作者： LEE Mi-Yeon Florien Gorter brian Y.T Kim Jessica Grindheim Uma Ganesan Andrew O.jackson Department of Plant & Microbial Biology University of California-BerkeleyBerkeleyCA 94720USA

Barley stripe mosaic virus(BSMV) North Dakota 18(ND18),Norwich(NW),Beijing (BJ),Xinjiang(XJ),Type and CV21 strains elicit different phenotypic responses on Brachypodium distachyon, a cereal grass model for ***18 is unable to infect the Brachypodium Bd3-1 inbred line,which contains a recently mapped resistance gene designated Bsr1(Cui et *** ONE,2012, 7(6);e38333).Along with ND18,the BJ,XJ,Type and CV21 strains also failed to produce visible symptoms or virus on Bd3-1,so it is possible that Bsr1 mediates resistance against all five BSMV strains. In contrast,NW overcomes Bd3-1 resistance and is accompanied by an intense mosaic phenotype and large amounts of *** of ND18 and NW genomic RNAs,and a series of chimeric exchanges within RNAβdemonstrate that Bd3-1 phenotypes are mediated by a region within the helicase motif of *** of this region reveals that the ND18 and NW strains contain divergent amino acids at positions 390,392 and 404 within this region,and that the inability of ND18 and the BJ,XJ,Type and CV21 strains to elicit fully virulent BSMV infections on Bd3-1 correlates with a threonine(T) at position 392(T).The virulent NW strain contains K residues at both the 390 and 392 positions and a glutamate (E) residue at position *** substitutions to swap the ND18 and NW 404 residues failed to affect the respective disease ***,R390K and T392K single exchanges and a R390K/ T392K double mutant in ND18 RNA TGB1 resulted in virulent *** contrast,incorporation of single K390R or K392T mutations into the NW TGB1 protein background did not affect the susceptible disease phenotype,suggesting that the NW K and K residues compensate for each *** contrast, a K390R/K392T double mutant in the NW TGB1 background failed to develop fully systemic infections on Bd3-1,or accumulate detectable viral RNA,but prominent necrotic streaks radiating from the secondary leaf veins were *** experiments in toto

关键词： Barley stripe mosaic virus Brachypodium distachyon resistance ND18 strain avirulence determinants Triple Gene Block 1(TGB1)

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Molecular Plant 2017年第2期10卷 309-322页

作者： Josh Clevenger Ye Chu Carolina Chavarro Gaurav Agarwal David J. Bertioli Soraya C.M. LeaI-Bertioli Manish K. Pandey Justin Vaughn brian Abernathy Noelle A. Barkley Ran Hovav Mark Burow Spurthi N. Nayak Annapurna Chitikineni Thomas G. Isleib C. Corley Holbrook Scott A. jackson Rajeev K. Varshney Peggy Ozias-Akins Department of Horticulture and Institute of Plant Breeding Genetics & Genomics The University of Georgia 2356 Rainwater Road Tifton GA 31793 USA Center for Applied Genetic Technologies and Institute of Plant Breeding Genetics & Genomics The University of Georgia Athens GA 30602 USA International Crops Research Institute for the Semi-Arid Tropics (ICRISAT) Hyderabad 502324 India University of Brasilia Institute of Biological Sciences Campus Darcy Ribeiro 70910-900 Brasilia DF Brazil Embrapa Genetic Resources and Biotechnology 70770-917 Brasflia DF Brazil eUSDA-ARS PGRCU Griffin GA 30223 USA Agricultural Research Organization Plant Sciences Institute 7528809 Rishon LeZion Israel Department of Plant and Soil Science Texas Tech University Lubbock TX 79409-2122 USA Department of Crop and Soil Sciences North Carolina State University Box 7629 Raleigh NC 28695-7629 USA USDA-ARS Tifton GA 31793. USA

Peanut （Arachis hypogaea; 2n = 4x = 40） is a nutritious food and a good source of vitamins, minerals, and healthy fats. Expansion of genetic and genomic resources for genetic enhancement of cultivated peanut has gained momentum from the sequenced genomes of the diploid ancestors of cultivated peanut. To facil- itate high-throughput genotyping of Arachis species, 20 genotypes were re-sequenced and genome-wide single nucleotide poiymorphisms （SNPs） were selected to develop a large-scale SNP genotyping array. For flexibility in genotyping applications, SNPs polymorphic between tetraploid and diploid species were included for use in cultivated and interspecific populations. A set of 384 accessions was used to test the array resulting in 54 564 markers that produced high-quality polymorphic clusters between diploid species, 47 116 polymorphic markers between cultivated and interspecific hybrids, and 15 897 polymorphic markers within A. hypogaea germplasm. An additional 1193 markers were identified that illuminated genomic re- gions exhibiting tetrasomic recombination. Furthermore, a set of elite cultivars that make up the pedigree of US runner germplasm were genotyped and used to identify genomic regions that have undergone pos- itive selection. These observations provide key insights on the inclusion of new genetic diversity in culti- vated peanut and will inform the development of high-resolution mapping populations. Due to its efficiency, scope, and flexibility, the newly developed SNP array will be very useful for further genetic and breeding applications in Arachis.

关键词： single nucleotide polymorphism groundnut Arachis hypogaea