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Dynamic stress concentration in an infinitely long cylindrical cavity due to a point spherical source embedded within a fluid-saturated poroelastic formation of infinite extent

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 139-156页

作者： h.hOSSEINI O.BALILAShAKI Department of Mechanical Engineering Faculty of EngineeringGolestan University

The effects of a harmonically exciting monopole source on an infinitely long cylindrical cavity embedded entirely within a fluid-saturated poroelastic formation of infinite extent are examined theoretically. It is assumed that the source is located outside the cavity at a specified distance from the borehole axis. The magnitudes of the hoop and radial stresses beside the pore pressures exerted on the interface and inside the porous medium surrounding the borehole are calculated and discussed. Biot's poroelastic modeling along with three types of boundary conditions for the cylindrical interface including the ideal fluid, empty borehole, and rigid inclusion with a hard boundary is employed for the analysis. Utilizing a proper translational addition theorem for expressing the incident spherical wave in terms of cylindrical wave expansions, the proposed boundary conditions at the interface are satisfied. Stresses are formulated by means of wave potential functions in a three-dimensional(3D) manner. The effects of the frequency and the radial distance between the source and borehole on the induced stresses are examined for the first cylindrical modes over frequency spectra. Two permeability conditions for the interface and three types of soils for the porous formation are considered throughout the analysis. To give an overall outline of the study, a numerical example is presented. The results clearly indicate that the distance is a key parameter and has considerable effects on the induced stress values. In addition, the interface permeability condition and soil characteristics play an important role in determining the dynamic response of the borehole. Finally,the obtained results are compared with the relevant analyses existing in the literature for some limit cases, and good agreement is achieved.

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Neuroinflammation as a therapeutic target in huntington's disease

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Neural Regeneration Research 2025年第3期20卷 817-818页

作者： Andrea Kwakowsky Thulani h.Palpagama Center for Brain Research and Department of Anatomy and Medical Imaging Faculty of Medical and Health SciencesUniversity of AucklandAucklandNew Zealand Pharmacology and Therapeutics School of MedicineGalway Neuroscience CentreUniversity of GalwayGalwayIreland

In 1872, George huntington presented his essay “On Chorea” to the Meigs and Mason Academy of Medicine and, in doing so, detailed a disease that would later bear his name. huntington's disease(hD) is a genetic, neurodegenerative disease that manifests as the loss of motor control,cognitive impairment,and mood and psychiatric changes in paents.

关键词： huntington inflammation Medicine

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Glial response in the midcingulate cortex in huntington’s disease

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Neural Regeneration Research 2025年第1期20卷 207-208页

作者： Thulani h.Palpagama Andrea Kwakowsky Center for Brain Research and Department of Anatomy and Medical Imaging Faculty of Medical and Health SciencesUniversity of AucklandAucklandNew Zealand Pharmacology and Therapeutics School of MedicineGalway Neuroscience CenterUniversity of GalwayGalwayIreland

huntington’s disease(hD)is a genetic disease characterized by the progressive degeneration of the striatum and *** can present with a variety of symptoms that can broadly be classified into motor symptoms,inclusive of choreatic movements and rigidity,mood and psychiatric symptoms,such as depression and apathy,and cognitive symptoms,such as cognitive *** causal mutation underlying hD results from an expansion of a CAG repeat sequence on the IT15 gene,resulting in the formation and accumulation of a mutant huntingtin protein.

关键词： huntington degeneration cortex

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MULTIVARIATE OPTIMIZATION OF GENERALIZED BIN PACKING PROBLEM

MULTIVARIATE OPTIMIZATION OF GENERALIZED BIN PACKING PROBLEM

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第11届国际模糊系统协会世界大会

作者： Jong-Kyou KIM Kwang h.lee Core Technology Group TmaxSoft Dept.of BioSystems KAIST

＜正＞ Rectangles represent units of planning in many engineering problems such as multiprocess scheduling or stock cutting problems. The size of each rectangle, however, is not precisely determined at the time of planning. The fuzzy bin packing problem enables modeling this uncertainty by representing the height of the rectangle as a fuzzy number, which represent the satisfaction of the piece. As the satisfaction degree becomes smaller, the height value of a fuzzy piece becomes smaller. The previous research solved the minimization problem by simplifying the satisfaction degree to be a single variable, i.e., all the satisfaction degrees are the same. With this simplification, the previous research showed that we could further minimize the total cost by optimizing the variable. To extend the research, this paper proposes a multivariate optimization algorithm for the fuzzy bin packing problem. The algorithm is composed of two phases. In the first phase, it finds an initial packing using conventional bottom-left heuristics. Then, it optimizes the satisfaction degree using enhanced gradient descent optimizer. The enhanced gradient descent algorithm avoids local optima problem caused by structural changes caused by applying different satisfaction degrees.

关键词： Fuzzy bin packing Multivariate optimization Scheduling Stock cutting

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臭氧对墨西哥豆瓢虫取食和生长的影响

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昆虫学报 1990年第2期33卷 161-165页

作者：吴亚 Edward h.lee Edward M.Barrows 江苏省农业科学院植物保护研究所美国农业部农业研究中心植物抗逆实验室美国乔治城大学生物系

本文报道在美国农业研究中心用臭氧在室内熏蒸和田间开顶熏蒸植物,用此饲养墨西哥豆瓢虫的实验,以及熏蒸后植物体内某些化合物含量变化的测定。结果表明,墨西哥豆瓢虫(Epilachna varivestis Mulsant)喜食臭氧(O_3)污染的植物,幼虫取食O_... 详细信息

本文报道在美国农业研究中心用臭氧在室内熏蒸和田间开顶熏蒸植物,用此饲养墨西哥豆瓢虫的实验,以及熏蒸后植物体内某些化合物含量变化的测定。结果表明,墨西哥豆瓢虫(Epilachna varivestis Mulsant)喜食臭氧(O_3)污染的植物,幼虫取食O_3污染植物后蛹显著重于取食未受污染植物所形成的蛹。根据豆瓢虫食性和植物体内糖含量的测定,可以认为,低浓度O_3污染导致植物体内糖含量的增加,是促使豆瓢虫取食量和蛹重增加的重要因素。

关键词：墨西哥豆瓢虫臭氧取食生长

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3个不同苹果品种果实品质及对1-MCP的吸附释放规律

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果树学报 2015年第2期32卷 291-297页

作者：董晓庆朱守亮 James h.lee Donald J.huber 贵州省果树工程技术研究中心.贵州大学农学院贵阳550025 贵州省果树蔬菜工作站贵阳550025 美国佛罗里达州佛罗里达大学盖恩斯维尔110690

【目的】探讨生产上苹果不同品种贮藏保鲜理论依据和技术。【方法】以3个苹果品种‘旭’、‘嘎拉’、‘蜜脆’为试验材料,用1-甲基环丙烯(1-MCP)进行处理,分析研究了其采收时的品质及对1-MCP的吸附释放特性规律。【结果】‘旭’、‘嘎... 详细信息

【目的】探讨生产上苹果不同品种贮藏保鲜理论依据和技术。【方法】以3个苹果品种‘旭’、‘嘎拉’、‘蜜脆’为试验材料,用1-甲基环丙烯(1-MCP)进行处理,分析研究了其采收时的品质及对1-MCP的吸附释放特性规律。【结果】‘旭’、‘嘎拉’、‘蜜脆’3个苹果品种硬度、可溶性固形物含量、可滴定酸、固酸比和果肉颜色之间的差异显著(Ph后,内部积累的1-MCP量显著不同,其中‘蜜脆’积累的最多,其次为‘嘎拉’,‘旭’果实内部基本没有积累;而瓶内的1-MCP消耗量没有差别(12 h后,‘旭’、‘嘎拉’和‘蜜脆’瓶内1-MCP消耗量分别为18.3%,17.3%和18.9%)。经过100μL·L-11-MCP于20℃下处理6 h后取出,1-MCP从不同品种果实向外释放的速率和释放量显著不同(Ph,‘嘎拉’的释放速率和释放量最大,3 h后,‘蜜脆’的释放速率和释放量最大,‘旭’的释放速率和释放量一直最小。【结论】‘旭’、‘嘎拉’、‘蜜脆’3个不同苹果品种在采后时的品质、内部乙烯含量以及对1-MCP的反应特性不同。经1-MCP处理后,内部积累的1-MCP量显著不同:‘旭’、‘嘎拉’和‘蜜脆’对1-MCP的吸附量(6 h)分别为16.2%、19.8%和7.0%。

关键词：苹果品种 1-甲基环丙烯吸附扩散品质

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Temperature and Thermal Stress Distribution for Metal Mold in Squeeze Casting Process

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Journal of Materials Science & Technology 2008年第3期24卷 347-350页

作者： C.h.lee S.h.lee Institute of Technology and Science Chung-Ang University

In the squeeze casting process, loaded high pressure （over approximately 200 MPa） and high temperature influence the thermo-mechanical behavior and performance of the used metal mold. Therefore, to safely maintain the metal molds, the thermo-mechanical characteristics （temperature and thermal stress） of metal mold in the squeeze casting must be investigated. In this paper, temperature and thermal stress distribution of steel mold in squeeze casting process were investigated by using a three-dimensional non-steady heat conduction analysis and a three-dimensional thermal elastic-plastic analysis considering temperature-dependent thermophysical and mechanical properties of the steel mold.

关键词： Squeeze casting Steel mold Thermal stress Thermo-Mechanical analysis

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Development of Fully Functional Miniature Unmanned Rotorcraft Systems

Development of Fully Functional Miniature Unmanned Rotorcraf...

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第二十九届中国控制会议

作者： Ben M.ChEN Tong h.lee Department of Electrical and Computer Engineering National University of Singapore

We document in this article a general introduction to modern miniature unmanned rotorcraft *** specifically,we present a fairly detailed overview on the hardware configuration,software integration,aerodynamic modeling... 详细信息

关键词： Unmanned Aerial Vehicles Aerodynamic Modeling Avionic Systems Flight Control Systems Computer VisionSystems

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Phase stability and mechanical properties of wire+arc additively manufactured h13 tool steel at elevated temperatures

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Journal of Materials Science & Technology 2021年第8期67卷 80-94页

作者： A.N.M.Tanvir Md.R.U.A hsan Gijeong Seo brian Bates Chanho lee Peter K.Liaw Mark Noakese Andrzej Nycz Changwook Ji Duck Bong Kim Department of Mechanical Engineering Tennessee Technological UniversityCookevilleTN 38505USA Department of Manufacturing and Engineering Technology Tennessee Technological UniversityCookevilleTN 38505USA Center for Manufacturing Research Tennessee Technological UniversityCookevilleTN 38505USA Department of Materials Science and Engineering University of TennesseeKnoxvilleTN 37996USA Manufacturing Demonstration Facility Oak Ridge National LaboratoryOak RidgeTN 37830USA Advanced Forming Process R&D Group Korea Institute of Industrial TechnologyUlsan 44413Republic of Korea

Wire+arc additive manufacturing(WAAM)is considered an innovative technology that can change the manufacturing landscape in the near *** offers the benefits of inexpensive initial system setup and a high deposition rate for fabricating medium-and large-sized parts such as die-casting *** this study,AISI h13 tool steel,a popular die-casting tool metal,is manufactured by cold metal transfer(CMT)-based WAAM and is then comprehensively analyzed for its microstructural and mechanical ***-dependent phase combinations are observed,which could be explained by nonequilibrium thermal cycles that resulted from the layer-by-layer stacking mechanism used in *** addition,remelting and reheating of the layers reduces welding anomalies(e.g.,pores and voids).The metallurgical characteristics of the h13 strongly correlate with the mechanical *** combinations of phases at different locations of the additively manufactured part exhibit a periodic microhardness ***,Retained Austenite,Ferrite,and Carbide phases are found in combination at different locations of the part based on the part’s temperature distribution during additive ***,the tensile properties at elevated temperatures(23℃,300℃,and 600℃)are comparable to those from other WAAM and additive manufacturing(AM)*** X-ray diffraction results verify that the microstructural stability of the fabricated parts at high temperatures would allow them to be used in high temperatures.

关键词： Tool steel Martensitic steel Wire+arc additive manufacturing(WAAM) high temperature tensile test high temperature XRD

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Does mesenchymal stem cell’s secretome affect spinal sensory circuits?Implication for pain therapies

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Neural Regeneration Research 2025年第1期20卷 181-183页

作者： Francesco Ferrini Esri h.Juárez Adalberto Merighi Department of Veterinary Sciences University of TurinGrugliascoTOItaly Department of Psychiatry and Neuroscience UniversitéLavalQuébec CityQCCanada

Mesenchymal stem cells(MSCs)are multipotent adult stem cells of mesodermal origin that can be isolated from various tissues,including bone marrow,tooth pulp,adipose tissue,and umbilical *** have gained significant attention in regenerative medicine due to their ability to modulate the immune system and favor tissue *** enrich the medium in which they are cultivated with a broad range of bioactive molecules,including growth factors,cytokines,chemokines,enzymes,nucleic acids,and extracellular vesicles that collectively compose the MSC *** increasing number of pre-clinical studies suggest that delivering in vivo an MSC-conditioned medium(i.e.,the medium collected from MSC cultures after at least 3 days of exposure)exerts neuroprotective and anti-inflammatory effects in a variety of neurological conditions.

关键词： protective clinical collective

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