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Mechanical Design of Long-Term Body-Adhered Medical Devices to Maximize On-Body Survival

Journal of Biomedical Science and Engineering 2021年第9期14卷 325-337页

作者： brian ferry John Abraham University of St. Thomas St. Paul MN USA

Long-term, body-adhered medical devices rely on an adhesive interface to maintain contact with the patient. The greatest threat to on-body adhesion is mechanical stress imparted on the medical device. Several factors contribute to the ability of the device to withstand such stresses, such as the mechanical design, shape, and size of the device. This analysis investigates the impact that design changes to the device have on the stress and strain experienced by the system when acted on by a stressor. The analysis also identifies the design changes that are most effective at reducing the stress and strain. An explicit dynamic finite element analysis method was used to simulate several design iterations and a regression analysis was performed to quantify the relationship between design and resultant stress and strain. The shape, height, size, and taper of the medical device were modified, and the results indicate that, to reduce stress and strain in the system, the device should resemble a square in shape, be short in height, and small in size with a large taper. The square shape experienced 17.5% less stress compared to the next best performing shape. A 10% reduction in device height resulted in a 21% reduction in stress and 24% reduction in strain. A 20% reduction in device size caused a 7% reduction in stress and 2% reduction in strain. A 20% increase in device taper size led to a negligible reduction in stress and a 6% reduction in strain. The height of the device had the greatest impact on the resultant stress and strain.

关键词： Finite Element Analysis Explicit Dynamics Numerical Simulation Comparative Analysis Medical Device Body-Worn Device Mechanical Design

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Case Study of Biodiesel-Diesel Blends as a Fuel in Marine Environment

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Advances in Chemical Engineering and Science 2011年第2期1卷 65-71页

作者： Tianxi Zhang Yapeng Chao Nan Liu Joe Thompson Manuel Garcia brian B. He Jon Van Gerpen Shulin Chen 不详

Formation of excessive sludge and fuel filter clogging were experienced in using biodiesel blends under marine environment. In this study, a field test was conducted in a marine ferry boat fueled by canola-based biodiesel blends. The sludge materials collected in the fuel purifier were characterized using inductively coupled plasma (ICP), pyrolysis-GC/MS (Py-GC/MS), thermogravimetric analysis (TGA), and Karl-Fischer titration. It was found that the sludge materials consisted of four distinctive fractions: organic materials derived from diesel and canola biodiesel (major fraction), ash (11-14% w/w), water (~17% w/w), and bacteria. The active bacteria were present in the sludge samples. It was suggested that bacterial contamination was one of the major factors in contribution to the sludge formation.

关键词： Biodiesel Sludge Filter Clogging Microorganisms Marine Environment

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