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NaiaTM醋酯纤维素纱线技术概要及加工要点

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纺织导报 2019年第9期 26-30页

作者：高建平李湧 brian edwards 美国伊士曼化工有限公司

醋酯纤维素纤维是一种源自天然材料的纤维品种,由于其独特的光学和机械性能,被称为最接近真丝的纤维之一。文章讨论了醋酯纤维素产品的各项性能,包括吸湿性及导电性能、拉伸等物理性能、耐化学品性能及降解性能、热塑性能等;并从纤维、... 详细信息

醋酯纤维素纤维是一种源自天然材料的纤维品种,由于其独特的光学和机械性能,被称为最接近真丝的纤维之一。文章讨论了醋酯纤维素产品的各项性能,包括吸湿性及导电性能、拉伸等物理性能、耐化学品性能及降解性能、热塑性能等;并从纤维、纱线、面料角度分析了亟需应用企业提升的加工要点,例如纱线保护、长丝加捻、针织织造、机织织造、染色及后整理等,为企业进行醋酯纤维素纱线产品的开发提供参考。

关键词：醋酯纤维素纤维性能加工要点

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欧盟特殊审评药品上市后安全监管措施研究

药物评价研究 2021年第6期44卷 1149-1156页

作者：吴宏辉宋海波张力杨天绎马玉芳杨玉涵黄举凯 edwards brian 杨晓晖北京中医药大学东直门医院北京100700 国家药品监督管理局药品评价中心北京100022 北京中医药大学东方医院北京100078 罗格斯大学美国新泽西州08901 新药申请科学监管有限公司英国萨里郡KT22

经欧洲药品管理局(European Medicines Agency,EMA)特殊审评通道上市的药品在加速上市的同时,也需要接受更严格的上市后监管。通过文献分析的方法,在系统梳理相关法规和文献的基础上,对EMA特殊审评药品上市后安全监管体系及其特殊要求... 详细信息

经欧洲药品管理局(European Medicines Agency,EMA)特殊审评通道上市的药品在加速上市的同时,也需要接受更严格的上市后监管。通过文献分析的方法,在系统梳理相关法规和文献的基础上,对EMA特殊审评药品上市后安全监管体系及其特殊要求进行了分析和介绍,并结合中国药品审评审批改革和特殊审评药品上市后监管现状,从管理理念、法规建设、上市许可持有人制度以及药品再评价体系的建设和完善方面提出了政策建议。

关键词：欧盟药品管理局特殊审评上市后评价安全监管药物警戒

欧盟药品上市后安全性研究监管体系分析与思考

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药物评价研究 2021年第6期44卷 1141-1148页

作者：马玉芳吴宏辉张力宋海波黄举凯杨天绎温雅璐 edwards brian 杨晓晖北京中医药大学东方医院北京100078 北京中医药大学东直门医院北京100700 国家药品监督管理局药品评价中心北京100022 罗格斯大学美国新泽西州08901 新药申请科学监管有限公司英国萨里郡KT22

效益风险评估贯穿于药品整个的生命周期。为保障药品全生命周期最佳效益风险比,识别并针对药品风险因素采取适宜的风险最小化措施,积极开展药品上市后安全性研究尤为重要。欧洲药品管理局(European Medicines Agency,EMA)为了量化药品... 详细信息

效益风险评估贯穿于药品整个的生命周期。为保障药品全生命周期最佳效益风险比,识别并针对药品风险因素采取适宜的风险最小化措施,积极开展药品上市后安全性研究尤为重要。欧洲药品管理局(European Medicines Agency,EMA)为了量化药品的安全隐患,基于评估药物的效益风险状况并支持监管决策而开展上市后安全性研究(postauthorisation safety study,PASS),为保障其顺利开展而形成一套成熟的体系及监管流程。通过分析EMA开展PASS的制度及流程,提出建立健全监管体系、制定PASS指南及实施细则以及建立共享平台是丰富完善我国上市后安全评价体系的有效方式。

关键词：上市后安全性研究欧洲药品监管局药物警戒效益风险评估

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绿色建筑 4

2005年

作者：布莱恩·爱德华兹（brian edwards）朱玲郑志宇主译

本书由各个国家的专业人士共同完成，所引发的争论是对遍布世界各个角落的可持续发展设计的不同阐释，列举了6个不同地区的建筑设计，显示了多文化性和多学科性。

ISBN: (数字)7538142592

ISBN: (纸本)7538142592

关键词：工业技术建筑科学建筑设计

来源：汇雅图书（南通市图书馆... 评论

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国际药物警戒学会简介与启示

中国药物评价 2017年第2期34卷 141-146页

作者：张力田文杨唐雪周凌芸杨晓晖孙露 brian edwards Jean Christophe De lumeau Ian C.K.WONG Sten Olsson 北京中医药大学东方医院北京100078 辉瑞投资有限公司北京100010 赛诺菲(中国)投资有限公司上海分公司上海200040 NDA Regulatory Science Ltd. UK Bayer South East Asia Pte Ltd. Singapore Research Department of Practice and Policy School of PharmacyUniversity College LondonUK 香港大学李嘉诚医学院药理及药剂学系中国香港 WHO Collaborating Centre for International Drug Monitoring Sweden

药品风险管理贯穿于药品整个生命周期,药品风险效益评估是药品上市前审评与上市后评价的核心内容,积极深入地开展药物警戒活动是提高药品监管水平保障公众用药安全有效的重要环节。国际药物警戒学会(International Society of Pharmacov... 详细信息

药品风险管理贯穿于药品整个生命周期,药品风险效益评估是药品上市前审评与上市后评价的核心内容,积极深入地开展药物警戒活动是提高药品监管水平保障公众用药安全有效的重要环节。国际药物警戒学会(International Society of Pharmacovigilance,ISoP)是权威、独立、非营利性的国际性学术组织,是国际范围内公开、中立分享经验和知识的专业学术平台,旨在提升全球药物警戒的科学性,促进药物警戒和风险管理技术的发展。本文介绍了其组建发展、任务和学术交流方式等内容,提出ISoP为中国药品评价及药物警戒专业人员开启了一扇了解国际药物警戒技术和风险管理策略发展前沿的窗口,值得中国药品评价、药物警戒和药品安全领域科研、学术及医疗机构、药品生产经营企业及政府监管人员的充分关注与积极参与。

关键词：国际药物警戒学会药品评价药品安全药物警戒风险管理国际交流

Precise dating of abrupt shifts in the Asian Monsoon during the last deglaciation based on stalagmite data from Yamen Cave, Guizhou Province, China

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Science China Earth Sciences 2010年第5期53卷 633-641页

作者： edwards R. Lawrence Department of Geology and Geophysics University of Minnesota

Based on 33 U/Th dates and 1020 oxygen isotopic data from stalagmite Y1 from Yamen Cave, Guizhou Province, China, a record of the Asian Summer Monsoon (ASM) was established. The record covers the last deglaciation and the early Holocene (from 16.2 to 7.3 ka BP) with an average oxygen isotope resolution of 9 years. The main millennial-scale deglacial events first identified in Greenland (Greenland Interstadial Events: GIS 1e through GIS 1a) and later in China are clearly present in the Y1 record. By analogy to earlier work, we refer to these as Chinese Interstadials (CIS): CIS A.1e to CIS A.1a. The onset of these events in Y1 δ18O records are nominally dated at: 14750±50, 14100±60, 13870±80, 13370±80, and 12990±80 a BP. The end of CIS A.1a or the beginning of the Younger Dryas (YD) event is nominally at 12850±50 a BP and the end of the YD dates to 11500±40 a BP. The δ18O values shift by close to 3‰ during the transition into the Bφlling-Allerφd (BA, the onset of CIS A.1e) and at the end of the YD. Comparisons of Y1 to previously published early Holocene records show no significant phase differences. Thus, the East Asia Monsoon and the Indian Monsoon do not appear to have been out of phase during this interval. The Y1 record confirms earlier work that suggested that solar insolation and North Atlantic climate both affect the Asian Monsoon.

关键词： stalagmite Asian Monsoon the last deglaciation Holocene U-series dating Yamen Cave

Complicated responses of stalagmite δ ^(13)C to climate change during the last glaciation from Hulu Cave, Nanjing,China

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Science China Earth Sciences 2005年第12期48卷 2174-2181页

作者： R. L. edwards Department of Geology and Geophysics University of Minnesota MN 55455 USA

We present a record on carbon stable isotopic composition (δ 13C), covering 75 through 10 thousands years ago (ka B.P.), from Hulu Cave, Nanjing. The overlapping δ 13C pro-files are very similar in pattern and range, indicating that they mainly record climatic signal. Dur-ing the last glacial-interglacial transition, the >6‰ change of δ 13C values implies different con-tributions of C3 vs. C4 type plants in soils. On millennial scale, however, the increased calcite δ 13C during the warm Dansgaard-Oeschger (DO) events suggests a decrease of dissolved bio-genic CO2 when water flux rate through soil is large. This correlation between heavier δ 13C and higher precipitation is consistent with our previous report on the samples’ stable oxygen isotope records (Wang et al., 2001). Comparison of coeval δ 13C and δ 18O of stalagmites indicates that kinetic fractionation of carbon isotope is closely related to growth rate of stalagmites. This study also shows that local vegetation changes may lag behind precipitation changes by ~700 years during the deglaciation.

关键词： Hulu Cave stalagmite δ 13C last glacial period.

Anthropogenic Sulfate and Nitrate Signals in Snow from Bogda Glacier, Eastern Tianshan

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Journal of Earth Science 2011年第4期22卷 490-502页

作者：张晓宇 Ross edwards State Key Laboratory of Cryospheric Sciences/Tianshan Glaciological Station Cold and Arid Regions Environmental and Engineering Research Institute Chinese Academy of Sciences Graduate University of Chinese Academy of Sciences Desert Research Institute Reno NV 89512-1095 USA Curtin University of Technology Bentley WA6102 Australia

A 1.2 m snow pit was recovered on July 29th, 2009 from the Bogda Glacier, eastern Tianshan （天山）. The sample site temperature of -9.6 12 indicates that the unique glaciochemical re- cord was well preserved and suitable for the reconstruction of air pollution levels in this previously un- explored region. Samples were analyzed for major ions （Na＋, K＋, Ca2＋, Mg2＋, NH4＋, Cl-, SO42-, NO3-, HCOO＇, and CHaCOO）. NO3 and SO42were characterized by significant high levels of pollution con- centration. Most air masses backward trajectories ending in December 2008 have passed the Urumqi City center, while some even traveled across the primary nuclear weapons testing venue of the former Soviet Union （STS）. The mean pH value of snow samples is coincident with the average value of Urumqi＇s aerosol, and the ratio of [NO3-]/[SO42-] in the snow pit generally agrees with the value of the Urumqi winter aerosols. In addition, the [HCOO]/[CH3COO] ratio of snow samples is only 0.7, lower than unity. These analyses indicate that SO42 and NO3in the Bogda Glacier are the result of anthropo- genic pollutions.

关键词： anthropogenic pollutions SO42- NO3.

A Roadmap for Whitefly Genomics Research:Lessons from Previous Insect Genome Projects

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Journal of Integrative Agriculture 2012年第2期11卷 269-280页

作者： Owain Rhys edwards Alexie Papanicolaou CSIRO Ecosystem Sciences WembleyWA 6913Australia CSIRO Ecosystem Sciences CanberraACT 2601Australia

Due to evolving molecular and informatics technologies,modern genome sequencing projects have more different characteristics than what most biologists have become accustomed to during the capillary-based sequencing *** this paper,we explore the characteristics that made past insect genome projects successful and place them in the context of next-generation *** taking into account the intricacies of whitefly biology and the community,we present a roadmap for whitefly-omics,which focuses on the formation of an international consortium,deployment of informatic platforms and realistic generation of reference sequence data.

关键词： whole genome sequencing next generation sequencing transcriptome genome consortium white paper