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跨部门数据共享源于机构变革还是动机转变?——基于浙江省m区的案例研究

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管理世界 2024年第5期40卷 87-105页

作者：黄甄铭魏娜梁正清华大学公共管理学院北京邮电大学经济管理学院

跨部门数据共享是数字政府建设过程中的核心环节。基于不同阶段新兴数字技术采纳程度和数据共享效果存在差异的思考,研究以技术结构化理论为基础,在中国情境下结合影响数据共享的数据治理方式、数据共享动机两大关键要素,提出了“技术采... 详细信息

跨部门数据共享是数字政府建设过程中的核心环节。基于不同阶段新兴数字技术采纳程度和数据共享效果存在差异的思考,研究以技术结构化理论为基础,在中国情境下结合影响数据共享的数据治理方式、数据共享动机两大关键要素,提出了“技术采纳-组织结构”循环互动分析框架,并利用浙江省m区自1987年至2023年的跨部门数据共享实践个案进行实证检验。研究详细描述了数据治理方式演化、数据共享动机转变、数据共享效果提升的过程,并将演进历程划分为4个具有显著特征的阶段来展开理论分析。研究发现,在政府跨部门数据共享实践中,服务于数据共享的新兴数字技术采纳行为和中国情境下的条块分割组织结构特征间存在“制约-调适”的双向循环互动作用。条块分割的组织结构特征在一定程度上会形成对新兴数字技术采纳行为的“制约”,而后者亦可使前者带来的壁垒影响得以“调适”,最终互动结果影响跨部门数据共享的效果。尤为重要的是,二者互动的主导方向及限度受数据治理方式、数据共享动机两大要素的影响,并呈现阶段性演进特征。本研究结果彰显了推出“组合拳”的重要性,研究提出,在利用新兴数字技术促进数据共享过程中,既需要推进数据集中治理的机构变革,也需要引入激发数据共享动机的机制。

关键词：新兴数字技术技术采纳组织结构数据共享动机数据治理方式

Association of acute glycemic parameters at admission with cardiovascular mortality in the oldest old with acute myocardial infarction

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Journal of Geriatric Cardiology 2024年第3期21卷 349-358页

作者： Hui-Hui LIU meng ZHANG Yuan-Lin GUO Cheng-Gang ZHU na-Qiong WU Ying GAO Rui-Xia XU Jie QIAN Ke-Fei DOU Jian-Jun LI Cardiometabolic Center State Key Laboratory of Cardiovascular DiseaseFuwai HospitalNational Center for Cardiovascular DiseasesNational Clinical Research Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

OBJECTIVES Stress-related glycemic indicators,including admission blood glucose(ABG),stress-hyperglycemia ratio(SHR),and glycemic gap(GG),have been associated with worse outcomes after acute myocardial infarction(AmI).However,data regarding their prognostic value in the oldest old with AmI are ***,this study aimed to investigate the association of stress-related glycemic indicators with short-and long-term cardiovascular mortality(CVm)in the oldest old(≥80 years)with *** In this prospective study,a total of 933 consecutive old patients with AmI admitted to FuWai hospital(Beijing,China)were *** admission,ABG,SHR,and GG were assessed and all participants were classified according to their ***-meier,restricted cubic splines(RCS),and multivariate Cox regression analyses were performed to evaluate the association between these glycemic indicators and CVm within 30 days and long-term *** During an average of 1954 patient-years of follow-up,a total of 250 cardiovascular deaths were ***-meier analyses showed the lowest CVm in quartile 1 of ABG and in quartile 2 of SHR and *** adjusting for potential covariates,patients in quartile 4 of ABG,SHR,and GG had a respective 1.67-fold(95%CI:1.03-2.69;P=0.036),1.80-fold(95%CI:1.16-2.79;P=0.009),and 1.78-fold(95%CI:1.14-2.79;P=0.011)higher risk of long-term CVm risk compared to those in the reference groups(quartile 1 of ABG and quartile 2 of SHR and GG).Furthermore,RCS suggested a J-shaped relationship of ABG and a Ushaped association of SHR and GG with long-term ***,we observed similar associations of these acute glycemic parameters with 30-day *** Our data first indicated that SHR and GG consistently had a U-shaped association with both 30-day and longterm CVm among the oldest old with AmI,suggesting that they may be useful for risk stratification in this special population.

关键词： admitted infarction shaped

Dna methylation of SmPD3-based diagnostic biomarkers of naSH and mild fibrosis

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Genes & Diseases 2024年第1期11卷 99-102页

作者： na Wu mofan Feng Siran Yue Xinyu Shi nan Tang Yalan Xiong Jianying Wang Lei Zhang Hualing Song Yi Shi Guang He Guang Ji Baocheng Liu Shanghai Innovation Center of Traditional Chinese medicine Health Service School of Public HealthShanghai University of Traditional Chinese MedicineShanghai 201203China Institute of Digestive Diseases Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai 200032China Bio-X Institutes Key Laboratory for the Genetics of Developmental and Neuropsychiatric DisordersShanghai Jiao Tong UniversityShanghai 200030China Institute for Advancing Translational medicine in Bone and Joint Diseases School of Chinese MedicineHong Kong Baptist UniversityHong Kong SAR 999077China

Non-alcoholic fatty liver disease(naFLD)is a liver condition that is widely prevalent across the world.A considerable number of people with naFLD have the potential to progress to a more severe form of the condition known as nonalcoholic steatohepatitis(naSH),accompanied by bridging *** advancement is more likely if the patient has metabolic risk factors such as obesity or type 2 diabetes that deteriorate over ***,even slight inflammation or fibrosis in naFLD can significantly increase the likelihood of progression compared to steatosis *** underscores the importance of revising the present methods of monitoring naFLD patients to ensure early detection and effective management of the disease.

关键词： naFLD inflammation naSH

Influence of cerium ions on structure-dependent magnetic properties of Ba-Sr m-type hexaferrite nanocrystals

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Journal of Rare Earths 2024年第2期42卷 364-372,I0005页

作者： Ram A.Pawar Sunil m.Patange P.m.Dighe Sher Singh meena Abdullah GAl-Sehemi mehboobali Pannipara Santosh S.Jadhav Department of Physics ArtsCommerce and Science CollegeAhmednagar413711MaharashtraIndia Department of Physics Shri Krishna MahavidyalayaGunjotiDistOsmanabad413606MaharashtraIndia Padmashri Vikhe Patil College of Arts Science and CommercePravaranagarA/P.Loni(Kd)Tal.RahataDistAhmednagar413713MaharashtraIndia Solid State Physics Division Bhabha Atomic Research CentreMumbai400085MaharashtraIndia Department of Chemistry King Khalid UniversityAbha61413Saudi Arabia Department of Physics D.S.M's ArtsCommerce and Science CollegeJintur431509MaharashtraIndia

The present study is a systematic effort to investigate the structure-sensitive magnetic parameters of Ce^(3+) substituted Ba-Sr hexaferrite nanocrystals chemically formulated as Ba_(0.5)Sr_(0.5)Ce_(x)Fe_(12-x)O_(19) where x=0.0-0.2 with Δx=*** hexaferrite powders were prepared using the sol-gel self-ignition route and structurally characterized by means of powder X-ray diffraction and Fourier transform infrared *** creation of the m-type hexaferrite phase within the synthesized samples was revealed from the Rietveld refinement of the X-ray *** occurrence of a secondary phase of CeO_(2) was revealed within the hexaferrites for the substitution,x> *** refined X-ray diffraction data were utilized to compute the lattice parameters,X-ray density,and lattice parameter *** crystal structure plotted from the refined XRD data reveals the occupancy of the ions at different lattice *** XPS data of the hexaferrite were analyzed to confirm the oxidation states of the constituent *** nanocrystalline nature of the hexaferrites was revealed from the crystallite sizes calculated using Scherer's *** analysis of FTIR spectra confirms that only a fraction of Ce^(3+)accommodated in the lattice and the remaining Ce content reside in the form of the CeO_(2) *** morphology of the hexaferrites was analyzed from the FESEm profiles of the ferrite *** magnetic behavior study was performed by analyzing the Curie temperature,hysteresis loops,and hyperfine interactions by means of susceptibility,V.S.m,and mossbauer spectroscopy,*** hexaferrites with increasing coercivity,decreasing saturation magnetization,and decreasing Curie temperature are reported in the *** substituted Ce^(3+)ions inhibit the grain growth and create lattice imperfections giving rise to hexaferrites with tuned magnetic parameters suitable for different applications.

关键词： Ba-Sr hexaferrite Ce^(3+)substitution XPS Saturation magnetization Coercivity m?ssbauer spectroscopy

Synthesis of highly stable Ni nanoparticles via electrostatic self-assembly for enhanced hydrogen storage of mgH2

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Rare metals 2024年第9期43卷 4356-4366页

作者： Qin-Ke Tang Jiang-Chuan Liu Rui Shi Yun-Feng Zhu Ji-Guang Zhang Ya-na Liu Jun Wang Yao Zhang Xiao-Hui Hu Zhi-Bin Liu Li-Quan Li College of materials Science and Engineering Jiangsu Collaborative Innovation Centre for Advanced Inorganic Function CompositesNanjing Tech University School of materials Science and Engineering Southeast University

magnesium-based hydrides have been widely recognized as an appropriate choice for solid-state hydrogen ***,its undesirable thermodynamics and sluggish hydrogenation/dehydrogenation kinetics are major bottlenecks for its ***,a highly stable and highly dispersed Ni-based catalyst （Ni/Al2O3/GN） was fabricated to promote the hydrogen storage performance of mgH2via the electrostatic effect of NiAl-LDH/GN precursor with a co-calcination reduction ***2-5wt % Ni/Al2O3/GN exhibits excellent hydrogen storage performance,releasing about 5.7 wt % hydrogen in 3500 s at 250℃,and can reach a saturation hydrogen absorption of about 6.15 wt% in 3000 s at 100℃.Furthermore,it also shows low dehydrogenation apparent activation energy of 89.1 and 118.2 kJ·***,the catalyst ensures the stability of both the physical phase and structure during ball milling and cycling *** role of each phase in Ni/Al2O3/GN on the hydrogen storage performance of mgH2was also discussed through experiments and theoretical calculation,and the synergistic catalytic mechanism of Ni/Al2O3/GN was clearly *** work provides a unique perspective for the preparation of highly stable and highly dispersible catalysts.

关键词： Catalytic mechanism Hydrogen storage performance magnesium hydride Ni/Al2O3/GN

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纵向通风作用下隧道内氢泄漏爆炸隐患分析

西南交通大学学报 2024年第1期59卷 81-86页

作者：谢永亮吕娜西南交通大学机械工程学院四川成都610031

为研究纵向通风能否有效控制隧道中泄漏氢气的扩散以及降低可燃氢云的超压危害,本文以一长100 m的方形隧道为研究对象,利用FLUENT软件对隧道内氢气泄漏扩散现象进行数值模拟,基于可燃氢云爆炸超压对人和建筑物的危害分级,分析纵向通风... 详细信息

为研究纵向通风能否有效控制隧道中泄漏氢气的扩散以及降低可燃氢云的超压危害,本文以一长100 m的方形隧道为研究对象,利用FLUENT软件对隧道内氢气泄漏扩散现象进行数值模拟,基于可燃氢云爆炸超压对人和建筑物的危害分级,分析纵向通风降低隧道内氢气泄漏爆炸危害性的作用效果.研究结果表明:计算工况下,隧道内发生氢气射流火灾时的纵向风速范围为6.5~8.0 m/s;纵向通风能够有效控制隧道内氢气的泄漏和扩散,但不能完全消除隧道氢泄漏爆炸的可能性和危害性.

关键词：氢能隧道火灾爆炸数值模拟纵向通风临界风速

甲基化转移酶WTAP调节转录激活因子4表达加剧缺氧/复氧诱导的心肌细胞损伤

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中华危重病急救医学 2024年第3期36卷 279-285页

作者：杨娜曹敏成都市第三人民医院麻醉科四川成都610000 成都市第三人民医院泌尿外科四川成都610000

目的观察甲基化转移酶Wilms肿瘤蛋白1相关蛋白(WTAP)在缺氧/复氧(H/R)诱导的心肌细胞损伤中的调节作用及其分子机制。方法①实验一:将H9C2心肌细胞分为空白对照组和H/R模型组。采用H/R诱导H9C2细胞建立心肌缺血/再灌注(I/R)损伤模型;空... 详细信息

目的观察甲基化转移酶Wilms肿瘤蛋白1相关蛋白(WTAP)在缺氧/复氧(H/R)诱导的心肌细胞损伤中的调节作用及其分子机制。方法①实验一:将H9C2心肌细胞分为空白对照组和H/R模型组。采用H/R诱导H9C2细胞建立心肌缺血/再灌注(I/R)损伤模型;空白对照组不进行处理。采用N6-甲基腺苷(m6A)Rna甲基化测定试剂盒检测m6A水平;分别采用实时荧光定量聚合酶链反应(RT-qPCR)和蛋白质免疫印迹试验(Western blotting)检测甲基化转移酶〔WTAP、甲基转移酶样蛋白(mETTL3、mETTL14)〕的基因和蛋白表达水平。②实验二:将H9C2心肌细胞分为空白对照组、H/R+sh-NC组、H/R+sh-WTAP组。H/R+sh-WTAP组转染sh-WTAP以敲降WTAP表达,其余各组制模方法同实验一。转染48 h后,采用流式细胞术检测细胞凋亡率;采用Western blotting检测WTAP、活化天冬氨酸特异性半胱氨酸蛋白酶3(caspase-3)、活化多聚二磷酸腺苷酸核糖聚合酶(PARP)、转录激活因子4(ATF4)、蛋白激酶Rna样内质网激酶(PERK)、磷酸化PERK(p-PERK)和CCAAT/增强子结合蛋白同源蛋白(CHOP)的蛋白表达水平;采用免疫荧光染色观察ATF4阳性表达情况。③实验三:将H9C2心肌细胞分为空白对照组、H/R+sh-NC组、H/R+sh-WTAP和H/R+sh-WTAP+ATF4组。H/R+sh-WTAP+ATF4组用过表达质粒ATF4转染H9C2心肌细胞,其余各组制模方法同实验二。采用流式细胞术检测细胞凋亡率;采用Western blotting检测ATF4、CHOP、活化caspase-3和活化PARP的蛋白表达水平。结果①实验一:H/R模型组m6A甲基化水平较空白对照组显著上调。RT-qPCR检测结果显示,H/R模型组mETTL3、mETTL14和WTAP基因表达水平均较空白对照组显著上调,以WTAP上调最显著;Western blotting检测结果呈相同趋势。提示甲基化转移酶WTAP的表达水平在H/R诱导的心肌细胞中显著上调。②实验二:H/R+sh-WTAP组细胞凋亡水平较H/R+sh-NC组明显减少〔(14.16±1.58)%比(24.51±2.38)%,P<0.05〕。Western blotting检测结果显示,H/R+sh-WTAP组WTAP、活化caspase-3、活化PARP、p-PERK、ATF4和CHOP的蛋白表达水平均较H/R+sh-NC组显著下调。荧光显微镜下显示,H/R+sh-WTAP组ATF4阳性信号较H/R+sh-NC组显著减弱〔(19.36±1.81)%比(32.83±2.69)%,P<0.01〕。提示敲降WTAP可抑制H/R诱导的心肌细胞凋亡和内质网应激。③实验三:H/R+sh-WTAP+ATF4组细胞凋亡水平较H/R+sh-WTAP组显著增加〔(26.61±2.76)%比(17.14±0.87)%,P<0.05〕。Western blotting检测结果显示,H/R+sh-WTAP+ATF4组ATF4、CHOP、活化caspase-3和活化PARP的蛋白表达水平较H/R+sh-WTAP组显著上调。提示过表达ATF4可逆转sh-WTAP对H/R诱导的心肌细胞中内质网应激和细胞凋亡的抑制作用。结论甲基化转移酶WTAP可调节ATF4表达,介导细胞凋亡和内质网应激,促进H/R诱导的心肌细胞损伤。

关键词：甲基转移酶 Wilms肿瘤蛋白1相关蛋白细胞凋亡内质网应激缺氧/复氧

An Analysis of the Low moving Speed of Landfalling Typhoon In-Fa in 2021

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Journal of Tropical meteorology 2024年第1期30卷 51-60页

作者：郑丽娜吕新刚李瑞 Jinan meteorological Bureau of Shandong Province Jinan 250102 China

The movement speed of Typhoon In-Fa(2021)was notably slow,at 10 km h-1or less,for over 20 hours following its landfall in Zhejiang,China,in contrast to other typhoons that have made *** study examines the factors contributing to the slow movement of Typhoon In-Fa,including the steering flow,diabatic heating,vertical wind shear(VWS),and surface synoptic situation,by comparing it with Typhoons Yagi(2018)and Rumbia(2018)which followed similar *** findings reveal that the movement speed of Typhoons Yagi and Rumbia is most closely associated with their respective 500 h Pa environmental winds,with a steering flow of 10^(-12)m s^(-1).In contrast,Typhoon InFa’s movement speed is most strongly correlated with the 850 h Pa environmental wind field,with a steering flow speed of only 2 m s^(-1).Furthermore,as Typhoon In-Fa moves northwest after landfall,its intensity is slightly greater than that of Typhoons Yagi and Rumbia,and the pressure gradient in front of Typhoon In-Fa is notably smaller,leading to its slow ***,the precipitation distribution of Typhoon In-Fa differs from that of the other two typhoons,resulting in a weak asymmetry of wavenumber-1 diabatic heating,which indirectly affects its movement *** analysis indicates that VWS can alter the typhoon’s structure,weaken its intensity,and ultimately impact its movement.

关键词： landfalling typhoon steering flow diabatic heating VWS

Effects of Dietary Changes on the Gut microbiota of Cynops orientalis

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Asian Herpetological Research 2024年第2期15卷 63-72页

作者： Yuting WANG Yuning XIE Siyu WU Wenwen ZHANG Xiner CHENG Zixuan LI Fangfei HAN Jiayi SHI Yingying SHI Zhirong HE Chunna ZHANG Yixin JIANG na ZHAO Jiaqi LI Supen WANG College of Life Sciences Anhui Normal UniversityWuhu 241000AnhuiChina nanjing Institute of Environmental Sciences Ministry of Ecology and Environment of ChinaNanjing 210042JiangsuChina School of Ecology and Environment Anhui Normal UniversityWuhu 241002AnhuiChina Key Laboratory of Zoological Systematics and Evolution Institute of ZoologyChinese Academy of SciencesBeijing 100101China

The gut microbiota plays a pivotal role in the maintenance of health for amphibians,and it has been fully recognized,but the effectiveness of various influencing factors has not yet been fully *** this association should be considered while the amphibian order Caudata is facing a severe situation of population decline and extinction,there is little understanding of the association between diets and the diversity of gut microbiota in the amphibian order ***,we conducted an extensive analysis of the gut microbiota of Cynops orientalis fed different diets using functional prediction and 16S rRna amplicon sequencing ***,we found that wild individuals had greater gut microbial diversity and richness in comparison to captive ***,we identified the bacterial taxa associated with diets and observed differences in the relative abundance of gut microbiota among people on various ***,we have a predictive comprehension of the selection and adaptative significance of shared core ASVs in the gut microbiota in maintaining the healthy survival of *** in a large-scale spatiotemporal *** study emphasizes how diets alter the gut microbiota of Caudata and offers fresh perspectives on the conservation and captive management of species in Caudata.

关键词： 16S rRna Caudata core microbiota diet gut microbiota