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Surgical Science 2013年第2期4卷 131-134页

作者： Ross E. Willis Kent R. Van Sickle Richard m. peterson Department of Surgery University of Texas Health Science Center San Antonio USA Ross E. Willis

We ascertained the opinions of residents and faculty regarding technical skills decay during non-clinical training years and evaluated the effectiveness of a technical skills refresher curriculum (TSRC) offered to residents in the month prior to rejoining clinical training years. 32 faculty and 14 residents completed surveys which gleaned opinions regarding technical skills decay during non-clinical years. Six residents completed a TSRC during the month prior to rejoining clinical training. We compared clinical evaluations of the residents who completed the TSRC to residents who rejoined clinical training prior to the implementation of the curriculum. Surveys indicated that residents and faculty believe that non-clinical years have a slightly negative impact on technical skills and residents who completed dedicated research years would require up to 4 months for technical skills to return to the level of their non-research peers. Residents who completed the TSRC reported having significantly higher comfort levels with their technical skills after the curriculum

关键词： Technical Skills Decay Research Years Non-Clinical Years Surgical Education

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发展的机遇:中国、中亚和《能源宪章条约》

国际法研究 2016年第1期 16-38页

作者：淀川诏子亚历山大.m.彼特森苏苗罕日本西村朝日律师事务所美国华盛顿州最高法院中央财经大学法学院上海金融与法律研究院

随着中国—中亚天然气管道的建设和开通,中国正在深化与中亚国家之间的能源合作关系。在国际法上,《能源宪章条约》为能源合作提供了独特的多边法律框架。但是,与中亚国家不同,中国尚未成为《能源宪章条约》的缔约方。本文分析了中亚国... 详细信息

随着中国—中亚天然气管道的建设和开通,中国正在深化与中亚国家之间的能源合作关系。在国际法上,《能源宪章条约》为能源合作提供了独特的多边法律框架。但是,与中亚国家不同,中国尚未成为《能源宪章条约》的缔约方。本文分析了中亚国家油气资源运输协议的现状,接着对《能源宪章条约》及其在中亚国家的适用进行简要的概述。除了对中国加入《能源宪章条约》的成本效益进行分析以外,本文还分析了中亚的缔约国可能会因此获得的利益。最后,作者的结论是加入《能源宪章条约》符合中国的最佳利益,因为加入该条约是利大于弊的。

关键词：《能源宪章条约》贸易运输投资争端解决

Conceptual design of a 15-TW pulsed-power accelerator for high-energy-densityephysics experiments

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matter and Radiation at Extremes 2017年第4期2卷 204-223页

作者： R.B.Spielman D.H.Froula G.brent E.m.Campbell D.B.Reisman m.E.Savage m.J.Shoup III W.A.Stygar m.L.Wisher Laboratory for Laser Energetics University of RochesterRochesterNY14623USA Sandia National Laboratories AlbuquerqueNM 87185USA

We have developed a conceptual design of a 15-TW pulsed-power accelerator based on the linear-transformer-driver(LTD)architecture described by Stygar[*** et al.,*** *** 18,110401(2015)].The driver will allow multiple,high-energy-density experiments per day in a university environment and,at the same time,will enable both fundamental and integrated experiments that are scalable to larger *** this design,many individual energy storage units(bricks),each composed of two capacitors and one switch,directly drive the target load without additional pulse *** LTD modules in parallel drive the *** module consists of 16 LTD cavities connected in series,where each cavity is powered by 22 bricks connected in *** design stores up to 2.75 mJ and delivers up to 15 TW in 100 ns to the constant-impedance,water-insulated radial transmission *** transmission lines in turn deliver a peak current as high as 12.5 mA to the physics *** maximize its experimental value and flexibility,the accelerator is coupled to a modern,multibeam laser facility(four beams with up to 5 kJ in 10 ns and one beam with up to 2.6 kJ in 100 ps or less)that can provide auxiliary heating of the physics *** lasers also enable advanced diagnostic techniques such as X-ray Thomson scattering and multiframe and three-dimensional *** coupled accelerator-laser facility will be the first of its kind and be capable of conducting unprecedented high-energy-densityephysics experiments.

关键词： Pulsed power accelerator High energy density physics Conceptual design

Exogenous phosphatidic acid reduces acetaminophen-induced liver injury in mice by activating hepatic interleukin-6 signaling through inter-organ crosstalk

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Acta Pharmaceutica Sinica B 2021年第12期11卷 3836-3846页

作者： melissa m.Clemens Stefanie Kennon-mcGill Joel H.Vazquez Owen W.Stephens Erich A.peterson Donald J.Johann Felicia D.Allard Eric U.Yee Sandra SmcCullough Laura P.James Brian N.Finck mitchell R.mcGill Department of Pharmacology and Toxicology College of MedicineUniversity of Arkansas for Medical SciencesLittle RockAR 72205USA Interdisciplinary Graduate Program in Biomedical Sciences Graduate SchoolUniversity of Arkansas for Medical SciencesLittle RockAR 72205USA Department of Environmental and Occupational Health Fay W.Boozman College of Public HealthUniversity of Arkansas for Medical SciencesLittle RockAR 72205USA Winthrop P.Rockefeller Cancer Institute University of Arkansas for Medical SciencesLittle RockAR 72205USA Department of Pathology Renaissance School of MedicineStony Brook UniversityStony BrookNY 11794USA Department of Pediatrics College of MedicineUniversity of Arkansas for Medical SciencesLittle RockAR2205USA Division of Geriatrics and Nutritional Sciences Department of Internal MedicineWashington University School of MedicineSt.LouisMO 63110USA Center for Dietary Supplement Research University of Arkansas for Medical SciencesLittle RockAR 72205USA

We previously demonstrated that endogenous phosphatidic acid(PA)promotes liver regeneration after acetaminophen(APAP)***,we hypothesized that exogenous PA is also *** test that,we treated mice with a toxic APAP dose at 0 h,followed by PA or vehicle(Veh)*** then collected blood and liver at 6,24,and 52 ***-treatment with PA 2 h after APAP protected against liver injury at 6 h,and the combination of PA and N-acetyl-L-cysteine(NAC)reduced injury more than NAC ***,PA did not affect canonical mechanisms of APAP ***,transcriptomics revealed that PA activated interleukin-6(IL-6)signaling in the *** with that,serum IL-6 and hepatic signal transducer and activator of transcription 3(Stat3)phosphorylation increased in PA-treated ***,PA failed to protect against APAP in IL-6-deficient ***,IL-6 expression increased 18-fold in adipose tissue after PA,indicating that adipose is a source of PA-induced circulating ***,however,exogenous PA did not alter regeneration,despite the importance of endogenous PA in liver repair,possibly due to its short *** data demonstrate that exogenous PA is also beneficial in APAP toxicity and reinforce the protective effects of IL-6 in this model.

关键词： Acute liver injury Acute liver failure Adipokine Cytokine Dietary supplement Drug-induced liver injury Hepatotoxicity Lipid

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由三叶形纽结得到的三维流形的不变量

科学通报 1996年第21期41卷 1924-1930页

作者：李邦河李起升 Chariya peterson 中国科学院系统科学研究所河南大学数学系 Department.of mathematics Northwestern UniversityEvanstonIL 60206 USA

关于Witten不变量,已有不少研究,可参见文献[1～9].Freed和Gompf及Neil曾对若干三维流形Witten不变量τ_r(m)用计算机进行了近似的数值计算.本文给出所有由三叶结作整系数换球术得出的三维流形的不变量(?)_p(m,A)的计算公式(定理1),并... 详细信息

关于Witten不变量,已有不少研究,可参见文献[1～9].Freed和Gompf及Neil曾对若干三维流形Witten不变量τ_r(m)用计算机进行了近似的数值计算.本文给出所有由三叶结作整系数换球术得出的三维流形的不变量(?)_p(m,A)的计算公式(定理1),并通过计算机对p≤13进行符号计算,得到了几个有意思的结论.文中的记号是标准的,可参见文献[3,6,9],不另说明.若记L_n和R_n分别是由左手和右手标架为n的三叶结作换球术得到的三维流形,则L_(-n)和R_n是反向同胚的,于是(?)p(R_n,A)(?)(?)p(L_(-n),A),因此只需计算(?)p(Ln,A).记是m分支的标架全为零的链环,则有引理1〈e_(i_1),…,e_(i_m)〉k_m=e_(i_1)(λ_(i_2))…e_(i_(m-1))(λ_(i_m))〈e_(i_m)〉其中λ_j=-A^(2j+2)-A^(-2j-2).

关键词：纽结三维流形不变量流形三叶形纽结

反演南方海相层系热史动态演化的新温标——磷灰石、锆石(U-Th)/He年龄和封闭温度

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石油与天然气地质 2010年第3期31卷 277-287页

作者：秦建中王杰邱楠生 brent mcInnes 陶成中国石油化工股份有限公司石油勘探开发研究院无锡石油地质研究所中国石油大学(北京)油气资源与探测国家重点实验室 CSIRO Earth Science & Resource Engineering

对川东北普光一毛坝地区和通江地区的11个岩心和露头样品进行锆石、磷灰石（u—Th）／He定年分析，初步建立了He年龄一深度／温度动态演化模式，该地区磷灰石He封闭温度为85℃。川东北钻井岩心和剖面样品经历相同的热演化历程。该地区... 详细信息

对川东北普光一毛坝地区和通江地区的11个岩心和露头样品进行锆石、磷灰石（u—Th）／He定年分析，初步建立了He年龄一深度／温度动态演化模式，该地区磷灰石He封闭温度为85℃。川东北钻井岩心和剖面样品经历相同的热演化历程。该地区第三纪至第四纪为冷却抬升剥蚀主要时期，剥蚀速率约为74．8～172．5m／ma，剥蚀厚度大约为2800～3000m，地温逐渐降低到磷灰石He封闭温度，直至达到现今温度，与青藏高原隆升引发的新构造运动在四川盆地的响应有关。普光5井等3200m以上中生界样品未经历过锆石He封闭温度，可能只有3200m以下的样品经历锆石He封闭温度，但所有样品都经历了磷灰石He封闭温度。根据锆石（U—Th）／He年龄大致推算出，川东北地区可能在晚侏罗世开始抬升，在晚侏罗世一早白垩世期间普光一毛坝地区和通江地区都处于缓慢抬升剥蚀阶段，只是普光一毛坝地区抬升剥蚀开始时间要早于通江地区。磷灰石和锆石He封闭温度和年龄揭示了该区动态热演化历史。该区在178．0ma之前古地温大于170～1900C，随后地层继续抬升，古地温下降；在40．5～178．0ma时，古地温为85—170℃；在0～40．5ma时，现今地温小于85℃。

关键词： (U—Th)/He年龄封闭温度抬升剥蚀热史动态演化热史模拟南方海相层系

Large-Scale Fluidization Features from Late Holocene Coseismic Paleoliquefaction in the Willamette River Forearc Valley, Central Cascadia Subduction Zone, Oregon, USA

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Open Journal of Earthquake Research 2014年第2期3卷 82-99页

作者： Curt D. peterson Kurt Kristensen Rick minor Evergreen School Hillsboro USA Heritage Research Associates Eugene USA Portland State University Portland USA

A search of Willamette River cutbanks was conducted for the presence of late Holocene paleoli-quefaction records in the Willamette forearc valley, located 175 ± 25 km landward from the buried trench in the central Cascadia subduction zone. Eight cutbank sites are reported that show evidence of large-scale fluidization features (≥10 cm width) including clastic sand dikes and intruded sand sills in Holocene overbank mud deposits. The targeted alluvial sequences, and hosted paleoliquefaction records, are of late Holocene age, as based on radiocarbon dating, flood silt thickness (≤4 m thickness), and minimal consolidation of dike sand (~1.5 ± 0.5 kg·cm-2 unconfined compressive strength). Two of the paleoliquefaction sites, which are separated by 150 km distance, overlap in age (175 - 500 yr BP) with the last great megathrust rupture (mw 8.5 - 9.0) in the Cascadia margin, dated at AD 1700. The scarcity of exposed late Holocene paleoliquefaction sites in the Willamette River cutbanks motivated subsurface searches for thick basal sand deposits and overlying fluidization features, using floodplain geomorphological analyses, ground penetrating radar, and remote pole-camera scans of deep trench walls (3 - 4 m depth). The onset of large-scale fluidization features occurred in overbank mud deposits (2 - 3 m thickness) above unconsolidated sand bodies (≥2 m thickness) with unconfined compressive strengths of ~1.5 ± 0.5 kg·cm-2. We recommend geomorphically-targeted subsurface explorations rather than traditional cutbank searches for evidence of coseismic paleoliquefaction in high-gradient river valley systems.

关键词： Paleoliquefaction Clastic Dike Late Holocene Cascadia Subduction Zone

Decline in a Tilletia indica Teliospore Population in a Naturally Infested Arizona (USA) Wheat Field

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American Journal of Plant Sciences 2017年第11期8卷 2622-2634页

作者： Gary L. peterson Kathleen L. Kosta USDA ARS Foreign Disease-Weed Science Research Unit Fort Detrick USA California Department of Food and Agriculture Sacramento USA

Following a 2004-outbreak of Karnal bunt in an Arizona wheat field where infection had not been detected in recent years, the population and viability of Tilletia indica teliospores in surface and subsurface layers of soil were monitored over a four-year period. The field was seeded with two parallel 1.8 m × 190 m strips of wheat, 11 m apart and the remainder planted in non-host barley. Thirty-eight 1.22 m2 wheat plots were harvested and seed examined for infection. Several times throughout each season soil samples were taken from each of 25 points throughout the field. Teliospores extracted from subsamples of each soil sample were examined to estimate the number of teliospores per gram soil and germination percentage. The average (SD) infection observed for each of the four consecutive seasons was 7.05 (4.6), 2.89 (5.5), 0, and 0.004% (0). The average number of teliospores recovered per gram of soil during the first sampling was 36 and 39 for the 0.5 cm deep (surface) and 5.5 cm deep (subsurface), respectively, with an average teliospore germination of 29%. By the last season, the average numbers of teliospores recovered were 5 and 2.5 per gram of soil, respectively, with an average germination of 1.0%.

关键词： Karnal Bunt Soil Survival Teliospore Recovery

Quetiapine augmentation of prolonged exposure therapy in veterans with PTSD and a history of mild traumatic brain injury: design and methodology of a pilot study

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military medical Research 2021年第1期8卷 121-131页

作者： muhammad R.Baig Robert D.Beck Jennifer L.Wilson Jennifer A.Lemmer Adeel meraj Eric C.meyer Jim mintz Alan L.peterson John D.Roache mental Health South Texas Veterans Healthcare System116 A7400 Merton Minter BIvdSan AntonioTX 78229USA Polytrauma Rehabilitation Center South Texas Veterans Healthcare SystemSan AntonioTXUSA Department of Psychiatry and Behavioral Sciences University of Texas Health Science Center at San AntonioSan AntonioTXUSA Department of Veterans Affairs VISN 17 Center of Excellence for Research on Returning War Veterans WacoTXUSA Central Texas Veterans Healthcare System WacoTXUSA Department of Psychology and Neuroscience Baylor UniversityWacoTXUSA Department of Epidemiology and Biostatistics University of Texas Health Science Center at San AntonioSan AntonioTXUSA Department of Psychology University of Texas at San AntonioSan AntonioUSA Department of Pharmacology University of Texas Health Science Center at San AntonioSan AntonioTXUSA

Background: Selective serotonergic reuptake inhibitors(SSRIs) are first-line pharmacologic treatments for patients with posttraumatic stress disorder(PTSD), but must be given over extended period of time before the onset of action. The use of SSRIs in PTSD patients with mild traumatic brain injury(m TBI) is problematic since SSRIs could exacerbate post-concussion syndrome(PCS) symptoms. VA/DOD guidelines identify trauma-focused psychotherapy as the best evidence-based treatment for PTSD, but overall effectiveness is limited by reduced levels of patient engagement and retention. A previous study from this research group suggested that quetiapine monotherapy, but not risperidone or valproate, could increase engagement in trauma-focused ***: We report the study protocol of a pilot study funded under the South-Central mental Illness Research, Education, and Clinical Center pilot study program from the U.S. Department of Veterans Affairs. This randomized, open-label study was designed to evaluate the feasibility of completing a randomized trial of quetiapine vs. treatment as usual to promote patient engagement in PTSD patients with a history of m ***: We expect that the success of this ongoing study should provide us with the preliminary data necessary to design a full-scale randomized trial. Positive efficacy results in a full-scale trial should inform new VA guidelines for clinical practice by showing that quetiapine-related improvements in patient engagement and retention may be the most effective approach to assure that VA resources achieve the best possible outcome for *** registration: NCT04280965.

关键词： Quetiapine Trauma-focused psychotherapy Posttraumatic stress disorder mild traumatic brain injury Veterans

双侧肾上腺切除狗促肾上腺皮质激素释放因子(CRF)免疫组织化学研究

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神经解剖学杂志 1987年第1期 122-122页

作者：马丽云 A.E.Zimmerman m.peterson 天津市内分泌研究所天津医学院同位素室美国俄勒冈医科大学神经系美国动物研究中心美国纽约

双侧肾上腺切除狗4只,存活四周。正常对照狗5只。经灌流、固定、取脑,震动切片机切片厚60μm。免疫组化ABC法染色。光镜观察。结果:双侧肾上腺切除狗与正常对照狗的下丘脑室旁核内测部均可见有聚集的CRF免疫反应阳性细胞及纤维、双测肾... 详细信息

双侧肾上腺切除狗4只,存活四周。正常对照狗5只。经灌流、固定、取脑,震动切片机切片厚60μm。免疫组化ABC法染色。光镜观察。结果:双侧肾上腺切除狗与正常对照狗的下丘脑室旁核内测部均可见有聚集的CRF免疫反应阳性细胞及纤维、双测肾上腺切除者,细胞数目比对照者明显增多,为对照组的4.3倍(平均值分别为5061及1175个)。统计学处理后P<0.05,有显著性差别。

关键词：双侧肾上腺切除显著性差别免疫组化ABC法下丘脑室旁核细胞数目免疫反应免疫组织化学正常对照