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Athermal third harmonic generation in micro‐ring resonators

Opto-Electronic Advances 2020年第12期3卷 17-27页

作者： Shaohao Wang Yuhua li brent Elittle leiran Wang Xiang Wang Roy RDavidson Sai Tak Chu FZU-Jinjiang Joint Institute of Microelectronics Jinjiang Science and Education ParkFuzhou UniversityJinjiang 362200China Department of Physics City University of Hong KongKowloon TongHong Kong 999077China State Key laboratory of Transient Optics and Photonics Xi’an Institute of Optics and Precision MechanicsChinese Academy of SciencesXi’an 710119China University of Chinese Academy of Sciences Beijing 100049China QXP Technology Xi’an 710311China Department of Microelectronics Science and Technology Qi Shan CampusFuzhou UniversityFuzhou 350108China Key laboratory of Optical Field Manipulation of Zhejiang Province Department of PhysicsZhejiang Sci-Tech UniversityHangzhou 310018China

Nonlinear high-harmonic generation in micro-resonators is a common technique used to extend the operating range of applications such as self-referencing systems and coherent communications in the visible ***,the generated high-harmonic emissions are subject to a resonance shift with a change in *** present a comprehensive study of the thermal behavior induced phase mismatch that shows this resonance shift can be compensated by a combination of the linear and nonlinear thermo-optics *** this model,we predict and experimentally demonstrate visible third harmonic modes having temperature dependent wavelength shifts between−2.84 pm/ºC and 2.35 pm/ºC when pumped at the *** providing a new way to achieve athermal operation,this also allows one to measure the thermal coefficients and Q-factor of the visible *** steady state analysis,we have also identified the existence of stable athermal third harmonic generation and experimentally demonstrated orthogonally pumped visible third harmonic modes with a temperature dependent wavelength shift of 0.05 pm/ºC over a temperature range of 12º*** findings promise a configurable and active temperature dependent wavelength shift compensation scheme for highly efficient and precise visible emission generation for potential 2f–3f self-referencing in metrology,biological and chemical sensing applications.

关键词： third-harmonic generation thermodynamics micro-resonators

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Conceptual design of a 15-TW pulsed-power accelerator for high-energy-densityephysics experiments

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Matter and Radiation at Extremes 2017年第4期2卷 204-223页

作者： R.B.Spielman D.H.Froula G.brent E.M.Campbell D.B.Reisman M.E.Savage M.J.Shoup III W.A.Stygar M.l.Wisher laboratory for laser Energetics University of RochesterRochesterNY14623USA Sandia National laboratories AlbuquerqueNM 87185USA

We have developed a conceptual design of a 15-TW pulsed-power accelerator based on the linear-transformer-driver(lTD)architecture described by Stygar[*** et al.,*** *** 18,110401(2015)].The driver will allow multiple,high-energy-density experiments per day in a university environment and,at the same time,will enable both fundamental and integrated experiments that are scalable to larger *** this design,many individual energy storage units(bricks),each composed of two capacitors and one switch,directly drive the target load without additional pulse *** lTD modules in parallel drive the *** module consists of 16 lTD cavities connected in series,where each cavity is powered by 22 bricks connected in *** design stores up to 2.75 MJ and delivers up to 15 TW in 100 ns to the constant-impedance,water-insulated radial transmission *** transmission lines in turn deliver a peak current as high as 12.5 MA to the physics *** maximize its experimental value and flexibility,the accelerator is coupled to a modern,multibeam laser facility(four beams with up to 5 kJ in 10 ns and one beam with up to 2.6 kJ in 100 ps or less)that can provide auxiliary heating of the physics *** lasers also enable advanced diagnostic techniques such as X-ray Thomson scattering and multiframe and three-dimensional *** coupled accelerator-laser facility will be the first of its kind and be capable of conducting unprecedented high-energy-densityephysics experiments.

关键词： Pulsed power accelerator High energy density physics Conceptual design

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Effects of transdermal magnesium chloride on quality of life for patients with fibromyalgia: a feasibility study

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Journal of Integrative Medicine 2015年第5期13卷 306-313页

作者： Deborah J.Engen Samantha J.Mc Allister Mary O.Whipple Stephen S.Cha liza J.Dion Ann Vincent brent A.Bauer Dietlind l.Wahner-Roedler Department of Physical Medicine and Rehabilitation Mayo Clinic Division of General Internal Medicine Mayo Clinic Division of Biomedical Statistics and Informatics Mayo Clinic

BACKGROUND： Fibromyalgia is a syndrome characterized by chronic pain, fatigue, depression, and sleep disturbances. Its primary cause is unclear. Several studies have reported decreased intracellular magnesium levels in patients with fibromyalgia and have found negative correlation between magnesium levels and fibromyalgia symptoms.OBJECTIVE： To gather preliminary data on whether transdermal magnesium can improve quality of life for women who have fibromyalgia. DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS： This is a patient questionnaires and survey in a fibremyalgia clinic at a tertiary medical center. Forty female patients with the diagnosis of fibremyalgia were enrolled. Each participant was provided a spray bottle containing a transdermal magnesium chloride solution and asked to apply 4 sprays per limb twice daily for 4 weeks. Participants were asked to complete the Revised Fibromyalgia Impact Questionnaire, SF-36v2 Health Survey, and a quality-of-life analog scale at baseline, week 2, and week 4. MAIN OUTCOME MEASURE： Questionnaire and survey scores, evaluated through intent-to-treat and per-protocol analyses. RESUlTS： Twenty-four patients completed the study （mean [SD] age, 57.2 [7.6] years; white, 95%; mean body mass index, 31.3 kg/m2）. With intention-to-treat analysis, Revised Fibromyalgia Impact Questionnaire subscale and total scores were significantly improved at week 2 and week 4 （total score, P = 0.001）. Per-protocol analysis results were similar： all subscales of the Revised Fibremyalgia Impact Questionnaire were significantly improved at week 2 and week 4 （total score, P = 0.001）. CONClUSION： This pilot study suggests that transdermal magnesium chloride applied on upper and lower limbs may be beneficial to patients with fibromyalgia.

关键词： fibromyalgia magnesium chloride Revised Fibromyalgia Impact Questionnaire clinical trial

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When will it end? long-lived intracontinental reactivation in central Australia

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Geoscience Frontiers 2019年第1期10卷 149-164页

作者： Raphael Quentin de Gromard Christopher l.Kirkland Heather M.Howard Michael T.D.Wingate Fred Jourdan brent I.A.Mc Innes Martin Danisik Noreen J.Evans Bradley J.McDonald R.Hugh Smithies Geological Survey of Western Australia Department of Mines Industry Regulation and Safety School of Earth and Planetary Science/John de laeter Centre/TIGeR Curtin University

The post-Mesoproterozoic tectonometamorphic history of the Musgrave Province, central Australia, has previously been solely attributed to intracontinental compressional deformation during the 580 -520 Ma Petermann Orogeny. However, our new structurally controlled multi-mineral geochronology results,from two north-trending transects, indicate protracted reactivation of the Australian continental interior over ca. 715 million years. The earliest events are identified in the hinterland of the orogen along the western transect. The first tectonothermal event, at ca. 715 Ma, is indicated by40 Ar/39 Ar muscovite and U e Pb titanite ages. Another previously unrecognised tectonometamorphic event is dated at ca. 630 Ma by Ue Pb analyses of metamorphic zircon rims. This event was followed by continuous cooling and exhumation of the hinterland and core of the orogen along numerous faults, including the Woodroffe Thrust,from ca. 625 Ma to 565 Ma as indicated by muscovite, biotite, and hornblende40 Ar/39 Ar cooling ages. We therefore propose that the Petermann Orogeny commenced as early as ca. 630 Ma. Along the eastern transect,40 Ar/39 Ar muscovite and zircon(Ue Th)/He data indicate exhumation of the foreland fold and thrust system to shallow crustal levels between ca. 550 Ma and 520 Ma, while the core of the orogen was undergoing exhumation to mid-crustal levels and cooling below 600-660℃. Subsequent cooling to 150 -220℃ of the core of the orogen occurred between ca. 480 Ma and 400 Ma(zircon [Ue Th]/He data)during reactivation of the Woodroffe Thrust, coincident with the 450 -300 Ma Alice Springs *** of the footwall of the Woodroffe Thrust to shallow depths occurred at ca. 200 Ma. More recent tectonic activity is also evident as on the 21 May, 2016(Sydney date), a magnitude 6.1 earthquake occurred, and the resolved focal mechanism indicates that compressive stress and exhumation along the Woodroffe Thrust is continuing to the present day. Overall, these results

关键词： Intracontinental deformation Thermochronology Petermann orogen Musgrave Province Plate tectonics Cratonization

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Cryo-EM structure of the plant 26S proteasome

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Plant Communications 2022年第3期3卷 116-126页

作者： Susanne Kandolf Irina Grishkovskaya Katarina Belacic Derek l.Bolhuis Sascha Amann brent Foster Richard Imre Karl Mechtler Alexander Schleiffer Hemant D.Tagare Ellen D.Zhong Anton Meinhart Nicholas G.Brown David Haselbach Research Institute of Molecular Pathology(IMP) Vienna BioCenter(VBC)Campus-Vienna-BioCenter 11030 ViennaAustria Department of Radiology and Biomedical Imaging Yale UniversityNew HavenCT 06510USA Department of Pharmacology and lineberger Comprehensive Cancer Center University of North Carolina School of MedicineChapel HillNC 27599USA Computer Science and Artificial Intelligence laboratory Massachusetts Institute of TechnologyCambridgeMA 02139USA Vienna BioCenter PhD Program Doctoral School of the University at Vienna and Medical University of ViennaVienna BioCenter(VBC)ViennaAustria Institute of Physical Chemistry University of FreiburgAlbertstraße 21Freiburg 79104Germany CIBSS Centre for Integrative Biological Signalling Studies University of FreiburgFreiburgGermany

Targeted proteolysis is a hallmark of *** is especially important in long-lived cells that can be found in higher eukaryotes,like *** task is mainly fulfilled by the ubiquitin–proteasome ***,proteolysis by the 26S proteasome is vital to development,immunity,and cell *** the yeast and animal proteasomes are well characterized,there is only limited information on the plant *** determined the first plant 26S proteasome structure from Spinacia oleracea by single-particle electron cryogenic microscopy at an overall resolution of 3.3 A°.We found an almost identical overall architecture of the spinach proteasome compared with the known structures from mammals and ***,we noticed a structural difference in the proteolytic active b1 ***,we uncovered an unseen compression state by characterizing the proteasome’s conformational *** suspect that this new conformation of the 20S core protease,in correlation with a partial opening of the unoccupied gate,may contribute to peptide release after *** data provide a structural basis for the plant proteasome,which is crucial for further studies.

关键词： 26S proteasome spinach UPS cryo-EM conformational landscape

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Photonic radio frequency channelizers based on Kerr optical micro-combs

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Journal of Semiconductors 2021年第4期42卷 17-32页

作者： Mengxi Tan Xingyuan Xu Jiayang Wu Thach G.Nguyen Sai T.Chu brent E.little Roberto Morandotti Arnan Mitchell David J.Moss Optical Sciences Centre Swinburne University of TechnologyHawthornVIC 3122Australia Electro-Photonics laboratory Department of Electrical and Computer Systems EngineeringMonash UniversityVIC3800Australia School of Engineering RMIT UniversityMelbourneVIC 3001Australia Department of Physics City University of Hong KongHong KongChina State Key laboratory of Transient Optics and Photonics Xi'an Institute of Optics and Precision MechanicsChinese Academy of ScienceXi'an 710119China INRS-Énergie Matériaux et Télécommunications1650 Boulevard Lionel-BouletVarennesQuébecJ3X 1S2Canada Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 610054China

We review recent work on broadband RF channelizers based on integrated optical frequency Kerr micro-combs combined with passive micro-ring resonator filters,with microcombs having channel spacings of 200 and 49 *** approach to realizing RF channelizers offers reduced complexity,size,and potential cost for a wide range of applications to microwave signal detection.

关键词： microwave photonic signal channelization integrated optical frequency comb

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Orthogonally polarized RF optical single sideband generation with integrated ring resonators

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Journal of Semiconductors 2021年第4期42卷 53-66页

作者： Mengxi Tan Xingyuan Xu Jiayang Wu Thach G.Nguyen Sai T.Chu brent E.little Arnan Mitchell Roberto Morandotti David J.Moss Optical Sciences Centre Swinburne University of TechnologyHawthornVIC 3122Australia Electro-Photonics laboratory Department of Electrical and Computer Systems EngineeringMonash UniversityVIC3800Australia School of Engineering RMIT UniversityMelbourneVIC 3001Australia Department of Physics City University of Hong KongHong KongChina State Key laboratory of Transient Optics and Photonics Xi'an Institute of Optics and Precision MechanicsChinese Academy of ScienceXi'an 710119China INRS-Énergie Matériaux et Télécommunications1650 Boulevard Lionel-BouletVarennesQuébecJ3X 1S2Canada Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 610054China

We review recent work on narrowband orthogonally polarized optical RF single sideband generators as well as dualchannel equalization,both based on high-Q integrated ring *** devices operate in the optical telecommunications C-band and enable RF operation over a range of either fixed or thermally tuneable *** operate via TE/TM mode birefringence in the *** achieve a very large dynamic tuning range of over 55 dB for both the optical carrier-to-sideband ratio and the dual-channel RF equalization for both the fixed and tunable devices.

关键词： microwave photonics micro-ring resonators radio frequency

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实验移植总结

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中华器官移植杂志 1986年第2期7卷 87-88页

作者： l.brent 夏五一

第十届国际器官移植学术会议是最近一次大规模的器官移植专业会议,于1984年10月在美国明尼苏达州召开。其主要论文收集在1985年第7卷第1期的《移植汇编(Transplantation Proceeding)》中,其中三篇总结对器官移植三个主要方面:免疫生物... 详细信息

第十届国际器官移植学术会议是最近一次大规模的器官移植专业会议,于1984年10月在美国明尼苏达州召开。其主要论文收集在1985年第7卷第1期的《移植汇编(Transplantation Proceeding)》中,其中三篇总结对器官移植三个主要方面:免疫生物学、实验移植与临床移植作了精练的概述,从中可以看到器官移植的近况和发展的新趋势。故特予以摘要译出,以供本刊读者参考。

关键词：实验移植

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重要的考试

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英语自学 2009年第6期 9-12页

作者： brent l.Cobb 李威

小时候，我一直都认为能够帮助孩子制作松木赛车才能体现做父亲的价值，但是，我的看法可能是错误的。在我12岁的时候，我的父亲就去世了。因此，帮助我制作松木赛车成了他所面对的身为人父的最大的也是最后的考试。我非常清楚地记得父... 详细信息

小时候，我一直都认为能够帮助孩子制作松木赛车才能体现做父亲的价值，但是，我的看法可能是错误的。在我12岁的时候，我的父亲就去世了。因此，帮助我制作松木赛车成了他所面对的身为人父的最大的也是最后的考试。我非常清楚地记得父亲是如何通过他的制作松木赛车考试的，我也知道，早晚有一天我也不得不接受同样的考试。

关键词：考试父亲赛车松木制作

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鸡传染性贫血病毒的分离鉴定

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国外兽医学（畜禽传染病） 1992年第4期12卷 12-14页

作者： brent.,l 周武林

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