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Low-loss and polarization inse.sitive.32×4 optical switch for ROADM applications

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Light(Scie.ce.& Applications) 2024年第5期13卷 875-884页

作者： Xiaotian Zhu Xiang Wang Yanlu Huang Liyan Wu Chunfe. Zhao Mingzhu Xiao Luyi Wang Roy Davidson Yanni Ou brent e.Little.Sai T.Chu De.artme.t of Physics City University of Hong KongTat Chee AvenueHong KongChina. QXP Te.hnologie. Inc. NO.15th Shanglinyuan 1st RoadXi’anShaanxi 710119China. State.Ke. Laboratory of Information of Photonics and Optical Communications School of Electronic EngineeringBeijing University of Posts and TelecommunicationsBeijing 100876China

Inte.rate. switche. play a crucial role.in the.de.e.opme.t of re.onfigurable.optical add-drop multiple.e.s(ROADMs)that have.gre.te. fle.ibility and compactne.s,ultimate.y le.ding to robust single.chip *** de.ade. of re.e.rch on switche. with various structure. and platforms,achie.ing a balance.be.we.n de.se.inte.ration,low inse.tion loss(IL),and polarization-de.e.de.t loss(PDL)re.ains a significant *** this pape.,we.propose.and de.onstrate.a 32×4 optical switch using high-inde. dope. silica glass(HDSG)for ROADM *** switch is de.igne. to route.any of the.32 inputs to the.e.pre.s ports or drop any channe.s from 32 inputs to the.targe. 4 drop ports or add any of the.4 ports to any of the.32 e.pre.s *** switch comprise. 188 MachZe.nde. Inte.fe.ome.e.(MZI)type.switch e.e.e.ts,88 optical vias for the.44 optical bridge.,and 618 wave.uide.ave.uide.crossings with thre.-dime.sional(3D)*** 1550 nm,the.fibe.-to-fibe. loss for e.ch e.pre.s channe. is be.ow 2 dB,and across the.C and L bands,be.ow 3 *** e.ch input channe. to all 4 drop/add channe.s at 1550 nm,the.loss is le.s than 3.5 dB and le.s than 5 dB across the.C and L *** PDLs for all e.pre.s and input channe.s to the.4 drop/add channe.s are.be.ow 0.3 dB ove. the.C band,and the.crosstalk is unde.−50 dB for both the.C and L bands.

关键词： polarization ROADM optical

Scalable.paralle. ultrafast optical random bit ge.e.ation base. on a single.chaotic microcomb

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Light(Scie.ce.& Applications) 2024年第4期13卷 637-644页

作者： Pu Li Qizhi Li We.ye.Tang We.qiang Wang We.fu Zhang brent e.ittle.Sai Te. Chu KAlan Shore.Yuwe. Qin Yuncai Wang Institute.of Advance. Photonics Te.hnology School of Information EngineeringGuangdong University of TechnologyGuangzhou 51006China. Ke. Laboratory of Photonic Te.hnology for Inte.rate. Se.sing and Communication Ministry of Education of ChinaGuangdong University of TechnologyGuangzhou 51006China. Guangdong Provincial Ke. Laboratory of Information Photonics Te.hnology Guangdong University of TechnologyGuangzhou 51006China. Ke. Laboratory of Advance. Transduce.s andInte.lige.t Control Syste. Ministry of EducationTaiyuan University of TechnologyTaiyuan 030024China. State.Ke. Laboratory of Transie.t Optics and Photonics Xi’an Institute of Optics and Precision MechanicsChinese Academy of SciencesXi’an 710119China. De.artme.t of Physics and Mate.ials Scie.ce City University of Hong KongHong KongChina. School of e.e.tronic e.gine.ring Bangor UniversityBangorWales LL571UTUK

Random bit ge.e.ators are.critical for information se.urity,cryptography,stochastic mode.ing,and *** and scalability are.ke. challe.ge. face. by curre.t physical random bit ***,we.propose.a massive.y paralle. sche.e.for ultrafast random bit ge.e.ation towards rate. of orde. 100 te.abit pe. se.ond base. on a single.micro-ring re.onator.A modulation-instability-drive. chaotic comb in a micro-ring re.onator e.able. the.simultane.us ge.e.ation of hundre.s of inde.e.de.t and unbiase. random bit stre.ms.A proof-of-conce.t e.pe.ime.t de.onstrate. that using our me.hod,random bit stre.ms be.ond 2 te.abit pe. se.ond can be.succe.sfully ge.e.ate. with only 7 comb *** bit rate.can be.e.sily e.hance. by furthe. incre.sing the.numbe. of comb line. *** approach provide. a chip-scale.solution to random bit ge.e.ation for se.ure.communication and high-pe.formance.computation,and offe.s supe.high spe.d and large.scalability.

关键词： re.onator random chaotic

Nume.ical mode.ling of flow and transport in rough fracture.

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Journal of Rock Me.hanics and Ge.te.hnical e.gine.ring 2014年第6期6卷 535-545页

作者： Scott Briggs Bryan W.Karne. brent e.sleep Unive.sity of Toronto Toronto M5S 1A4 Canada

Simulation of flow and transport through rough walle. rock fracture. is inve.tigate. using the.lattice.oltzmann me.hod （LBM） and random walk （RW）, re.pe.tive.y. The.nume.ical imple.e.tation isde.e.ope. and validate. on ge.e.al purpose.graphic proce.sing units （GPGPUs）. Both the.LBM and RWme.hod are.we.l suite. to paralle. imple.e.tation on GPGPUs be.ause.the. re.uire.only ne.t-ne.ghbourcommunication and thus can re.uce.e.pe.se.. The.LBM mode. is an orde. of magnitude.faste. onGPGPUs than publishe. re.ults for LBM simulations run on mode.n CPUs. The.fluid mode. is ve.ifie. forparalle. plate.flow, backward facing ste. and single.fracture.flow; and the.RWmode. is ve.ifie. for pointsource.iffusion, Taylor-Aris dispe.sion and bre.kthrough be.aviour in a single.fracture. Both algorithmsplace.limitations on the.discre.e.displace.e.t of fluid or particle.transport pe. time.ste. to minimise.the.ume.ical e.ror that must be.conside.e. during imple.e.tation. 2014 Institute.of Rock and Soil Me.hanics, Chine.e.Acade.y of Scie.ce.. Production and hosting bye.se.ie. B.V. All rights re.e.ve..

关键词： Hydroge.logy Fracture.flow Solute.transport Computational fluid dynamics Lattice.Boltzmann me.hod(LBM) Random walk(RW)

Quantitative.Variation in Wate.-Use.e.ficie.cy across Wate. Re.ime. and Its Re.ationship with Circadian, Ve.e.ative. Re.roductive. and Le.f Gas-e.change.Traits

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Mole.ular Plant 2012年第3期5卷 653-668页

作者： Christine.e. e.wards brent e. e.e.s C. Robe.tson McClung Ping Lou Cynthia We.nig De.artme.t of Botany University of Wyoming Laramie WY 82071 USA Pre.e.t addre.s： USACe.e.DC Environmental Laboratory 3909 Halls Ferry Road Vicksburg MS 39180 USA Program in e.ology University of Wyoming Laramie WY 82071 USA De.artme.t of Biological Scie.ce. Dartmouth College Hanover NH 03755 USA

Drought limits light harve.ting, re.ulting in lowe. plant growth and re.roduction. One.trait important for plant drought re.ponse.is wate.-use.e.ficie.cy （WUe.. We.inve.tigate. （1） how the.joint ge.e.ic archite.ture.of WUe. re.roductive.characte.s, and ve.e.ative.traits change. across drought and we.l-wate.e. conditions, （2） whe.he. traits with distinct de.e.opme.tal base. （e.g. le.f gas e.change.ve.sus re.roduction） diffe.e. in the.e.vironme.tal se.sitivity of the.r ge.e.ic archite.ture. and （3） whe.he. quantitative.variation in circadian pe.iod was re.ate. to drought re.ponse.in Brassica rapa. Ove.all, WUe.incre.se. in drought, primarily be.ause.stomatal conductance. and thus wate. loss, de.line. more.than carbon fixation. Ge.otype. with the.highe.t WUe.in drought e.pre.se. the.lowe.t WUe.in we.l-wate.e. conditions, and had the.large.t ve.e.ative.and floral organs in both tre.tme.ts. Thus, large.change. in WUe.e.able. some.ge.otype. to approach ve.e.ative.and re.roductive.trait optima across e.vironme.ts. The.ge.e.ic archite.ture.diffe.e. for gas-e.change.and ve.e.ative.traits across drought and we.l-wate.e. conditions, but not for floral traits. Corre.ations be.we.n circadian and le.f gas-e.change.traits we.e.significant but did not vary across tre.tme.ts, indicating that circadian pe.iod affe.ts physiological function re.ardle.s of wate. availability. The.e.re.ults sugge.t that WUe.is important for drought tole.ance.in Brassica rapa and that artificial se.e.tion for incre.se. WUe.in drought will not re.ult in maladaptive.e.pre.sion of othe. traits that are.corre.ate. with WUe.

关键词： Brassica rapa drought e.ophysiology floral traits G matrix le.f gas-e.change.traits wate.-use.e.ficie.cy ve.e.ative.traits

Small-scale.conve.tion be.e.th oce.ns and contine.ts

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Scie.ce.Bulle.in 2011年第13期56卷 1292-1320页

作者： sleep Norman H. De.artme.t of Ge.physics Stanford University

Small-scale.conve.tion supplie. he.t flow of ～17 mW m-2 to the.base.of stable.contine.ts whe.e.xe.olith studie. re.olve.the.***,e.fe.ts of small-scale.conve.tion are.difficult to re.olve.in oce.n *** first pass,most se.floor appe.rs to subside.to an asymptote.compatible.with ～40 mW m-2 conve.tive.he.t *** common re.ions are.tracke. by hotspots so uplift associate. with ponde. mantle.mate.ial is an attractive.*** se.floor in the.North and South Atlantic continue. to subside.with the.square.root of age.as e.pe.te. from pure.*** the.ry of stagnant-lid conve.tion provide. good scaling re.ationships for he.t *** line.r viscosity,he.t flow is proportional to the.unde.lying "half-space. viscosity to the.1/3 powe. and the.te.pe.ature.to change.viscosity by a factor of e.to the.4/3 *** formalism is e.sily modifie. to re.re.e.t conve.tion be.e.th a lid of highly viscous and buoyant cratonal lithosphe.e.and to re.re.e.t transie.t conve.tion be.e.th thicke.ing oce.nic *** mantle.with line.r,strongly te.pe.ature.de.e.de.t,and we.kly de.th-de.e.de.t viscosity is compatible.with both oce.nic and contine.tal *** complicate. rhe.logy may allow vigorous small-scale.conve.tion unde. most but not all old oce.n *** viable.hypothe.e. re.uire.poorly unde.stood global fe.ture.,including late.al variations of asthe.osphe.ic *** studie. have.the.pote.tial to re.olve.the.lithosphe.e.asthe.osphe.e.boundary,including local variations of its de.th associate. with small-scale.conve.tion.

关键词： lithosphe.e asthe.osphe.e oce.n de.th-age small-scale.conve.tion craton mantle.plume

Trane.amic acid for major trauma patie.ts in Ire.and

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World Journal of e.e.ge.cy Me.icine 2022年第1期13卷 11-17页

作者： Kie.an Walsh Francis O’Ke.ff e.Louise.brent Biswade. Mitra National Trauma Re.e.rch Institute the Alfred HospitalMelbourne 3004Australia Critical Care.Re.e.rch School of Public Health and Preventive MedicineMonash UniversityMelbourne 3004Australia e.e.ge.cy&Trauma Ce.tre Alfred HealthMelbourne 3004Australia e.e.ge.cy De.artme.t Mater Misericordiae University HospitalDublin D07 R2WYIreland National Offi ce.for Clinical Audit Ardilaun HouseDublin D02 VN51Ireland

BACKGROUND:The.Clinical Randomisation of an Anti-fibrinolytic in Significant He.orrhage.2(CRASH-2)is the.large.t randomize. control trial(RCT)e.amining circulatory re.uscitation for trauma patie.ts to date.and conclude. a statistically significant re.uction in all-cause.mortality in patie.ts administe.e. trane.amic acid(TXA)within 3 hours of *** the.publication of CRASH-2,significant ge.graphical variance.in the.use.of TXA for trauma patie.ts *** study aims to asse.s TXA use.for major trauma patie.ts with he.orrhagic shock in Ire.and afte. the.publication of ***:A re.rospe.tive.cohort study was conducte. using data de.ive. from the.Trauma Audit and Re.e.rch Ne.work(TARN).All injure. patie.ts in Ire.and be.we.n January 2013 and De.e.be. 2018 who had e.ide.ce.of he.orrhagic shock on pre.e.tation(as de.ine. by systolic blood pre.sure.SBP]e.e.e.igible.for *** at hospital discharge.was the.primary ***:During the.study pe.iod,a total of 234 patie.ts me. the.inclusion *** injure. patie.ts pre.e.ting with he.orrhagic shock,133(56.8%;95%confide.ce.inte.val[CI]50.2%–63.3%)re.e.ve. *** patie.ts that re.e.ve. TXA,a highe. proportion of patie.ts pre.e.te. with shock inde.>1(70.68%vs.57.43%)and highe. Injury Se.e.ity Score.ISS>25;49.62%vs.23.76%).Administration of TXA was not associate. with mortality at hospital discharge.odds ratio[OR]0.86,95%CI 0.31–2.38).CONCLUSIONS:Among injure. Irish patie.ts pre.e.ting with he.orrhagic shock,TXA was administe.e. to 56.8%of *** administe.e. with TXA we.e.on ave.age.more.se.e.e.y ***,a mortality be.e.it could not be.de.onstrate..

关键词： Trane.amic acid Shock Ire.and He.orrhage

Type.B monoamine.oxidase.inhibitors in ne.rological dise.se.:clinical applications base. on pre.linical findings

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Ne.ral Re.e.e.ation Re.e.rch 2024年第1期19卷 16-21页

作者： Marika Alborghe.ti e.oardo Bianchini Lanfranco De.Carolis Silvia Galli France.co e.Pontie.i Domiziana Rinaldi Ne.rology Unit NESMOS DepartmentFaculty of Medicine&PsychologySapienza-University of RomeSant’Andrea University HospitalRomeItaly De.artme.t of Clinical and Be.avioral Ne.rology IRCCS-Fondazione Santa LuciaRomeItaly

Type.B monoamine.oxidase.inhibitors,e.compassing se.e.iline.rasagiline.and safinamide.are.available.to tre.t Parkinson's *** drugs ame.iorate.motor symptoms and improve.motor fluctuation in the.advance. stage. of the.*** is also e.ide.ce.suppo rting the.be.e.it of type.B monoamine.oxidase.inhibitors on non-motor symptoms of Parkinson's dise.se.such as mood de.le.tion,cognitive.impairme.t,sleep disturbance.,and *** studie. indicate.that type.B monoamine.oxidase.inhibitors hold a strong ne.roprote.tive.pote.tial in Parkinson's dise.se.and othe. ne.rode.e.e.ative.dise.se. for re.ucing oxidative.stre.s and stimulating the.production and re.e.se.of ne.rotrophic factors,particularly glial ce.l line.de.ive. ne.rotrophic factor,which suppo rt dopamine.gic ***,safinamide.may inte.fe.e.with ne.rode.e.e.ative.me.hanisms,counte.a cting e.ce.sive.glutamate.ove.drive.in basal ganglia motor circuit and re.ucing de.th from *** to the.dual me.hanism of action,the.ne. ge.e.ation of type.B monoamine.oxidase.inhibitors,including safinamide.is gaining inte.e.t in othe. ne.rological pathologie.,and many supporting pre.linical studie. are.now *** pote.tial fie.ds of application conce.n e.ile.sy,Duche.ne.muscular dystrophy,multiple.scle.rosis,and above.all,ische.ic brain *** purpose.of this re.ie. is to inve.tigate.the.pre.linical and clinical pharmacology of se.e.iline.rasagiline.and safinamide.in Parkinson's dise.se.and be.ond,focusing on possible.future.the.ape.tic applications.

关键词： glial ce.l line.de.ive. ne.rotrophic factor(GDNF) glutamate ne.rological disorde.s ne.roprote.tion Parkinson's dise.se pre.linical studie. rasagiline safinamide se.e.iline type.B monoamine.oxidase.MAO_(B))inhibitors

Gut microbiota modulating inte.tinal ste. ce.l diffe.e.tiation

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World Journal of Ste. Ce.ls 2024年第6期16卷 619-622页

作者： Lin He.Che. Zhu Xiang-Fe.g Zhou Shu-e.Ze.g Le.Zhang Kuan Li De.artme.t of Alcohol and Drug De.e.de.ce.Tre.tme.t The Mental Hospital of Yunnan ProvinceKunming 650224Yunnan ProvinceChina De.artme.t of Physical e.ucation Kunming Medical UniversityKunming 650500Yunnan ProvinceChina De.artme.t of Ge.iatric Psychiatry The Mental Hospital of Yunnan ProvinceKunming 650224Yunnan ProvinceChina sleep Me.icine.Ce.te. The Mental Hospital of Yunnan ProvinceKunming 650224Yunnan ProvinceChina

Prolife.ation and diffe.e.tiation of inte.tinal ste. ce.l(ISC)to re.lace.damage. gut mucosal e.ithe.ial ce.ls in inflammatory state. is a critical ste. in ame.iorating gut ***,whe. this disorde.e. prolife.ation continue.,it induce. the.ISC to e.te. a cance.ous *** gut microbiota on the.fre. surface.of the.gut mucosal barrie. is able.to inte.act with ISC on a sustaine. ***-biota me.abolite. are.able.to re.ulate.the.prolife.ation of gut ste. and proge.itor ce.ls through transcription factors,while.in ste.dy state.diffe.e.tiate. colono-cyte. are.able.to bre.k down such me.abolite.,the.e.y prote.ting ste. ce.ls at the.gut *** the.future.the.gut flora and its me.abolite. me.iating the.re.ulation of ISC diffe.e.tiation will be.a pote.tial tre.tme.t for e.te.opathie..

关键词： Inte.tinal ste. ce.ls Gut microbiota Gut ste. niche Microe.vironme.t Probiotics

Asse.sing ve.tilation control strate.ie. in unde.ground parking garage.

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Building Simulation 2021年第3期14卷 701-720页

作者： Afshin Faramarzi Jongki Le. brent Ste.he.s Mohammad He.darine.ad De.artme.t of Civil Architecturaland Environmental EngineeringIllinois Institute of TechnologyChicagoILUSA

e.close. parking garage. re.uire.me.hanical ve.tilation fans to dilute.conce.trations of pollutants e.itte. from ve.icle.,which contribute. to e.e.gy use.and pe.k e.e.tricity *** study de.e.ops and applie. a simulation frame.ork combining multi-zone.airflow and contaminant transport mode.ing,fan affinity laws,and re.listic assumptions for ve.icle.traffic patte.ns and carbon monoxide.CO)e.issions to improve.our ability to pre.ict the.impacts of various ve.tilation control strate.ie. on indoor air quality and fan e.e.gy use.in parking *** simulation approach is validate. using me.sure. data from a parking garage.case.study and the. applie. to inve.tigate.fan e.e.gy use.pe.k powe. de.and,and re.ulting CO conce.trations for four diffe.e.t ve.tilation control strate.ie. in a mode. unde.ground parking garage.unde. a varie.y of assumptions for mode. *** four ve.tilation control strate.ie. e.aluate. include.one.simplistic sche.ule.i.e.,Always-On)and thre. de.and-base. strate.ie. in which fan spe.d is a function of CO conce.trations in the.space.,including Line.r-De.and Control Ve.tilation(DCV),Standardize. Variable.Flow(SVF),and a simple.On-Off *** e.timate. annual ave.age.fan e.e.gy consumption was consiste.tly lowe.t with the.Line.r-DCV strate.y,re.ulting in ave.age.±standard de.iation)e.e.gy savings across all mode.e. sce.arios of 84.3%±0.4%,72.8%±3.6%,and 97.9%±0.1%compare. to SVF,On-Off,and Always-On strate.ie.,*** utility of the.frame.ork de.cribe. he.e.n is that it can be.use. to mode. e.e.gy and indoor air quality impacts of othe. parking garage.configurations and control sce.arios.

关键词： carbon monoxide de.and control ve.tilation e.e.gy e.ficie.cy indoor air quality unde.ground parking garage