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拯救美元，拯救经济

海外经济评论 2008年第14期 22-24页

作者： Reuven brenner

【美国《华尔街日报》3月20日】现在很多人都在问这样一个问题：贝尔斯登公司（Bear Stearns Cos．）200亿美元的市值何以在一夜之间蒸发？但是几乎没有人注意到这样一个事实：自2002年以来，已有数万亿美元的公司市值和美国国债“蒸发... 详细信息

【美国《华尔街日报》3月20日】现在很多人都在问这样一个问题：贝尔斯登公司（Bear Stearns Cos．）200亿美元的市值何以在一夜之间蒸发？但是几乎没有人注意到这样一个事实：自2002年以来，已有数万亿美元的公司市值和美国国债“蒸发掉”了。问题的根源就在于美国联邦储备委员会（Fed）忽视了美元。

关键词：美元美国联邦储备委员会《华尔街日报》经济公司市值美国国债蒸发

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攻克现今测试仪器的硅壁垒

今日电子 2000年第11期 28-29页

作者： Marc brenner Tektronix公司

各公司相互利用对方的经验。

关键词：测试仪器硅锗化硅双极硅

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智能楼宇助力城市构建智能基础设施新生态

国内外机电一体化技术 2021年第2期24卷 19-20页

作者： Thomas brenner 西门子(中国)有限公司

新冠病毒疫情为城市管理和基础设施运营带来了前所未有的挑战。然而,大数据、人工智能、5G等技术在疫情中的不同应用也让我们看到了数字化和智能化技术赋予城市管理的巨大潜力,为更多城市数字化应用场景的发展带来机遇。在中国推进“新... 详细信息

新冠病毒疫情为城市管理和基础设施运营带来了前所未有的挑战。然而,大数据、人工智能、5G等技术在疫情中的不同应用也让我们看到了数字化和智能化技术赋予城市管理的巨大潜力,为更多城市数字化应用场景的发展带来机遇。在中国推进“新基建”的大背景下,人工智能、物联网等先进技术与基础设施的深度融合,将大力推进电网、楼宇、交通等领域的转型升级,从而打造更高效、更具韧性,更宜居的智慧城市。

关键词：转型升级基础设施人工智能城市数字化大数据智能楼宇物联网智能化技术

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源于***工作的现代经典物理学

力学进展 2000年第4期30卷 613-621页

作者： M.P. brenner H.A. Stone 李家春黄永念 Department of Mathematics Massachusetts Institute of Technology Cambridge Massachusetts Division of Engineering and Applied Sciences Harvard University Cambridge Massachusetts 中国科学院力学研究所北京大学力学与工程科学系

一位科学家的工作提供了一门完整课程的素材，涉及从流体动力学稳定性、湍流到流体电动力学、微生物的运动．

关键词：流体稳定性湍流统计理论爆炸波旋转流动位错

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月经和生育因素对妇女肺癌危险度的影响

中华流行病学杂志 2004年第7期25卷 590-593页

作者： AlinaV.brenner 王作元 RuthA.Klcinerman 王陇德 CatherineMetayer JayH.Lubin Radiation Epidemiology Branch Division of Cancer Epidemiology and GeneticsNational Cancer InstituteUSA 中国疾病预防控制中心辐射防护与核安全医学所中国卫生部

目的验证雌激素可能对肺癌危险度产生的影响方法 1994～1998年在甘肃省陇东地区进行了一项女性人群的病例对照研究,分析了月经和生育因素与肺癌危险度之间的关系。病例组为109例女性肺癌病例和435名女性为对照组,对照组是根据人口调... 详细信息

目的验证雌激素可能对肺癌危险度产生的影响方法 1994～1998年在甘肃省陇东地区进行了一项女性人群的病例对照研究,分析了月经和生育因素与肺癌危险度之间的关系。病例组为109例女性肺癌病例和435名女性为对照组,对照组是根据人口调查资料,按年龄和地区与病例频数匹配得到的。结果初潮年龄晚(趋势检验P=0.015)、绝经年龄晚(趋势检验P=0.074)的女性,其肺癌比值比较低。结论尽管有局限性,上述发现表明雌激素在女性肺癌病因学中起到一定作用。

关键词：月经因素生育因素妇女肺癌危险度病因学

Changing the paradigm：the potential for targeted therapy in laryngeal squamous cell carcinoma

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Cancer Biology & Medicine 2016年第1期13卷 87-100页

作者： Megan L.Ludwig Andrew C.Birkeland Rebecca Hoesli Paul Swiecicki Matthew E.Spector J.Chad brenner Department of Otolaryngology Head and Neck SurgeryUniversity of Michigan Medical SchoolAnn ArborMI 48109USA Cellular and Molecular Biology Program University of MichiqanAnn ArborMI 48109USA Department of Hematology Oncology University of Michigan Medical SchoolAnn ArborMI 48109USA Comprehensive Cancer Center University of Michigan Medical SchoolAnn ArborMI 48109USA

Laryngeal squamous cell carcinoma(LSCC) remains a highly morbid and fatal disease. Historically, it has been a model example for organ preservation and treatment stratification paradigms. Unfortunately, survival for LSCC has stagnated over the past few decades. As the era of next-generation sequencing and personalized treatment for cancer approaches, LSCC may be an ideal disease for consideration of further treatment stratification and personalization. Here, we will discuss the important history of LSCC as a model system for organ preservation, unique and potentially targetable genetic signatures of LSCC, and methods for bringing stratified, personalized treatment strategies to the 21^(st) century.

关键词： Head and neck cancer laryngeal squamous cell carcinoma genetics targeted therapy personalized medicine

Gastrointestinal Kaposi's sarcoma: Case report and review of the literature

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World Journal of Gastrointestinal Pharmacology and Therapeutics 2015年第3期6卷 89-95页

作者： Ann Joo Lee Lacie brenner Bashar Mourad Carmela Monteiro Kenneth J Vega Juan Carlos Munoz Division of Gastroenterology Department of Medicine University of Florida College of Medicine Jacksonville Department of Medicine University of Florida College of Medicine Jacksonville Department of Pathology University of Florida College of Medicine Jacksonville Division of Digestive Diseases and Nutrition University of Oklahoma Health Sciences Center

Kaposi's sarcoma(KS) of the gastrointestinal tract is not an uncommon disease among individuals with acquired immunodeficiency syndrome(AIDS). The majority is asymptomatic, and for this reason, gastrointestinal KS(GI-KS) remains undiagnosed. With continued tumor growth, considerable variation in clinical presentation occurs including abdominal pain, nausea, vomiting, iron deficiency anemia(either chronic or frank gastrointestinal bleeding), and rarely mechanical obstruction alone or combined with bowel perforation. Endoscopy with biopsy allows for histological and immunohistochemical testing to confirm the diagnosis of GI-KS among those with clinical symptoms. In previous studies, dual treatment with highly active antiretroviral therapy and systemic chemotherapy have been associated with improved morbidity and mortality in individuals with visceral KS. Therefore, investigators have suggested performing screening endoscopies in select patients for early detection and treatment to improve outcome. In this review, we describe a 44 years old man with AIDS and cutaneous KS who presented for evaluation of postprandial abdominal pain, vomiting, and weight loss. On upper endoscopy, an extensive, infiltrative,circumferential, reddish mass involving the entire body and antrum of the stomach was seen. Histologic examination later revealed spindle cell proliferation, and confirmatory immunohistochemical testing revealed human herpes virus 8 latent nuclear antigen expression consistent with a diagnosis of gastric KS. Following this, we present a comprehensive review of literature on KS with emphasis on gastrointestinal tract involvement and management.

关键词： Kaposi sarcoma Acquired immunodeficiency syndrome Gastrointestinal endoscopy Epidemiology Gastrointestinal tumor symptoms

Artificial intelligence using advanced imaging techniques and cholangiocarcinoma: Recent advances and future direction

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Artificial Intelligence in Gastroenterology 2022年第3期3卷 88-95页

作者： Aaron R brenner Passisd Laoveeravat Patrick J Carey Danielle Joiner Samuel H Mardini Manol Jovani Department of Internal Medicine University of Kentucky College of MedicineLexingtonKY 40536United States Division of Digestive Diseases and Nutrition University of Kentucky College of MedicineLexingtonKY 40536United States Division of Digestive Diseases and Nutrition University of Kentucky College of MedicineLexingtonKENTUCKY 40536United States Digestive Diseases and Nutrition University of Kentucky Albert B.Chandler HospitalLexingtonKY 40536United States

While cholangiocarcinoma represents only about 3%of all gastrointestinal tumors,it has a dismal survival rate,usually because it is diagnosed at a late *** utilization of Artificial Intelligence(AI)in medicine in general,and in gastroenterology has made gigantic ***,the application of AI for biliary disease,in particular for cholangiocarcinoma,has been *** use of AI in combination with clinical data,cross-sectional imaging(computed tomography,magnetic resonance imaging)and endoscopy(endoscopic ultrasound and cholangioscopy)has the potential to significantly improve early diagnosis and the choice of optimal therapeutic options,leading to a transformation in the prognosis of this feared *** this review we summarize the current knowledge on the use of AI for the diagnosis and management of cholangiocarcinoma and point to future directions in the field.

关键词： Cholangiocarcinoma Artificial intelligence Cholangioscopy Artificial neural network Machine learning Therapeutic endoscopy Endoscopic ultrasound

Longitudinal diffusion tensor magnetic resonance imaging analysis at the cohort level reveals disturbed cortical and callosal microstructure with spared corticospinal tract in the TDP-43^(G298S) ALS mouse model

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Translational Neurodegeneration 2019年第1期8卷 333-345页

作者： Hans-Peter Müller David brenner Francesco Roselli Diana Wiesner Alireza Abaei Martin Gorges Karin M.Danzer Albert C.Ludolph William Tsao Philip C.Wong Volker Rasche Jochen H.Weishaupt Jan Kassubek Department of Neurology University of UlmOberer Eselsberg 45RKUD-89081 UlmGermany German Center for Neurodegenerative Diseases(DZNE) UlmGermany Core Facility Small Animal MRI University of UlmUlmGermany Department of Pathology The Johns Hopkins University School of MedicineBaltimoreUSA

Background:In vivo diffusion tensor imaging(DTI)of the mouse brain was used to identify TDP-43 associated alterations in a mouse model for amyotrophic lateral sclerosis(ALS).Methods:Ten mice with TDP-43^(G298S) overexpression under control of the Thy1.2 promoter and 10 wild type(wt)underwent longitudinal DTI scans at 11.7 T,including one baseline and one follow-up scan with an interval of about *** brain-based spatial statistics(WBSS)of DTI-based parameter maps was used to identify longitudinal alterations of TDP-43^(G298S) mice compared to wt at the cohort *** were supplemented by tractwise fractional anisotropy statistics(TFAS)and histological evaluation of motor cortex for signs of neuronal ***:Alterations at the cohort level in TDP-43^(G298S) mice were observed cross-sectionally and longitudinally in motor areas M1/M2 and in transcallosal fibers but not in the corticospinal *** loss in layer V of motor cortex was detected in TDP-43^(G298S) at the later(but not at the earlier)timepoint compared to ***:DTI mapping of TDP-43^(G298S) mice demonstrated progression in motor areas M1/*** and TFAS are useful techniques to localize TDP-43^(G298S) associated alterations over time in this ALS mouse model,as a biological marker.

关键词： Diffusion tensor imaging Amyotrophic lateral sclerosis Mutant TDP-43 Fiber tracking Mouse brain