检索结果-南通市图书馆

Atmospheric Pollutants in a Commercial Region of Fortaleza, Ceará, Brazil: Integration of Health, Environment and Economy in Urban Planning to Improve Air Quality

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Geoscience and Environment Protection 2024年第5期12卷 92-112页

作者： Mônica Giovana Alves Cardoso Ratts brenna Kessy Silva Lima Gilvan Ribeiro dos Santos Fladimir de Lima Gondim Rinaldo Santos Araújo Mona Lisa Moura de Oliveira Francisco Sales Ávila Cavalcante Daniel Silveira Serra Science and Technology Center State University of Cear&#225 Cear&#225 Brazil Department of Chemistry and Environment Federal Institute of Cear&#225 Cear&#225 Brazil Center of Technological Sciences State University of Cear&#225 Cear&#225 Brazil

The accelerated growth of the vehicular fleet, the modernization of large urban centers, and the few adjustments to the road network in Fortaleza have intensified the problems of traffic and emissions of atmospheric pollutants, highlighting the necessity for strategic urban planning initiatives to address the escalating issues of traffic and pollution. With the objective of analyzing the indices of concentrations of atmospheric pollutants and estimating how these levels can affect human health, this work consists of a study of the analysis of air quality in the intense trade region of Fortaleza. For this, the analysis zone was divided into three perimeters (Major - Medium - Minor), where each perimeter was analyzed at 7 am, 12 noon and 5 pm. Concentrations of the type of O3, particulate matter (PM2.5 and PM10), CO2 and HCHO were collected. Our results demonstrate that most of the analyses are within the limits of current legislation;however, at certain times and perimeters, the analyses of CO2 and HCHO exceeded the established limits. In view of the above, we conclude that public policies to control air quality are necessary to reduce the damage to human health and the environment caused by pollutants.

关键词： Air Quality Urban Planning Particulate Material Health Impacts

Inducing prion protein shedding as a neuroprotective and regenerative approach in pathological conditions of the brain:from theory to facts

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第9期18卷 1869-1875页

作者： Andreu Matamoros-Angles Behnam Mohammadi Feizhi Song Mohsin Shafiq Santra brenna Berta Puig Markus Glatzel Hermann C.Altmeppen Institute of Neuropathology University Medical Center Hamburg-Eppendorf(UKE)HamburgGermany Department of Neurology Experimental Research in Stroke and Inflammation(ERSI)University Medical Center Hamburg-Eppendorf(UKE)HamburgGermany

In the last decades,the role of the prion protein(PrP) in neurodegenerative diseases has been intensively investigated,initially in prion diseases of humans(e.g., Creutzfeldt-J akob disease) and animals(e.g.,scrapie in sheep,chronic wasting disease in deer and elk,or "mad cow disease" in cattle).Templated misfolding of physiological cellular prion protein(PrPC) into an aggregation-prone isoform(termed PrP "Scrapie"(PrPSc)),self-re plication and spreading of the latter inside the brain and to peripheral tissues,and the associated formation of infectious proteopathic seeds(termed "prions")are among the essential pathogenic mechanisms underlying this group of fatal and transmissible spongiform *** r,key roles of the correctly folded PrPCwere identified in more common human brain diseases(such as Alzheimer s disease or Parkinson’s disease) associated with the misfolding and/or accumulation of other proteins(such as amyloid-β,tau or α-synuclein,respectively).PrPChas also been linked with n euro protective and regenerative functions,for instance in hypoxic/ischemic conditions such as ***,despite a mixed "bouquet" of suggested functions,our understanding of pathological and,especially,physiological roles played by PrPCin the brain and beyond is ce rtainly *** with various other proteins at the cell surfa ce or within intracellular compartments may account for the functional diversity linked with ***,conserved endogenous proteolytic processing of PrPCgenerates seve ral defined PrPCfragments,possibly holding intrinsic functions in physiological and pathological conditions,thus making the "true and complete biology" of this protein more complicated to be ***,we focus on one of those released PrPCfragments,namely shed PrP(sPrP),generated by a membrane-proximate ADAM10-mediated cleavage event at the cell surfa *** to other soluble PrP fragments(such as the N1 fragment representing PrP’s released N-ter

关键词： ADAM10 aggregation Alzheimer’s disease amyloid antibodies Creutzfeldt-Jakob disease enzymatic cleavage extracellular vesicles neurodegeneration neurotoxicity proteolytic processing stroke transmissible spongiform encephalopathies

Minimally invasive valve surgery:pushing boundaries over the eighty

在线全文

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2023年第4期20卷 276-283页

作者： Cristina Barbero Dario brenna Antonio Salsano Marco Pocar Erik Cura Stura Claudia Calia Viviana Sebastiano Mauro Rinaldi Davide Ricci Department of Cardiovascular and Thoracic Surgery Cittàdella Salute e della ScienzaUniversity of TurinTurinItaly Department of Integrated Surgical and Diagnostic Sciences University of GenoaGenoaItaly Department of Clinical Sciences and Community Health University of MilanMilanItaly

BACKGROUND Mean age of patients with valves diseases is significantly increasing,and,in the near future,cardiac surgeons will have to deal with a considerable number of patients aged more than 80 *** remarkable results gained by the minimally invasive approach have encouraged its application in more complex and fragile patients,such as older *** study aimed to identify the rate of early mortality and major complications,and independent predictors for mid-term mortality in octogenarians undergoing minimally invasive valve *** Octogenarian patients undergoing right mini-thoracotomy mitral and/or tricuspid valve surgery between 2006 and2020 were *** endpoint was to identify independent predictors for mid-term mortality,and secondary endpoints were operative morality,stroke,independent predictors for early composite outcome,and quality of life at *** Analysis was performed on 130 *** occurred in one patient(0.8%),while operative mortality was 6%(eight patients).One-year and five-year survival were 86% and 64%,*** regression identified age and creatinine level as independent predictors of mid-term mortality,survival analysis showed that age ≥ 84 years and creatinine level ≥ 1.22 mg/dL were the cut-off points for worst *** gender and hypertension were found to be independent predictors of early composite *** Results of the present study show that age alone should not be considered a contraindication for minimally invasive valve *** patients who are most likely to have survival and functional benefits after surgery is decisive to achieve optimal health outcomes and prevent futile procedures.

关键词： surgery valve gained

Omega-6支撑身体,Omega-3支撑大脑:均衡摄入对儿童大脑发育的影响

在线全文

学校读者我要写书评

暂无评论

粮油食品科技 2022年第3期30卷 7-15页

作者： J.Thomas brenna 德克萨斯大学奥斯汀分校戴尔医学院美国奥斯汀TX 78723 康奈尔大学伊萨卡美国纽约NY 14853

人体大脑和身体的发育,需要从食物中摄取均衡的营养物质。人类大脑是区分人类和其他动物的特征。食物中的必需脂肪酸是机体组织结构和功能的必要组成部分。Omega-6(O6)亚油酸(LA6)是皮肤组织的组成成分,且是炎症、血栓形成、免疫和其他... 详细信息

人体大脑和身体的发育,需要从食物中摄取均衡的营养物质。人类大脑是区分人类和其他动物的特征。食物中的必需脂肪酸是机体组织结构和功能的必要组成部分。Omega-6(O6)亚油酸(LA6)是皮肤组织的组成成分,且是炎症、血栓形成、免疫和其他信号分子的前体;Omega-3(O3)α-亚麻酸(ALA3),特别是其长链代谢产物——二十二碳六烯酸(DHA3),是大脑、视网膜和部分神经组织中的关键组分。从富含LA6脂肪酸(缺乏O3脂肪酸)的植物籽中提取出的廉价而优质油脂,是20世纪的西方国家食品工业生产的主要脂肪来源。在代谢通路中,高浓度的LA6脂肪酸可拮抗O3脂肪酸代谢,造成O3脂肪酸不足,因此,在给怀孕动物的饲料中,只提供富含LA6但缺乏O3脂肪酸的油脂作为唯一的脂肪来源,会导致幼崽大脑发育不良。过去20~30年的研究表明,低含量LA6且含DHA3的油脂可改善大脑的功能。近年来的研究较多集中在营养因素对大脑发育的影响,最新研究数据表明,脂肪酸平衡对营养不良儿童的大脑发育尤为重要。世界卫生组织(WHO)越来越重视大脑的营养健康,通过其下属的食品法典委员会,建议用于治疗严重急性营养不良儿童的即食治疗食品中,使用含有均衡脂肪酸组成/构成的脂肪。同样,脂肪酸均衡对老年人可能也很重要。目前,业界已经有了调整油脂成分的方法,以确保脂肪酸均衡,从而维持人体整个生命周期的大脑健康。

关键词：大脑发育二十二碳六烯酸 Omega-3脂肪酸 Omega-6脂肪酸高油酸油严重急性营养不良即食治疗性食品脂肪酸平衡

Safety and feasibility of same day discharge after per oral endoscopic pyloromyotomy in refractory gastroparesis: a pilot study

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2022年第12期135卷 1432-1437页

作者： Rushikesh Shah Huimin Chen Lucie F.Calderon Tonia Gooden Maryam Mubashir Shazia Rashid Syed Musa Raza Allison Derise Grace Mccurdy brenna Sanders Steve Keilin Qiang Cai Division of Digestive Diseases Emory University School of MedicineAtlantaGAUSA Division of Gastroenterology and Hepatology Shanghai nsitute of Digestive DiseaseRenj HospitalShanghai JjaoTong University School of MedicineShanghai 200127China Division of Gastroenterology and Hepatology Louisiana State UniversitShreveportLAUSA

Background:Gastroparesis is a debilitating medical condition with limited treatment *** per-oral pyloromyotomy(G-POEM)has emerged as a promising treatment option with remarkable short-term clinical success shown in multiple *** the post-procedure protocol is not standardized across many centers,the majority of the centers observes these patients in the hospital after the procedure for *** this single-center prospective study,we evaluated the safety and feasibility of same day discharge after the G-POEM ***:All the patients with refractory gastroparesis undergoing G-POEM from October 2019 to March 2020 were enrolled.A total of 25 patients were enrolled in the *** on the pre-defined criteria,patients were either discharged on the same day after the procedure or admitted to the hospital for further *** patient and procedure-related data were extracted from the chart *** analysis was performed(chi-squared test)on categorical variables after organizing categorical variables as numeric counts or *** student t test was performed on continuous variables after reporting as mean and standard *** analysis with a smaller sample size,Fisher exact and Mann–Whitney tests were ***:A total of 25 patients were *** technical success of G-POEM was 100%and clinical success was 80%(20/25)at 1-month *** the 25 patients,9 patients(36%)were discharged on the same day according to the procedure from the recovery *** the remaining 16 patients who were admitted to the hospital post-procedure,10(40%)were admitted due to procedure-related causes while other admissions were either pre-planned or due to social *** average Charlson comorbidity index was lower in the same day discharge group(P<0.05).The number of patients requiring double myotomy was higher in the same day discharge group(P<0.05).The overall complication rate of G-POEM in the study cohort w

关键词： G-POEM Pyloromyotomy Gastroparesis Gastric per-oral pyloromyotomy

Metabolic and physiological regulation of Chlorella sp.(Trebouxiophyceae, Chlorophyta) under nitrogen deprivation

在线全文

学校读者我要写书评

暂无评论

Journal of Oceanology and Limnology 2019年第1期37卷 186-198页

作者： YONG Wai-Kuan LIM Phaik-Eem VELLO Vejeysri SIM Kae-Shin ABDUL MAJID Nazia MUSTAFA Emienour Muzalina NIK SULAIMAN Nik Meriam LIEW Kan-Ern CHEN brenna Jia-Tian PHANG Siew-Moi Institute of Ocean and Earth Sciences University of Malaya Institute of Graduate Studies University of Malaya Institute of Biological Sciences Faculty of Science University of Malaya School of Fisheries and Aquaculture Sciences University of Malaysia Department of Chemical Engineering Faculty of Engineering University of Malaya Airbus Group Malaysia Menara HLA Aerospace Malaysia Innovation Centre

A freshwater green microalgae Chlorella sp., UMACC344 was shown to produce high lipid content and has the potential to be used as feedstock for biofuel production. In this study, photosynthetic effciency, biochemical pro?les and non-targeted metabolic pro?ling were studied to compare between the nitrogen-replete and deplete conditions. Slowed growth, change in photosynthetic pigments and lowered photosynthetic effciency were observed in response to nitrogen deprivation. Biochemical pro?les of the cultures showed an increased level of carbohydrate, lipids and total fatty acids, while the total soluble protein content was lowered. A trend of fatty acid saturation was observed in the nitrogen-deplete culture with an increase in the level of saturated fatty acids especially C16:0 and C18:0, accompanied by a decrease in proportions of monounsaturated and polyunsaturated fatty acids. Fifty-nine metabolites, including amino acids, lipids, phytochemical compounds, vitamins and cofactors were signi?cantly dysregulated and annotated in this study. Pathway mapping analysis revealed a rewiring of metabolic pathways in the cells, particularly purine, carotenoid, nicotinate and nicotinamide, and amino acid metabolisms. Within the treatment period of nitrogen deprivation, the key processes involved were reshu ? ing of nitrogen from proteins and photosynthetic machinery, together with carbon repartitioning in carbohydrates and lipids.

关键词： metabolic profiling Chlorella sp. nitrogen stress lipid fatty acid

Voltage Control in Smart Grids: An Approach Based on Sensitivity Theory

在线全文

学校读者我要写书评

暂无评论

Journal of Electromagnetic Analysis and Applications 2010年第8期2卷 467-474页

作者： Morris brenna Ettore De Berardinis Federica Foiadelli Gianluca Sapienza Dario Zaninelli 不详

Due to the development of Distributed Generation (DG), which is installed in Medium-Voltage Distribution Networks (MVDNs) such as generators based on renewable energy (e.g., wind energy or solar energy), voltage control is currently a very important issue. The voltage is now regulated at the MV busbars acting on the On-Load Tap Changer of the HV/MV transformer. This method does not guarantee the correct voltage value in the network nodes when the distributed generators deliver their power. In this paper an approach based on Sensitivity Theory is shown, in order to control the node voltages regulating the reactive power exchanged between the network and the dispersed generators. The automatic distributed voltage regulation is a particular topic of the Smart Grids.

关键词： Voltage Regulation Reactive Power Injection Distributed Generation Smart Grids Sensitivity Theory Renewable Energy

Current Distortion Evaluation in Traction 4Q Constant Switching Frequency Converters

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Electromagnetic Analysis and Applications 2009年第3期1卷 129-137页

作者： M. brenna F. FOIADELLI M. ROSCIA D. ZANINELLI 不详

The paper deals with the power quality analysis of interlaced four quadrant (4Q) converters with constant switching frequency. These are in fact the input stages of the locomotives and high speed trains supplied by 25 kV, 50 Hz and 15 kV, 16.7 Hz lines. Due to the high power needed for the trains circulation, the 4Q converter can absorb distorted currents, whose harmonic content can affect the signaling systems and communication devices. The presence of more converters gives the opportunity, using dedicated commutation strategy, to interlace them in order to reduce the harmonic content in the absorbed current. In the paper a suitable model of more 4Q converters is developed. The control logic implemented in the model allows the evaluation of the harmonic contribution of both single converter and the interlaced configuration. The analysis is carried out through electromagnetic transient simulations.

关键词： Four Quadrant (4Q) Converter Interlacing Traction Systems Power Quality Analysis Commutation Strategy

Atlas of Endoscopic Ultrasonography 1

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论