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Genes & Diseases 2015年第1期2卷 46-56页

作者： Hua Zhao Elena Gonzalezgugel Lei Cheng brendon richbourgh Lin Nie Chuanju Liu Department of Orthopaedic Surgery New York University School of MedicineNew YorkNY 10003United States Department of Spine Surgery Qilu Hospital of Shandong UniversityJinan250014China Department of Cell Biology New York University School of MedicineNew YorkNY 10016United States

p204 is a member of the interferon-inducible p200 family proteins in *** p200 family has been reported to be multifunctional regulators of cell proliferation,differentiation,apoptosis and ***-inducible protein 16(IFI16)is regarded as the human ortholog of p204 in several *** is possibly due to the similarity of their *** the consistency of their functions is still ***,an emerging focus has been placed upon the role of the p200 proteins as sensors for microbial DNA in innate immune responses and provides new insights into infections as well as autoimmune *** review specially focuses on IFI16 and p204,the member of p200 family in human and murine respectively,and their pathophysiological roles in innate immune responses,cell differentiation and proliferation.

关键词： DNA sensor IFI16 Innate immune response Multifunctional regulator p204

The Effect of Reaction Temperature, Catalyst Concentration and Alcohol Ratio in the Production of Biodiesel from Raw and Purified Castor Oil

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Advances in Chemical Engineering and Science 2024年第3期14卷 137-154页

作者： Sandile brendon Masango Peterson Thokozani Ngema Olusegun Ayodeji Olagunju Suresh Ramsuroop Department of Chemical Engineering Durban University of Technology Green Engineering Group-Chemical Thermodynamics Steve Biko Campus Durban South Africa Department of Chemical Engineering Cape Peninsula University of Technology Cape Town South Africa

In this study, a homogeneous alkaline catalyst was used in the production of biodiesel from raw and refined castor oil feedstock. The effect of potassium hydroxide (KOH) as a catalyst between the two feedstocks, raw and refined castor oil was compared. The transesterification technique was utilized in this study, aiming to investigate the effect of different parameters, which include the reaction temperature, methanol-to-oil mole ratio, and catalyst concentration at a constant period of 90 minutes. The result revealed the performance of the KOH catalyst on raw castor oil yielded 98.49% FAME, which was higher than the refined castor oil which yielded 97.9% FAME. The optimal conditions obtained from refined castor oil were applied to raw castor oil because of the same properties. The fuel quality of castor oil and produced biodiesel were tested for physicochemical properties.

关键词： Biodiesel Fuel Raw Castor Oil Refined Castor Oil Transesterification Process

Geodiversity in the Yellow River source zone

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Journal of Geographical Sciences 2013年第5期23卷 775-792页

作者： brendon BLUE Gary BRIERLEY YU Guo-an School of Environment University of Auckland Private Bag 92019 Auckland New Zealand Key Laboratory of Water Cycle and Related Land Surface Processes Institute of Geographic Sciences and Natural Resources Research CAS Beijing 100101 China

It is a key premise of ＇ecosystem approaches＇ to natural resources management that we must have an appropriate understanding of biodiversity values, and controls upon them, if we wish to manage them effectively. These biodiversity values, and associated ecosystem functionality, vary with space and time and are tied directly to landscape-scale relationships and evolutionary traits. In riverine systems, nested hierarchical principles provide a useful platform to assess relationships between landscape components across a range of scales. These understandings are most instructively synthesized through catchment-scale analyses. This paper outlines a rationale for systematic catchment-wide appraisals of river geodiversity. An initial application of these principles is presented for the Yellow River source zone in Qinghai Province, western China. Geo-ecological relationships are outlined for five broad sections of the trunk stream, highlighting implications for the management of these individual landscape compartments and for the system as a whole.

关键词： geodiversity river classification anabranching Qinghai-Tibet Plateau Sanjiangynan Yellow River source zone

Risk of bias and reporting practices in studies comparing VO2max responses to sprint interval *** training:A systematic review and meta-analysis

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Journal of Sport and Health Science 2022年第5期11卷 552-566页

作者： Jacob T.Bonafiglia Hashim Islam Nicholas Preobrazenski brendon J.Gurd School of Kinesiology and Health Studies Queen’s UniversityKingstonOntarioK7L 3N6Canada

Background:It remains unclear whether studies comparing _(max)imal oxygen uptake(VO_(2max))response to sprint interval training(SIT)***-intensity continuous training(MICT)are associated with a high risk of bias and poor reporting *** purpose of this study was to evaluate the risk of bias and quality of reporting in studies comparing changes in VO_(2max) between SIT and ***:We conducted a comprehensive literature search of 4 major databases:AMED,CINAHL,EMBASE,and *** were excluded if participants were not healthy adult humans or if training protocols were unsupervised,lasted less than 2 weeks,or utilized mixed exercise *** used the Cochrane Collaboration tool and the CONSORT checklist for non-pharmacological trials to evaluate the risk of bias and reporting quality,***:Twenty-eight studies with 30 comparisons(3 studies included 2 SIT groups)were included in our meta-analysis(n=360 SIT participants:body mass index(BMI)=25.9±3.7 kg/m^(2),baseline VO_(2max)=37.9±8.0 mL/kg/min;n=359 MICT participants:BMI=25.5±3.8 kg/m^(2),baseline VO_(2max)=38.3±8.0 mL/kg/min;all mean±SD).All studies had an unclear risk of bias and poor reporting ***:Although we observed a lack of superiority between SIT and MICT for improving VO_(2max)(weighted Hedge’s g=0.004,95%con-fidence interval(95%CI):-0.08 to 0.07),the overall unclear risk of bias calls the validity of this conclusion into *** studies using robust study designs are needed to interrogate the possibility that SIT and MICT result in similar changes in VO_(2max).

关键词： Bias Cardiorespiratory fitness CONSORT Moderate-intensity continuous training Sprint interval training

Analysis of controls upon channel planform at the First Great Bend of the Upper Yellow River, Qinghai-Tibet Plateau

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Journal of Geographical Sciences 2013年第5期23卷 833-848页

作者： LI Zhiwei WANG Zhaoyin PAN Baozhu DU Jun Gary BRIERLEY YU Guo-an brendon BLUE State Key Laboratory of Hydroscience and Engineering Tsinghua University Beijing 100084 China Changjiang River Scientific Research Institute Wuhan 430010 China School of Environment University of Auckland Private Bag 92019 Auckland New Zealand Key Laboratory of Water Cycle and Related Land Surface Processes Institute of Geographic Sciences and Natural Resources Research CAS Beijing 100101 China

The 270 km long section of the Upper Yellow River at the First Great Bend is comprised of single channel and multiple channel systems that alternate among anastomosing, anabranching, meandering and braided reaches. The sequence of downstream pattern changes is characterized as： anastomosing-anabranching, anabranching-meandering, meandering-braided and braided-meandering. Remote sensing images, DEM data and field investigations are used to assess ahd interpret controls on these reach transitions. Channel slope and bed sediment size are key determinants of transitions in channel planform. Anas- tomosing reaches have a relatively high bed slope （0.86‰） and coarser sediment bed material （d50 = 3.5 mm）. In contrast, meandering reaches have a low slope （0.30‰） and fine sediment bed material （d50 = 0.036 mm）. The transition from a meandering to braided pattern is characterized by an increase in channel width-depth ratio, indicating the important role of bank strength （i.e. cohesive versus non-cohesive versus channel boundaries）. Interestingly, the braided-meandering and meandering-braided transitions are coincident with variable flow inputs from tributary rivers （Baihe and Heihe rivers respectively）. Theoretical analysis of the meandering-braided transition highlights the key control of channel width-depth ratio as a determinant of channel planform.

关键词： Yellow River Source river pattern diversity river pattern transition anastomosing river ana- branching river meandering river braided river

Fluvial diversity in relation to valley setting in the source region of the Yangtze and Yellow Rivers

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Journal of Geographical Sciences 2013年第5期23卷 817-832页

作者： YU Guo-an LIU Le LI Zhiwei LI Yanfu HUANG Heqing Gary BRIERLEY brendon BLUE WANG Zhaoyin PAN Baozhu Key Laboratory of Water Cycle and Related Land Surface Processes Institute of Geographic Sciences and Natural Resources Research CAS Beijing 100101 China State Key Laboratory of Hydroscience and Engineering Tsinghua University Beijing 100084 China School of Environment University of Auckland Private Bag 92019 Auckland New Zealand Changjiang River Scientific Research Institute Wuhan 430010 China

The spatial distribution of valley setting （laterally-unconfined, partly-confined, or confined） and fluvial morphology in the source region of the Yangtze and Yellow Rivers is contrasted and analyzed. The source region of the Yangtze River is divided into 3 broad sections （I, II and III） based on valley setting and channel gradient, with the upstream and downstream sections being characterized by confined （some reaches partly-confined） valleys while the middle section is characterized with wide and shallow, laterally-unconfined valleys. Gorges are prominent in sections I and III, while braided channel patterns dominate section II. By contrast, the source region of the Yellow River is divided into 5 broad sections （sections I-V） based on valley characteristics and channel gradient. Sections I, II and IV are alluvial reaches with mainly laterally-unconfined （some short reaches partly-confined） valleys. Sections III and V are mainly confined or partly-confined. Greater morphological diversity is evident in the source region of the Yellow River relative to the upper Yangtze River. This includes braided, anabranching, anastomosing, meandering and straight alluvial patterns, with gorges in confined reaches. The macro-relief （elevation, gradient, aspect, valley alignment and confinement） of the region, linked directly to tectonic movement of the Qinghai-Tibet Plateau, tied to climatic, hydrologic and biotic considerations, are primary controls upon the patterns of river diversity in the region.

关键词： valley setting fluvial morphology river patterns spatial distribution source region of the Yangtze and Yellow Rivers

Bed load transport under different streambed conditions-a field experimental study in a mountain stream

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International Journal of Sediment Research 2012年第4期27卷 426-438页

作者： Guo-an YU Zhao-yin WANG He Qing HUANG Huai-xiang LIU brendon BLUE Kang ZHANG Key Laboratory of Water Cycle and Related Land Surface Processes Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of Sciences State Key Laboratory of Hydroscience and Engineering Tsinghua University Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Nanjing Hydraulic Research Institute School of Environment The University of Auckland Pearl River Hydraulic Research Institute

Bed load transport in mountain streams is closely linked to streambed *** structures are arrangements of boulders and cobbles deposited during extreme floods,in a stable configuration exhibiting high dissipation of *** experiments were carried out in a mountain stream in Yunnan,southwestern China,studying bed load movement on three typical streambeds,i.e.,with well developed,partially developed,and no *** underwater observation and video-capturing system was designed to observe and measure the movement of bed load *** initiation mode, trajectory,velocity,and acceleration of bed load particles under the three conditions were observed and *** showed that the bed load movement was highly associated with streambed *** well-developed structures,bed load particles moved intermittently through saltation and the bed load transport rate was very *** partially-developed structures most bed load particles moved through saltation but a portion of sediment moved in sliding and *** the case with no streambed structure(plane bed) contact load motion(sliding and rolling) gradually became ***,laminated load motion occurred and became the main component of bed load transport when the flow discharge and incoming sediment load were very *** load motion was a special form of bed load motion with an extremely high *** load transport and streambed structure both acted to dissipate flow energy and were mutually *** rates of bed load transport occurred in the streams with no or poor bed structures,and low bed load transport was associated with well developed *** bed load transport rate was inversely correlated to the degree of streambed development.

关键词： Bed load transport Streambed structure Mountain stream Underwater observation and Video capturing system

Comorbid bipolar disorder and obsessive-compulsive disorder: state of the art in pediatric patients

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上海精神医学 2015年第6期27卷 386-387页

作者： Matteo TONNA Andrea AMERIO Anna ODONE brendon STUBBS S.Nassir GHAEMI Department of Mental Health Local Health Service Department of Clinical and Experimental Medicine University of Parma Mood Disorders Program Tufts Medical Center Department of Biomedical Biotechnological and Translational Sciences Unit of Public Health University of Parma Institute of Psychiatry Kings College London Tufts University Medical School Department of Psychiatry and Pharmacology

To the editor:Apparent comorbidity between bipolar disorder（BD）and anxiety disorders is a common condition in psychiatry,[1,2]one of the most difficult to manage being the co-occurrence of BD and obsessive-compulsive disorder（OCD）.[3,4]In 1860 French psychiatrist BénédictAugustin Morel first described patients with symptoms typical of what is now considered comorbid BD and OCD.[5]A century later,when categorizing

关键词：病患护理术后观察医疗方法

Phase segregation in inorganic mixed-halide perovskites:from phenomena to mechanisms

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Photonics Research 2020年第11期8卷 I0001-I0016页

作者： Yutao Wang Xavier Quintana Jiyun Kim Xinwei Guan Long Hu Chun-Ho Lin brendon Tyler Jones Weijian Chen Xiaoming Wen Hanwei Gao Tom Wu School of Materials Science and Engineering and Advanced Materials and Manufacturing Futures Institute University of New South Wales(UNSW)SydneyNSW 2052Australia Department of Physics Florida State UniversityTallahasseeFlorida 32306USA Centre for Translational Atomaterials Swinburne University of TechnologyHawthornVIC 3122Australia

Halide perovskites,such as methylammonium lead halide perovskites(MAPbX3,X=I,Br,and Cl),are emerging as promising candidates for a wide range of optoelectronic applications,including solar cells,light-emitting diodes,and photodetectors,due to their superior optoelectronic ***-inorganic lead halide perovskites CsPbX3 are attracting a lot of attention because replacing the organic cations with Cs+enhances the stability,and its halide-mixing derivatives offer broad bandgap tunability covering nearly the entire visible ***,there is evidence suggesting that the optical properties of mixed-halide perovskites are influenced by phase segregation under external stimuli,especially illumination,which may negatively impact the performance of optoelectronic *** is reported that the mixed-halide perovskites in forms of thin films and nanocrystals are segregated into a low-bandgap I-rich phase and a high-bandgap Br-rich ***,we present a critical review on the synthesis and basic properties of all-inorganic perovskites,phase-segregation phenomena,plausible mechanisms,and methods to mitigate phase segregation,providing insights on advancing mixed-halide perovskite optoelectronics with reliable performance.

关键词： properties. spectrum. perovskite

The Effect of Reaction Temperature, Catalyst Concentration and Alcohol Ratio in the Production of Biodiesel from Raw and Purified Castor Oil

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