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Risk of bias and reporting practices in studies comparing VO2max responses to sprint interval vs.continuous training:A systematic review and meta-analysis

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journal of Sport and Health Science 2022年第5期11卷 552-566页

作者： jacob T.Bonafiglia Hashim Islam Nicholas Preobrazenski brendon j.gurd School of Kinesiology and Health Studies Queen’s UniversityKingstonOntarioK7L 3N6Canada

Background:It remains unclear whether studies comparing _(max)imal oxygen uptake(VO_(2max))response to sprint interval training(SIT)vs.moderate-intensity continuous training(MICT)are associated with a high risk of bias and poor reporting quality.The purpose of this study was to evaluate the risk of bias and quality of reporting in studies comparing changes in VO_(2max) between SIT and MICT.Methods:We conducted a comprehensive literature search of 4 major databases:AMED,CINAHL,EMBASE,and MEDLINE.Studies were excluded if participants were not healthy adult humans or if training protocols were unsupervised,lasted less than 2 weeks,or utilized mixed exercise modalities.We used the Cochrane Collaboration tool and the CONSORT checklist for non-pharmacological trials to evaluate the risk of bias and reporting quality,respectively.Results:Twenty-eight studies with 30 comparisons(3 studies included 2 SIT groups)were included in our meta-analysis(n=360 SIT participants:body mass index(BMI)=25.9±3.7 kg/m^(2),baseline VO_(2max)=37.9±8.0 mL/kg/min;n=359 MICT participants:BMI=25.5±3.8 kg/m^(2),baseline VO_(2max)=38.3±8.0 mL/kg/min;all mean±SD).All studies had an unclear risk of bias and poor reporting quality.Conclusion:Although we observed a lack of superiority between SIT and MICT for improving VO_(2max)(weighted Hedge’s g=0.004,95%con-fidence interval(95%CI):-0.08 to 0.07),the overall unclear risk of bias calls the validity of this conclusion into question.Future studies using robust study designs are needed to interrogate the possibility that SIT and MICT result in similar changes in VO_(2max).

关键词： Bias Cardiorespiratory fitness CONSORT Moderate-intensity continuous training Sprint interval training

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Extremely low-volume, high-intensity interval training improves exercise capacity and increases mitochondrial protein content in human skeletal muscle

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Open journal of Molecular and Integrative Physiology 2013年第4期3卷 202-210页

作者： jasmin K. Ma Trisha D. Scribbans Brittany A. Edgett j. Colin Boyd Craig A. Simpson jonathan P. Little brendon j. gurd Department of Emergency Medicine Kingston General Hospital Kingston Canada Department of Health and Social Development University of British Columbia Okanagan Kelowna Canada Department of Kinesiology Queen’s University Kingston Canada

Purpose: The purpose of the present study was to evaluate whole-muscle content of several proteins involved in the regulation of skeletal muscle mitochondrial protein content and anaerobic capacity following 4 weeks of extremely low-volume high-intensity interval training (HIT). Methods: Young, healthy, recreationally active adult males (n = 8) trained 4 times a week for 4 weeks on a cycle ergometer. Each session involved 4 min of total exercise comprised of eight 20 s intervals at ~170% of peak aerobic power separated by 10 s rest. Muscle biopsies were taken prior to (pre) and ~72 hrs post-training (post). Par- ticipants completed an incremental peak oxygen up- take (VO2peak) test and a Wingate test pre-, mid-, and post-training. Results: VO2peak was elevated (p p < 0.05) and post-training (pre: 40.5 ± 3.8 ml·kg-1·min-1, mid: 43.4 ± 2.5 ml·kg-1·min-1, post-: 47.2 ± 2.9 ml·kg-1·min-1). Wingate mean power also increased with training (pre-: 701.0 ± 73.0 W, mid-: 745.5 ± 73.3 W, post-: 786.8 ± 80.0 W). While maximal citrate synthase activity was unchanged, protein expression of the mitochondrial protein cytochrome c oxidase (COX) subunit I (+27%;p p p = 0.08) increased. Increases (p α (+19%), and nuclear PGC-1α (+46%) were also observed after 4 weeks of HIT. No changes were observed in the whole-muscle contents of PDHe1a, PDK4, SIRT1, mTOR, S6K1, MCT1, or PFK protein. Conclusions: These results demonstrate that several mitochondrial protein (but not citrate synthase activity), PGC-1α protein content, and exercise capacity can be improved in only 4 min of total training time per day, 4 days per wk using HIT cycle training.

关键词： PGC-1α Mitochondrial Biogenesis High-Intensity Interval Training SIRT1 Aerobic Fitness

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一生情,一世缘——舒曼与克拉拉的爱情故事

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新东方英语（中英文版） 2011年第2期 50-54页

作者： j. A. brendon 辛献云

他是一位感情丰沛的作曲家，谱写了无数传世之作；她是一位天资聪颖的钢琴家，演奏技艺炉火纯情。他们两人的相遇将擦出怎样的火花？

关键词：爱情故事克拉拉舒曼演奏技艺作曲家钢琴家

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