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Mitotic crossover- an evolutionary rudiment which promotes carcinogenesis of colorectal carcinoma

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World Journal of Gastroenterology 2014年第35期20卷 12522-12525页

作者： branislav Rovcanin Ivan Ivanovski Olivera Djuric Dimitrije Nikolic Jelena Petrovic Petar Ivanovski Institute for Human Genetics Faculty of MedicineUniversity of Belgrade Institute for Mother and Child Health Care Faculty of MedicineUniversity of Belgrade Institute for Epidemiology Faculty of MedicineUniversity of Belgrade University Children’s Hospital Faculty of MedicineUniversity of Belgrade Faculty of Medicine University of Belgrade

Mitotic crossover is a natural mechanism that is a main source of the genetic variability of primitive *** complex organisms such as mammals,it represents an evolutionary rudiment which persisted as one of the numerous DNA repair mechanisms,and results in the production of homozygous allele combinations in all heterozygous genes located on the chromosome arm distal to the *** event is familiar as loss of heterozygosity,which is one of the key mechanisms responsible for the development and progression of almost all *** propose the hypothesis in which mitotic crossover is a principal source of the increased loss of heterozygosity that leads to the initiation and progression of colorectal *** hypothesis could be tested by in vitro inhibition of Rad51 protein,orthotopic grafting of human colon cancer tissue into the gut of mice,and treatment with potential *** these procedures,the frequency of mitotic crossover would be *** development of selective inhibitors of mitotic crossover could stop further carcinogenesis of colorectal carcinoma,as well as many other neoplastic *** of heterozygosity is an event responsible for carcinogenesis,its reduction by selective inhibitors of mitotic crossover could have a positive effect on cancer chemoprevention,as well as on growth reduction and a cessation in the progression of earlier developed tumors.

关键词： Mitotic crossing over Loss of heterozygosity Carcinogenesis Inhibitors Colorectal carcinoma Cancer chemoprevention

Matlab-Simulink Simulation Model of Electric Multiple Unit(EMU)Series ŽS 413/417 in Traction and Electric Braking Mode

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Journal of Energy and Power Engineering 2024年第1期18卷 18-28页

作者： branislav Gavrilovic Academy of Technical and Art Applied Studies Belgrade Railway College BelgradeSerbia

In the paper,the Matlab-Simulink model of simulation of operation of theŽS 413/417 series EMU(electric multiple unit)in traction and braking mode is exposed where changes are observed:stator currents of three-phase traction motors,traction electric motor speeds and EMU,electromagnetic torque on the rotor shaft of the traction electric motor and DC(direct current)bus *** model allowed review of the listed parameters for:different allowed values of contact network voltage and total voltage distortion at the place of connection of the EMU to the contact network,different mechanical loads of EMU and traction electric motor and different train speeds and rotation of traction electric *** conclusions were made through the analysis of the simulation results obtained.

关键词： Simulations EMU Serbian railways

Investigation of chlorinated phenols sorption mechanisms on different layers of the Danube alluvial sediment

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Journal of Environmental Sciences 2020年第12期32卷 134-142页

作者： Tamara Apostolovic Jelena Trickovic Marijana Kragulj Isakovski branislav Jovic Snežana Maletic Aleksandra Tubic Jasmina Agbaba University of Novi Sad Faculty of SciencesDepartment of ChemistryBiochemistry and Environmental ProtectionTrg Dositeja Obradovica 3Novi SadSerbia

The characteristics of the Danube river alluvial sediment are of great importance in assessing the risk for transport of pollutants to drinking water sources. Characterization of the sediment column layers has shown that the alluvial sediment, sampled near the city of Novi Sad, is a mesoporous sandy material with certain differences in the properties of individual layers. In order to investigate the sorption mechanisms of four chlorinated phenols(CPs) on the alluvial deposit, static sorption experiments were performed at pH 4, 7 and 10. The results of sorption experiments, confirmed by principal components analysis sugest different mechanisms govern the sorption process at different p H conditions. This can be attributed to the molecular characteristics of CPs, geosorbent properties and to variations in the surface charge of the sorbent at different p H conditions.

关键词： Sorption mechanisms Chlorinated phenols Alluvial sediment Principal component analysis

Whither the United Nations at the Start of the 21st Century:An Institution for Changing or Extending the Old Global Order

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国际经济法学刊 2008年第2期 15-32页

作者： branislav Gosovic 不详

Professor An Chen has asked me to address the topic of'The strong and the weak in the UN:the South’s collective struggle to change the world order'.Following his wish,I have framed my presentation around the issue of North-South relations and the continuing divisions that separate developed and developing countries in the United Nations.I will be looking

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Cardiac autonomic dysfunction in patients with gastroesophageal reflux disease

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World Journal of Gastroenterology 2015年第22期21卷 6982-6989页

作者： branislav Milovanovic Branka Filipovic Slavica Mutavdzin Marija Zdravkovic Tatjana Gligorijevic Jovana Paunovic Marina Arsic Department of Cardiology Neurocardiology Laboratory Clinical and Hospital Center "Bezanijska Kosa" Department of Gastroenterology Clinical and Hospital Center "Bezanijska Kosa" Department of Cardiology Clinical and Hospital Center "Bezanijska Kosa"

AIM: To investigate autonomic nervous function in patients with a diagnosis of gastroesophageal reflux disease(GERD).METHODS: The investigation was performed on 29patients(14 men), aged 18-80 years(51.14 ± 18.34),who were referred to our Neurocardiology Laboratory at the Clinical and Hospital Center "Bezanijska Kosa"with a diagnosis of GERD. One hundred sixteen healthy volunteers matched in age and sex with the examinees served as the control group. The study protocol included the evaluation of autonomic function and hemodynamic status, short-term heart rate variability(HRV) analysis, 24 h ambulatory ECG monitoring with long-term HRV analysis and 24 h ambulatory blood pressure ***: Pathologic results of cardiovascular reflex test were more common among patients with reflux compared to the control group. Severe autonomic dysfunction was detected in 44.4% of patients and in7.9% of controls(P < 0.001). Parameters of short-term analysis of RR variability, which are the indicators ofvagal activity, had lower values in patients with GERD than in the control group. Long-term HRV analysis of time-domain parameters indicated lower values in patients with reflux disease when compared to the control group. Power spectral analysis of long-term HRV revealed lower low- and high-frequency *** 24 h ambulatory blood pressure analysis showed significantly higher values of systolic blood pressure and pulse pressure in the reflux group than in the control ***: Patients with GERD have distortion of sympathetic and parasympathetic components of the autonomic nervous system, but impaired parasympathetic function appears more congruent to GERD.

关键词： Autonomic nervous system Blood pressuremonitoring Cardiovascular reflex test ECG monitoring Gastroesophageal reflux disease

Dark Matter and Dark Energy from Lattice Model of Universe

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Journal of High Energy Physics, Gravitation and Cosmology 2024年第3期10卷 1045-1053页

作者： branislav Majerník Faculty of Mathematics Physics and Informatics Comenius University Bratislava Slovakia

The article considers a conceptual universe model as a periodic lattice (network) with nodes defined by the wave function in a background-independent Hamiltonian based on their relations and interactions. This model gives rise to energy bands, similar to those in semiconductor solid-state models. In this context, valence band holes are described as dark matter particles with a heavy effective mass. The conducting band, with a spontaneously symmetry-breaking energy profile, contains particles with several times lighter effective mass, which can represent luminous matter. Some possible analogies with solid-state physics, such as the comparison between dark and luminous matter, are discussed. Additionally, tiny dark energy, as intrinsic lattice Casimir energy, is calculated for a lattice with a large number of lattice nodes.

关键词： Dark Energy Dark Matter Lattice Universe Model

Marketing in the Function of Promotion of Tourism and Hunting Tourism Potentials in Rural Regions

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Journal of Environmental Science and Engineering(B) 2012年第6期1卷 741-747页

作者： branislav Zivkovic The Faculty of Management in Zajecar Megatrend University Zajecar 19000 Serbia

This paper presents the importance of the development of Serbian rural regions, and analyzes their marketing management potentials. Thus the paper aims to examine rural tourism and hunting tourism in particular in order to evaluate their development as a lucrative type of investment, while considering the including promotional activities. Certain disadvantages and problems that Serbian hunting tourism has been facing as well as the directions for their solution are addressed in the paper.

关键词： Rural tourism hunting tourism marketing management tourism promotion.

Study on spiral winding swimming motion control of a slender legless creature model

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High Technology Letters 2021年第4期27卷 415-421页

作者： Lu Zhenli Ma Zhipeng Marko Pencic Maja Cavic Borovac branislav Roumiana Ilieva Bojan Nemec Marjan Mernik School of Electrical Engineering and Automation Changshu Institute of TechnologyChangshu 215500P.R.China School of Information and Control Engineering China University of Mining and TechnologyXuzhou 221116P.R.China Faculty of Technical Sciences University of Novi SadNovi Sad 621000Serbia Faculty of Management Technical University of SofiaSofia 1000Bulgaria Department of Automatics Biocybernetics and RoboticsJožef Stefan InstituteLjubljana 1000Slovenia Faculty of Electrical Engineering and Computer Science University of MariborMaribor 462000Slovenia

Through the observation and analysis of the motion trajectory of spiral winding motion for slender legless biological creatures in water,V-REP software is adopted to build a dynamic simulator to study on the mechanism of spiral winding swimming(SWS)*** using the output of spiral function(SF),the dynamic simulation model of slender legless creature(SLC)realizes the SWS motion in *** corresponding experiments under the control of different bending angle of SF to control the dynamic model are also carried out to analyze the water performance of SWS in still *** with the output of two different bending angles of the spiral function,the dynamic model can be used to realize SWS and up/down *** work provides technical reserve and experimental platform for the corresponding study in related fields.

关键词： V-REP spiral winding swimming(SWS) motion control slender legless creature(SLC)

Auxiliary Software for Defining the Parameters of the Structural Organization of a Complex System

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Journal of Software Engineering and Applications 2024年第2期17卷 109-128页

作者： branislav M. Savic Department of Thermal Power Engineering Faculty of Mechanical Engineering University of Belgrade Belgrade Serbia

The developed auxiliary software serves to simplify, standardize and facilitate the software loading of the structural organization of a complex technological system, as well as its further manipulation within the process of solving the considered technological system. Its help can be especially useful in the case of a complex structural organization of a technological system with a large number of different functional elements grouped into several technological subsystems. This paper presents the results of its application for a special complex technological system related to the reference steam block for the combined production of heat and electricity.

关键词： Complex System Structural Organization Auxiliary Software Parameters