检索结果-南通市图书馆

维普期刊数据库

Biofuel cell based on horseradish peroxidase immobilized on copper sulfide as anode for decolorization of anthraquinone AV109 dye

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2016年第3期25卷 403-408页

作者： natasa Z.sekuljica Milica M.Gvozdenovic Zorica D.Knezevic-Jugovic branimir Z.Jugovic branimir n.grgur Innovation Center Faculty of Technology and Metallurgy University of Belgrade Karnegijeva 4 11020 Belgrade Serbia Faculty of Technology and Metallurgy University of Belgrade Karnegijeva 4 11020 Belgrade Serbia Institute of Technical Sciences of the Serbian Academy of Sciences and Arts Knez Mihailova 35/IV 11000 Belgrade Serbia

The potential application of electrochemically formed copper sulfide as horseradish peroxidase mediator in the enzymatic biofuel cell and anthraquinone AV109 dye as a fuel is investigated. The open circuit voltage of 0.52 V and short circuit current of ～3.6 μA/cm^2 are obtained, with the maximum specific power of ～1 μW/cm^2. The influence of internal resistance of the cell is discussed. Decolorization is investigated under open circuit potentials, and under external load of 3.3 k conditions. In both cases, 40% of decolorization is achieved, but are three times faster under external load conditions. Specific energy during decolorization in such cell is estimated to ～5 m Wh/m^2. The possible mechanism of the power generation during decolorization of AV 109 dye is discussed.

关键词：酵素介体过氧化氢氧还原

维普期刊数据库

转录因子HnF1A、HnF4A和FOXA2调节肝细胞蛋白质n-糖基化

在线全文

学校读者我要写书评

暂无评论

Engineering 2024年第1期32卷 57-68页

作者： Vedrana Vicic Bockor nika Foglar Goran Josipovic Marija Klasic Ana Vujic branimir Plavsa Toma Keser Samira Smajlovic Aleksandar Vojta Vlatka Zoldos Laboratory for Epigenetics Department of BiologyFaculty of ScienceUniversity of ZagrebZagreb 10000Croatia Genos Glycoscience Research Laboratory Zagreb 10000Croatia Faculty of Pharmacy and Biochemistry University of ZagrebZagreb 10000Croatia

Hepatocyte nuclear factor 1 alpha(HnF1A),hepatocyte nuclear factor 4 alpha(HnF4A),and forkhead box protein A2(FOXA2)are key transcription factors that regulate a complex gene network in the liver,cre-ating a regulatory transcriptional *** Encode and ChIP-Atlas databases identify the recognition sites of these transcription factors in many glycosyltransferase *** in silico analysis of HnF1A,*** FOXA2 binding to the ten candidate glyco-genes studied in this work confirms a significant enrich-ment of these transcription factors specifically in the *** previous studies identified HnF1A as a master regulator of fucosylation,glycan branching,and galactosylation of plasma ***,we aimed to functionally validate the role of the three transcription factors on downstream glyco-gene transcriptional expression and the possible effect on glycan *** used the state-of-the-art clus-tered regularly interspaced short palindromic repeats/dead Cas9(CRISPR/dCas9)molecular tool for the downregulation of the HnF1A,HnF4A,and FOXA2 genes in HepG2 cells-a human liver cancer cell *** results show that the downregulation of all three genes individually and in pairs affects the transcrip-tional activity of many glyco-genes,although downregulation of glyco-genes was not always followed by an unambiguous change in the corresponding glycan *** effect is better seen as an overall change in the total HepG2 n-glycome,primarily due to the extension of biantennary *** propose an alternative way to evaluate the n-glycome composition via estimating the overall complexity of the glycome by quantifying the number of monomers in each glycan *** also propose a model showing feedback loops with the mutual activation of HnF1A-FOXA2 and HnF4A-FOXA2 affecting glyco-genes and protein glycosylation in HepG2 cells.

关键词： Clustered regularly interspaced short palindromic repeats/dead Cas9(CRISPR/dCas9) Epigenetics Hepatocyte nuclear factor 1 alpha(HnF1A) Hepatocyte nuclear factor 4 alpha(HnF4A) Forkhead box protein A2(FOXA2) n-glycosylation HepG2 cells

转录因子HnF1A、HnF4A和FOXA2调节肝细胞蛋白质n-糖基化（英文）

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Engineering 2024年第1期 57-68页

作者： Vedrana Vi?i? Bo?kor nika Foglar Goran Josipovi? Marija Klasi? Ana Vuji? branimir Plav?a Toma Keser Samira Smajlovi? Aleksandar Vojta Vlatka Zoldo? Laboratory for Epigenetics Department of Biology Faculty of Science University of Zagreb Genos Glycoscience Research Laboratory Faculty of Pharmacy and Biochemistry University of Zagreb

Hepatocyte nuclear factor 1 alpha(HnF1A),hepatocyte nuclear factor 4 alpha(HnF4A),and forkhead box protein A2(FOXA2) are key transcription factors that regulate a complex gene network in the liver,creating a regulatory transcriptional *** Encode and ChIP-Atlas databases identify the recognition sites of these transcription factors in many glycosyltransferase *** in silico analysis of HnF1A,HnF4A,and FOXA2 binding to the ten candidate glyco-genes studied in this work confirms a significant enrichment of these transcription factors specifically in the *** previous studies identified HnF1A as a master regulator of fucosylation,glycan branching,and galactosylation of plasma ***,we aimed to functionally validate the role of the three transcription factors on downstream glyco-gene transcriptional expression and the possible effect on glycan *** used the state-of-the-art clustered regularly interspaced short palindromic repeats/dead Cas9(CRISPR/dCas9) molecular tool for the downregulation of the HnF1A,HnF4A,and FOXA2 genes in HepG2 cells-a human liver cancer cell *** results show that the downregulation of all three genes individually and in pairs affects the transcriptional activity of many gly co-genes,although downregulation of glyco-genes was not always followed by an unambiguous change in the corresponding glycan *** effect is better seen as an overall change in the total HepG2 n-glycome,primarily due to the extension of biantenna ry *** propose an alternative way to evaluate the n-glycome composition via estimating the overall complexity of the glycome by quantifying the number of monomers in each glycan *** also propose a model showing feedback loops with the mutual activation of HnF1A-FOXA2 and HnF4A-FOXA2 affecting glyco-genes and protein glycosylation in HepG2 cells.

关键词：

Geochemistry of Sediments from the Lopare Basin(Bosnia and Herzegovina):Implications for Paleoclimate,Paleosalinity,Paleoredox and Provenance

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Acta Geologica Sinica(English Edition) 2020年第5期94卷 1591-1618页

作者： AleksandraŠAJnOVIĆ nenad GRBA Franz nEUBAUER Milica KAŠAnIn-GRUBIn Ksenija STOJAnOVIĆ nenad PETKOVIĆ branimir JOVAnČIĆEVIĆ University of Belgrade Center of ChemistryICTMStudentski trg 12-1611000 BelgradeSerbia University of novi Sad Faculty of SciencesDepartment of ChemistryBiochemistry and Environmental ProtectionTrg Dositeja Obradovica 321000 Novi SadSerbia Paris Lodron University of Salzburg Department of Geography and GeologyHellbrunnerstrasse 345020 SalzburgAustria University of Belgrade Faculty of ChemistryStudentski trg 12-1611000 BelgradeSerbia Rio Tinto–Rio Sava Exploration Takovska 4511000 BelgradeSerbia

A combined inorganic and organic geochemical study was carried out on marls and mudstones collected from the Lower Miocene Lopare Basin,Bosnia and Herzegovina.A total of 46 samples collected from two boreholes,Pot 1(depth of 193 m)and Pot 3(depth of 344 m),showed that element abundances like boron(B),lithium(Li),strontium(Sr),uranium(U),chromium(Cr),nickel(ni),magnesium(Mg),sodium(na)and calcium(Ca)are much higher than average than in the upper continental crust(UCC).Chemical composition indicates at least two sources:(i)Mesozoic ophiolites occurring in the north of the investigated area,and(ii)dacito-andesitic pyroclastics(Mesozoic to Cenozoic).Lopare Basin sedimentation was influenced by strong evaporation resulting in a partly hypersaline lake,which formed during a warm climatic period,probably during the Miocene Climatic Optimum.A brief episode of humid climate conditions resulted in the basin fillingup and deposition of felsic sediments enriched in thorium(Th).Organic geochemistry shows that the majority of studied sediments contains predominantly immature to marginally mature algal organic matter(OM).The biomarker patterns are generally in agreement with the geological history of the Lopare Basin and inorganic and mineralogical ***,the molecular distribution of n-alkanes as reliable climatic andδ-MTTC as paleosalinity indicators do not support this conclusion.

关键词： geochemistry provenance analysis paleoenvironmental conditions salinity/hypersalinity biomarker Lopare Basin Bosnia and Herzegovina

维普期刊数据库